Compile Data Set for Download or QSAR
Found 627 with Last Name = 'colman' and Initial = 'pm'
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
AbbVie Inc.; The Walter and Eliza Hall Institute of Medical Research

US Patent
LigandPNGBDBM144940(US8952157, 122 | US9303025, 122)copy SMILEScopy InChI
Affinity DataKi: <0.00100nM ΔG°: <-68.5kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65G9US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
AbbVie Inc.; The Walter and Eliza Hall Institute of Medical Research

US Patent
LigandPNGBDBM145154(US8952157, 345 | US9303025, 345)copy SMILEScopy InChI
Affinity DataKi:  0.00500nM ΔG°:  -64.5kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65G9US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
AbbVie Inc.; The Walter and Eliza Hall Institute of Medical Research

US Patent
LigandPNGBDBM144855(US8952157, 37 | US9303025, 37)copy SMILEScopy InChI
Affinity DataKi:  0.00500nM ΔG°:  -64.5kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65G9US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
AbbVie Inc.; The Walter and Eliza Hall Institute of Medical Research

US Patent
LigandPNGBDBM145152(US8952157, 343 | US9303025, 343)copy SMILEScopy InChI
Affinity DataKi:  0.00900nM ΔG°:  -63.0kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65G9US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
AbbVie Inc.; The Walter and Eliza Hall Institute of Medical Research

US Patent
LigandPNGBDBM145022(US8952157, 209 | US9303025, 209)copy SMILEScopy InChI
Affinity DataKi: <0.0100nM ΔG°: <-62.8kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65G9US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
AbbVie Inc.; The Walter and Eliza Hall Institute of Medical Research

US Patent
LigandPNGBDBM145122(US8952157, 313 | US9303025, 313)copy SMILEScopy InChI
Affinity DataKi: <0.0100nM ΔG°: <-62.8kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65G9US Patent
TargetBcl-2-like protein 1(Homo sapiens (Human))
AbbVie, Inc.

Curated by ChEMBL
LigandPNGBDBM50030754(CHEMBL3342332)copy SMILEScopy InChI
Affinity DataKi: <0.0100nMAssay Description:Inhibition of BCL-XL (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0J43PubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
AbbVie, Inc.

Curated by ChEMBL
LigandPNGBDBM50030757(CHEMBL3342196)copy SMILEScopy InChI
Affinity DataKi: <0.0100nMAssay Description:Inhibition of BCL-XL (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0J43PubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
AbbVie, Inc.

Curated by ChEMBL
LigandPNGBDBM50030758(CHEMBL3342195)copy SMILEScopy InChI
Affinity DataKi: <0.0100nMAssay Description:Inhibition of BCL-XL (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0J43PubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
AbbVie, Inc.

Curated by ChEMBL
LigandPNGBDBM50030759(CHEMBL3342194)copy SMILEScopy InChI
Affinity DataKi: <0.0100nMAssay Description:Inhibition of BCL-XL (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0J43PubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
AbbVie, Inc.

Curated by ChEMBL
LigandPNGBDBM50030752(CHEMBL3342333)copy SMILEScopy InChI
Affinity DataKi:  0.0100nMAssay Description:Inhibition of BCL-XL (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0J43PubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
AbbVie Inc.; The Walter and Eliza Hall Institute of Medical Research

US Patent
LigandPNGBDBM145111(US8952157, 302 | US9303025, 302)copy SMILEScopy InChI
Affinity DataKi: <0.0100nM ΔG°: <-62.8kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65G9US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
AbbVie Inc.; The Walter and Eliza Hall Institute of Medical Research

US Patent
LigandPNGBDBM145106(US8952157, 296 | US9303025, 296)copy SMILEScopy InChI
Affinity DataKi: <0.0100nM ΔG°: <-62.8kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65G9US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
AbbVie Inc.; The Walter and Eliza Hall Institute of Medical Research

US Patent
LigandPNGBDBM145099(US8952157, 289 | US9303025, 289)copy SMILEScopy InChI
Affinity DataKi: <0.0100nM ΔG°: <-62.8kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65G9US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
AbbVie Inc.; The Walter and Eliza Hall Institute of Medical Research

US Patent
LigandPNGBDBM47135(US8952157, 297)copy SMILES
Affinity DataKi: <0.0100nM ΔG°: <-62.8kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65G9US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
AbbVie Inc.; The Walter and Eliza Hall Institute of Medical Research

US Patent
LigandPNGBDBM145208(US8952157, 399 | US9303025, 399)copy SMILEScopy InChI
Affinity DataKi: <0.0100nM ΔG°: <-62.8kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65G9US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
AbbVie Inc.; The Walter and Eliza Hall Institute of Medical Research

