Compile Data Set for Download or QSAR
Found 59 with Last Name = 'chambers-wilson' and Initial = 'r'
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM50579244(Avoralstat | BCX-4161)copy SMILES
Affinity DataKi:  0.260nMAssay Description:Inhibition of purified human plasma kallikrein assessed as inhibition constant using H-D-Pro-Phe-Arg-pNA.2HCl as substrate measured after 3 mins by m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416926((+)-1-(3-(aminomethyl)phenyl)-N-(5-((3-cyanophenyl...)copy SMILEScopy InChI
Affinity DataKi:  0.440nMAssay Description:Inhibition of purified human plasma kallikrein assessed as inhibition constant using H-D-Pro-Phe-Arg-pNA.2HCl as substrate measured after 3 mins by m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416926((+)-1-(3-(aminomethyl)phenyl)-N-(5-((3-cyanophenyl...)copy SMILEScopy InChI
Affinity DataIC50: 0.880nMAssay Description:Inhibition of purified human plasma kallikrein using H-D-Pro-Phe-Arg-pNA.2HCl as substrate measured after 3 mins by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416773(1-(3-(aminomethyl)phenyl)-N-(5-(((cyclopropylmethy...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of purified human plasma kallikrein using H-D-Pro-Phe-Arg-pNA.2HCl as substrate measured after 3 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416926((+)-1-(3-(aminomethyl)phenyl)-N-(5-((3-cyanophenyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of purified human plasma kallikrein using H-D-Pro-Phe-Arg-pNA.2HCl as substrate measured after 3 mins by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416926((+)-1-(3-(aminomethyl)phenyl)-N-(5-((3-cyanophenyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of purified human plasma kallikrein using H-D-Pro-Phe-Arg-pNA.2HCl as substrate measured after 3 mins by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416796(1-(3-(aminomethyl)phenyl)-N-(5-(((cyclopropylmethy...)copy SMILEScopy InChI
Affinity DataIC50: 5.20nMAssay Description:Inhibition of purified human plasma kallikrein using H-D-Pro-Phe-Arg-pNA.2HCl as substrate measured after 3 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416926((+)-1-(3-(aminomethyl)phenyl)-N-(5-((3-cyanophenyl...)copy SMILEScopy InChI
Affinity DataIC50: 5.80nMAssay Description:Inhibition of endogenous human plasma kallikrein using Z-Phe-Arg-AMC.HCl as substrate measured after 5 mins by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416968((+-)-1-(3-(aminomethyl)phenyl)-N-(5-((cyclopropylm...)copy SMILEScopy InChI
Affinity DataIC50: 6.40nMAssay Description:Inhibition of purified human plasma kallikrein using H-D-Pro-Phe-Arg-pNA.2HCl as substrate measured after 3 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416830(1-(3-(aminomethyl)phenyl)-N-(5-((4-cyanophenyl)(cy...)copy SMILEScopy InChI
Affinity DataIC50: 7.20nMAssay Description:Inhibition of purified human plasma kallikrein using H-D-Pro-Phe-Arg-pNA.2HCl as substrate measured after 3 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416773(1-(3-(aminomethyl)phenyl)-N-(5-(((cyclopropylmethy...)copy SMILEScopy InChI
Affinity DataIC50: 8.51nMAssay Description:Inhibition of endogenous human plasma kallikrein using Z-Phe-Arg-AMC.HCl as substrate measured after 5 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416773(1-(3-(aminomethyl)phenyl)-N-(5-(((cyclopropylmethy...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of purified human plasma kallikrein using H-D-Pro-Phe-Arg-pNA.2HCl as substrate measured after 3 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416773(1-(3-(aminomethyl)phenyl)-N-(5-(((cyclopropylmethy...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of purified human plasma kallikrein using H-D-Pro-Phe-Arg-pNA.2HCl as substrate measured after 3 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416812(1-(3-(aminomethyl)phenyl)-N-(5-((cyclopropylmethyl...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of purified human plasma kallikrein using H-D-Pro-Phe-Arg-pNA.2HCl as substrate measured after 3 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416784(1-(3-(aminomethyl)phenyl)-N-(5-((cyclopropylmethyl...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of endogenous human plasma kallikrein using Z-Phe-Arg-AMC.HCl as substrate measured after 5 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416784(1-(3-(aminomethyl)phenyl)-N-(5-((cyclopropylmethyl...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of purified human plasma kallikrein using H-D-Pro-Phe-Arg-pNA.2HCl as substrate measured after 3 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416926((+)-1-(3-(aminomethyl)phenyl)-N-(5-((3-cyanophenyl...