Compile Data Set for Download or QSAR
Found 104 with Last Name = 'leroy' and Initial = 'pj'
TargetAurora kinase A(Mus musculus (mouse))
Takeda Pharmaceuticals International Co. , 40 Landsdowne Street, Cambridge, Massachusetts 02139, United States.

Curated by ChEMBL
LigandPNGBDBM50277545(4-(9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-benzo[...)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:Competitive inhibition of recombinant mouse aurora kinase A expressed in insect Sf9 cells in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8W1VPubMed
TargetAurora kinase A(Mus musculus (mouse))
Takeda Pharmaceuticals International Co. , 40 Landsdowne Street, Cambridge, Massachusetts 02139, United States.

Curated by ChEMBL
LigandPNGBDBM31093(4-[[7-[2,6-bis(fluoranyl)phenyl]-9-chloranyl-5H-py...)copy SMILEScopy InChI
Affinity DataKi:  7nMAssay Description:Competitive inhibition of recombinant mouse aurora kinase A expressed in insect Sf9 cells in presence of ATPMore data for this Ligand-Target Pair
TargetAurora kinase A(Mus musculus (mouse))
Takeda Pharmaceuticals International Co. , 40 Landsdowne Street, Cambridge, Massachusetts 02139, United States.

Curated by ChEMBL
LigandPNGBDBM50277545(4-(9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-benzo[...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant mouse aurora kinase A expressed in insect Sf9 cells using biotin-GLRRASLG as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8W1VPubMed
TargetAurora kinase A(Mus musculus (mouse))
Takeda Pharmaceuticals International Co. , 40 Landsdowne Street, Cambridge, Massachusetts 02139, United States.

Curated by ChEMBL
LigandPNGBDBM31093(4-[[7-[2,6-bis(fluoranyl)phenyl]-9-chloranyl-5H-py...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of mouse recombinant Aurora A kinase expressed in insect Sf9 cells by radioactive flashplate assayMore data for this Ligand-Target Pair
TargetAurora kinase A(Homo sapiens (Human))
Takeda Pharmaceuticals International Co. , 40 Landsdowne Street, Cambridge, Massachusetts 02139, United States.

Curated by ChEMBL
LigandPNGBDBM50277545(4-(9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-benzo[...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of aurora kinase A autophosphorylation at T288 in human HCT116 cells by immunofluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8W1VPubMed
TargetAurora kinase A(Mus musculus (mouse))
Takeda Pharmaceuticals International Co. , 40 Landsdowne Street, Cambridge, Massachusetts 02139, United States.

Curated by ChEMBL
LigandPNGBDBM50097413(CHEMBL3586473)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant mouse aurora kinase A expressed in insect Sf9 cells using biotin-GLRRASLG as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8W1VPubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))TBA
LigandPNGBDBM475984(US10865208, Compound I-42 | {(2R,3S,4R,5R)-5-[4-am...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90DBRPubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))TBA
LigandPNGBDBM475978(US10865208, Compound I-36 | {(2R,3S,4R,5R)-5-[4-am...)copy SMILES
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90DBRPubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))TBA
LigandPNGBDBM476001(US10865208, Compound I-58 | {(2R,3S,4R,5R)-5-[4-am...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90DBRPubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))TBA
LigandPNGBDBM476012(US10865208, Compound I-69 | [(2R,3S,4R,5R)-5-{4-am...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90DBRPubMed
TargetAurora kinase A(Homo sapiens (Human))
Takeda Pharmaceuticals International Co. , 40 Landsdowne Street, Cambridge, Massachusetts 02139, United States.

