Compile Data Set for Download or QSAR
Found 100 with Last Name = 'gamse' and Initial = 'r'
Target5-hydroxytryptamine receptor 2A(Bovine)
Sandoz Pharma Limited

Curated by ChEMBL
LigandPNGBDBM50005836(4-Amino-5-chloro-N-{1-[3-(4-fluoro-phenoxy)-propyl...)copy SMILEScopy InChI
Affinity DataKi:  7.20nMAssay Description:Compound was evaluated for the binding affinity at 5- HT2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W959VMPubMed
TargetAlpha-2A adrenergic receptor [16-465](Rat)
Sandoz Pharma Limited

Curated by ChEMBL
LigandPNGBDBM50005836(4-Amino-5-chloro-N-{1-[3-(4-fluoro-phenoxy)-propyl...)copy SMILEScopy InChI
Affinity DataKi:  30nMAssay Description:Compound was evaluated for the binding affinity at Alpha adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W959VMPubMed
Target5-hydroxytryptamine receptor 1A(Human)
Sandoz Pharma Limited

Curated by ChEMBL
LigandPNGBDBM50031474((2E)-2-[(5-hydroxy-1H-indol-3-yl)methylene]hydrazi...)copy SMILEScopy InChI
Affinity DataKi:  63nMAssay Description:Compound was evaluated for the binding affinity at 5- HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W959VMPubMed
TargetD(2) dopamine receptor(Bovine)
Sandoz Pharma Limited

Curated by ChEMBL
LigandPNGBDBM48320(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)copy SMILEScopy InChI
Affinity DataKi:  80nMAssay Description:Compound was evaluated for the binding affinity at Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W959VMPubMed
Target5-hydroxytryptamine 1D receptor(Bovine)
SANDOZ Pharma Ltd.

Curated by PDSP Ki Database
LigandPNGBDBM50056401(2-diethylaminoethyl [2-methoxy-4-amino-5-chloro]be...)copy SMILEScopy InChI
Affinity DataKi:  2.51E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M043WMPubMed
Target5-hydroxytryptamine receptor 2C(Pig)
SANDOZ Pharma Ltd.

Curated by PDSP Ki Database
LigandPNGBDBM50056401(2-diethylaminoethyl [2-methoxy-4-amino-5-chloro]be...)copy SMILEScopy InChI
Affinity DataKi:  3.98E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M043WMPubMed
TargetAlpha-1A adrenergic receptor(Bovine)
SANDOZ Pharma Ltd.

Curated by PDSP Ki Database
LigandPNGBDBM50056401(2-diethylaminoethyl [2-methoxy-4-amino-5-chloro]be...)copy SMILEScopy InChI
Affinity DataKi:  6.31E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M043WMPubMed
TargetMu-type opioid receptor(Rat)
SANDOZ Pharma Ltd.

Curated by PDSP Ki Database
LigandPNGBDBM50056401(2-diethylaminoethyl [2-methoxy-4-amino-5-chloro]be...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M043WMPubMed
Target5-hydroxytryptamine receptor 2A(Rat)
SANDOZ Pharma Ltd.

Curated by PDSP Ki Database
LigandPNGBDBM50056401(2-diethylaminoethyl [2-methoxy-4-amino-5-chloro]be...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M043WMPubMed
TargetAlpha-2A adrenergic receptor(Bovine)
SANDOZ Pharma Ltd.

