Compile Data Set for Download or QSAR
Found 384 with Last Name = 'mortenson' and Initial = 'pn'
TargetTrans-sialidase(Trypanosoma cruzi)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50118216((4-formyl-5-hydroxy-6-methylpyridin-3-yl)methyl di...)copy SMILEScopy InChI
Affinity DataKi:  7.30E+6nMAssay Description:Inhibition of Trypanosoma cruzi trans-SialidaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92C7JPubMed
TargetTrans-sialidase(Trypanosoma cruzi)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM4706((2R,3R,4S)-3-acetamido-4-hydroxy-2-[(1R,2R)-1,2,3-...)copy SMILEScopy InChI
Affinity DataKi:  1.23E+7nMAssay Description:Inhibition of Trypanosoma cruzi trans-SialidaseMore data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
Frontier Medicines

Curated by ChEMBL
LigandPNGBDBM50520331(CHEMBL4445137)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human N-myristoyltransferase assessed as reduction in CoASH production by fluorogenic detection based assayMore data for this Ligand-Target Pair
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Frontier Medicines

Curated by ChEMBL
LigandPNGBDBM50520335(CHEMBL4465173)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of beta2 adrenoreceptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6WM7PubMed
TargetDiscoidin domain-containing receptor 2(Homo sapiens (Human))
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of DDR2 (unknown origin) after 1 hr by time resolved fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ925GPubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Frontier Medicines

Curated by ChEMBL
LigandPNGBDBM50520336(CHEMBL4470042)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human PDE10A2 using cAMP substrate by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6WM7PubMed
TargetCyclin-dependent kinase 4(Oryctolagus cuniculus (Rabbit))
Astex Therapeutics Ltd.; Novartis AG

US Patent
LigandPNGBDBM50420304(CHEMBL2089065 | US8598217, 165)copy SMILEScopy InChI
Affinity DataIC50: 3nMpH: 7.5Assay Description:A 384-well microtiter Lance TR-FRET (time-resolved-fluorescence energy transfer) endpoint assay was used for CDK4/cyclin D1 kinase activity measureme...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BG2MN8US Patent
TargetDiscoidin domain-containing receptor 2(Homo sapiens (Human))
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50112617(CHEMBL3608786)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Inhibition of DDR2 (unknown origin) after 1 hr by time resolved fluorescence methodMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4(Oryctolagus cuniculus (Rabbit))
Astex Therapeutics Ltd.; Novartis AG

US Patent
LigandPNGBDBM107751(CHEMBL2089063 | US8598217, 89)copy SMILEScopy InChI
Affinity DataIC50: 4nMpH: 7.5Assay Description:A 384-well microtiter Lance TR-FRET (time-resolved-fluorescence energy transfer) endpoint assay was used for CDK4/cyclin D1 kinase activity measureme...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BG2MN8US Patent
TargetCyclin-dependent kinase 4(Oryctolagus cuniculus (Rabbit))
Astex Therapeutics Ltd.; Novartis AG

US Patent
LigandPNGBDBM107755(US8598217, 140)copy SMILEScopy InChI
Affinity DataIC50: 4nMpH: 7.5Assay Description:A 384-well microtiter Lance TR-FRET (time-resolved-fluorescence energy transfer) endpoint assay was used for CDK4/cyclin D1 kinase activity measureme...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BG2MN8US Patent
TargetDiscoidin domain-containing receptor 2(Homo sapiens (Human))
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50112628(CHEMBL3608789)copy SMILEScopy InChI
Affinity DataIC50: 4.5nMAssay Description:Inhibition of DDR2 (unknown origin) after 1 hr by time resolved fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ925GPubMed
TargetCyclin-dependent kinase 4(Oryctolagus cuniculus (Rabbit))
Astex Therapeutics Ltd.; Novartis AG

