Compile Data Set for Download or QSAR
Found 134 with Last Name = 'ortiz de montellano' and Initial = 'pr'
TargetCytochrome P450 4A4(Oryctolagus cuniculus)
University of California

Curated by ChEMBL
LigandPNGBDBM50047304(12-Hydroxy-heptadec-16-ynoic acid | CHEMBL33390)copy SMILEScopy InChI
Affinity DataKi:  1.80E+3nMAssay Description:Inactivation of prostaglandin E1 omega-hydroxylase (Cytochrome P450 4A4) in rabbit lungMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52NQWPubMed
TargetCytochrome P450 4A4(Oryctolagus cuniculus)
University of California

Curated by ChEMBL
LigandPNGBDBM50047307(12-Hydroxy-heptadec-16-ynoic acid | CHEMBL33875)copy SMILEScopy InChI
Affinity DataKi:  3.60E+3nMAssay Description:Inactivation of prostaglandin E1 omega-hydroxylase (Cytochrome P450 4A4) in rabbit lungMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52NQWPubMed
TargetCytochrome P450 4A4(Oryctolagus cuniculus)
University of California

Curated by ChEMBL
LigandPNGBDBM50047305(12-Hydroxy-heptadec-16-ynoic acid | CHEMBL29370)copy SMILEScopy InChI
Affinity DataKi:  4.80E+3nMAssay Description:Inactivation of prostaglandin E1 omega-hydroxylase (Cytochrome P450 4A4) in rabbit lungMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52NQWPubMed
TargetCytochrome P450 4A4(Oryctolagus cuniculus)
University of California

Curated by ChEMBL
LigandPNGBDBM50047306(12-Hydroxy-2,2-dimethyl-heptadec-16-ynoic acid | C...)copy SMILEScopy InChI
Affinity DataKi:  4.90E+3nMAssay Description:Inactivation of prostaglandin E1 omega-hydroxylase (Cytochrome P450 4A4) in rabbit lungMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52NQWPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Incyte Corporation

LigandPNGBDBM25795(1-benzoyl-4-(9H-fluoren-9-yl)piperazine | piperazi...)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:The assay measured the NADH-dependent catalysis of an octenoyl-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M92VHPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Incyte Corporation

LigandPNGBDBM15709(1-Cyclohexyl-N-(3,5-diphenyl-4-hydroxyl)phenyl-5-o...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:The assay measured the NADH-dependent catalysis of an octenoyl-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2707ZP0PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Incyte Corporation

LigandPNGBDBM25796(5-{[4-(9H-fluoren-9-yl)piperazin-1-yl]carbonyl}-1H...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:The assay measured the NADH-dependent catalysis of an octenoyl-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to ...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Incyte Corporation

LigandPNGBDBM15712(N-((Anthracen-9-yl)methyl)-1-cyclooctyl-N-methyl-5...)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:The assay measured the NADH-dependent catalysis of an octenoyl-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2707ZP0PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Incyte Corporation

LigandPNGBDBM15711(1-Cycloheptyl-N-(3,5-diphenyl-4-hydroxyl)phenyl-5-...)copy SMILEScopy InChI
Affinity DataIC50: 360nMAssay Description:The assay measured the NADH-dependent catalysis of an octenoyl-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2707ZP0PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Incyte Corporation

LigandPNGBDBM15677(1-cyclohexyl-N-(3,5-dichlorophenyl)-5-oxopyrrolidi...)copy SMILEScopy InChI
Affinity DataIC50: 390nMAssay Description:The assay measured the NADH-dependent catalysis of an octenoyl-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to ...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Incyte Corporation

LigandPNGBDBM15685(1-Cyclohexyl-N-(3-phenylphenyl)-5-oxopyrrolidine-3...)copy SMILEScopy InChI
Affinity DataIC50: 390nMAssay Description:The assay measured the NADH-dependent catalysis of an octenoyl-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2707ZP0PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Incyte Corporation

LigandPNGBDBM25794(1-(9H-fluoren-9-yl)-4-[(4-methylphenyl)carbonyl]pi...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:The assay measured the NADH-dependent catalysis of an octenoyl-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M92VHPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Incyte Corporation

