Compile Data Set for Download or QSAR
Found 340 with Last Name = 'deprez-poulain' and Initial = 'r'
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50427703(CHEMBL2324220)copy SMILEScopy InChI
Affinity DataKi:  1.70nMAssay Description:Inhibition of human recombinant IDE expressed in CHO cells in presence of [125I]-insulin by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5ZT5PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50462575(CHEMBL4238121)copy SMILEScopy InChI
Affinity DataKi:  29nMAssay Description:Inhibition human FA10a using Boc-LeuGly-Arg-AMC fluorogenic substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetProthrombin(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50514426(CHEMBL4574713)copy SMILEScopy InChI
Affinity DataKi:  50nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8C0RPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50514409(CHEMBL4549938)copy SMILEScopy InChI
Affinity DataKi:  600nMAssay Description:Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) using carboxyfluoresceine-labeled phosphotyrosine octapeptide incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8C0RPubMed
TargetBifunctional ligase/repressor BirA(Staphylococcus aureus)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50514425(CHEMBL4462026)copy SMILEScopy InChI
Affinity DataKi:  1.40E+3nMAssay Description:Binding affinity to Staphylococcus aureus biotin protein ligaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8C0RPubMed
TargetNAD kinase 1(Listeria monocytogenes serovar 1/2a (strain ATCC B...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50514423(CHEMBL4552749)copy SMILEScopy InChI
Affinity DataKi:  2.50E+4nMAssay Description:Inhibition of Listeria monocytogenes NAD kinase assessed as suppression of reduced NADP formation by yeast glucose-6-phosphate dehydrogenase coupled ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8C0RPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM23234(1,2,5-oxadiazole, OXD2 | 4-amino-1,2,5-oxadiazole-...)copy SMILEScopy InChI
Affinity DataKi:  4.20E+5nMAssay Description:Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) using carboxyfluoresceine-labeled phosphotyrosine octapeptide incubated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8C0RPubMed
TargetCoagulation factor X(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50232690(4-Aminomethyl-Benzamidine | CHEMBL187301)copy SMILEScopy InChI
Affinity DataKi:  6.80E+5nMAssay Description:Inhibition human FA10a using Boc-LeuGly-Arg-AMC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8C0RPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50514419(CHEMBL4454339)copy SMILEScopy InChI
Affinity DataKi: >5.00E+6nMAssay Description:Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) using carboxyfluoresceine-labeled phosphotyrosine octapeptide incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8C0RPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50514420(CHEMBL4459159)copy SMILEScopy InChI
Affinity DataKi: >5.00E+6nMAssay Description:Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) using carboxyfluoresceine-labeled phosphotyrosine octapeptide incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8C0RPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50514421(CHEMBL4438181)copy SMILEScopy InChI
Affinity DataKi: >5.00E+6nMAssay Description:Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) using carboxyfluoresceine-labeled phosphotyrosine octapeptide incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8C0RPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50514422(CHEMBL4466928)copy SMILEScopy InChI
Affinity DataKi: >5.00E+6nMAssay Description:Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) using carboxyfluoresceine-labeled phosphotyrosine octapeptide incubated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8C0RPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50514412(CHEMBL4462216)copy SMILEScopy InChI
Affinity DataKi: >5.00E+6nMAssay Description:Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) using carboxyfluoresceine-labeled phosphotyrosine octapeptide incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8C0RPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50514424(CHEMBL4452459)copy SMILEScopy InChI
Affinity DataKi: >5.00E+6nMAssay Description:Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) using carboxyfluoresceine-labeled phosphotyrosine octapeptide incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8C0RPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50514411(CHEMBL4574617)copy SMILEScopy InChI
Affinity DataKi: >5.00E+6nMAssay Description:Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) using carboxyfluoresceine-labeled phosphotyrosine octapeptide incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8C0RPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50514410(CHEMBL4566571)copy SMILEScopy InChI
Affinity DataKi: >5.00E+6nMAssay Description:Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) using carboxyfluoresceine-labeled phosphotyrosine octapeptide incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8C0RPubMed
TargetCoagulation factor X(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50514418(CHEMBL4572188)copy SMILEScopy InChI
Affinity DataKi:  5.50E+6nMAssay Description:Inhibition human FA10a using Boc-LeuGly-Arg-AMC fluorogenic substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8C0RPubMed
TargetNeprilysin(Homo sapiens (Human))
INSERM

Curated by ChEMBL
LigandPNGBDBM21641(2-(2-benzyl-3-sulfanylpropanamido)acetic acid | CH...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human NEP-mediated amyloid beta hydrolysisMore data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
INSERM

Curated by ChEMBL
LigandPNGBDBM50351798(CHEMBL1824184)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Displacement of [125I][Sar1,Ile8]-AT-II from human recombinant AT1 receptor expressed in HEK293 cells after 120 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78FKWPubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50525490(CHEMBL4437643)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant IDE exosite (unknown origin) expressed in Escherichia coli using insulin as substrate incubated for 4 hrs by AlphaLisa assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetM1 family aminopeptidase(Plasmodium falciparum (isolate FcB1 / Columbia))
Inserm

