Compile Data Set for Download or QSAR
Found 149 with Last Name = 'iversen' and Initial = 'pw'
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50150699(3-(9-fluoro-2-(piperidine-1-carbonyl)-1,2,3,4-tetr...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of Glycogen synthase kinase-3 beta dependent Tau protein serine-396 phosphorylation in human SY5Y cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56KG1PubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318884(CHEMBL1084546 | CHEMBL2430359 | N-methyl-N-(3-((2-...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of PTK2 (unknown origin)More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50150699(3-(9-fluoro-2-(piperidine-1-carbonyl)-1,2,3,4-tetr...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human Glycogen synthase kinase-3 betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56KG1PubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50150700(7-(4-Imidazo[1,2-a]pyridin-3-yl-2,5-dioxo-2,5-dihy...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human Glycogen synthase kinase-3 betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56KG1PubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50150698(3-(imidazo[1,2-a]pyridin-3-yl)-4-(2-(morpholine-4-...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human Glycogen synthase kinase-3 betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56KG1PubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50150701(7-(4-(H-imidazo[1,2-a]pyridin-3-yl)-2,5-dioxo-2,5-...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human Glycogen synthase kinase-3 betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56KG1PubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50150702(3-Imidazo[1,2-a]pyridin-3-yl-4-[2-(piperidine-1-ca...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of Glycogen synthase kinase-3 beta dependent Tau protein serine-396 phosphorylation in human SY5Y cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56KG1PubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50150702(3-Imidazo[1,2-a]pyridin-3-yl-4-[2-(piperidine-1-ca...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human Glycogen synthase kinase-3 betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56KG1PubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of PDGFRA (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44RQCPubMedDrugBank
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50150698(3-(imidazo[1,2-a]pyridin-3-yl)-4-(2-(morpholine-4-...)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Inhibition of Glycogen synthase kinase-3 beta dependent Tau protein serine-396 phosphorylation in human SY5Y cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56KG1PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of CSF1R (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44RQCPubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM31085(1-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluorom...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44RQCPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50150697(3-Imidazo[1,2-a]pyridin-3-yl-4-[9-methyl-2-(piperi...)copy SMILEScopy InChI
Affinity DataIC50: 5.20nMAssay Description:Inhibition of human Glycogen synthase kinase-3 betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56KG1PubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM12985(5-Amido-pyrrolopyrazole 9d | CHEMBL402548 | N-{5-[...)copy SMILEScopy InChI
Affinity DataIC50: 7.90nMAssay Description:Inhibition of ABL1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44RQCPubMed
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50439561(CHEMBL1965660 | US9670191, F26)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44RQCPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50150701(7-(4-(H-imidazo[1,2-a]pyridin-3-yl)-2,5-dioxo-2,5-...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of Glycogen synthase kinase-3 beta dependent Tau protein serine-396 phosphorylation in human SY5Y cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56KG1PubMed
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM6866(1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3b ...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of CDK5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44RQCPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50150700(7-(4-Imidazo[1,2-a]pyridin-3-yl-2,5-dioxo-2,5-dihy...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of Glycogen synthase kinase-3 beta dependent Tau protein serine-396 phosphorylation in human SY5Y cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56KG1PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277583(2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44RQCPubMed
TargetAurora kinase A(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of AURKA (unknown origin)More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50150697(3-Imidazo[1,2-a]pyridin-3-yl-4-[9-methyl-2-(piperi...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of Glycogen synthase kinase-3 beta dependent Tau protein serine-396 phosphorylation in human SY5Y cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56KG1PubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50396934(CHEMBL2001019 | CHEMBL2170804 | US9062045, Compara...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of MET (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM33971(AEB071 | Sotrastaurin | med.21724, Compound 190)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of PIM1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44RQCPubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM482158(BDBM50242742 | TAE684)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of CSF1R (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44RQCPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50059889((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Inhibition of human Glycogen synthase kinase-3 betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56KG1PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM6309(6-Acetyl-8-cyclopentyl-5-methyl-2-(5-piperazin-1-y...)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44RQCPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM26300(2-{3-[(7-{3-[ethyl(2-hydroxyethyl)amino]propoxy}qu...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44RQCPubMed
TargetAurora kinase A(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277545(4-(9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-benzo[...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of AURKA (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44RQCPubMed
TargetMAP kinase-activated protein kinase 5(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM30185(CHEMBL226403 | Pyrrolopyridine, 16)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of MAPKAPK5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44RQCPubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly and Company

Curated by ChEMBL
LigandPNGBDBM50475107(CHEMBL179928)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR50W8PubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly and Company

Curated by ChEMBL
LigandPNGBDBM50475105(CHEMBL189605)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR50W8PubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly and Company

Curated by ChEMBL
LigandPNGBDBM50475147(CHEMBL185804)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR50W8PubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly and Company

Curated by ChEMBL
LigandPNGBDBM50475152(CHEMBL188975)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR50W8PubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly and Company

Curated by ChEMBL
LigandPNGBDBM50475104(CHEMBL362085)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR50W8PubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly and Company

Curated by ChEMBL
LigandPNGBDBM50475145(CHEMBL187453)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR50W8PubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly and Company

Curated by ChEMBL
LigandPNGBDBM50475139(CHEMBL187192)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR50W8PubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly and Company

Curated by ChEMBL
LigandPNGBDBM50475159(CHEMBL189864)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR50W8PubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly and Company

Curated by ChEMBL
LigandPNGBDBM50475146(CHEMBL189138)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR50W8PubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly and Company

Curated by ChEMBL
LigandPNGBDBM50475122(CHEMBL188715)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR50W8PubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly and Company

Curated by ChEMBL
LigandPNGBDBM50475124(CHEMBL188687)copy SMILEScopy InChI
Affinity DataIC50: 360nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR50W8PubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50150697(3-Imidazo[1,2-a]pyridin-3-yl-4-[9-methyl-2-(piperi...)copy SMILEScopy InChI
Affinity DataIC50: 370nMAssay Description:Inhibition of human Protein kinase C beta 2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56KG1PubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly and Company

Curated by ChEMBL
LigandPNGBDBM50475109(CHEMBL185679)copy SMILEScopy InChI
Affinity DataIC50: 410nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR50W8PubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly and Company

Curated by ChEMBL
LigandPNGBDBM50475121(CHEMBL363735)copy SMILEScopy InChI
Affinity DataIC50: 410nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR50W8PubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50150699(3-(9-fluoro-2-(piperidine-1-carbonyl)-1,2,3,4-tetr...)copy SMILEScopy InChI
Affinity DataIC50: 420nMAssay Description:Inhibition of human Protein kinase C beta 2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56KG1PubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly and Company

Curated by ChEMBL
LigandPNGBDBM50475154(CHEMBL187967)copy SMILEScopy InChI
Affinity DataIC50: 440nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR50W8PubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly and Company

Curated by ChEMBL
LigandPNGBDBM50475108(CHEMBL180882)copy SMILEScopy InChI
Affinity DataIC50: 460nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR50W8PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM30192(Pyrrolopyridine, 23)copy SMILEScopy InChI
Affinity DataIC50: 501nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44RQCPubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly and Company

Curated by ChEMBL
LigandPNGBDBM50475134(CHEMBL181855)copy SMILEScopy InChI
Affinity DataIC50: 530nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR50W8PubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly and Company

Curated by ChEMBL
LigandPNGBDBM50475131(CHEMBL364656)copy SMILEScopy InChI
Affinity DataIC50: 530nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR50W8PubMed
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