Compile Data Set for Download or QSAR
Found 140 with Last Name = 'nigade' and Initial = 'pb'
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50446130(AG-014699 | AG-14447 | RUCAPARIB CAMSYLATE | Rucap...)copy SMILEScopy InChI
Affinity DataKi:  0.700nMAssay Description:Inhibition of N-terminal GST-tagged human PARP2 (2 to 583 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H2A and H2B) a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N84R1PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50446130(AG-014699 | AG-14447 | RUCAPARIB CAMSYLATE | Rucap...)copy SMILEScopy InChI
Affinity DataKi:  1.40nMAssay Description:Inhibition of N-terminal GST-tagged human full length PARP1 (2 to 1041 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H...More data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Lupin Ltd.

Curated by ChEMBL
LigandPNGBDBM371616((R)-4-(2-(6-Fluoropyridin-3-yl)-4-(trifluoromethyl...)copy SMILEScopy InChI
Affinity DataIC50: 0.110nMAssay Description:Inhibition of Nav1.7 (unknown origin) expressed in HEK293 cells assessed as reduction in veratridine-induced depolarization preincubated for 15 to 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69P5CPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50548675(CHEMBL4800042)copy SMILES
Affinity DataIC50: 0.400nMAssay Description:Inhibition of N-terminal GST-tagged human full length PARP1 (2 to 1041 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N84R1PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Lupin Ltd.

Curated by ChEMBL
LigandPNGBDBM50545560(CHEMBL4634421)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of Nav1.7 (unknown origin) expressed in HEK293 cells assessed as reduction in veratridine-induced depolarization preincubated for 15 to 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69P5CPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Lupin Ltd.

Curated by ChEMBL
LigandPNGBDBM50545552(CHEMBL4646742)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of Nav1.7 (unknown origin) expressed in HEK293 cells assessed as reduction in veratridine-induced depolarization preincubated for 15 to 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69P5CPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Lupin Ltd.

Curated by ChEMBL
LigandPNGBDBM50545563(CHEMBL4636838)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of Nav1.7 (unknown origin) expressed in HEK293 cells assessed as reduction in veratridine-induced depolarization preincubated for 15 to 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69P5CPubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))TBA
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of N-terminal GST-tagged human PARP2 (2 to 583 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H2A and H2B) a...More data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Lupin Ltd.

Curated by ChEMBL
LigandPNGBDBM50545558(CHEMBL4642748)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of Nav1.7 (unknown origin) expressed in HEK293 cells assessed as reduction in veratridine-induced depolarization preincubated for 15 to 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69P5CPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50548674(CHEMBL4787850)copy SMILES
Affinity DataIC50: 0.600nMAssay Description:Inhibition of N-terminal GST-tagged human full length PARP1 (2 to 1041 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N84R1PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50548679(CHEMBL4747106)copy SMILES
Affinity DataIC50: 0.600nMAssay Description:Inhibition of N-terminal GST-tagged human full length PARP1 (2 to 1041 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N84R1PubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50084621(BMN 673 | Talazoparib)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of N-terminal GST-tagged human PARP2 (2 to 583 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H2A and H2B) a...More data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Lupin Ltd.

Curated by ChEMBL
LigandPNGBDBM371523((R)-N-(6-Fluoropyridin-2-yl)-4-(2-(1-methyl-1H-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of Nav1.7 (unknown origin) expressed in HEK293 cells assessed as reduction in veratridine-induced depolarization preincubated for 15 to 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69P5CPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50548673(CHEMBL4748390)copy SMILES
Affinity DataIC50: 0.600nMAssay Description:Inhibition of N-terminal GST-tagged human full length PARP1 (2 to 1041 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N84R1PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50446130(AG-014699 | AG-14447 | RUCAPARIB CAMSYLATE | Rucap...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of N-terminal GST-tagged human full length PARP1 (2 to 1041 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H...More data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Lupin Ltd.

