Compile Data Set for Download or QSAR
Found 849 with Last Name = 'hughes' and Initial = 'pe'
LigandPNGBDBM50514220(CHEMBL4535151 | US11274105, Example 188)copy SMILEScopy InChI
Affinity DataKi:  0.0400nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ64WWPubMed
LigandPNGBDBM50514222(CHEMBL4580244 | US11274105, Example 193)copy SMILEScopy InChI
Affinity DataKi:  0.0500nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ64WWPubMed
LigandPNGBDBM50514203(CHEMBL4593361 | US11274105, Example 6)copy SMILEScopy InChI
Affinity DataKi:  0.0500nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ64WWPubMed
LigandPNGBDBM50514196(CHEMBL4476472)copy SMILEScopy InChI
Affinity DataKi:  0.0510nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
LigandPNGBDBM50514202(CHEMBL4446369 | US11274105, Example 179)copy SMILEScopy InChI
Affinity DataKi:  0.0600nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
LigandPNGBDBM50514199(CHEMBL4553660 | US11274105, Example 182)copy SMILEScopy InChI
Affinity DataKi:  0.0700nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ64WWPubMed
LigandPNGBDBM50514200(CHEMBL4446378 | US10703733, Comparative Example 1)copy SMILEScopy InChI
Affinity DataKi:  0.0760nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
LigandPNGBDBM50514215(CHEMBL4577379 | US11274105, Example 4)copy SMILEScopy InChI
Affinity DataKi:  0.0900nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ64WWPubMed
LigandPNGBDBM50514216(CHEMBL4528051 | US11274105, Example 5)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
LigandPNGBDBM50514214(CHEMBL4542646 | US11274105, Example 41)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
LigandPNGBDBM50514219(CHEMBL4438074 | US11274105, Example 181)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ64WWPubMed
LigandPNGBDBM50514218(CHEMBL4539543 | US11274105, Example 197)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ64WWPubMed
LigandPNGBDBM50514206(CHEMBL4588330 | US11274105, Example 187)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ64WWPubMed
LigandPNGBDBM50514201(CHEMBL4547370 | US11274105, Example 191)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ64WWPubMed
LigandPNGBDBM50514204(CHEMBL4437832)copy SMILEScopy InChI
Affinity DataKi:  0.110nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ64WWPubMed
LigandPNGBDBM50514217(CHEMBL4452794 | US11274105, Example 196)copy SMILEScopy InChI
Affinity DataKi:  0.200nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ64WWPubMed
LigandPNGBDBM50514208(CHEMBL4469850 | US11274105, Example 61)copy SMILEScopy InChI
Affinity DataKi:  0.280nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ64WWPubMed
LigandPNGBDBM50514207(CHEMBL4562159)copy SMILEScopy InChI
Affinity DataKi:  0.370nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ64WWPubMed
LigandPNGBDBM50401261(CHEMBL2206921 | US8772480, 384)copy SMILEScopy InChI
Affinity DataKi:  0.400nMAssay Description:Inhibition of human N-terminal polyHis-tagged PI3K p110delta expressed in baculovirus infected Hi5 cells using Phosphatidylinositol-4,5-bisphosphate ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7QNWPubMed
LigandPNGBDBM50514197(CHEMBL4561691 | US11274105, Example 63)copy SMILEScopy InChI
Affinity DataKi:  0.5nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
LigandPNGBDBM50357645(CHEMBL1738719)copy SMILEScopy InChI
Affinity DataKi:  0.600nMAssay Description:Inhibition of N-terminus polyHis-tagged human recombinant PI3Kalpha expressed in baculovirus infected insect Sf9 cells using phosphoinositol-4,5-bisp...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB53C5PubMed
LigandPNGBDBM50401261(CHEMBL2206921 | US8772480, 384)copy SMILEScopy InChI
Affinity DataKi:  0.600nMAssay Description:Inhibition of human N-terminal polyHis-tagged PI3K p110beta expressed in baculovirus infected Hi5 cells using Phosphatidylinositol-4,5-bisphosphate a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7QNWPubMed
LigandPNGBDBM50119621(CHEMBL3618245)copy SMILEScopy InChI