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of endogenous human plasma kallikrein using Z-Phe-Arg-AMC.HCl as substrate measured after 5 mins by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416926((+)-1-(3-(aminomethyl)phenyl)-N-(5-((3-cyanophenyl...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of endogenous human plasma kallikrein using Z-Phe-Arg-AMC.HCl as substrate measured after 5 mins by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416796(1-(3-(aminomethyl)phenyl)-N-(5-(((cyclopropylmethy...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of endogenous human plasma kallikrein using Z-Phe-Arg-AMC.HCl as substrate measured after 5 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416830(1-(3-(aminomethyl)phenyl)-N-(5-((4-cyanophenyl)(cy...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of endogenous human plasma kallikrein using Z-Phe-Arg-AMC.HCl as substrate measured after 5 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416773(1-(3-(aminomethyl)phenyl)-N-(5-(((cyclopropylmethy...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of endogenous human plasma kallikrein using Z-Phe-Arg-AMC.HCl as substrate measured after 5 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416773(1-(3-(aminomethyl)phenyl)-N-(5-(((cyclopropylmethy...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of endogenous human plasma kallikrein using Z-Phe-Arg-AMC.HCl as substrate measured after 5 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416812(1-(3-(aminomethyl)phenyl)-N-(5-((cyclopropylmethyl...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of endogenous human plasma kallikrein using Z-Phe-Arg-AMC.HCl as substrate measured after 5 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416779(1-(3-(aminomethyl)phenyl)-N-(3-((cyclopropylmethox...)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Inhibition of purified human plasma kallikrein using H-D-Pro-Phe-Arg-pNA.2HCl as substrate measured after 3 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416775(1-(3-(aminomethyl)phenyl)-N-(3-((cyclopropylmethox...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of purified human plasma kallikrein using H-D-Pro-Phe-Arg-pNA.2HCl as substrate measured after 3 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416736(1-(3-(aminomethyl)phenyl)-N-(3-((cyclopropylmethox...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of purified human plasma kallikrein using H-D-Pro-Phe-Arg-pNA.2HCl as substrate measured after 3 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416752(1-(3-(aminomethyl)phenyl)-N-(5-(ethoxy(phenyl)meth...)copy SMILEScopy InChI
Affinity DataIC50: 134nMAssay Description:Inhibition of purified human plasma kallikrein using H-D-Pro-Phe-Arg-pNA.2HCl as substrate measured after 3 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416744(1-(3-(aminomethyl)phenyl)-N-(2-fluoro-3-(hydroxy(p...)copy SMILEScopy InChI
Affinity DataIC50: 149nMAssay Description:Inhibition of purified human plasma kallikrein using H-D-Pro-Phe-Arg-pNA.2HCl as substrate measured after 3 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416755(1-(3-(aminomethyl)phenyl)-N-(2-fluoro-5-(methoxy(p...)copy SMILEScopy InChI
Affinity DataIC50: 231nMAssay Description:Inhibition of purified human plasma kallikrein using H-D-Pro-Phe-Arg-pNA.2HCl as substrate measured after 3 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416968((+-)-1-(3-(aminomethyl)phenyl)-N-(5-((cyclopropylm...)copy SMILEScopy InChI
Affinity DataIC50: 287nMAssay Description:Inhibition of endogenous human plasma kallikrein using Z-Phe-Arg-AMC.HCl as substrate measured after 5 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416775(1-(3-(aminomethyl)phenyl)-N-(3-((cyclopropylmethox...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of endogenous human plasma kallikrein using Z-Phe-Arg-AMC.HCl as substrate measured after 5 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM50579242(CHEMBL4848851)copy SMILES
Affinity DataIC50: 395nMAssay Description:Inhibition of purified human plasma kallikrein using H-D-Pro-Phe-Arg-pNA.2HCl as substrate measured after 3 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM50579241(CHEMBL4868267)copy SMILES
Affinity DataIC50: 395nMAssay Description:Inhibition of purified human plasma kallikrein using H-D-Pro-Phe-Arg-pNA.2HCl as substrate measured after 3 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM50579243(CHEMBL4875350)copy SMILES
