Compile Data Set for Download or QSAR
Found 102 with Last Name = 'wovkulich' and Initial = 'pm'
TargetTyrosine-protein kinase SYK [360-635](Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM227529(US9334278, I-18)copy SMILEScopy InChI
Affinity DataIC50: 2nMT: 2°CAssay Description:Assay plates: 96-well MultiScreen 0.65 μm filter plates (Millipore Cat. No.: MADVNOB 10) Streptavidin coated beads: Streptavidin Sepharose™,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JD4VN3US Patent
TargetTyrosine-protein kinase SYK [360-635](Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM227523(US9334278, I-12)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMT: 2°CAssay Description:Assay plates: 96-well MultiScreen 0.65 μm filter plates (Millipore Cat. No.: MADVNOB 10) Streptavidin coated beads: Streptavidin Sepharose™,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JD4VN3US Patent
TargetTyrosine-protein kinase SYK [360-635](Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM227549(US9334278, I-37)copy SMILEScopy InChI
Affinity DataIC50: 4.80nMT: 2°CAssay Description:Assay plates: 96-well MultiScreen 0.65 μm filter plates (Millipore Cat. No.: MADVNOB 10) Streptavidin coated beads: Streptavidin Sepharose™,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JD4VN3US Patent
TargetTyrosine-protein kinase SYK [360-635](Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM227537(US9334278, I-26)copy SMILEScopy InChI
Affinity DataIC50: 5.60nMT: 2°CAssay Description:Assay plates: 96-well MultiScreen 0.65 μm filter plates (Millipore Cat. No.: MADVNOB 10) Streptavidin coated beads: Streptavidin Sepharose™,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JD4VN3US Patent
TargetTyrosine-protein kinase SYK [360-635](Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM227535(US9334278, I-24)copy SMILES
Affinity DataIC50: 5.90nMT: 2°CAssay Description:Assay plates: 96-well MultiScreen 0.65 μm filter plates (Millipore Cat. No.: MADVNOB 10) Streptavidin coated beads: Streptavidin Sepharose™,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JD4VN3US Patent
TargetTyrosine-protein kinase SYK [360-635](Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM227512(US9334278, I-1)copy SMILEScopy InChI
Affinity DataIC50: 8.5nMT: 2°CAssay Description:Assay plates: 96-well MultiScreen 0.65 μm filter plates (Millipore Cat. No.: MADVNOB 10) Streptavidin coated beads: Streptavidin Sepharose™,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JD4VN3US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM291171(US9580411, Example 86)copy SMILEScopy InChI
Affinity DataIC50: 9nMT: 2°CAssay Description:IC50s (effective concentration) of compounds on the human TRPA1 channel were determined using a Hamamatsu FDSS fluorescence plate reader. CHO cells e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25T3NJMUS Patent
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50328264(5-(2-chlorophenyl)-3-isopropyl-7-nitro-2,10-dihydr...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1X42PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50426474(CHEMBL1980391)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2902541PubMed
TargetTyrosine-protein kinase SYK [360-635](Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM227522(US9334278, I-11)copy SMILEScopy InChI
Affinity DataIC50: 10.9nMT: 2°CAssay Description:Assay plates: 96-well MultiScreen 0.65 μm filter plates (Millipore Cat. No.: MADVNOB 10) Streptavidin coated beads: Streptavidin Sepharose™,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JD4VN3US Patent
TargetTyrosine-protein kinase SYK [360-635](Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM227524(US9334278, I-13)copy SMILEScopy InChI
Affinity DataIC50: 12.8nMT: 2°CAssay Description:Assay plates: 96-well MultiScreen 0.65 μm filter plates (Millipore Cat. No.: MADVNOB 10) Streptavidin coated beads: Streptavidin Sepharose™,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JD4VN3US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM291170(2-[N-(Propan-2-yl)(4-fluorobenzene)sulfonamido]-N-...)copy SMILEScopy InChI
Affinity DataIC50: 13nMT: 2°CAssay Description:IC50s (effective concentration) of compounds on the human TRPA1 channel were determined using a Hamamatsu FDSS fluorescence plate reader. CHO cells e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25T3NJMUS Patent
TargetTyrosine-protein kinase SYK [360-635](Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM227516(US9334278, I-5)copy SMILEScopy InChI
Affinity DataIC50: 13.7nMT: 2°CAssay Description:Assay plates: 96-well MultiScreen 0.65 μm filter plates (Millipore Cat. No.: MADVNOB 10) Streptavidin coated beads: Streptavidin Sepharose™,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JD4VN3US Patent
TargetTyrosine-protein kinase SYK [360-635](Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM227520(US9334278, I-9)copy SMILEScopy InChI
Affinity DataIC50: 15.5nMT: 2°CAssay Description:Assay plates: 96-well MultiScreen 0.65 μm filter plates (Millipore Cat. No.: MADVNOB 10) Streptavidin coated beads: Streptavidin Sepharose™,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JD4VN3US Patent