Curated by ChEMBL
LigandPNGBDBM50206554(CHEMBL219777 | N-(4-fluoro-benzyl)-N'-hydroxy-2-[1...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M908B3PubMed
TargetHistidine-rich protein PFHRP-II(Plasmodium falciparum)
Universit£ de Lille II

Curated by ChEMBL
LigandPNGBDBM50123594((7-Chloro-quinolin-4-yl)-{3-[4-(3-dibutylamino-pro...)copy SMILEScopy InChI
Affinity DataIC50: 6.70nMAssay Description:In vitro inhibition of beta-hematin formationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6DDCPubMed
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
INSERM

Curated by ChEMBL
LigandPNGBDBM50056302(1-Butyl-5-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmeth...)copy SMILEScopy InChI
Affinity DataIC50: 9.10nMAssay Description:Displacement of [125I][Sar1,Ile8]-AT-II from human recombinant AT1 receptor expressed in HEK293 cells after 120 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78FKWPubMed
TargetLuciferin 4-monooxygenase(Photinus pyralis)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50514408(CHEMBL4435351)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of Photinus pyralis luciferase using ATP and D-luciferin in presence of Coenzyme A and DL-cysteine by luminescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8C0RPubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
INSERM

Curated by ChEMBL
LigandPNGBDBM21642((2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolid...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of human ACE-mediated amyloid beta hydrolysisMore data for this Ligand-Target Pair
TargetM1 family aminopeptidase(Plasmodium falciparum (isolate FcB1 / Columbia))
Inserm

Curated by ChEMBL
LigandPNGBDBM50206558(CHEMBL375521 | N-hydroxy-N'-(4-phenyl-butyl)-2-[1-...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M908B3PubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM34233(2-Phenyl-benzo[d]isoselenazol-3-one | 2-Phenyl-ben...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant IDE expressed in Escherichia coli BL21 (DE3) cells using insulin as substrate preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5ZT5PubMed
TargetHistidine-rich protein PFHRP-II(Plasmodium falciparum)
Universit£ de Lille II

Curated by ChEMBL
LigandPNGBDBM50123579(CHEMBL345958 | [3-(4-{3-[Bis-(4-nitro-benzyl)-amin...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:In vitro inhibition of beta-hematin formationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6DDCPubMed
TargetHistidine-rich protein PFHRP-II(Plasmodium falciparum)
Universit£ de Lille II

Curated by ChEMBL
LigandPNGBDBM50123587((7-Chloro-quinolin-4-yl)-(3-{4-[3-(cyclopropylmeth...)copy SMILEScopy InChI
Affinity DataIC50: 23.3nMAssay Description:In vitro inhibition of beta-hematin formationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6DDCPubMed
TargetHistidine-rich protein PFHRP-II(Plasmodium falciparum)
Universit£ de Lille II

Curated by ChEMBL
LigandPNGBDBM50409777(CHEMBL2111198)copy SMILEScopy InChI
Affinity DataIC50: 23.5nMAssay Description:In vitro inhibition of beta-hematin formationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6DDCPubMed
TargetHistidine-rich protein PFHRP-II(Plasmodium falciparum)
Universit£ de Lille II

Curated by ChEMBL
LigandPNGBDBM50123575((3-{4-[3-(Bis-cyclopropylmethyl-amino)-propyl]-pip...)copy SMILEScopy InChI
Affinity DataIC50: 27.1nMAssay Description:In vitro inhibition of beta-hematin formationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6DDCPubMed
TargetAminopeptidase N(Homo sapiens (Human))
Universit£ de Lille 2

Curated by ChEMBL
LigandPNGBDBM50131276(CHEMBL328470 | N-(3-{4-[3-(7-Chloro-quinolin-4-yla...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibitory activity against mammalian Aminopeptidase N (APN)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20G3KPKPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
INSERM

Curated by ChEMBL
LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of human erythrocyte carbonic anhydrase-2 assessed as hydrolysis of 4-nitrophenylacetateMore data for this Ligand-Target Pair
TargetHistidine-rich protein PFHRP-II(Plasmodium falciparum)
Universit£ de Lille II

Curated by ChEMBL
LigandPNGBDBM50123577(CHEMBL152862 | Cyclopropanecarboxylic acid (3-{4-[...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:In vitro inhibition of beta-hematin formationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6DDCPubMed
TargetHistidine-rich protein PFHRP-II(Plasmodium falciparum)
Universit£ de Lille II

Curated by ChEMBL
LigandPNGBDBM50123561(CHEMBL149751 | N-(3-(4-(3-(7-chloroquinolin-4-ylam...)copy SMILEScopy InChI
Affinity DataIC50: 34.2nMAssay Description:In vitro inhibition of beta-hematin formationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6DDCPubMed
TargetHistidine-rich protein PFHRP-II(Plasmodium falciparum)
Universit£ de Lille II