Curated by ChEMBL
LigandPNGBDBM50545567(CHEMBL4649638)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Inhibition of Nav1.7 (unknown origin) expressed in HEK293 cells assessed as reduction in veratridine-induced depolarization preincubated for 15 to 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69P5CPubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50446130(AG-014699 | AG-14447 | RUCAPARIB CAMSYLATE | Rucap...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Inhibition of N-terminal GST-tagged human PARP2 (2 to 583 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H2A and H2B) a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N84R1PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50548676(CHEMBL4786854)copy SMILES
Affinity DataIC50: 0.800nMAssay Description:Inhibition of N-terminal GST-tagged human full length PARP1 (2 to 1041 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N84R1PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50548672(CHEMBL4781887)copy SMILES
Affinity DataIC50: 0.900nMAssay Description:Inhibition of N-terminal GST-tagged human full length PARP1 (2 to 1041 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N84R1PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50548683(CHEMBL4789581)copy SMILES
Affinity DataIC50: 0.900nMAssay Description:Inhibition of N-terminal GST-tagged human full length PARP1 (2 to 1041 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N84R1PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50548681(CHEMBL4753410)copy SMILES
Affinity DataIC50: 0.900nMAssay Description:Inhibition of N-terminal GST-tagged human full length PARP1 (2 to 1041 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N84R1PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of N-terminal GST-tagged human full length PARP1 (2 to 1041 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50548677(CHEMBL4755076)copy SMILES
Affinity DataIC50: 1nMAssay Description:Inhibition of N-terminal GST-tagged human full length PARP1 (2 to 1041 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N84R1PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50084621(BMN 673 | Talazoparib)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of N-terminal GST-tagged human full length PARP1 (2 to 1041 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50548684(CHEMBL4746309)copy SMILES
Affinity DataIC50: 1nMAssay Description:Inhibition of N-terminal GST-tagged human full length PARP1 (2 to 1041 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N84R1PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Lupin Ltd.

Curated by ChEMBL
LigandPNGBDBM371635((R)-4-(2-(1H-1,2,3-Triazol-1-yl)-4-(trifluoromethy...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of Nav1.7 (unknown origin) expressed in HEK293 cells assessed as reduction in veratridine-induced depolarization preincubated for 15 to 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69P5CPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50548685(CHEMBL4776820)copy SMILES
Affinity DataIC50: 1.10nMAssay Description:Inhibition of N-terminal GST-tagged human full length PARP1 (2 to 1041 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N84R1PubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50548677(CHEMBL4755076)copy SMILES
Affinity DataIC50: 1.30nMAssay Description:Inhibition of N-terminal GST-tagged human PARP2 (2 to 583 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H2A and H2B) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N84R1PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Lupin Ltd.

Curated by ChEMBL
LigandPNGBDBM371776((R)-4-(2-(6-methylpyridin-3-yl)-4-(trifluoromethyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of Nav1.7 (unknown origin) expressed in HEK293 cells assessed as reduction in veratridine-induced depolarization preincubated for 15 to 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69P5CPubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50548679(CHEMBL4747106)copy SMILES
Affinity DataIC50: 1.5nMAssay Description:Inhibition of N-terminal GST-tagged human PARP2 (2 to 583 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H2A and H2B) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N84R1PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Lupin Ltd.

Curated by ChEMBL
LigandPNGBDBM371648((R)-N-(6-Fluoropyridin-2-yl)-4-(2-(2-methyloxazol-...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of Nav1.7 (unknown origin) expressed in HEK293 cells assessed as reduction in veratridine-induced depolarization preincubated for 15 to 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69P5CPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Lupin Ltd.

Curated by ChEMBL
LigandPNGBDBM50545554(CHEMBL4635247)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of Nav1.7 (unknown origin) expressed in HEK293 cells assessed as reduction in veratridine-induced depolarization preincubated for 15 to 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69P5CPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Lupin Ltd.

Curated by ChEMBL
LigandPNGBDBM371652((R)-4-(2-(2-methyloxazol-4-yl)-4-(trifluoromethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of Nav1.7 (unknown origin) expressed in HEK293 cells assessed as reduction in veratridine-induced depolarization preincubated for 15 to 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69P5CPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Lupin Ltd.

Curated by ChEMBL
LigandPNGBDBM371770((R)-4-(2-(5-fluoropyridin-2-yl)-4-(trifluoromethyl...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Inhibition of Nav1.7 (unknown origin) expressed in HEK293 cells assessed as reduction in veratridine-induced depolarization preincubated for 15 to 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69P5CPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Lupin Ltd.

Curated by ChEMBL
LigandPNGBDBM50545556(CHEMBL4639228)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Inhibition of Nav1.7 (unknown origin) expressed in HEK293 cells assessed as reduction in veratridine-induced depolarization preincubated for 15 to 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69P5CPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Lupin Ltd.