LigandPNGBDBM15686(N-(3-benzylphenyl)-1-cyclohexyl-5-oxopyrrolidine-3...)copy SMILEScopy InChI
Affinity DataIC50: 410nMAssay Description:The assay measured the NADH-dependent catalysis of an octenoyl-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2707ZP0PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Incyte Corporation

LigandPNGBDBM15708(N-((Anthracen-9-yl)methyl)-1-(bicyclo[2.2.1]heptan...)copy SMILEScopy InChI
Affinity DataIC50: 460nMAssay Description:The assay measured the NADH-dependent catalysis of an octenoyl-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2707ZP0PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Incyte Corporation

LigandPNGBDBM15710(N-((Anthracen-9-yl)methyl)-1-cycloheptyl-N-methyl-...)copy SMILEScopy InChI
Affinity DataIC50: 620nMAssay Description:The assay measured the NADH-dependent catalysis of an octenoyl-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2707ZP0PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Incyte Corporation

LigandPNGBDBM15687(N-((Anthracen-9-yl)methyl)-1-cyclohexyl-N-methyl-5...)copy SMILEScopy InChI
Affinity DataIC50: 750nMAssay Description:The assay measured the NADH-dependent catalysis of an octenoyl-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2707ZP0PubMed
TargetCamphor 5-monooxygenase(Pseudomonas putida)
University of California

Curated by ChEMBL
LigandPNGBDBM50149348(1-(2-Ethyl-butyl)-1H-imidazole | CHEMBL330775)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Inhibition of wild type cytochrome P450cam expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20R9NVPPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Incyte Corporation

LigandPNGBDBM15707(1-(Bicyclo[2.2.1]heptan-2-yl)-5-oxo-N-(3-phenylphe...)copy SMILEScopy InChI
Affinity DataIC50: 845nMAssay Description:The assay measured the NADH-dependent catalysis of an octenoyl-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2707ZP0PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Incyte Corporation

LigandPNGBDBM15678(N-(3-Bromo-5-(trifluoromethyl)phenyl)-1-cyclohexyl...)copy SMILEScopy InChI
Affinity DataIC50: 850nMAssay Description:The assay measured the NADH-dependent catalysis of an octenoyl-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2707ZP0PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Incyte Corporation

LigandPNGBDBM15651(N-(3-bromophenyl)-1-cyclohexyl-5-oxopyrrolidine-3-...)copy SMILEScopy InChI
Affinity DataIC50: 890nMpH: 6.8 T: 2°CAssay Description:The assay measured the NADH-dependent catalysis of an octenoyl-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to ...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Incyte Corporation

LigandPNGBDBM15669(N-(5-chloro-2-methylphenyl)-1-cyclohexyl-5-oxopyrr...)copy SMILEScopy InChI
Affinity DataIC50: 970nMAssay Description:The assay measured the NADH-dependent catalysis of an octenoyl-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to ...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Incyte Corporation

LigandPNGBDBM25778(1-(3-chlorophenyl)-4-[(3,4-dimethylphenyl)carbonyl...)copy SMILEScopy InChI
Affinity DataIC50: 990nMpH: 6.8 T: 2°CAssay Description:The assay measured the NADH-dependent catalysis of an octenoyl-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M92VHPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Incyte Corporation

LigandPNGBDBM25797(5-({4-[bis(4-fluorophenyl)methyl]piperazin-1-yl}ca...)copy SMILEScopy InChI
Affinity DataIC50: 1.04E+3nMAssay Description:The assay measured the NADH-dependent catalysis of an octenoyl-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M92VHPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Incyte Corporation

LigandPNGBDBM15713(1-Cyclooctyl-N-(3,5-diphenyl-4-hydroxyl)phenyl-5-o...)copy SMILEScopy InChI
Affinity DataIC50: 1.29E+3nMAssay Description:The assay measured the NADH-dependent catalysis of an octenoyl-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2707ZP0PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Incyte Corporation

LigandPNGBDBM15679(1-Cyclohexyl-N-(3-(trifluoromethyl)-5-methoxypheny...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:The assay measured the NADH-dependent catalysis of an octenoyl-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2707ZP0PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Incyte Corporation