Affinity DataIC50: 577nMAssay Description:Inhibition of purified human plasma kallikrein using H-D-Pro-Phe-Arg-pNA.2HCl as substrate measured after 3 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416963(1-(3-(aminomethyl)phenyl)-N-(4-((cyclopropylmethox...)copy SMILEScopy InChI
Affinity DataIC50: 651nMAssay Description:Inhibition of purified human plasma kallikrein using H-D-Pro-Phe-Arg-pNA.2HCl as substrate measured after 3 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416776(1-(3-(aminomethyl)phenyl)-N-(3-((cyclopropylmethox...)copy SMILEScopy InChI
Affinity DataIC50: 708nMAssay Description:Inhibition of purified human plasma kallikrein using H-D-Pro-Phe-Arg-pNA.2HCl as substrate measured after 3 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416741(1-(3-(aminomethyl)phenyl)-N-(2-fluoro-5-(hydroxy(p...)copy SMILEScopy InChI
Affinity DataIC50: 710nMAssay Description:Inhibition of purified human plasma kallikrein using H-D-Pro-Phe-Arg-pNA.2HCl as substrate measured after 3 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416736(1-(3-(aminomethyl)phenyl)-N-(3-((cyclopropylmethox...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of endogenous human plasma kallikrein using Z-Phe-Arg-AMC.HCl as substrate measured after 5 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416776(1-(3-(aminomethyl)phenyl)-N-(3-((cyclopropylmethox...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of endogenous human plasma kallikrein using Z-Phe-Arg-AMC.HCl as substrate measured after 5 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416966(1-(3-(Aminomethyl)phenyl)-N-(2-fluoro-4-(hydroxy(p...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of purified human plasma kallikrein using H-D-Pro-Phe-Arg-pNA.2HCl as substrate measured after 3 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416779(1-(3-(aminomethyl)phenyl)-N-(3-((cyclopropylmethox...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of endogenous human plasma kallikrein using Z-Phe-Arg-AMC.HCl as substrate measured after 5 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM50579239(CHEMBL4845951)copy SMILES
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of purified human plasma kallikrein using H-D-Pro-Phe-Arg-pNA.2HCl as substrate measured after 3 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM50579240(CHEMBL4867482)copy SMILES
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of purified human plasma kallikrein using H-D-Pro-Phe-Arg-pNA.2HCl as substrate measured after 3 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416752(1-(3-(aminomethyl)phenyl)-N-(5-(ethoxy(phenyl)meth...)copy SMILEScopy InChI
Affinity DataIC50: 1.28E+3nMAssay Description:Inhibition of endogenous human plasma kallikrein using Z-Phe-Arg-AMC.HCl as substrate measured after 5 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM50579238(CHEMBL4848716)copy SMILES
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of purified human plasma kallikrein using H-D-Pro-Phe-Arg-pNA.2HCl as substrate measured after 3 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasminogen(Homo sapiens (Human))TBA
LigandPNGBDBM416926((+)-1-(3-(aminomethyl)phenyl)-N-(5-((3-cyanophenyl...)copy SMILEScopy InChI
Affinity DataIC50: 3.97E+3nMAssay Description:Inhibition of human plasmin using Z-Lys-SBzl as substrate measured immediately by plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetTrypsin(Homo sapiens (Human))TBA
LigandPNGBDBM416926((+)-1-(3-(aminomethyl)phenyl)-N-(5-((3-cyanophenyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human trypsin using Nalpha-Benzoyl-L-Arginine p-nitroaniline as substrate measured after 5 mins by plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM50579235(CHEMBL4876796)copy SMILES
Affinity DataIC50: 1.54E+4nMAssay Description:Inhibition of purified human plasma kallikrein using H-D-Pro-Phe-Arg-pNA.2HCl as substrate measured after 3 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM50579236(CHEMBL4849589)copy SMILES
Affinity DataIC50: 2.26E+4nMAssay Description:Inhibition of purified human plasma kallikrein using H-D-Pro-Phe-Arg-pNA.2HCl as substrate measured after 3 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM50579237(CHEMBL4850991)copy SMILES
Affinity DataIC50: 2.73E+4nMAssay Description:Inhibition of purified human plasma kallikrein using H-D-Pro-Phe-Arg-pNA.2HCl as substrate measured after 3 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
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