Compile Data Set for Download or QSAR
Found 126 with Last Name = 'jiao' and Initial = 'r'
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50269378(CHEMBL447311 | apigenin-4'-O-(2''-O-p-coumaroyl)-b...)copy SMILEScopy InChI
Affinity DataKi:  1.44E+4nMAssay Description:Inhibition of xanthine oxidase (unknown origin) by competitive Lineweaver-burk plotMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NG6PubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257994((1S,3R)-N-(3,5-bis(-trifluoromethyl)benzyl)-1-iso ...)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells by chemotaxis assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257994((1S,3R)-N-(3,5-bis(-trifluoromethyl)benzyl)-1-iso ...)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells by chemotaxis assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257994((1S,3R)-N-(3,5-bis(-trifluoromethyl)benzyl)-1-iso ...)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells by chemotaxis assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212136((1S,3R)-N-{[3-fluoro-5-(trifluoromethyl)phenyl]met...)copy SMILEScopy InChI
Affinity DataIC50: 0.150nMAssay Description:Inhibition of chemotaxis in human MCP1 monocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3CN8PubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212127((1S,3R)-1-cyclopropyl-N-{[3-fluoro-5-(trifluoromet...)copy SMILEScopy InChI
Affinity DataIC50: 0.230nMAssay Description:Inhibition of chemotaxis in human MCP1 monocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3CN8PubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257995((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-3-(3-et...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells by chemotaxis assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212128((1R,3R)-N-{[3-fluoro-5-(trifluoromethyl)phenyl]met...)copy SMILEScopy InChI
Affinity DataIC50: 0.320nMAssay Description:Inhibition of chemotaxis in human MCP1 monocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3CN8PubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212127((1S,3R)-1-cyclopropyl-N-{[3-fluoro-5-(trifluoromet...)copy SMILEScopy InChI
Affinity DataIC50: 0.630nMAssay Description:Inhibition of Ca2+ flux in human monocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3CN8PubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212136((1S,3R)-N-{[3-fluoro-5-(trifluoromethyl)phenyl]met...)copy SMILEScopy InChI
Affinity DataIC50: 0.710nMAssay Description:Inhibition of Ca2+ flux in human monocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3CN8PubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258046((1S,3R)-N-(3,5-bis(trifluoromethyl)benz yl)-3-(3-f...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells by chemotaxis assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258046((1S,3R)-N-(3,5-bis(trifluoromethyl)benz yl)-3-(3-f...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells by chemotaxis assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258090((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-isopr...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells by chemotaxis assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50211499((1S,3R)-N-[3,5-bis(trifluoromethyl)benzyl]-1-methy...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Displacement of [125]hMCP1 from human CCR2 receptor expressed in human monocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7HCFPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50088301((E)-N,N-dimethyl-N-(4-(2-p-tolyl-6,7-dihydro-5H-be...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of CCR5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50211497((1S,3R)-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Displacement of [125]hMCP1 from human CCR2 receptor expressed in human monocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7HCFPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257994((1S,3R)-N-(3,5-bis(-trifluoromethyl)benzyl)-1-iso ...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257994((1S,3R)-N-(3,5-bis(-trifluoromethyl)benzyl)-1-iso ...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212127((1S,3R)-1-cyclopropyl-N-{[3-fluoro-5-(trifluoromet...)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Displacement of [125I]MCP1 from human CCR2 I40L mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3CN8PubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212128((1R,3R)-N-{[3-fluoro-5-(trifluoromethyl)phenyl]met...)copy SMILEScopy InChI
Affinity DataIC50: 2.04nMAssay Description:Inhibition of Ca2+ flux in human monocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3CN8PubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50211497((1S,3R)-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}...)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Antagonist activity against human CCR2 receptor assessed as inhibition of MCP1-induced calcium flux in human monocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7HCFPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257995((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-3-(3-et...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257995((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-3-(3-et...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257995((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-3-(3-et...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212136((1S,3R)-N-{[3-fluoro-5-(trifluoromethyl)phenyl]met...)