LigandPNGBDBM15653(N-(3-chlorophenyl)-1-cyclohexyl-5-oxopyrrolidine-3...)copy SMILEScopy InChI
Affinity DataIC50: 1.35E+3nMpH: 6.8 T: 2°CAssay Description:The assay measured the NADH-dependent catalysis of an octenoyl-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2707ZP0PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Incyte Corporation

LigandPNGBDBM15688(1-Cyclohexyl-N-(9H-fluoren-1-yl)-5-oxopyrrolidine-...)copy SMILEScopy InChI
Affinity DataIC50: 1.39E+3nMAssay Description:The assay measured the NADH-dependent catalysis of an octenoyl-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2707ZP0PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Incyte Corporation

LigandPNGBDBM15676(1-Cyclohexyl-N-(3,5-difluorophenyl)-5-oxopyrrolidi...)copy SMILEScopy InChI
Affinity DataIC50: 1.49E+3nMAssay Description:The assay measured the NADH-dependent catalysis of an octenoyl-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2707ZP0PubMed
TargetCamphor 5-monooxygenase(Pseudomonas putida)
University of California

Curated by ChEMBL
LigandPNGBDBM50149352(1-Cyclohexylmethyl-1H-imidazole | CHEMBL120057)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of wild type cytochrome P450cam expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20R9NVPPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Incyte Corporation

LigandPNGBDBM15681(N-(5-chloro-2-methoxyphenyl)-1-cyclohexyl-5-oxopyr...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:The assay measured the NADH-dependent catalysis of an octenoyl-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2707ZP0PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Incyte Corporation

LigandPNGBDBM25779(1-[(3,4-dimethylphenyl)carbonyl]-4-[3-(trifluorome...)copy SMILEScopy InChI
Affinity DataIC50: 1.85E+3nMpH: 6.8 T: 2°CAssay Description:The assay measured the NADH-dependent catalysis of an octenoyl-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M92VHPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Incyte Corporation

LigandPNGBDBM25798(1-[bis(4-fluorophenyl)methyl]-4-[(4-methylphenyl)c...)copy SMILEScopy InChI
Affinity DataIC50: 1.89E+3nMAssay Description:The assay measured the NADH-dependent catalysis of an octenoyl-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M92VHPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Incyte Corporation

LigandPNGBDBM25799(1-benzoyl-4-[bis(4-fluorophenyl)methyl]piperazine ...)copy SMILEScopy InChI
Affinity DataIC50: 2.04E+3nMAssay Description:The assay measured the NADH-dependent catalysis of an octenoyl-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M92VHPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Incyte Corporation

LigandPNGBDBM15691(1-Cyclohexyl-N-(9-ethyl-9H-carbazol-3-yl)-5-oxopyr...)copy SMILEScopy InChI
Affinity DataIC50: 2.57E+3nMAssay Description:The assay measured the NADH-dependent catalysis of an octenoyl-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2707ZP0PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Incyte Corporation

LigandPNGBDBM25775(1-(3-chlorophenyl)-4-[(4-methylphenyl)carbonyl]pip...)copy SMILEScopy InChI
Affinity DataIC50: 3.07E+3nMpH: 6.8 T: 2°CAssay Description:The assay measured the NADH-dependent catalysis of an octenoyl-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M92VHPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Incyte Corporation

LigandPNGBDBM15673(1-cyclohexyl-N-(3,5-dimethylphenyl)-5-oxopyrrolidi...)copy SMILEScopy InChI
Affinity DataIC50: 3.14E+3nMAssay Description:The assay measured the NADH-dependent catalysis of an octenoyl-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2707ZP0PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Incyte Corporation

LigandPNGBDBM15689(N-(3-(Benzyloxy)phenyl)-1-cyclohexyl-5-oxopyrrolid...)copy SMILEScopy InChI
Affinity DataIC50: 3.39E+3nMAssay Description:The assay measured the NADH-dependent catalysis of an octenoyl-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2707ZP0PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Incyte Corporation

LigandPNGBDBM15658(1-cyclohexyl-5-oxo-N-[3-(trifluoromethyl)phenyl]py...)copy SMILEScopy InChI
Affinity DataIC50: 3.51E+3nMpH: 6.8 T: 2°CAssay Description:The assay measured the NADH-dependent catalysis of an octenoyl-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2707ZP0PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Incyte Corporation