Curated by ChEMBL
LigandPNGBDBM50097413(CHEMBL3586473)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of aurora kinase A autophosphorylation at T288 in human HCT116 cells by immunofluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8W1VPubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))TBA
LigandPNGBDBM476084(US10865208, Compound I-139 | {(2R,3R,4S,5R)-5-[4-a...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90DBRPubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))TBA
LigandPNGBDBM475993(US10865208, Compound I-51 | {(2R,3S,4R,5R)-5-[4-am...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90DBRPubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))TBA
LigandPNGBDBM475994(US10865208, Compound I-52 | {(2R,3S,4R,5R)-5-[4-am...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90DBRPubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))TBA
LigandPNGBDBM476126(US10865208, Compound I-181 | {(2R,3S,5R)-5-[4-amin...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90DBRPubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))TBA
LigandPNGBDBM475969(US10865208, Compound I-27 | {(2R,3S,4R,5R)-5-[4-am...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90DBRPubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))TBA
LigandPNGBDBM476025(US10865208, Compound I-82 | {(2R,3S,4R,5R)-5-[4-am...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90DBRPubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))TBA
LigandPNGBDBM476049(US10865208, Compound I-106 | [(2R,3R,4S,5R)-5-{4-a...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90DBRPubMed
TargetAurora kinase A(Mus musculus (mouse))
Takeda Pharmaceuticals International Co. , 40 Landsdowne Street, Cambridge, Massachusetts 02139, United States.

Curated by ChEMBL
LigandPNGBDBM31093(4-[[7-[2,6-bis(fluoranyl)phenyl]-9-chloranyl-5H-py...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant mouse aurora kinase A expressed in insect Sf9 cells using biotin-GLRRASLG as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
TargetAurora kinase A(Mus musculus (mouse))
Takeda Pharmaceuticals International Co. , 40 Landsdowne Street, Cambridge, Massachusetts 02139, United States.

Curated by ChEMBL
LigandPNGBDBM50097414(CHEMBL3586468)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of recombinant mouse aurora kinase A expressed in insect Sf9 cells using biotin-GLRRASLG as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8W1VPubMed
TargetAurora kinase A(Homo sapiens (Human))
Takeda Pharmaceuticals International Co. , 40 Landsdowne Street, Cambridge, Massachusetts 02139, United States.

Curated by ChEMBL
LigandPNGBDBM31093(4-[[7-[2,6-bis(fluoranyl)phenyl]-9-chloranyl-5H-py...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of Aurora A Thr288 autophosphorylation in human HeLa cells after 1 hrMore data for this Ligand-Target Pair
TargetAurora kinase A(Homo sapiens (Human))
Takeda Pharmaceuticals International Co. , 40 Landsdowne Street, Cambridge, Massachusetts 02139, United States.

