Compile Data Set for Download or QSAR
Found 67 with Last Name = 'bernhardt' and Initial = 'pv'
TargetNACHT, LRR and PYD domains-containing protein 3(Mus musculus)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50155926(CHEMBL3183703)copy SMILEScopy InChI
Affinity DataIC50: 7.5nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-stimulated mouse BMDM assessed as reduction in NLRP3 inflammasome-induced IL-1beta production prei...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7XKVPubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal de Pernambuco

Curated by ChEMBL
LigandPNGBDBM50058809(CHEMBL3329524)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-Phe-Argaminomethylcoumarin as fluorogenic substrate preincubated for 10 mins before subst...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W097M2PubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal de Pernambuco

Curated by ChEMBL
LigandPNGBDBM50058806(CHEMBL3329519)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-Phe-Argaminomethylcoumarin as fluorogenic substrate preincubated for 10 mins before subst...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W097M2PubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)copy SMILEScopy InChI
Affinity DataIC50: 67nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition measured for 5 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC92HZPubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition measured for 5 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC92HZPubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50199870(CHEMBL3904593)copy SMILEScopy InChI
Affinity DataIC50: 232nMAssay Description:Inhibition of NLRP3 inflammasome in LPS-stimulated human monocyte derived macrophages assessed as reduction in NLRP3 inflammasome-induced IL-1beta pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7XKVPubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal de Pernambuco

Curated by ChEMBL
LigandPNGBDBM50058805(CHEMBL3329518)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-Phe-Argaminomethylcoumarin as fluorogenic substrate preincubated for 10 mins before subst...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W097M2PubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50537903(CHEMBL4639635)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Reversal of P-gp mediated multidrug resistance in human SW620/AD300 cells assessed as potentiation of doxorubicin-induced antiproliferative activity ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4T65PubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal de Pernambuco

Curated by ChEMBL
LigandPNGBDBM50058808(CHEMBL3329521)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-Phe-Argaminomethylcoumarin as fluorogenic substrate preincubated for 10 mins before subst...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W097M2PubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal de Pernambuco

Curated by ChEMBL
LigandPNGBDBM50058804(CHEMBL3329515)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-Phe-Argaminomethylcoumarin as fluorogenic substrate preincubated for 10 mins before subst...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W097M2PubMed
LigandPNGBDBM50600678(CHEMBL5176174)copy SMILES
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9997NPubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM81939(CAS_52-53-9 | NSC_62969 | VERAPAMIL)copy SMILEScopy InChI
Affinity DataIC50: 710nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4PVZPubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM81939(CAS_52-53-9 | NSC_62969 | VERAPAMIL)copy SMILEScopy InChI
Affinity DataIC50: 810nMAssay Description:Reversal of P-gp mediated multidrug resistance in human SW620/AD300 cells assessed as potentiation of doxorubicin-induced antiproliferative activity ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4T65PubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50537908(CHEMBL4641108)copy SMILEScopy InChI
Affinity DataIC50: 820nMAssay Description:Reversal of P-gp mediated multidrug resistance in human SW620/AD300 cells assessed as potentiation of doxorubicin-induced antiproliferative activity ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4T65PubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50537904(CHEMBL4646781)copy SMILEScopy InChI
Affinity DataIC50: 880nMAssay Description:Reversal of P-gp mediated multidrug resistance in human SW620/AD300 cells assessed as potentiation of doxorubicin-induced antiproliferative activity ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4T65PubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50596547(CHEMBL5193426)copy SMILES
Affinity DataIC50: 1.01E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4PVZPubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50277455(CHEMBL4175281)copy SMILEScopy InChI
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition measured for 5 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC92HZPubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50277454(CHEMBL4168083)copy SMILEScopy InChI
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition measured for 5 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC92HZPubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50277463(CHEMBL4163526)copy SMILEScopy InChI
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition measured for 5 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC92HZPubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50277461(CHEMBL4164649)copy SMILEScopy InChI
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition measured for 5 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC92HZPubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50277451(CHEMBL4160164)copy SMILEScopy InChI
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition measured for 5 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC92HZPubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50277452(CHEMBL4162052)copy SMILEScopy InChI
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition measured for 5 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC92HZPubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50537907(CHEMBL4636390)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Reversal of P-gp mediated multidrug resistance in human SW620/AD300 cells assessed as potentiation of doxorubicin-induced antiproliferative activity ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4T65PubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50596546(CHEMBL5194241)copy SMILES
Affinity DataIC50: 1.20E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4PVZPubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50277462(CHEMBL4171426)copy SMILEScopy InChI
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition measured for 5 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC92HZPubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50199858(CHEMBL3956814)copy SMILEScopy InChI
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of NLRP3 inflammasome in LPS-stimulated human monocyte derived macrophages assessed as reduction in NLRP3 inflammasome-induced IL-1beta pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7XKVPubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal de Pernambuco