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50328256(5-(2-fluorophenyl)-2,10-dihydrobenzo[e]pyrazolo[4,...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1X42PubMed
TargetTyrosine-protein kinase SYK [360-635](Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM227521(US9334278, I-10)copy SMILEScopy InChI
Affinity DataIC50: 16.3nMT: 2°CAssay Description:Assay plates: 96-well MultiScreen 0.65 μm filter plates (Millipore Cat. No.: MADVNOB 10) Streptavidin coated beads: Streptavidin Sepharose™,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JD4VN3US Patent
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50328279(5-(2-fluorophenyl)-2,10-dihydrobenzo[e]pyrazolo[4,...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1X42PubMed
TargetTyrosine-protein kinase SYK [360-635](Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM227517(US9334278, I-6)copy SMILEScopy InChI
Affinity DataIC50: 17.1nMT: 2°CAssay Description:Assay plates: 96-well MultiScreen 0.65 μm filter plates (Millipore Cat. No.: MADVNOB 10) Streptavidin coated beads: Streptavidin Sepharose™,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JD4VN3US Patent
TargetTyrosine-protein kinase SYK [360-635](Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM227542(US9334278, I-31)copy SMILEScopy InChI
Affinity DataIC50: 17.8nMT: 2°CAssay Description:Assay plates: 96-well MultiScreen 0.65 μm filter plates (Millipore Cat. No.: MADVNOB 10) Streptavidin coated beads: Streptavidin Sepharose™,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JD4VN3US Patent
TargetTyrosine-protein kinase SYK [360-635](Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM227538(US9334278, I-27)copy SMILES
Affinity DataIC50: 18.8nMT: 2°CAssay Description:Assay plates: 96-well MultiScreen 0.65 μm filter plates (Millipore Cat. No.: MADVNOB 10) Streptavidin coated beads: Streptavidin Sepharose™,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JD4VN3US Patent
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50328267(5-(2-chlorophenyl)-7-nitro-3-(1H-pyrrol-2-yl)-2,10...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1X42PubMed
TargetTyrosine-protein kinase SYK [360-635](Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM227514(US9334278, I-3)copy SMILEScopy InChI
Affinity DataIC50: 21.1nMT: 2°CAssay Description:Assay plates: 96-well MultiScreen 0.65 μm filter plates (Millipore Cat. No.: MADVNOB 10) Streptavidin coated beads: Streptavidin Sepharose™,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JD4VN3US Patent
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50426474(CHEMBL1980391)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of CHK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2902541PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50328280(CHEMBL1258022 | N-(5-(2-chlorophenyl)-2,10-dihydro...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1X42PubMed
TargetTyrosine-protein kinase SYK [360-635](Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM227533(US9334278, I-22)copy SMILEScopy InChI
Affinity DataIC50: 25.1nMT: 2°CAssay Description:Assay plates: 96-well MultiScreen 0.65 μm filter plates (Millipore Cat. No.: MADVNOB 10) Streptavidin coated beads: Streptavidin Sepharose™,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JD4VN3US Patent
TargetTyrosine-protein kinase SYK [360-635](Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM227513(US9334278, I-2)copy SMILEScopy InChI
Affinity DataIC50: 27.4nMT: 2°CAssay Description:Assay plates: 96-well MultiScreen 0.65 μm filter plates (Millipore Cat. No.: MADVNOB 10) Streptavidin coated beads: Streptavidin Sepharose™,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JD4VN3US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50426474(CHEMBL1980391)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of FGFR1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2902541PubMed
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM291169(1-(4-Fluoro-N-isopropylphenylsulfonamido)-N-((6-(6...)copy SMILEScopy InChI
Affinity DataIC50: 29nMT: 2°CAssay Description:IC50s (effective concentration) of compounds on the human TRPA1 channel were determined using a Hamamatsu FDSS fluorescence plate reader. CHO cells e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25T3NJMUS Patent
TargetTyrosine-protein kinase SYK [360-635](Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM227531(US9334278, I-20)copy SMILEScopy InChI
Affinity DataIC50: 30nMT: 2°CAssay Description:Assay plates: 96-well MultiScreen 0.65 μm filter plates (Millipore Cat. No.: MADVNOB 10) Streptavidin coated beads: Streptavidin Sepharose™,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JD4VN3US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50328258(CHEMBL1257912 | N-(5-(2-chlorophenyl)-2,10-dihydro...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1X42PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50426473(CHEMBL2322701)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2902541PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50328257(5-(2-chlorophenyl)-2,10-dihydrobenzo[e]pyrazolo[4,...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1X42PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50328255(5-(2-chlorophenyl)-3-methyl-7-nitro-2,10-dihydrobe...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1X42PubMed
