Compile Data Set for Download or QSAR
Found 141 with Last Name = 'balakrishna' and Initial = 'r'
TargetToll-like receptor 8(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50380489(CHEMBL2018888)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Antagonist activity at TLR8 in human PBMC assessed as inhibition of CL075-TNF-alpha release after 12 hrs by bead array assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PVXPubMed
TargetToll-like receptor 8(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50380489(CHEMBL2018888)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Antagonist activity at TLR8 in human PBMC assessed as inhibition of CL075-induced IL-1beta release after 12 hrs by bead array assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PVXPubMed
TargetToll-like receptor 8(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50380489(CHEMBL2018888)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Antagonist activity at TLR8 in human PBMC assessed as inhibition of CL075-induced IL-8 release after 12 hrs by bead array assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PVXPubMed
TargetToll-like receptor 7(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50380489(CHEMBL2018888)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Antagonist activity at TLR7 in human PBMC assessed as inhibition of gardiquimod-induced CCL2 release after 12 hrs by bead array assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PVXPubMed
TargetToll-like receptor 7(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50380489(CHEMBL2018888)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Antagonist activity at TLR7 in human PBMC assessed as inhibition of gardiquimod-induced IL-8 release after 12 hrs by bead array assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PVXPubMed
TargetToll-like receptor 7(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50380489(CHEMBL2018888)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Antagonist activity at TLR7 in human PBMC assessed as inhibition of gardiquimod-induced IL-6 release after 12 hrs by bead array assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PVXPubMed
TargetToll-like receptor 8(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50380489(CHEMBL2018888)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Antagonist activity at TLR8 in human PBMC assessed as inhibition of CL075-induced IL-6 release after 12 hrs by bead array assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PVXPubMed
TargetToll-like receptor 7(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50380489(CHEMBL2018888)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Antagonist activity at TLR7 in human PBMC assessed as inhibition of gardiquimod-induced TNF-alpha release after 12 hrs by bead array assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PVXPubMed
TargetToll-like receptor 7(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50380489(CHEMBL2018888)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Antagonist activity at TLR7 in human PBMC assessed as inhibition of gardiquimod-induced IL-1beta release after 12 hrs by bead array assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PVXPubMed
TargetToll-like receptor 8(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50380489(CHEMBL2018888)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Antagonist activity at TLR8 in human PBMC assessed as inhibition of CL075-induced CCL2 release after 12 hrs by bead array assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PVXPubMed
TargetToll-like receptor 8(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50380489(CHEMBL2018888)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Antagonist activity at TLR8 in human PBMC assessed as inhibition of CL075-induced CXCL10 release after 12 hrs by bead array assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PVXPubMed
TargetToll-like receptor 7(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50380489(CHEMBL2018888)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Antagonist activity at TLR7 in human PBMC assessed as inhibition of gardiquimod-induced CXCL10 release after 12 hrs by bead array assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PVXPubMed
TargetToll-like receptor 7(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50380495(CHEMBL2018887)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Agonist activity at human TLR7 expressed in HEK-Blue cells assessed as increase in NFkappaB activation by sAP reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PVXPubMed
TargetToll-like receptor 7(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50380497(CHEMBL2018897)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Agonist activity at human TLR7 expressed in HEK-Blue cells assessed as increase in NFkappaB activation by sAP reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PVXPubMed
TargetTranscription factor p65(Homo sapiens (Human))
MediQuest Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM50195806(CHEMBL384590 | N-(3-(4-(3-aminopropylamino)butylam...)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Inhibition of NFkappaB in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34X4HPubMed
TargetToll-like receptor 7(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50380496(CHEMBL2018896)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Agonist activity at human TLR7 expressed in HEK-Blue cells assessed as increase in NFkappaB activation by sAP reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PVXPubMed
TargetTranscription factor p65(Homo sapiens (Human))
MediQuest Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM50195808(CHEMBL218163 | N-(3-(4-(3-aminopropylamino)butylam...)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:Inhibition of NFkappaB in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34X4HPubMed