Curated by ChEMBL
LigandPNGBDBM50058802(CHEMBL3329513)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-Phe-Argaminomethylcoumarin as fluorogenic substrate preincubated for 10 mins before subst...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W097M2PubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal de Pernambuco

Curated by ChEMBL
LigandPNGBDBM50058803(CHEMBL2409542)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-Phe-Argaminomethylcoumarin as fluorogenic substrate preincubated for 10 mins before subst...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W097M2PubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50596548(CHEMBL5205284)copy SMILES
Affinity DataIC50: 1.44E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4PVZPubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50596549(CHEMBL5175965)copy SMILES
Affinity DataIC50: 1.48E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4PVZPubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50596544(CHEMBL5204503)copy SMILES
Affinity DataIC50: 1.53E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4PVZPubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50199871(CHEMBL3920126)copy SMILEScopy InChI
Affinity DataIC50: 1.83E+3nMAssay Description:Inhibition of NLRP3 inflammasome in LPS-stimulated human monocyte derived macrophages assessed as reduction in NLRP3 inflammasome-induced IL-1beta pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7XKVPubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50199869(CHEMBL3929254)copy SMILEScopy InChI
Affinity DataIC50: 1.97E+3nMAssay Description:Inhibition of NLRP3 inflammasome in LPS-stimulated human monocyte derived macrophages assessed as reduction in NLRP3 inflammasome-induced IL-1beta pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7XKVPubMed
LigandPNGBDBM50600667(CHEMBL5180164)copy SMILES
Affinity DataIC50: 2.70E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9997NPubMed
LigandPNGBDBM50600670(CHEMBL5204687)copy SMILES
Affinity DataIC50: 3.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9997NPubMed
LigandPNGBDBM50600662(CHEMBL5193721)copy SMILES
Affinity DataIC50: 3.10E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9997NPubMed
LigandPNGBDBM50600671(CHEMBL5175684)copy SMILES
Affinity DataIC50: 3.70E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9997NPubMed
LigandPNGBDBM50600666(CHEMBL5178722)copy SMILES
Affinity DataIC50: 4.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9997NPubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50596550(CHEMBL5171374)copy SMILES
Affinity DataIC50: 4.49E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4PVZPubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal de Pernambuco

Curated by ChEMBL
LigandPNGBDBM50058807(CHEMBL3329520)copy SMILEScopy InChI
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-Phe-Argaminomethylcoumarin as fluorogenic substrate preincubated for 10 mins before subst...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W097M2PubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50277453(CHEMBL4174866)copy SMILEScopy InChI
Affinity DataIC50: 4.93E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition measured for 5 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC92HZPubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50596551(CHEMBL5171189)copy SMILES
Affinity DataIC50: 5.04E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4PVZPubMed
LigandPNGBDBM50600660(CHEMBL5187573)copy SMILES
Affinity DataIC50: 5.70E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9997NPubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM22984((8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-me...)copy SMILEScopy InChI
Affinity DataIC50: 5.75E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4PVZPubMed
LigandPNGBDBM50600664(CHEMBL5185601)copy SMILES
Affinity DataIC50: 6.20E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9997NPubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50199868(CHEMBL3906283)copy SMILEScopy InChI
Affinity DataIC50: 6.35E+3nMAssay Description:Inhibition of NLRP3 inflammasome in LPS-stimulated human monocyte derived macrophages assessed as reduction in NLRP3 inflammasome-induced IL-1beta pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7XKVPubMed
LigandPNGBDBM50600661(CHEMBL5180114)copy SMILES
Affinity DataIC50: 7.30E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9997NPubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50596545(CHEMBL5170888)copy SMILES
Affinity DataIC50: 7.58E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4PVZPubMed
LigandPNGBDBM50600665(CHEMBL5192274)copy SMILES
Affinity DataIC50: 8.90E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9997NPubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal de Pernambuco

Curated by ChEMBL
LigandPNGBDBM50058801(CHEMBL3329506)copy SMILEScopy InChI
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-Phe-Argaminomethylcoumarin as fluorogenic substrate preincubated for 10 mins before subst...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W097M2PubMed
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