Compile Data Set for Download or QSAR
Found 185 with Last Name = 'renard' and Initial = 'py'
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50556952(CHEMBL4754487)copy SMILES
Affinity DataKi:  0.680nMAssay Description:Mixed-type inhibition of recombinant human AChE assessed as inhibition constant using acetylthiocholine iodide as substrate by Cornish-Bowden plot an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K077XJPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50556952(CHEMBL4754487)copy SMILES
Affinity DataKi:  0.940nMAssay Description:Mixed-type inhibition of recombinant human AChE assessed as dissociation constant for protein-substrate-compound complex using acetylthiocholine iodi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K077XJPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50556952(CHEMBL4754487)copy SMILES
Affinity DataIC50: 0.770nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K077XJPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50523281(CHEMBL4583650)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human recombinant AChE using ATCh as substrate preincubated for 20 mins followed by substrate addition and measured for 3 mins by Ellma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J969S0PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50369748(CHEMBL208599)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human recombinant AChE in erythrocytes by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K938GQPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM10592(7-chloro-15-methyl-10-azatetracyclo[11.3.1.0^{2,11...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K077XJPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50556958(CHEMBL4744528)copy SMILES
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K077XJPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM10592(7-chloro-15-methyl-10-azatetracyclo[11.3.1.0^{2,11...)copy SMILEScopy InChI
Affinity DataIC50: 1.84nMAssay Description:Inhibition of human recombinant AChE in erythrocytes by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K938GQPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50556953(CHEMBL4748114)copy SMILES
Affinity DataIC50: 1.90nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K077XJPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50556954(CHEMBL4782921)copy SMILES
Affinity DataIC50: 2.90nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K077XJPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50298409((+/-)-3-chloro-6,7,10,11-tetrahydro-N-(2-(4-(6-(3,...)copy SMILEScopy InChI
Affinity DataIC50: 3.95nMAssay Description:Inhibition of human recombinant AChE in erythrocytes by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K938GQPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50556951(CHEMBL4788434)copy SMILES
Affinity DataIC50: 4.40nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K077XJPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50556956(CHEMBL4741162)copy SMILES
Affinity DataIC50: 4.40nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K077XJPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50556950(CHEMBL4743210)copy SMILES
Affinity DataIC50: 5.5nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K077XJPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50556957(CHEMBL4794769)copy SMILES
Affinity DataIC50: 5.60nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K077XJPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50298408((+/-)-3-chloro-6,7,10,11-tetrahydro-N-(2-(4-(6-(3,...)copy SMILEScopy InChI
Affinity DataIC50: 5.96nMAssay Description:Inhibition of human recombinant AChE in erythrocytes by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K938GQPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50298403((+/-)-N-(2-Hydroxyethyl)-3-chloro-6,7,10,11-tetrah...)copy SMILEScopy InChI
Affinity DataIC50: 6.75nMAssay Description:Inhibition of human recombinant AChE in erythrocytes by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K938GQPubMed
LigandPNGBDBM50523276(CHEMBL4443989)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of native porcine brain GSK-3alpha/beta using GS-1 as substrate incubated for 30 mins in presence of [gamma-33P]ATP by liquid scintillatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J969S0PubMed
TargetCholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50556958(CHEMBL4744528)copy SMILES
Affinity DataIC50: 7.30nMAssay Description:Inhibition of human serum BChE using butyrylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K077XJPubMed
LigandPNGBDBM50523265(CHEMBL4531222)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of native porcine brain GSK-3alpha/beta using GS-1 as substrate incubated for 30 mins in presence of [gamma-33P]ATP by liquid scintillatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J969S0PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50298405((+/-)-N-(2-azidoethyl)-3-chloro-6,7,10,11-tetrahyd...)copy SMILEScopy InChI
Affinity DataIC50: 8.69nMAssay Description:Inhibition of human recombinant AChE in erythrocytes by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K938GQPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50523276(CHEMBL4443989)copy SMILEScopy InChI
Affinity DataIC50: 9.5nMAssay Description:Inhibition of human recombinant AChE using ATCh as substrate preincubated for 20 mins followed by substrate addition and measured for 3 mins by Ellma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J969S0PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50298402((+/-)-N-(2-Hydroxyethyl)-3-chloro-6,7,10,11-tetrah...)copy SMILEScopy InChI
Affinity DataIC50: 9.66nMAssay Description:Inhibition of human recombinant AChE in erythrocytes by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K938GQPubMed
LigandPNGBDBM50523277(CHEMBL4516356)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of native porcine brain GSK-3alpha/beta using GS-1 as substrate incubated for 30 mins in presence of [gamma-33P]ATP by liquid scintillatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J969S0PubMed
LigandPNGBDBM50523269(CHEMBL4446287)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of native porcine brain GSK-3alpha/beta using GS-1 as substrate incubated for 30 mins in presence of [gamma-33P]ATP by liquid scintillatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J969S0PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50523267(CHEMBL4559936)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant AChE using ATCh as substrate preincubated for 20 mins followed by substrate addition and measured for 3 mins by Ellma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J969S0PubMed
LigandPNGBDBM50523266(CHEMBL4444585)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of native porcine brain GSK-3alpha/beta using GS-1 as substrate incubated for 30 mins in presence of [gamma-33P]ATP by liquid scintillatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J969S0PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50298406((+/-)-N-(2-azidoethyl)-3-chloro-6,7,10,11-tetrahyd...)copy SMILEScopy InChI
Affinity DataIC50: 13.7nMAssay Description:Inhibition of human recombinant AChE in erythrocytes by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K938GQPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50523262(CHEMBL4443468)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant AChE using ATCh as substrate preincubated for 20 mins followed by substrate addition and measured for 3 mins by Ellma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J969S0PubMed
LigandPNGBDBM50523282(CHEMBL4515295)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of native porcine brain GSK-3alpha/beta using GS-1 as substrate incubated for 30 mins in presence of [gamma-33P]ATP by liquid scintillatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J969S0PubMed
LigandPNGBDBM50523267(CHEMBL4559936)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of native porcine brain GSK-3alpha/beta using GS-1 as substrate incubated for 30 mins in presence of [gamma-33P]ATP by liquid scintillatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J969S0PubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
CNRS

