Compile Data Set for Download or QSAR
Found 26 with Last Name = 'das' and Initial = 'pr'
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292438(1,-(4-amino-5-oxotridecane-1,13-diyl)diguanidine |...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Displacement of QNB from muscarinic M2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2GS1PubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292438(1,-(4-amino-5-oxotridecane-1,13-diyl)diguanidine |...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Displacement of QNB from muscarinic M1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2GS1PubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292438(1,-(4-amino-5-oxotridecane-1,13-diyl)diguanidine |...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Displacement of QNB from muscarinic M4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2GS1PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50197834(2,9-dihydroxy-1-methoxydibenzo[cd,f]indol-4(5H)-on...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ664XPubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50197834(2,9-dihydroxy-1-methoxydibenzo[cd,f]indol-4(5H)-on...)copy SMILEScopy InChI
Affinity DataIC50: 214nMAssay Description:Inhibition of CDC2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ664XPubMed
TargetGenome polyprotein(Hepatitis C virus)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50135740(2,3,4,5,6,7,14,15-octahydroxy-13-(5-hydroxy-4-oxo-...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibitory activity of the compound evaluated in the HCV NS3 protease activity assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HX1C2DPubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50070315((3S,9S)-9-Benzyl-3-isobutyl-6-methyl-13-(1-methyl-...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Compound was evaluated for inhibitory activity against cholesteryl ester transfer proteinMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25X282FPubMed
TargetGenome polyprotein(Hepatitis C virus)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50135739(13-[3,5-dihydroxy-4-(3-phenylpropanoyl)phenoxy]-2,...)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Inhibitory activity of the compound evaluated in the HCV NS3 protease assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HX1C2DPubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292439(CHEMBL479224 | N-(1,13-diguanidino-5-oxotridecan-4...)copy SMILEScopy InChI
Affinity DataIC50: 910nMAssay Description:Displacement of QNB from muscarinic M4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2GS1PubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292439(CHEMBL479224 | N-(1,13-diguanidino-5-oxotridecan-4...)copy SMILEScopy InChI
Affinity DataIC50: 960nMAssay Description:Displacement of QNB from muscarinic M2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2GS1PubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292439(CHEMBL479224 | N-(1,13-diguanidino-5-oxotridecan-4...)copy SMILEScopy InChI
Affinity DataIC50: 1.41E+3nMAssay Description:Displacement of QNB from muscarinic M1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2GS1PubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50197834(2,9-dihydroxy-1-methoxydibenzo[cd,f]indol-4(5H)-on...)copy SMILEScopy InChI
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ664XPubMed
TargetAurora kinase B(Homo sapiens (Human))
Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50197834(2,9-dihydroxy-1-methoxydibenzo[cd,f]indol-4(5H)-on...)copy SMILEScopy InChI
Affinity DataIC50: 2.14E+3nMAssay Description:Inhibition of Aurora 2 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ664XPubMed
TargetGenome polyprotein(Human rhinovirus B)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50135740(2,3,4,5,6,7,14,15-octahydroxy-13-(5-hydroxy-4-oxo-...)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibitory activity of the compound evaluated in the HCV protease binding assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HX1C2DPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50153762(3-(4-Methoxy-phenyl)-acrylic acid 2-{(1S,2S)-2-[(S...)copy SMILEScopy InChI
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of MIP-1beta ligand of chemokine receptor 5 induced calcium signal in U-87-CCR5 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1K31PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50153762(3-(4-Methoxy-phenyl)-acrylic acid 2-{(1S,2S)-2-[(S...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of MIP-1beta ligand of chemokine receptor 5 induced calcium signal in U-87-CCR5 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1K31PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50153764((Z)-1-((1S,2S)-2-((S)-hydroxy((R)-6-oxo-3,6-dihydr...)copy SMILEScopy InChI
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of MIP-1beta ligand of chemokine receptor 5 induced calcium signal in U-87-CCR5 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1K31PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50153762(3-(4-Methoxy-phenyl)-acrylic acid 2-{(1S,2S)-2-[(S...)copy SMILEScopy InChI
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of 50% of RANTES co-receptor of chemokine receptor 5 induced calcium signal in U-87-CCR5 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1K31PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50153762(3-(4-Methoxy-phenyl)-acrylic acid 2-{(1S,2S)-2-[(S...)copy SMILEScopy InChI
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of MIP-1alpha ligand of chemokine receptor 5 induced calcium signal in U-87-CCR5 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1K31PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50153762(3-(4-Methoxy-phenyl)-acrylic acid 2-{(1S,2S)-2-[(S...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of RANTES co-receptor of chemokine receptor 5 induced calcium signal in U-87-CCR5 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1K31PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50153764((Z)-1-((1S,2S)-2-((S)-hydroxy((R)-6-oxo-3,6-dihydr...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MIP-1alpha ligand of chemokine receptor 5 induced calcium signal in U-87-CCR5 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1K31PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50153762(3-(4-Methoxy-phenyl)-acrylic acid 2-{(1S,2S)-2-[(S...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MIP-1alpha ligand of chemokine receptor 5 induced calcium signal in U-87-CCR5 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1K31PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50153764((Z)-1-((1S,2S)-2-((S)-hydroxy((R)-6-oxo-3,6-dihydr...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of RANTES co-receptor of chemokine receptor 5 induced calcium signal in U-87-CCR5 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1K31PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50306911(8-((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-hydroxymeth...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ664XPubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50070315((3S,9S)-9-Benzyl-3-isobutyl-6-methyl-13-(1-methyl-...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMAssay Description:Tested for inhibition of substrate hydrolysis in the presence of porcine kidney esterase at a concentration of 45 nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25X282FPubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50070315((3S,9S)-9-Benzyl-3-isobutyl-6-methyl-13-(1-methyl-...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:pA2 value towards endothelin receptor A was determined as functional ETA antagonismMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25X282FPubMed