Compile Data Set for Download or QSAR
Found 57 with Last Name = 'waid' and Initial = 'pp'
TargetLanosterol synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50003025(1-((4aS,5S,6S,8aS)-6-Hydroxy-5,8a-dimethyl-octahyd...)copy SMILEScopy InChI
Affinity DataKi:  28nMAssay Description:Inhibitory concentration of the compound against purified rat liver Oxidosqualene cyclase (OSC)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1C83
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6736(1,7-Annulated indolocarbazole deriv. 16c | 7-(pyrr...)copy SMILEScopy InChI
Affinity DataIC50: 50nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6740(1,7-Annulated indolocarbazole deriv. 16g | 7-(pipe...)copy SMILEScopy InChI
Affinity DataIC50: 65nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6735(1,7-Annulated indolocarbazole deriv. 16b | 7-(azet...)copy SMILEScopy InChI
Affinity DataIC50: 75nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6738(1,7-Annulated indolocarbazole deriv. 16e | 7-(morp...)copy SMILEScopy InChI
Affinity DataIC50: 75nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6741(1,7-Annulated indolocarbazole deriv. 16h | 7-(1,4-...)copy SMILEScopy InChI
Affinity DataIC50: 79nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6737(1,7-Annulated indolocarbazole deriv. 16d | 7-(pipe...)copy SMILEScopy InChI
Affinity DataIC50: 87nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6729(1,7-Annulated indolocarbazole deriv. 6l | 7-bromo-...)copy SMILEScopy InChI
Affinity DataIC50: 90nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6739(1,7-Annulated indolocarbazole deriv. 16f | 7-(thio...)copy SMILEScopy InChI
Affinity DataIC50: 90nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6720(1,4,14-triazaheptacyclo[16.8.1.0^{2,17}.0^{3,11}.0...)copy SMILEScopy InChI
Affinity DataIC50: 94nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetLanosterol synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50003025(1-((4aS,5S,6S,8aS)-6-Hydroxy-5,8a-dimethyl-octahyd...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration against purified rat liver Oxidosqualene cyclase (OSC)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1C83
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6728(1,7-Annulated indolocarbazole deriv. 6k | 7-chloro...)copy SMILEScopy InChI
Affinity DataIC50: 110nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetLanosterol synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50003025(1-((4aS,5S,6S,8aS)-6-Hydroxy-5,8a-dimethyl-octahyd...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibitory activity against Oxidosqualene-lanosterol cyclase enzyme obtained from rat liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24T6H9NPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6719(1,4,14-triazaheptacyclo[16.7.1.0^{2,17}.0^{3,11}.0...)copy SMILEScopy InChI
Affinity DataIC50: 110nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6721(1,4,14-triazaheptacyclo[16.9.1.0^{2,17}.0^{3,11}.0...)copy SMILEScopy InChI
Affinity DataIC50: 120nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6732(1,7-Annulated indolocarbazole deriv. 6o | 7-(pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 160nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6734(1,7-Annulated indolocarbazole deriv. 16a | 7-(amin...)copy SMILEScopy InChI
Affinity DataIC50: 170nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetLanosterol synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50003026(1-(6-Hydroxy-5,8a-dimethyl-octahydro-isoquinolin-2...)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Inhibitory activity against Oxidosqualene-lanosterol cyclase enzyme obtained from rat liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24T6H9NPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6718(1,4,14-triazaheptacyclo[16.6.1.0^{2,17}.0^{3,11}.0...)copy SMILEScopy InChI
Affinity DataIC50: 240nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6730(1,7-Annulated indolocarbazole deriv. 6m | 7-(trifl...)copy SMILEScopy InChI
Affinity DataIC50: 290nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetLanosterol synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281884(2-(1-Dodecyl-piperidin-4-yl)-propan-1-ol | CHEMBL1...)copy SMILEScopy InChI
Affinity DataIC50: 420nMAssay Description:Inhibitory concentration against purified rat liver Oxidosqualene cyclase (OSC)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1C83
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6727(1,7-Annulated indolocarbazole deriv. 6j | 7-fluoro...)copy SMILEScopy InChI
Affinity DataIC50: 420nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetLanosterol synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50003032((4aS,5S,6S,8aS)-2-Dodecyl-5,8a-dimethyl-decahydro-...)copy SMILEScopy InChI
Affinity DataIC50: 550nMAssay Description:Inhibitory activity against Oxidosqualene-lanosterol cyclase enzyme obtained from rat liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24T6H9NPubMed
TargetLanosterol synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50003032((4aS,5S,6S,8aS)-2-Dodecyl-5,8a-dimethyl-decahydro-...)copy SMILEScopy InChI
Affinity DataIC50: 550nMAssay Description:Inhibitory concentration against purified rat liver Oxidosqualene cyclase (OSC)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1C83