Curated by ChEMBL
LigandPNGBDBM50123569(CHEMBL357111 | N-(3-{4-[3-(7-Chloro-quinolin-4-yla...)copy SMILEScopy InChI
Affinity DataIC50: 35.6nMAssay Description:In vitro inhibition of beta-hematin formationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6DDCPubMed
TargetHistidine-rich protein PFHRP-II(Plasmodium falciparum)
Universit£ de Lille II

Curated by ChEMBL
LigandPNGBDBM50123558((7-Chloro-quinolin-4-yl)-(3-{4-[3-(3-phenoxy-benzy...)copy SMILEScopy InChI
Affinity DataIC50: 37.5nMAssay Description:In vitro inhibition of beta-hematin formationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6DDCPubMed
TargetHistidine-rich protein PFHRP-II(Plasmodium falciparum)
Universit£ de Lille II

Curated by ChEMBL
LigandPNGBDBM50123571((7-Chloro-quinolin-4-yl)-(3-{4-[3-(4-nitro-benzyla...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:In vitro inhibition of beta-hematin formationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6DDCPubMed
TargetHistidine-rich protein PFHRP-II(Plasmodium falciparum)
Universit£ de Lille II

Curated by ChEMBL
LigandPNGBDBM50123562(CHEMBL152635 | N-(3-(4-(3-(7-chloroquinolin-4-ylam...)copy SMILEScopy InChI
Affinity DataIC50: 40.2nMAssay Description:In vitro inhibition of beta-hematin formationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6DDCPubMed
TargetM1 family aminopeptidase(Plasmodium falciparum (isolate FcB1 / Columbia))
Inserm

Curated by ChEMBL
LigandPNGBDBM50206550(2-benzyl-N-hydroxy-N'-(2-methyl-benzyl)-malonamide...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M908B3PubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM34233(2-Phenyl-benzo[d]isoselenazol-3-one | 2-Phenyl-ben...)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibition of human recombinant IDE expressed in Escherichia coli BL21 (DE3) cells using ATTO 655- Cys-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Trp as substra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5ZT5PubMed
TargetHistidine-rich protein PFHRP-II(Plasmodium falciparum)
Universit£ de Lille II

Curated by ChEMBL
LigandPNGBDBM50123565((7-Chloro-quinolin-4-yl)-[3-(4-{3-[(quinolin-4-ylm...)copy SMILEScopy InChI
Affinity DataIC50: 42.5nMAssay Description:In vitro inhibition of beta-hematin formationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6DDCPubMed
TargetHistidine-rich protein PFHRP-II(Plasmodium falciparum)
Universit£ de Lille II

Curated by ChEMBL
LigandPNGBDBM50123572((3-{4-[3-(Bis-quinolin-4-ylmethyl-amino)-propyl]-p...)copy SMILEScopy InChI
Affinity DataIC50: 43.4nMAssay Description:In vitro inhibition of beta-hematin formationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6DDCPubMed
TargetM1 family aminopeptidase(Plasmodium falciparum (isolate FcB1 / Columbia))
Inserm

Curated by ChEMBL
LigandPNGBDBM50197503(CHEMBL425291 | N-hydroxy-2-isobutyl-N'-(3-phenoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M908B3PubMed
TargetM1 family aminopeptidase(Plasmodium falciparum (isolate FcB1 / Columbia))
Inserm

Curated by ChEMBL
LigandPNGBDBM50197497(2-benzyl-N-hydroxy-N'-(4-phenyl-butyl)-malonamide ...)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M908B3PubMed
TargetHistidine-rich protein PFHRP-II(Plasmodium falciparum)
Universit£ de Lille II

Curated by ChEMBL
LigandPNGBDBM50123613(CHEMBL152886 | [3-(4-{3-[Bis-(4-methoxy-benzyl)-am...)copy SMILEScopy InChI
Affinity DataIC50: 47.8nMAssay Description:In vitro inhibition of beta-hematin formationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6DDCPubMed
TargetEndoplasmic reticulum aminopeptidase 2(Homo sapiens (Human))
National Center for Scientific Research Demokritos

Curated by ChEMBL
LigandPNGBDBM50076744(CHEMBL3416733)copy SMILES
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant ERAP2 (unknown origin) expressed in baculovirus infected insect cells using L-arginine-7-amido-4-methylcoumarine as substra...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Mus musculus (Mouse))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50525489(CHEMBL4556893)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of N-terminal His6-tagged mouse recombinant IDE Escherichia coli BL21 (DE3) cells using fluorogenic peptide Mca-RPPGFSAFK(Dnp)-OH as subst...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5ZT5PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50514416(CHEMBL4466030)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8C0RPubMed
TargetHistidine-rich protein PFHRP-II(Plasmodium falciparum)
Universit£ de Lille II

Curated by ChEMBL
LigandPNGBDBM50123582(CHEMBL422682 | N-(3-(4-(3-(7-chloroquinolin-4-ylam...)copy SMILEScopy InChI
Affinity DataIC50: 50.6nMAssay Description:In vitro inhibition of beta-hematin formationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6DDCPubMed
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