TargetTranscription factor p65(Homo sapiens (Human))
MediQuest Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM50195809(CHEMBL218434 | N-(3-(4-(3-aminopropylamino)butylam...)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Inhibition of NFkappaB in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34X4HPubMed
TargetToll-like receptor 7(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50380499(CHEMBL2018899)copy SMILEScopy InChI
Affinity DataIC50: 450nMAssay Description:Agonist activity at human TLR7 expressed in HEK-Blue cells assessed as increase in NFkappaB activation by sAP reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PVXPubMed
TargetToll-like receptor 7(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50380498(CHEMBL2018898)copy SMILEScopy InChI
Affinity DataIC50: 560nMAssay Description:Agonist activity at human TLR7 expressed in HEK-Blue cells assessed as increase in NFkappaB activation by sAP reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PVXPubMed
TargetToll-like receptor 7(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50380491(CHEMBL2018893)copy SMILEScopy InChI
Affinity DataIC50: 560nMAssay Description:Agonist activity at human TLR7 expressed in HEK-Blue cells assessed as increase in NFkappaB activation by sAP reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PVXPubMed
TargetToll-like receptor 4(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50410807(POLUMYXIN B | POLYMIXIN B | POLYMYXIN B)copy SMILEScopy InChI
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of induction of NF-kappaB by LPS in HEK293 cells co-transfected with TLR4, CD14 and MD2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0B64PubMed
TargetToll-like receptor 7(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50380494(CHEMBL2018895)copy SMILEScopy InChI
Affinity DataIC50: 1.42E+3nMAssay Description:Agonist activity at human TLR7 expressed in HEK-Blue cells assessed as increase in NFkappaB activation by sAP reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PVXPubMed
TargetToll-like receptor 7(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50380490(CHEMBL2018892)copy SMILEScopy InChI
Affinity DataIC50: 2.05E+3nMAssay Description:Agonist activity at human TLR7 expressed in HEK-Blue cells assessed as increase in NFkappaB activation by sAP reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PVXPubMed
TargetTranscription factor p65(Homo sapiens (Human))
MediQuest Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM50195807(CHEMBL218282 | N-(3-(4-(3-aminopropylamino)butylam...)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of NFkappaB in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34X4HPubMed
TargetToll-like receptor 7(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50380493(CHEMBL2018894)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Agonist activity at human TLR7 expressed in HEK-Blue cells assessed as increase in NFkappaB activation by sAP reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PVXPubMed
TargetToll-like receptor 7(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50380489(CHEMBL2018888)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+3nMAssay Description:Antagonist activity at human TLR7 expressed in HEK-Blue cells assessed as inhibition of gardiquimod-induced NFkappaB activation by sAP reporter gene ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PVXPubMed
TargetToll-like receptor 8(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50380489(CHEMBL2018888)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+3nMAssay Description:Antagonist activity at human TLR8 expressed in HEK-Blue cells assessed as inhibition of CL075-induced NFkappaB activation by sAP reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PVXPubMed
TargetToll-like receptor 7(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50380501(CHEMBL2018901)copy SMILEScopy InChI
Affinity DataIC50: 4.02E+3nMAssay Description:Agonist activity at human TLR7 expressed in HEK-Blue cells assessed as increase in NFkappaB activation by sAP reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PVXPubMed
TargetToll-like receptor 4(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50410808(CHEMBL535384)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of induction of NF-kappaB by LPS in HEK293 cells co-transfected with TLR4, CD14 and MD2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0B64PubMed
TargetToll-like receptor 8(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50380504(CHEMBL2018891)copy SMILEScopy InChI
Affinity DataIC50: 4.65E+3nMAssay Description:Antagonist activity at human TLR8 expressed in HEK-Blue cells assessed as inhibition of CL075-induced NFkappaB activation by sAP reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PVXPubMed
TargetToll-like receptor 8(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50380497(CHEMBL2018897)copy SMILEScopy InChI
Affinity DataIC50: 4.78E+3nMAssay Description:Agonist activity at human TLR8 expressed in HEK-Blue cells assessed as increase in NFkappaB activation by sAP reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PVXPubMed
TargetToll-like receptor 7(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50380502(CHEMBL2018902)copy SMILEScopy InChI
Affinity DataIC50: 5.40E+3nMAssay Description:Agonist activity at human TLR7 expressed in HEK-Blue cells assessed as increase in NFkappaB activation by sAP reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PVXPubMed
TargetToll-like receptor 4(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50410816(CHEMBL537642)copy SMILEScopy InChI
Affinity DataIC50: 6.11E+3nMAssay Description:Inhibition of induction of NF-kappaB by LPS in HEK293 cells co-transfected with TLR4, CD14 and MD2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0B64PubMed