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6733(1,7-Annulated indolocarbazole deriv. 6p | 7-(pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 590nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6720(1,4,14-triazaheptacyclo[16.8.1.0^{2,17}.0^{3,11}.0...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6719(1,4,14-triazaheptacyclo[16.7.1.0^{2,17}.0^{3,11}.0...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6729(1,7-Annulated indolocarbazole deriv. 6l | 7-bromo-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetLanosterol synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281889(1-(1,5,9-Trimethyl-decyl)-piperidine | CHEMBL41817...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibitory concentration against purified rat liver Oxidosqualene cyclase (OSC)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1C83
TargetLanosterol synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281895(1-(1,5,9-Trimethyl-decyl)-piperidin-4-ol | CHEMBL1...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory concentration against purified rat liver Oxidosqualene cyclase (OSC)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1C83
TargetLanosterol synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50003027((4aS,5S,6S,8aS)-5,8a-Dimethyl-2-(1,5,9-trimethyl-d...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory activity against Oxidosqualene-lanosterol cyclase enzyme obtained from rat liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24T6H9NPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6730(1,7-Annulated indolocarbazole deriv. 6m | 7-(trifl...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6728(1,7-Annulated indolocarbazole deriv. 6k | 7-chloro...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6727(1,7-Annulated indolocarbazole deriv. 6j | 7-fluoro...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6721(1,4,14-triazaheptacyclo[16.9.1.0^{2,17}.0^{3,11}.0...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6718(1,4,14-triazaheptacyclo[16.6.1.0^{2,17}.0^{3,11}.0...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6722(1,7-Annulated indolocarbazole deriv. 6e | 9-fluoro...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6723(1,7-Annulated indolocarbazole deriv. 6f | 7,8-difl...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6724(1,7-Annulated indolocarbazole deriv. 6g | 8-fluoro...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6725(1,7-Annulated indolocarbazole deriv. 6h | 8-bromo-...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6726(1,7-Annulated indolocarbazole deriv. 6i | methyl 1...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6731(1,7-Annulated indolocarbazole deriv. 6n | methyl 1...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetLanosterol synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50003027((4aS,5S,6S,8aS)-5,8a-Dimethyl-2-(1,5,9-trimethyl-d...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory concentration against purified rat liver Oxidosqualene cyclase (OSC)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1C83
TargetLanosterol synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281888(2-[1-(1,5,9-Trimethyl-decyl)-piperidin-4-yl]-propa...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory concentration against purified rat liver Oxidosqualene cyclase (OSC)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1C83
TargetLanosterol synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281893((4aS,5S,6S,8aS)-5,8a-Dimethyl-2-((E)-1,5,9-trimeth...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory concentration against purified rat liver Oxidosqualene cyclase (OSC)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1C83
TargetLanosterol synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281886(1-(1,5,9-Trimethyl-decyl)-piperidin-3-ol | CHEMBL1...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory concentration against purified rat liver Oxidosqualene cyclase (OSC)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1C83
TargetLanosterol synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281885(1-Dodecyl-piperidin-3-ol | CHEMBL17348)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory concentration against purified rat liver Oxidosqualene cyclase (OSC)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1C83
TargetLanosterol synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50003030((2S,4aS,8aR)-1,1,4a-Trimethyl-decahydro-naphthalen...)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibitory activity against Oxidosqualene-lanosterol cyclase enzyme obtained from rat liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24T6H9NPubMed
TargetLanosterol synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281891(1-Dodecyl-piperidin-4-ol | CHEMBL17729)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibitory concentration against purified rat liver Oxidosqualene cyclase (OSC)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1C83
TargetLanosterol synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281887(1-((E)-1,5,9-Trimethyl-deca-4,8-dienyl)-piperidin-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against purified rat liver Oxidosqualene cyclase (OSC)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1C83
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