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMAssay Description:Displacement of [125I]MCP1 from human CCR2 I40L mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3CN8PubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212146(1-ethyl-N-{[3-fluoro-5-(trifluoromethyl)phenyl]met...)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Displacement of [125I]MCP1 from human CCR2 I40L mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3CN8PubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257841((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-isopr...)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells by chemotaxis assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212146(1-ethyl-N-{[3-fluoro-5-(trifluoromethyl)phenyl]met...)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3CN8PubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212122((1R,3R)-N-{[3-fluoro-5-(trifluoromethyl)phenyl]met...)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Displacement of [125I]MCP1 from human CCR2 I40L mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3CN8PubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212128((1R,3R)-N-{[3-fluoro-5-(trifluoromethyl)phenyl]met...)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMAssay Description:Displacement of [125I]MCP1 from human CCR2 I40L mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3CN8PubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257994((1S,3R)-N-(3,5-bis(-trifluoromethyl)benzyl)-1-iso ...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212140((1S,3R)-N-{[3-fluoro-5-(trifluoromethyl)phenyl]met...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Displacement of [125I]MCP1 from human CCR2 I40L mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3CN8PubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257898((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-isopr...)copy SMILEScopy InChI
Affinity DataIC50: 4.60nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212134(CHEMBL231038 | N-{[3-fluoro-5-(trifluoromethyl)phe...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Displacement of [125I]MCP1 from human CCR2 I40L mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3CN8PubMed
TargetC-C chemokine receptor type 2(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212136((1S,3R)-N-{[3-fluoro-5-(trifluoromethyl)phenyl]met...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3CN8PubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258043((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-isopr...)copy SMILEScopy InChI
Affinity DataIC50: 5.10nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells by chemotaxis assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258090((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-isopr...)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212131(1-(cyclopropylmethyl)-N-{[3-fluoro-5-(trifluoromet...)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:Displacement of [125I]MCP1 from human CCR2 I40L mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3CN8PubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258046((1S,3R)-N-(3,5-bis(trifluoromethyl)benz yl)-3-(3-f...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212135(CHEMBL266017 | N-{[3,5-bis(trifluoromethyl)phenyl]...)copy SMILEScopy InChI
Affinity DataIC50: 6.5nMAssay Description:Displacement of [125I]MCP1 from human CCR2 I40L mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3CN8PubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258143((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-3-(3,5-...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212128((1R,3R)-N-{[3-fluoro-5-(trifluoromethyl)phenyl]met...)copy SMILEScopy InChI
Affinity DataIC50: 7.5nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3CN8PubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50211502((1S,3R)-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}...)copy SMILEScopy InChI
Affinity DataIC50: 7.5nMAssay Description:Displacement of [125]hMCP1 from human CCR2 receptor expressed in human monocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7HCFPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212145((1S,3R)-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}...)copy SMILEScopy InChI
Affinity DataIC50: 7.60nMAssay Description:Displacement of [125I]MCP1 from human CCR2 I40L mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3CN8PubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258043((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-isopr...)copy SMILEScopy InChI
Affinity DataIC50: 7.80nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212139((1R,3R)-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Displacement of [125I]MCP1 from human CCR2 I40L mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3CN8PubMed
TargetC-C chemokine receptor type 2(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212127((1S,3R)-1-cyclopropyl-N-{[3-fluoro-5-(trifluoromet...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3CN8PubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212125(CHEMBL389610 | N-{[3-fluoro-5-(trifluoromethyl)phe...)copy SMILEScopy InChI
Affinity DataIC50: 8.5nMAssay Description:Displacement of [125I]MCP1 from human CCR2 I40L mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3CN8PubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257841((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-isopr...)copy SMILEScopy InChI
Affinity DataIC50: 8.60nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257841((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-isopr...)copy SMILEScopy InChI
Affinity DataIC50: 8.60nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
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