Curated by ChEMBL
LigandPNGBDBM31093(4-[[7-[2,6-bis(fluoranyl)phenyl]-9-chloranyl-5H-py...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of aurora kinase A autophosphorylation at T288 in human HCT116 cells by immunofluorescence analysisMore data for this Ligand-Target Pair
TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))TBA
LigandPNGBDBM476086(US10865208, Compound I-141 | [(2R,3R,4S,5R)-5-{4-a...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90DBRPubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))TBA
LigandPNGBDBM476058(US10865208, Compound I-115 | {(2R,3R,4S,5R)-5-[4-a...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90DBRPubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))TBA
LigandPNGBDBM476042(US10865208, Compound I-99 | {(2R,3R,4S,5R)-5-[4-am...)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90DBRPubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))TBA
LigandPNGBDBM476058(US10865208, Compound I-115 | {(2R,3R,4S,5R)-5-[4-a...)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Inhibition of ATG7 in human 293HEK cells assessed as inhibition of ATG7:ATG8 thioester formation after 8 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90DBRPubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))TBA
LigandPNGBDBM476145(US10865208, Compound I-200 | {(2R,3S,5R)-5-[4-amin...)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90DBRPubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))TBA
LigandPNGBDBM476086(US10865208, Compound I-141 | [(2R,3R,4S,5R)-5-{4-a...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibition of ATG7 in human 293HEK cells assessed as inhibition of ATG7:ATG8 thioester formation after 8 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90DBRPubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))TBA
LigandPNGBDBM476117(US10865208, Compound I-172 | {(2R,3S,5R)-5-[4-amin...)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90DBRPubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))TBA
LigandPNGBDBM476084(US10865208, Compound I-139 | {(2R,3R,4S,5R)-5-[4-a...)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Inhibition of ATG7 in human 293HEK cells assessed as inhibition of ATG7:ATG8 thioester formation after 8 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90DBRPubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))TBA
LigandPNGBDBM476049(US10865208, Compound I-106 | [(2R,3R,4S,5R)-5-{4-a...)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Inhibition of ATG7 in human 293HEK cells assessed as inhibition of ATG7:ATG8 thioester formation after 8 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90DBRPubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))TBA
LigandPNGBDBM476165(US10865208, Compound I-220 | {(2S,3S,5R)-5-[4-amin...)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90DBRPubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))TBA
LigandPNGBDBM50561267(CHEMBL4754045)copy SMILES
Affinity DataIC50: 62nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90DBRPubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))TBA
LigandPNGBDBM476105(US10865208, Compound I-160 | {(2R,3S,5R)-5-[4-amin...)copy SMILEScopy InChI
Affinity DataIC50: 66nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90DBRPubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))TBA
LigandPNGBDBM476106(US10865208, Compound I-161 | US10865208, Compound ...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90DBRPubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))TBA
LigandPNGBDBM475984(US10865208, Compound I-42 | {(2R,3S,4R,5R)-5-[4-am...)copy SMILEScopy InChI
Affinity DataIC50: 83nMAssay Description:Inhibition of ATG7 in human 293HEK cells assessed as inhibition of ATG7:ATG8 thioester formation after 8 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90DBRPubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))TBA
LigandPNGBDBM50561266(CHEMBL4740719)copy SMILES
Affinity DataIC50: 84nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90DBRPubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))TBA
LigandPNGBDBM476145(US10865208, Compound I-200 | {(2R,3S,5R)-5-[4-amin...)copy SMILEScopy InChI
Affinity DataIC50: 86nMAssay Description:Inhibition of ATG7 in human 293HEK cells assessed as inhibition of ATG7:ATG8 thioester formation after 8 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90DBRPubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))TBA
LigandPNGBDBM475937(US10865208, Compound I-1 | [(2R,3S,4R,5R)-5-(4-ami...)copy SMILEScopy InChI
Affinity DataIC50: 89nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90DBRPubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))TBA
LigandPNGBDBM476150(US10865208, Compound I-205 | [(2R,3S,5R)-5-{4-amin...)copy SMILEScopy InChI
Affinity DataIC50: 95nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90DBRPubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))TBA
LigandPNGBDBM476140(US10865208, Compound I-195 | {(2R,3S,5R)-5-[4-amin...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90DBRPubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))TBA
LigandPNGBDBM476124(US10865208, Compound I-179 | [(2R,3S,5R)-5-{4-amin...)copy SMILEScopy InChI
Affinity DataIC50: 104nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90DBRPubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))TBA
LigandPNGBDBM476164(US10865208, Compound I-219 | {(2S,3S,5R)-5-[4-amin...)copy SMILEScopy InChI
Affinity DataIC50: 124nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90DBRPubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))TBA
LigandPNGBDBM476038(US10865208, Compound I-95 | {(2S,3S,4R,5R)-5-[4-am...)copy SMILEScopy InChI
Affinity DataIC50: 129nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90DBRPubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))TBA
LigandPNGBDBM476086(US10865208, Compound I-141 | [(2R,3R,4S,5R)-5-{4-a...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of ATG7 in human 293HEK cells assessed as inhibition of ATG7:ATG8 thioester formation after 4 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90DBRPubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))TBA
LigandPNGBDBM476039(US10865208, Compound I-96 | {(2S,3R,4S,5R)-5-[4-am...)copy SMILEScopy InChI
Affinity DataIC50: 145nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90DBRPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Takeda Pharmaceuticals International Co. , 40 Landsdowne Street, Cambridge, Massachusetts 02139, United States.

Curated by ChEMBL
LigandPNGBDBM50097413(CHEMBL3586473)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Binding affinity to GABAA alpha-1 benzodiazepine binding site (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8W1VPubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))TBA
LigandPNGBDBM476126(US10865208, Compound I-181 | {(2R,3S,5R)-5-[4-amin...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of ATG7 in human 293HEK cells assessed as inhibition of ATG7:ATG8 thioester formation after 8 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90DBRPubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))TBA
LigandPNGBDBM476161(US10865208, Compound I-216 | {(2S,3S,5R)-5-[4-amin...)copy SMILEScopy InChI
Affinity DataIC50: 156nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90DBRPubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))TBA
LigandPNGBDBM475993(US10865208, Compound I-51 | {(2R,3S,4R,5R)-5-[4-am...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of ATG7 in human 293HEK cells assessed as inhibition of ATG7:ATG8 thioester formation after 8 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90DBRPubMed
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