Curated by ChEMBL
LigandPNGBDBM50523278(CHEMBL4463060)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant CDK5/p25 using histone H1 as substrate in presence of [gamma-33P]ATP incubated for 30 mins by liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J969S0PubMed
LigandPNGBDBM50523262(CHEMBL4443468)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of native porcine brain GSK-3alpha/beta using GS-1 as substrate incubated for 30 mins in presence of [gamma-33P]ATP by liquid scintillatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J969S0PubMed
TargetCholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50523275(CHEMBL4537026)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of human serum BChE using BTCh as substrate preincubated for 20 mins followed by substrate addition and measured for 3 mins by Ellman's me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J969S0PubMed
LigandPNGBDBM50523268(CHEMBL4593316)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of native porcine brain GSK-3alpha/beta using GS-1 as substrate incubated for 30 mins in presence of [gamma-33P]ATP by liquid scintillatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J969S0PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50523277(CHEMBL4516356)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant AChE using ATCh as substrate preincubated for 20 mins followed by substrate addition and measured for 3 mins by Ellma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J969S0PubMed
LigandPNGBDBM50399310(CHEMBL2180854)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of native porcine brain GSK-3alpha/beta using GS-1 as substrate incubated for 30 mins in presence of [gamma-33P]ATP by liquid scintillatio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J969S0PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50523268(CHEMBL4593316)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of human recombinant AChE using ATCh as substrate preincubated for 20 mins followed by substrate addition and measured for 3 mins by Ellma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J969S0PubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
CNRS

Curated by ChEMBL
LigandPNGBDBM50399310(CHEMBL2180854)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant CDK5/p25 using histone H1 as substrate in presence of [gamma-33P]ATP incubated for 30 mins by liquid scintillation co...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J969S0PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50556955(CHEMBL4782267)copy SMILES
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K077XJPubMed
LigandPNGBDBM50523274(CHEMBL4537142)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of native porcine brain GSK-3alpha/beta using GS-1 as substrate incubated for 30 mins in presence of [gamma-33P]ATP by liquid scintillatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J969S0PubMed
LigandPNGBDBM50523273(CHEMBL4459540)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of native porcine brain GSK-3alpha/beta using GS-1 as substrate incubated for 30 mins in presence of [gamma-33P]ATP by liquid scintillatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J969S0PubMed
TargetCholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50556952(CHEMBL4754487)copy SMILES
Affinity DataIC50: 31nMAssay Description:Inhibition of human serum BChE using butyrylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K077XJPubMed
LigandPNGBDBM50523278(CHEMBL4463060)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of native porcine brain GSK-3alpha/beta using GS-1 as substrate incubated for 30 mins in presence of [gamma-33P]ATP by liquid scintillatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J969S0PubMed
TargetCholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of human serum BChE using BTCh as substrate preincubated for 20 mins followed by substrate addition and measured for 3 mins by Ellman's me...More data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50556954(CHEMBL4782921)copy SMILES
Affinity DataIC50: 36nMAssay Description:Inhibition of human serum BChE using butyrylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K077XJPubMed
LigandPNGBDBM50523271(CHEMBL4566076)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of native porcine brain GSK-3alpha/beta using GS-1 as substrate incubated for 30 mins in presence of [gamma-33P]ATP by liquid scintillatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J969S0PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50298404((+/-)-N-(2-chloroethyl)-3-chloro-6,7,10,11-tetrahy...)copy SMILEScopy InChI
Affinity DataIC50: 43.3nMAssay Description:Inhibition of human recombinant AChE in erythrocytes by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K938GQPubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
CNRS

Curated by ChEMBL
LigandPNGBDBM50523263(CHEMBL4483607)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant CDK5/p25 using histone H1 as substrate in presence of [gamma-33P]ATP incubated for 30 mins by liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J969S0PubMed
TargetCholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50556953(CHEMBL4748114)copy SMILES
Affinity DataIC50: 52nMAssay Description:Inhibition of human serum BChE using butyrylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K077XJPubMed
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