TargetTyrosine-protein kinase SYK [360-635](Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM227525(US9334278, I-14)copy SMILEScopy InChI
Affinity DataIC50: 35.9nMT: 2°CAssay Description:Assay plates: 96-well MultiScreen 0.65 μm filter plates (Millipore Cat. No.: MADVNOB 10) Streptavidin coated beads: Streptavidin Sepharose™,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JD4VN3US Patent
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50328258(CHEMBL1257912 | N-(5-(2-chlorophenyl)-2,10-dihydro...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1X42PubMed
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM291163(US9580411, Example 79-(R) | US9580411, Example 79-...)copy SMILEScopy InChI
Affinity DataIC50: 38nMT: 2°CAssay Description:IC50s (effective concentration) of compounds on the human TRPA1 channel were determined using a Hamamatsu FDSS fluorescence plate reader. CHO cells e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25T3NJMUS Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50328256(5-(2-fluorophenyl)-2,10-dihydrobenzo[e]pyrazolo[4,...)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1X42PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50328274(7-fluoro-5-(2-fluorophenyl)-3-methyl-2,10-dihydrob...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1X42PubMed
TargetTyrosine-protein kinase SYK [360-635](Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM227515(US9334278, I-4)copy SMILEScopy InChI
Affinity DataIC50: 42.8nMT: 2°CAssay Description:Assay plates: 96-well MultiScreen 0.65 μm filter plates (Millipore Cat. No.: MADVNOB 10) Streptavidin coated beads: Streptavidin Sepharose™,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JD4VN3US Patent
TargetTyrosine-protein kinase SYK [360-635](Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM227543(US9334278, I-32)copy SMILEScopy InChI
Affinity DataIC50: 43.7nMT: 2°CAssay Description:Assay plates: 96-well MultiScreen 0.65 μm filter plates (Millipore Cat. No.: MADVNOB 10) Streptavidin coated beads: Streptavidin Sepharose™,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JD4VN3US Patent
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50328281(CHEMBL1258141 | N'-[5-(2-chlorophenyl)-2,10-dihydr...)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1X42PubMed
TargetTyrosine-protein kinase SYK [360-635](Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM227528(US9334278, I-17)copy SMILEScopy InChI
Affinity DataIC50: 49.9nMT: 2°CAssay Description:Assay plates: 96-well MultiScreen 0.65 μm filter plates (Millipore Cat. No.: MADVNOB 10) Streptavidin coated beads: Streptavidin Sepharose™,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JD4VN3US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50426473(CHEMBL2322701)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of FGFR1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2902541PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50328269(5-(2-chlorophenyl)-7-nitro-3-(pyridin-4-yl)-2,10-d...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1X42PubMed
TargetTyrosine-protein kinase SYK [360-635](Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM227519(US9334278, I-8)copy SMILEScopy InChI
Affinity DataIC50: 51.3nMT: 2°CAssay Description:Assay plates: 96-well MultiScreen 0.65 μm filter plates (Millipore Cat. No.: MADVNOB 10) Streptavidin coated beads: Streptavidin Sepharose™,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JD4VN3US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM291163(US9580411, Example 79-(R) | US9580411, Example 79-...)copy SMILEScopy InChI
Affinity DataIC50: 55nMT: 2°CAssay Description:IC50s (effective concentration) of compounds on the human TRPA1 channel were determined using a Hamamatsu FDSS fluorescence plate reader. CHO cells e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25T3NJMUS Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM291168(2,2-Dideuterio-2-(4-fluoro-N-isopropylphenylsulfon...)copy SMILEScopy InChI
Affinity DataIC50: 58nMT: 2°CAssay Description:IC50s (effective concentration) of compounds on the human TRPA1 channel were determined using a Hamamatsu FDSS fluorescence plate reader. CHO cells e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25T3NJMUS Patent
TargetAurora kinase A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50426474(CHEMBL1980391)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:Inhibition of aurora-A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2902541PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50328272(5-(2-fluorophenyl)-3-methyl-2,10-dihydrobenzo[e]py...)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1X42PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50328260(5-(2-chlorophenyl)-7-nitro-2,10-dihydrobenzo[e]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1X42PubMed
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