Affinity DataKi:  0.600nMAssay Description:Inhibition of PI3Kdelta (unknown origin) by alpha screen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SKCPubMed
LigandPNGBDBM50357674(CHEMBL1914739)copy SMILEScopy InChI
Affinity DataKi:  0.600nMAssay Description:Inhibition of N-terminus polyHis-tagged human recombinant PI3Kalpha expressed in baculovirus infected insect Sf9 cells using phosphoinositol-4,5-bisp...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB53C5PubMed
LigandPNGBDBM50357652(CHEMBL1914726)copy SMILEScopy InChI
Affinity DataKi:  0.700nMAssay Description:Inhibition of N-terminus polyHis-tagged human recombinant PI3Kalpha expressed in baculovirus infected insect Sf9 cells using phosphoinositol-4,5-bisp...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB53C5PubMed
LigandPNGBDBM50357665(CHEMBL1914728)copy SMILEScopy InChI
Affinity DataKi:  0.700nMAssay Description:Inhibition of N-terminus polyHis-tagged human recombinant PI3Kalpha expressed in baculovirus infected insect Sf9 cells using phosphoinositol-4,5-bisp...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB53C5PubMed
LigandPNGBDBM50357650(CHEMBL1914742)copy SMILEScopy InChI
Affinity DataKi:  0.800nMAssay Description:Inhibition of N-terminus polyHis-tagged human recombinant PI3Kalpha expressed in baculovirus infected insect Sf9 cells using phosphoinositol-4,5-bisp...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB53C5PubMed
LigandPNGBDBM50357668(CHEMBL1914731)copy SMILEScopy InChI
Affinity DataKi:  0.800nMAssay Description:Inhibition of N-terminus polyHis-tagged human recombinant PI3Kalpha expressed in baculovirus infected insect Sf9 cells using phosphoinositol-4,5-bisp...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB53C5PubMed
LigandPNGBDBM50357670(CHEMBL1914734)copy SMILEScopy InChI
Affinity DataKi:  0.800nMAssay Description:Inhibition of N-terminus polyHis-tagged human recombinant PI3Kalpha expressed in baculovirus infected insect Sf9 cells using phosphoinositol-4,5-bisp...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB53C5PubMed
LigandPNGBDBM50357653(CHEMBL1914727)copy SMILEScopy InChI
Affinity DataKi:  0.800nMAssay Description:Inhibition of N-terminus polyHis-tagged human recombinant PI3Kalpha expressed in baculovirus infected insect Sf9 cells using phosphoinositol-4,5-bisp...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB53C5PubMed
LigandPNGBDBM50351949(CHEMBL1822054)copy SMILEScopy InChI
Affinity DataKi:  0.800nMAssay Description:Inhibition of human N-terminal His-tagged PI3Kdelta expressed in insect Sf9 cells using PI(4,5)P2 as substrate after 20 mins by alphascreen assay in ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V12567PubMed
LigandPNGBDBM50357673(CHEMBL1914738)copy SMILEScopy InChI
Affinity DataKi:  0.900nMAssay Description:Inhibition of N-terminus polyHis-tagged human recombinant PI3Kalpha expressed in baculovirus infected insect Sf9 cells using phosphoinositol-4,5-bisp...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB53C5PubMed
LigandPNGBDBM50357651(CHEMBL1914724)copy SMILEScopy InChI
Affinity DataKi:  0.900nMAssay Description:Inhibition of N-terminus polyHis-tagged human recombinant PI3Kalpha expressed in baculovirus infected insect Sf9 cells using phosphoinositol-4,5-bisp...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB53C5PubMed
LigandPNGBDBM50357666(CHEMBL1914729)copy SMILEScopy InChI
Affinity DataKi:  0.900nMAssay Description:Inhibition of N-terminus polyHis-tagged human recombinant PI3Kalpha expressed in baculovirus infected insect Sf9 cells using phosphoinositol-4,5-bisp...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB53C5PubMed
LigandPNGBDBM50357662(CHEMBL1914721)copy SMILEScopy InChI
Affinity DataKi:  0.900nMAssay Description:Inhibition of PI3Kalpha-mediated Akt phosphorylation at Ser 473 in human U87MG cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB53C5PubMed
LigandPNGBDBM50357675(CHEMBL1914740)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Inhibition of N-terminus polyHis-tagged human recombinant PI3Kalpha expressed in baculovirus infected insect Sf9 cells using phosphoinositol-4,5-bisp...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB53C5PubMed