TargetToll-like receptor 7(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50380500(CHEMBL2018900)copy SMILEScopy InChI
Affinity DataIC50: 7.24E+3nMAssay Description:Agonist activity at human TLR7 expressed in HEK-Blue cells assessed as increase in NFkappaB activation by sAP reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PVXPubMed
TargetToll-like receptor 4(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50410810(CHEMBL537865)copy SMILEScopy InChI
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of induction of NF-kappaB by LPS in HEK293 cells co-transfected with TLR4, CD14 and MD2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0B64PubMed
TargetToll-like receptor 4(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50410814(CHEMBL537866)copy SMILEScopy InChI
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of induction of NF-kappaB by LPS in HEK293 cells co-transfected with TLR4, CD14 and MD2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0B64PubMed
TargetToll-like receptor 8(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50380492(CHEMBL2018890)copy SMILEScopy InChI
Affinity DataIC50: 1.09E+4nMAssay Description:Antagonist activity at human TLR8 expressed in HEK-Blue cells assessed as inhibition of CL075-induced NFkappaB activation by sAP reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PVXPubMed
TargetToll-like receptor 8(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50380503(CHEMBL2018889)copy SMILEScopy InChI
Affinity DataIC50: 1.56E+4nMAssay Description:Antagonist activity at human TLR8 expressed in HEK-Blue cells assessed as inhibition of CL075-induced NFkappaB activation by sAP reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PVXPubMed
TargetToll-like receptor 7(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50380504(CHEMBL2018891)copy SMILEScopy InChI
Affinity DataIC50: 1.79E+4nMAssay Description:Antagonist activity at human TLR7 expressed in HEK-Blue cells assessed as inhibition of gardiquimod-induced NFkappaB activation by sAP reporter gene ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PVXPubMed
TargetToll-like receptor 4(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50410812(CHEMBL534488)copy SMILEScopy InChI
Affinity DataIC50: 2.76E+4nMAssay Description:Inhibition of induction of NF-kappaB by LPS in HEK293 cells co-transfected with TLR4, CD14 and MD2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0B64PubMed
TargetToll-like receptor 4(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50410806(CHEMBL538329)copy SMILEScopy InChI
Affinity DataIC50: 3.56E+4nMAssay Description:Inhibition of induction of NF-kappaB by LPS in HEK293 cells co-transfected with TLR4, CD14 and MD2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0B64PubMed
TargetToll-like receptor 4(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50410815(CHEMBL535159)copy SMILEScopy InChI
Affinity DataIC50: 5.91E+4nMAssay Description:Inhibition of induction of NF-kappaB by LPS in HEK293 cells co-transfected with TLR4, CD14 and MD2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0B64PubMed
TargetToll-like receptor 4(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50410813(CHEMBL537645)copy SMILEScopy InChI
Affinity DataIC50: 6.14E+4nMAssay Description:Inhibition of induction of NF-kappaB by LPS in HEK293 cells co-transfected with TLR4, CD14 and MD2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0B64PubMed
TargetToll-like receptor 4(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50410811(CHEMBL534939)copy SMILEScopy InChI
Affinity DataIC50: 1.64E+5nMAssay Description:Inhibition of induction of NF-kappaB by LPS in HEK293 cells co-transfected with TLR4, CD14 and MD2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0B64PubMed
TargetToll-like receptor 4(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50410809(CHEMBL534490)copy SMILEScopy InChI
Affinity DataIC50: 1.75E+5nMAssay Description:Inhibition of induction of NF-kappaB by LPS in HEK293 cells co-transfected with TLR4, CD14 and MD2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0B64PubMed
TargetToll-like receptor 4(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50410817(CHEMBL540367)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+5nMAssay Description:Inhibition of induction of NF-kappaB by LPS in HEK293 cells co-transfected with TLR4, CD14 and MD2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0B64PubMed
TargetToll-like receptor 7(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50240849(1-(2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4-ami...)copy SMILEScopy InChI
Affinity DataEC50:  2.12E+3nMAssay Description:Agonist activity at human TLR7 expressed in NFkappaB-stimulated HEK293 cells assessed as induction of secreted alkaline phosphatase expression by rep...More data for this Ligand-Target Pair
TargetToll-like receptor 7(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50320066(1-(4-Amino-2-((diethylamino)methyl)-1H-imidazo[4,5...)copy SMILEScopy InChI
Affinity DataEC50:  7.71E+3nMAssay Description:Agonist activity at human TLR7 expressed in NFkappaB-stimulated HEK293 cells assessed as induction of secreted alkaline phosphatase expression by rep...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52PS6PubMed
TargetToll-like receptor 7(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50320067(1-(4-amino-2-((ethylamino)methyl)-1H-imidazo[4,5-c...)copy SMILEScopy InChI
Affinity DataEC50:  2.00E+3nMAssay Description:Agonist activity at human TLR7 expressed in NFkappaB-stimulated HEK293 cells assessed as induction of secreted alkaline phosphatase expression by rep...More data for this Ligand-Target Pair
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