US Patent
LigandPNGBDBM107761(US8598217, 174)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 7.5Assay Description:A 384-well microtiter Lance TR-FRET (time-resolved-fluorescence energy transfer) endpoint assay was used for CDK4/cyclin D1 kinase activity measureme...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BG2MN8US Patent
TargetDiscoidin domain-containing receptor 2(Homo sapiens (Human))
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50112631(CHEMBL3608790)copy SMILEScopy InChI
Affinity DataIC50: 5.80nMAssay Description:Inhibition of DDR2 (unknown origin) after 1 hr by time resolved fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ925GPubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50576323(CHEMBL4866146)copy SMILES
Affinity DataIC50: 6nMAssay Description:Inhibition of human HPGDS assessed as reduction in PGD2 formation using PGH2 as substrate by mass spectrometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B28047PubMed
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50112618(CHEMBL3608787)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of DDR1 (unknown origin) after 1 hr by time resolved fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ925GPubMed
TargetDiscoidin domain-containing receptor 2(Homo sapiens (Human))
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50112634(CHEMBL3608791)copy SMILEScopy InChI
Affinity DataIC50: 6.10nMAssay Description:Inhibition of DDR2 (unknown origin) after 1 hr by time resolved fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ925GPubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50576316(CHEMBL4870703)copy SMILES
Affinity DataIC50: 8nMAssay Description:Inhibition of human HPGDS assessed as reduction in PGD2 formation using PGH2 as substrate by mass spectrometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B28047PubMed
TargetCyclin-dependent kinase 4(Oryctolagus cuniculus (Rabbit))
Astex Therapeutics Ltd.; Novartis AG

US Patent
LigandPNGBDBM107765(US8598217, 166)copy SMILEScopy InChI
Affinity DataIC50: 8nMpH: 7.5Assay Description:A 384-well microtiter Lance TR-FRET (time-resolved-fluorescence energy transfer) endpoint assay was used for CDK4/cyclin D1 kinase activity measureme...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BG2MN8US Patent
TargetDiscoidin domain-containing receptor 2(Homo sapiens (Human))
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50112618(CHEMBL3608787)copy SMILEScopy InChI
Affinity DataIC50: 8.10nMAssay Description:Inhibition of DDR2 (unknown origin) after 1 hr by time resolved fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ925GPubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50526494(CHEMBL4439454)copy SMILEScopy InChI
Affinity DataIC50: 8.20nMAssay Description:Inhibition of full-length human His6-tagged HPGDS expressed in Escherichia coli BL21 (DE3) using PGH2 as substrate measured after 90 to 120 secs by R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3R00PubMed
TargetDiscoidin domain-containing receptor 2(Homo sapiens (Human))
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50112615(CHEMBL3608785)copy SMILEScopy InChI
Affinity DataIC50: 8.20nMAssay Description:Inhibition of DDR2 (unknown origin) after 1 hr by time resolved fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ925GPubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50576314(CHEMBL4864805)copy SMILES
Affinity DataIC50: 9nMAssay Description:Inhibition of human HPGDS assessed as reduction in PGD2 formation using PGH2 as substrate by mass spectrometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50526495(CHEMBL4452633)copy SMILEScopy InChI
Affinity DataIC50: 9.70nMAssay Description:Inhibition of full-length human His6-tagged HPGDS expressed in Escherichia coli BL21 (DE3) using PGH2 as substrate measured after 90 to 120 secs by R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3R00PubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50112615(CHEMBL3608785)copy SMILEScopy InChI
Affinity DataIC50: 9.80nMAssay Description:Inhibition of c-Kit (unknown origin) using biotinylated HER2 peptide as substrate by time resolved fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ925GPubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50526485(CHEMBL4473072)copy SMILEScopy InChI
Affinity DataIC50: 9.90nMAssay Description:Inhibition of full-length human His6-tagged HPGDS expressed in Escherichia coli BL21 (DE3) using PGH2 as substrate measured after 90 to 120 secs by R...More data for this Ligand-Target Pair
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50576324(CHEMBL4868339)copy SMILES
Affinity DataIC50: 10nMAssay Description:Inhibition of human HPGDS assessed as reduction in PGD2 formation using PGH2 as substrate by mass spectrometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B28047PubMed
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