Curated by ChEMBL
LigandPNGBDBM371697(N-(6-fluoropyridin-2-yl)-4-(2-morpholino-4-(triflu...)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Inhibition of Nav1.7 (unknown origin) expressed in HEK293 cells assessed as reduction in veratridine-induced depolarization preincubated for 15 to 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69P5CPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50548680(CHEMBL4741921)copy SMILES
Affinity DataIC50: 2.5nMAssay Description:Inhibition of N-terminal GST-tagged human full length PARP1 (2 to 1041 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N84R1PubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50548681(CHEMBL4753410)copy SMILES
Affinity DataIC50: 2.60nMAssay Description:Inhibition of N-terminal GST-tagged human PARP2 (2 to 583 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H2A and H2B) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N84R1PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Lupin Ltd.

Curated by ChEMBL
LigandPNGBDBM371768((R)-4-(2-(5-fluoropyridin-2-yl)-4-(trifluoromethyl...)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Inhibition of Nav1.7 (unknown origin) expressed in HEK293 cells assessed as reduction in veratridine-induced depolarization preincubated for 15 to 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69P5CPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Lupin Ltd.

Curated by ChEMBL
LigandPNGBDBM371614((R)-4-(2-(6-Fluoropyridin-3-yl)-4-(trifluoromethyl...)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Inhibition of Nav1.7 (unknown origin) expressed in HEK293 cells assessed as reduction in veratridine-induced depolarization preincubated for 15 to 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69P5CPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Lupin Ltd.

Curated by ChEMBL
LigandPNGBDBM371695(4-(2-morpholino-4-(trifluoromethyl)phenyl)-N-(pyri...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of Nav1.7 (unknown origin) expressed in HEK293 cells assessed as reduction in veratridine-induced depolarization preincubated for 15 to 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69P5CPubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50548673(CHEMBL4748390)copy SMILES
Affinity DataIC50: 3.90nMAssay Description:Inhibition of N-terminal GST-tagged human PARP2 (2 to 583 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H2A and H2B) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N84R1PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Lupin Ltd.

Curated by ChEMBL
LigandPNGBDBM371584((R)-4-(2-(1-Methyl-1H-pyrazol-5-yl)-4-(trifluorome...)copy SMILEScopy InChI
Affinity DataIC50: 4.30nMAssay Description:Inhibition of Nav1.7 (unknown origin) expressed in HEK293 cells assessed as reduction in veratridine-induced depolarization preincubated for 15 to 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69P5CPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Lupin Ltd.

Curated by ChEMBL
LigandPNGBDBM50545561(CHEMBL4641467)copy SMILEScopy InChI
Affinity DataIC50: 4.5nMAssay Description:Inhibition of Nav1.7 (unknown origin) expressed in HEK293 cells assessed as reduction in veratridine-induced depolarization preincubated for 15 to 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69P5CPubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50548675(CHEMBL4800042)copy SMILES
Affinity DataIC50: 4.60nMAssay Description:Inhibition of N-terminal GST-tagged human PARP2 (2 to 583 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H2A and H2B) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N84R1PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50548678(CHEMBL4777158)copy SMILES
Affinity DataIC50: 5nMAssay Description:Inhibition of N-terminal GST-tagged human full length PARP1 (2 to 1041 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N84R1PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50548682(CHEMBL4776507)copy SMILES
Affinity DataIC50: 5.60nMAssay Description:Inhibition of N-terminal GST-tagged human full length PARP1 (2 to 1041 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N84R1PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Lupin Ltd.

Curated by ChEMBL
LigandPNGBDBM50545566(CHEMBL4642855)copy SMILEScopy InChI
Affinity DataIC50: 6.20nMAssay Description:Inhibition of Nav1.7 (unknown origin) expressed in HEK293 cells assessed as reduction in veratridine-induced depolarization preincubated for 15 to 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69P5CPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Lupin Ltd.

Curated by ChEMBL
LigandPNGBDBM371540((R)-N-(4-Fluoropyridin-2-yl)-4-(2-(1-methyl-1H-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 6.5nMAssay Description:Inhibition of Nav1.7 (unknown origin) expressed in HEK293 cells assessed as reduction in veratridine-induced depolarization preincubated for 15 to 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69P5CPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Lupin Ltd.

Curated by ChEMBL
LigandPNGBDBM371780(N-(6-fluoropyridin-2-yl)-4-(2-(6-methylpyridin-3-y...)copy SMILEScopy InChI
Affinity DataIC50: 6.60nMAssay Description:Inhibition of Nav1.7 (unknown origin) expressed in HEK293 cells assessed as reduction in veratridine-induced depolarization preincubated for 15 to 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69P5CPubMed
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