LigandPNGBDBM15680(N-(3,5-Bis(trifluoromethyl)phenyl)-1-cyclohexyl-5-...)copy SMILEScopy InChI
Affinity DataIC50: 3.67E+3nMAssay Description:The assay measured the NADH-dependent catalysis of an octenoyl-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2707ZP0PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Incyte Corporation

LigandPNGBDBM15695(N-(3-chlorophenyl)-5-oxo-1-phenylpyrrolidine-3-car...)copy SMILEScopy InChI
Affinity DataIC50: 3.94E+3nMAssay Description:The assay measured the NADH-dependent catalysis of an octenoyl-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2707ZP0PubMed
TargetCamphor 5-monooxygenase(Pseudomonas putida)
University of California

Curated by ChEMBL
LigandPNGBDBM50149347(1-Cyclopropylmethyl-1H-imidazole | 1-Subsituted 1H...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of wild type cytochrome P450cam expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20R9NVPPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Incyte Corporation

LigandPNGBDBM15690(1-Cyclohexyl-4-(1-(phenyl(4-chlorophenyl)methyl)pi...)copy SMILEScopy InChI
Affinity DataIC50: 4.47E+3nMAssay Description:The assay measured the NADH-dependent catalysis of an octenoyl-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2707ZP0PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Incyte Corporation

LigandPNGBDBM25792(4-benzyl-1-[(4-methylphenyl)carbonyl]piperidine | ...)copy SMILEScopy InChI
Affinity DataIC50: 5.16E+3nMpH: 6.8 T: 2°CAssay Description:The assay measured the NADH-dependent catalysis of an octenoyl-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to ...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Incyte Corporation

LigandPNGBDBM15692(1-Cyclohexyl-4-(1-(phenyl(p-tolyl)methyl)piperazin...)copy SMILEScopy InChI
Affinity DataIC50: 5.18E+3nMAssay Description:The assay measured the NADH-dependent catalysis of an octenoyl-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2707ZP0PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Incyte Corporation

LigandPNGBDBM15694(4-(1-(Bis(4-fluorophenyl)methyl)piperazine-4-carbo...)copy SMILEScopy InChI
Affinity DataIC50: 5.51E+3nMAssay Description:The assay measured the NADH-dependent catalysis of an octenoyl-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2707ZP0PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Incyte Corporation

LigandPNGBDBM15661(1-cyclohexyl-N-[3-(2-methylpropyl)phenyl]-5-oxopyr...)copy SMILEScopy InChI
Affinity DataIC50: 5.55E+3nMpH: 6.8 T: 2°CAssay Description:The assay measured the NADH-dependent catalysis of an octenoyl-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2707ZP0PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Incyte Corporation

LigandPNGBDBM25787(1-(3-chlorophenyl)-4-[(3,4-dichlorophenyl)carbonyl...)copy SMILEScopy InChI
Affinity DataIC50: 6.05E+3nMpH: 6.8 T: 2°CAssay Description:The assay measured the NADH-dependent catalysis of an octenoyl-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M92VHPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Incyte Corporation

LigandPNGBDBM25774(1-[(4-methylphenyl)carbonyl]-4-[3-(trifluoromethyl...)copy SMILEScopy InChI
Affinity DataIC50: 6.26E+3nMpH: 6.8 T: 2°CAssay Description:The assay measured the NADH-dependent catalysis of an octenoyl-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M92VHPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Incyte Corporation

LigandPNGBDBM15693(1-Cyclohexyl-4-(1-((4-fluorophenyl)(phenyl)methyl)...)copy SMILEScopy InChI
Affinity DataIC50: 6.41E+3nMAssay Description:The assay measured the NADH-dependent catalysis of an octenoyl-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2707ZP0PubMed
TargetCamphor 5-monooxygenase(Pseudomonas putida)
University of California

Curated by ChEMBL
LigandPNGBDBM50149354(1-cyclopentyl-5-propyl-1H-imidazole | CHEMBL120774)copy SMILEScopy InChI
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of L244A mutant cytochrome P450cam expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20R9NVPPubMed
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