LigandPNGBDBM50396807(CHEMBL2170082 | US8772480, 316)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Inhibition of human N-terminal polyHis-tagged PI3K p110delta/p85alpha expressed in baculovirus infected Sf9 cells using phosphatidylinositol-4,5-bisp...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028SPTPubMed
LigandPNGBDBM50396806(CHEMBL2170083 | US8772480, 270)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Inhibition of human N-terminal polyHis-tagged PI3K p110delta/p85alpha expressed in baculovirus infected Sf9 cells using phosphatidylinositol-4,5-bisp...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028SPTPubMed
LigandPNGBDBM50514209(CHEMBL4460664)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ64WWPubMed
LigandPNGBDBM50401261(CHEMBL2206921 | US8772480, 384)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Inhibition of human N-terminal polyHis-tagged PI3K p110gamma expressed in baculovirus infected Hi5 cells using Phosphatidylinositol-4,5-bisphosphate ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7QNWPubMed
LigandPNGBDBM50514205(CHEMBL4452403)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ64WWPubMed
LigandPNGBDBM50396808(CHEMBL2170081 | US8772480, 148)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Inhibition of human N-terminal polyHis-tagged PI3K p110gamma expressed in baculovirus infected Hi5 cells using ATP as substrate after 20 mins by spec...More data for this Ligand-Target Pair
LigandPNGBDBM50396820(CHEMBL2170088 | US8772480, 272)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Inhibition of human N-terminal polyHis-tagged PI3K p110alpha/p85alpha expressed in baculovirus infected Sf9 cells using phosphatidylinositol-4,5-bisp...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028SPTPubMed
LigandPNGBDBM50394838(CHEMBL2165007 | US8772480, 141)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Inhibition of human N-terminal poly-His tagged-PI3Kdelta expressed in Sf9 baculovirus system co-expressing p85alpha after 20 mins by AlphaScreen assa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4QSJPubMed
LigandPNGBDBM50357644(CHEMBL1914947)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Inhibition of N-terminus polyHis-tagged human recombinant PI3Kalpha expressed in baculovirus infected insect Sf9 cells using phosphoinositol-4,5-bisp...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB53C5PubMed
LigandPNGBDBM50357664(CHEMBL1914723)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Inhibition of PI3Kalpha-mediated Akt phosphorylation at Ser 473 in human U87MG cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB53C5PubMed
LigandPNGBDBM50357667(CHEMBL1914730)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Inhibition of PI3Kalpha-mediated Akt phosphorylation at Ser 473 in human U87MG cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB53C5PubMed
LigandPNGBDBM50396809(CHEMBL2170099 | US8772480, 147)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Inhibition of human N-terminal polyHis-tagged PI3K p110delta/p85alpha expressed in baculovirus infected Sf9 cells using phosphatidylinositol-4,5-bisp...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028SPTPubMed
LigandPNGBDBM50401256(CHEMBL2206904 | US8772480, 331)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:Inhibition of human N-terminal polyHis-tagged PI3K p110delta expressed in baculovirus infected Hi5 cells using Phosphatidylinositol-4,5-bisphosphate ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7QNWPubMed
LigandPNGBDBM50343200(CHEMBL1615189 | N-(6-(6-Chloro-5-(4-fluorophenylsu...)copy SMILEScopy InChI
Affinity DataKi:  1.20nMAssay Description:Inhibition of human PI3Kalpha using PI(4,5)P2 as substrate after 20 mins by alphascreen assay in presence of 20 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V12567PubMed
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