TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of JAK3 expressed in insect Sf21 cells assessed as inhibition of biotinylated substrate phosphorylationMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of JAK3 expressed in Sf21 cellsMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of JAK3 expressed in insect Sf21 cells assessed as inhibition of biotinylated substrate phosphorylationMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of JAK3 expressed in Sf21 cellsMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of JAK3 expressed in insect Sf21 cells assessed as inhibition of biotinylated substrate phosphorylationMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 5nMpH: 7.5 T: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit JAK3 RTK activity. The compounds were incubated with enzyme, 10 uM ATP, and ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of JAK3 expressed in insect Sf21 cells assessed as inhibition of biotinylated substrate phosphorylationMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of JAK3 expressed in insect Sf21 cells assessed as inhibition of biotinylated substrate phosphorylationMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of JAK3 expressed in Sf21 cellsMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of JAK3 expressed in insect Sf21 cells assessed as inhibition of biotinylated substrate phosphorylationMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of JAK3 expressed in insect Sf21 cells assessed as inhibition of biotinylated substrate phosphorylationMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of JAK3 expressed in insect Sf21 cells assessed as inhibition of biotinylated substrate phosphorylationMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of JAK3 expressed in insect Sf21 cells assessed as inhibition of biotinylated substrate phosphorylationMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of JAK3 expressed in Sf21 cellsMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of JAK3 expressed in insect Sf21 cells assessed as inhibition of biotinylated substrate phosphorylationMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 13.5nMAssay Description:Inhibition of JAK3 expressed in Sf21 cellsMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of JAK3 expressed in Sf21 cellsMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of JAK3 expressed in insect Sf21 cells assessed as inhibition of biotinylated substrate phosphorylationMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of JAK3 expressed in Sf21 cellsMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 17.5nMAssay Description:Inhibition of JAK3 expressed in Sf21 cellsMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 23.5nMAssay Description:Inhibition of JAK3 expressed in Sf21 cellsMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of JAK3 expressed in Sf21 cellsMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of JAK3 expressed in Sf21 cellsMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of JAK3 expressed in Sf21 cellsMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Inhibition of JAK3 expressed in insect Sf21 cells assessed as inhibition of biotinylated substrate phosphorylationMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Inhibition of JAK3 expressed in insect Sf21 cells assessed as inhibition of biotinylated substrate phosphorylationMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 61nMAssay Description:Inhibition of JAK3 expressed in insect Sf21 cells assessed as inhibition of biotinylated substrate phosphorylationMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of JAK3 expressed in Sf21 cellsMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 72nMAssay Description:Inhibition of JAK3 expressed in Sf21 cellsMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of JAK3 expressed in Sf21 cellsMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 98nMpH: 7.5 T: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit JAK3 RTK activity. The compounds were incubated with enzyme, 10 uM ATP, and ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 109nMAssay Description:Inhibition of JAK3 expressed in Sf21 cellsMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 142nMAssay Description:Inhibition of JAK3 expressed in Sf21 cellsMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of Zap70-mediated inhibition of biotinylated substrate phosphorylationMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of JAK3 expressed in insect Sf21 cells assessed as inhibition of biotinylated substrate phosphorylationMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 237nMAssay Description:Inhibition of JAK3 expressed in Sf21 cellsMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of JAK3 expressed in Sf21 cellsMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of SYK-mediated inhibition of biotinylated substrate phosphorylationMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of LCK-mediated inhibition of biotinylated substrate phosphorylationMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 354nMAssay Description:Inhibition of JAK3 expressed in Sf21 cellsMore data for this Ligand-Target Pair
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 540nMAssay Description:Inhibition of MK2-mediated inhibition of biotinylated substrate phosphorylationMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 592nMAssay Description:Inhibition of JAK3 expressed in Sf21 cellsMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 686nMAssay Description:Inhibition of JAK3 expressed in Sf21 cellsMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 5A(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 689nMAssay Description:Inhibition of STAT5 phosphorylation in IL2-stimulated healthy human T cells by western blottingMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 957nMpH: 7.5 T: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit JAK3 RTK activity. The compounds were incubated with enzyme, 10 uM ATP, and ...More data for this Ligand-Target Pair
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of MK2-mediated inhibition of biotinylated substrate phosphorylationMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of LCK-mediated inhibition of biotinylated substrate phosphorylationMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of LCK-mediated inhibition of biotinylated substrate phosphorylationMore data for this Ligand-Target Pair
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of MK2-mediated inhibition of biotinylated substrate phosphorylationMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Johnson& Johnson Pharmaceutical Research& Development L.L.C. 920 Route 202
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Zap70-mediated inhibition of biotinylated substrate phosphorylationMore data for this Ligand-Target Pair