US Patent
LigandPNGBDBM145205(US8952157, 396 | US9303025, 396)copy SMILEScopy InChI
Affinity DataKi: <0.0100nM ΔG°: <-62.8kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65G9US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
AbbVie Inc.; The Walter and Eliza Hall Institute of Medical Research

US Patent
LigandPNGBDBM145202(US8952157, 393 | US9303025, 393)copy SMILEScopy InChI
Affinity DataKi: <0.0100nM ΔG°: <-62.8kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65G9US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
AbbVie Inc.; The Walter and Eliza Hall Institute of Medical Research

US Patent
LigandPNGBDBM145201(US8952157, 392 | US9303025, 392)copy SMILEScopy InChI
Affinity DataKi: <0.0100nM ΔG°: <-62.8kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65G9US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
AbbVie Inc.; The Walter and Eliza Hall Institute of Medical Research

US Patent
LigandPNGBDBM145200(US8952157, 391 | US9303025, 391)copy SMILEScopy InChI
Affinity DataKi: <0.0100nM ΔG°: <-62.8kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65G9US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
AbbVie Inc.; The Walter and Eliza Hall Institute of Medical Research

US Patent
LigandPNGBDBM145199(US8952157, 390 | US9303025, 390)copy SMILEScopy InChI
Affinity DataKi: <0.0100nM ΔG°: <-62.8kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65G9US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
AbbVie Inc.; The Walter and Eliza Hall Institute of Medical Research

US Patent
LigandPNGBDBM145198(US8952157, 389 | US9303025, 389)copy SMILEScopy InChI
Affinity DataKi: <0.0100nM ΔG°: <-62.8kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65G9US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
AbbVie Inc.; The Walter and Eliza Hall Institute of Medical Research

US Patent
LigandPNGBDBM145196(US8952157, 387 | US9303025, 387)copy SMILEScopy InChI
Affinity DataKi: <0.0100nM ΔG°: <-62.8kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65G9US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
AbbVie Inc.; The Walter and Eliza Hall Institute of Medical Research

US Patent
LigandPNGBDBM145195(US8952157, 386)copy SMILEScopy InChI
Affinity DataKi: <0.0100nM ΔG°: <-62.8kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65G9US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
AbbVie Inc.; The Walter and Eliza Hall Institute of Medical Research

US Patent
LigandPNGBDBM145187(US8952157, 378 | US9303025, 378)copy SMILEScopy InChI
Affinity DataKi: <0.0100nM ΔG°: <-62.8kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65G9US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
AbbVie Inc.; The Walter and Eliza Hall Institute of Medical Research

US Patent
LigandPNGBDBM145180(US8952157, 371 | US9303025, 371)copy SMILEScopy InChI
Affinity DataKi: <0.0100nM ΔG°: <-62.8kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65G9US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
AbbVie Inc.; The Walter and Eliza Hall Institute of Medical Research

US Patent
LigandPNGBDBM145011(US8952157, 198 | US9303025, 198)copy SMILEScopy InChI
Affinity DataKi: <0.0100nM ΔG°: <-62.8kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65G9US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
AbbVie Inc.; The Walter and Eliza Hall Institute of Medical Research

US Patent
LigandPNGBDBM145014(US8952157, 201 | US9303025, 201)copy SMILEScopy InChI
Affinity DataKi:  0.0100nM ΔG°:  -62.8kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65G9US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
AbbVie Inc.; The Walter and Eliza Hall Institute of Medical Research

US Patent
LigandPNGBDBM145219(US8952157, 410 | US9303025, 410)copy SMILEScopy InChI
Affinity DataKi: <0.0100nM ΔG°: <-62.8kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65G9US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
AbbVie Inc.; The Walter and Eliza Hall Institute of Medical Research

US Patent
LigandPNGBDBM145127(US8952157, 318 | US9303025, 318)copy SMILEScopy InChI
Affinity DataKi: <0.0100nM ΔG°: <-62.8kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65G9US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
AbbVie Inc.; The Walter and Eliza Hall Institute of Medical Research

US Patent
LigandPNGBDBM145133(US8952157, 324 | US9303025, 324)copy SMILEScopy InChI
Affinity DataKi: <0.0100nM ΔG°: <-62.8kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65G9US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
AbbVie Inc.; The Walter and Eliza Hall Institute of Medical Research

US Patent
LigandPNGBDBM145139(US8952157, 330 | US9303025, 330)copy SMILEScopy InChI
Affinity DataKi: <0.0100nM ΔG°: <-62.8kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65G9US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
AbbVie Inc.; The Walter and Eliza Hall Institute of Medical Research

US Patent
LigandPNGBDBM145144(US8952157, 335 | US9303025, 335)copy SMILEScopy InChI
Affinity DataKi: <0.0100nM ΔG°: <-62.8kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65G9US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
AbbVie Inc.; The Walter and Eliza Hall Institute of Medical Research