Curated by PDSP Ki Database
LigandPNGBDBM50056401(2-diethylaminoethyl [2-methoxy-4-amino-5-chloro]be...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M043WMPubMed
TargetExtracellular calcium-sensing receptor(Human)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50308093(1-[3-(2-Hydroxy-ethoxy)-benzyl]-4-(4-isopropyl-phe...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240BTPubMed
TargetExtracellular calcium-sensing receptor(Human)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50308090(1-(3-Ethoxy-4-methoxy-benzyl)-4-(4-isopropyl-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240BTPubMed
TargetExtracellular calcium-sensing receptor(Human)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50308081(4-(4-Isopropyl-phenyl)-1-(4-methyl-benzyl)-6-propa...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240BTPubMed
TargetExtracellular calcium-sensing receptor(Human)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50325523(2-(4-isopropylphenyl)-7-methoxy-1-(2-methoxyethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70G1XPubMed
TargetExtracellular calcium-sensing receptor(Human)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50308087(4-(4-Isopropyl-phenyl)-1-(3-methyl-benzyl)-6-propa...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240BTPubMed
TargetExtracellular calcium-sensing receptor(Human)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50325525(2-((2-(4-isopropylphenyl)-7-methoxy-1-(2-methoxyet...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70G1XPubMed
TargetExtracellular calcium-sensing receptor(Human)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50308103(CHEMBL590539 | N-{3-[4-(4-Isopropyl-pheny)-2-oxo-6...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240BTPubMed
TargetExtracellular calcium-sensing receptor(Human)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50308108(1-Benzyl-5-cyclopropylmethyl-6-hydroxy-4-(4-isopro...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240BTPubMed
TargetExtracellular calcium-sensing receptor(Human)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50325524(2-(4-isopropylphenyl)-7-methoxy-1-(2-methoxyethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70G1XPubMed
TargetExtracellular calcium-sensing receptor(Human)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50308089(1-(3-Methoxy-benzyl)-4-(4-isopropyl-phenyl)-6-prop...)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240BTPubMed
TargetExtracellular calcium-sensing receptor(Human)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50308091(CHEMBL597194 | {3-[4-(4-Isopropyl-phenyl)-2-oxo-6-...)copy SMILEScopy InChI
Affinity DataIC50: 3.40nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240BTPubMed
TargetExtracellular calcium-sensing receptor(Human)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50308106(5-Allyl-1-benzyl-6-hydroxy-4-(4-isopropyl-phenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240BTPubMed
TargetExtracellular calcium-sensing receptor(Human)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50325521(2-(4-isopropylphenyl)-7-methoxy-1-(2-methoxyethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70G1XPubMed
TargetExtracellular calcium-sensing receptor(Human)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50325522(4-bromo-2-(4-isopropylphenyl)-7-methoxy-1-(2-metho...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70G1XPubMed
TargetExtracellular calcium-sensing receptor(Human)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50308084(4-(4-Isopropyl-phenyl)-1-(4-methoxy-benzyl)-6-prop...)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240BTPubMed
TargetExtracellular calcium-sensing receptor(Human)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50308082(1-(4-Ethyl-benzyl)-4-(4-isopropyl-phenyl)-6-propar...)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240BTPubMed
TargetExtracellular calcium-sensing receptor(Human)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50308080(1-Benzyl-4-(4-isopropyl-phenyl)-6-propargyloxy-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 4.40nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240BTPubMed
TargetExtracellular calcium-sensing receptor(Human)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50325519(4-bromo-2-(4-isopropylphenyl)-7-methoxy-1-(2-metho...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70G1XPubMed
TargetExtracellular calcium-sensing receptor(Human)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50325515(5-benzyl-4-bromo-2-(4-isopropylphenyl)-7-methoxy-1...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70G1XPubMed
TargetExtracellular calcium-sensing receptor(Human)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50325508(5-bromo-4-iodo-2-(4-isopropylphenyl)-7-methoxy-1-(...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70G1XPubMed
TargetExtracellular calcium-sensing receptor(Human)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50308107(1-Benzyl-6-hydroxy-4-(4-isopropyl-phenyl)-5-propyl...)copy SMILEScopy InChI
Affinity DataIC50: 6.60nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240BTPubMed
TargetExtracellular calcium-sensing receptor(Human)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50308092(1-[3-(2-Hydroxy-ethoxy)-benzyl]-4-(4-isopropyl-phe...)copy SMILEScopy InChI
Affinity DataIC50: 7.30nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240BTPubMed
TargetExtracellular calcium-sensing receptor(Human)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50308105(2-[4-(3-Dimethylamino-propyl)piperazin-1-yl]-N-{3-...)copy SMILEScopy InChI
Affinity DataIC50: 8.10nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240BTPubMed
TargetExtracellular calcium-sensing receptor(Human)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50308078(1-Isopropyl-4-(4-isopropyl-phenyl)-6-propargyloxy-...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240BTPubMed
TargetExtracellular calcium-sensing receptor(Human)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50325509(4-bromo-2-(4-isopropylphenyl)-7-methoxy-1-(2-metho...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70G1XPubMed
TargetExtracellular calcium-sensing receptor(Human)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50308086(CHEMBL603248 | {4-[4-(4-Isopropyl-phenyl)-2-oxo-6-...)copy SMILEScopy InChI
Affinity DataIC50: 12.6nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240BTPubMed
TargetExtracellular calcium-sensing receptor(Human)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50308088(1-(3-Ethyl-benzyl)-4-(4-isopropyl-phenyl)-6-propar...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240BTPubMed
TargetExtracellular calcium-sensing receptor(Human)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50325498(4-iodo-2-(4-isopropylphenyl)-7-methoxy-1-(2-methox...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70G1XPubMed
TargetExtracellular calcium-sensing receptor(Human)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50308104(CHEMBL590552 | N-{3-[4-(4-Isopropyl-pheny)-2-oxo-6...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240BTPubMed
TargetExtracellular calcium-sensing receptor(Human)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50325507(4,5-dibromo-2-(4-isopropylphenyl)-7-methoxy-1-(2-m...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70G1XPubMed
TargetExtracellular calcium-sensing receptor(Human)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50325520(4-bromo-2-(4-isopropylphenyl)-7-methoxy-1-(2-metho...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70G1XPubMed
TargetExtracellular calcium-sensing receptor(Human)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50325510(5-bromo-2-(4-isopropylphenyl)-7-methoxy-1-(2-metho...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70G1XPubMed
TargetExtracellular calcium-sensing receptor(Human)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50308085(1-(4-Ethoxy-benzyl)-4-(4-isopropyl-phenyl)-6-propa...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240BTPubMed
TargetExtracellular calcium-sensing receptor(Human)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50325497(4-bromo-2-(4-isopropylphenyl)-7-methoxy-1-(2-metho...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70G1XPubMed
TargetExtracellular calcium-sensing receptor(Human)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50325511(4-bromo-2-(4-isopropylphenyl)-7-methoxy-1-(2-metho...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70G1XPubMed
TargetExtracellular calcium-sensing receptor(Human)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50325516(2-(4-isopropylphenyl)-7-methoxy-5-(2-methoxybenzyl...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70G1XPubMed
TargetExtracellular calcium-sensing receptor(Human)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50308083(1-(4-Isopropyl-benzyl)-4-(4-isopropyl-phenyl)-6-pr...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240BTPubMed
TargetExtracellular calcium-sensing receptor(Human)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50308100(6-(Propargylamino)-1-isopropyl-4-(4-isopropyl-phen...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240BTPubMed
TargetExtracellular calcium-sensing receptor(Human)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50325517(4-bromo-5-(3,4-dimethoxybenzyl)-2-(4-isopropylphen...)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70G1XPubMed
TargetExtracellular calcium-sensing receptor(Human)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50325496(4-chloro-2-(4-isopropylphenyl)-7-methoxy-1-(2-meth...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70G1XPubMed
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