US Patent
LigandPNGBDBM145145(US8952157, 336 | US9303025, 336)copy SMILEScopy InChI
Affinity DataKi: <0.0100nM ΔG°: <-62.8kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65G9US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
AbbVie Inc.; The Walter and Eliza Hall Institute of Medical Research

US Patent
LigandPNGBDBM145147(US8952157, 338 | US9303025, 338)copy SMILEScopy InChI
Affinity DataKi: <0.0100nM ΔG°: <-62.8kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65G9US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
AbbVie Inc.; The Walter and Eliza Hall Institute of Medical Research

US Patent
LigandPNGBDBM145155(US8952157, 346 | US9303025, 346)copy SMILEScopy InChI
Affinity DataKi: <0.0100nM ΔG°: <-62.8kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65G9US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
AbbVie Inc.; The Walter and Eliza Hall Institute of Medical Research

US Patent
LigandPNGBDBM145159(US8952157, 350 | US9303025, 350)copy SMILEScopy InChI
Affinity DataKi: <0.0100nM ΔG°: <-62.8kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65G9US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
AbbVie Inc.; The Walter and Eliza Hall Institute of Medical Research

US Patent
LigandPNGBDBM145172(US8952157, 363 | US9303025, 363)copy SMILEScopy InChI
Affinity DataKi: <0.0100nM ΔG°: <-62.8kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65G9US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
AbbVie Inc.; The Walter and Eliza Hall Institute of Medical Research

US Patent
LigandPNGBDBM145177(US8952157, 368 | US9303025, 368)copy SMILEScopy InChI
Affinity DataKi: <0.0100nM ΔG°: <-62.8kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65G9US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
AbbVie Inc.; The Walter and Eliza Hall Institute of Medical Research

US Patent
LigandPNGBDBM145179(US8952157, 370 | US9303025, 370)copy SMILEScopy InChI
Affinity DataKi: <0.0100nM ΔG°: <-62.8kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65G9US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
AbbVie Inc.; The Walter and Eliza Hall Institute of Medical Research

US Patent
LigandPNGBDBM145176(US8952157, 367 | US9303025, 367)copy SMILEScopy InChI
Affinity DataKi:  0.0120nM ΔG°:  -62.3kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65G9US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
AbbVie Inc.; The Walter and Eliza Hall Institute of Medical Research

US Patent
LigandPNGBDBM144970(US8952157, 154 | US9303025, 154)copy SMILEScopy InChI
Affinity DataKi:  0.0120nM ΔG°:  -62.3kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65G9US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
AbbVie Inc.; The Walter and Eliza Hall Institute of Medical Research

US Patent
LigandPNGBDBM144856(US8952157, 38 | US9303025, 38)copy SMILEScopy InChI
Affinity DataKi:  0.0130nM ΔG°:  -62.1kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65G9US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
AbbVie Inc.; The Walter and Eliza Hall Institute of Medical Research

US Patent
LigandPNGBDBM145173(US8952157, 364 | US9303025, 364)copy SMILEScopy InChI
Affinity DataKi:  0.0140nM ΔG°:  -62.0kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65G9US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
AbbVie Inc.; The Walter and Eliza Hall Institute of Medical Research

US Patent
LigandPNGBDBM145178(US8952157, 369 | US9303025, 369)copy SMILEScopy InChI
Affinity DataKi:  0.0140nM ΔG°:  -62.0kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65G9US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
AbbVie Inc.; The Walter and Eliza Hall Institute of Medical Research

US Patent
LigandPNGBDBM145170(US8952157, 361 | US9303025, 361)copy SMILEScopy InChI
Affinity DataKi:  0.0150nM ΔG°:  -61.8kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65G9US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
AbbVie Inc.; The Walter and Eliza Hall Institute of Medical Research

US Patent
LigandPNGBDBM144956(US8952157, 138)copy SMILEScopy InChI
Affinity DataKi:  0.0160nM ΔG°:  -61.6kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65G9US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
AbbVie Inc.; The Walter and Eliza Hall Institute of Medical Research

US Patent
LigandPNGBDBM145162(US8952157, 353 | US9303025, 353)copy SMILEScopy InChI
Affinity DataKi:  0.0160nM ΔG°:  -61.6kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65G9US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
AbbVie Inc.; The Walter and Eliza Hall Institute of Medical Research

US Patent
LigandPNGBDBM145150(US8952157, 341 | US9303025, 341)copy SMILEScopy InChI
Affinity DataKi:  0.0170nM ΔG°:  -61.5kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65G9US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
AbbVie Inc.; The Walter and Eliza Hall Institute of Medical Research

US Patent
LigandPNGBDBM145098(US8952157, 288 | US9303025, 288)copy SMILEScopy InChI
Affinity DataKi:  0.0170nM ΔG°:  -61.5kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65G9US Patent
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