Compile Data Set for Download or QSAR
Found 40 with Last Name = 'löser' and Initial = 'r'
TargetPapain(Carica papaya)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50304793((S)-benzyl 1-(2-cyano-1,2-dimethylhydrazinyl)-1-ox...)copy SMILEScopy InChI
Affinity DataKi:  3.90nMAssay Description:Inhibition of Carica papaya papain by microtiter plate spectrofluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X57WMPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50084235(2-Diethylamino-benzo[4,5]thieno[2,3-d][1,3]oxazin-...)copy SMILEScopy InChI
Affinity DataKi:  5.80nMAssay Description:Inhibitory activity of the compound was tested against human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K936RGPubMed
TargetPapain(Carica papaya)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50304796((S)-benzyl 1-(2-cyano-1-methyl-2-phenethylhydrazin...)copy SMILEScopy InChI
Affinity DataKi:  6.30nMAssay Description:Inhibition of Carica papaya papain by microtiter plate spectrofluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X57WMPubMed
TargetPapain(Carica papaya)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50304794((S)-benzyl 1-(2-cyano-1,2-dimethylhydrazinyl)-4-me...)copy SMILEScopy InChI
Affinity DataKi:  8.20nMAssay Description:Inhibition of Carica papaya papain by microtiter plate spectrofluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X57WMPubMed
TargetPapain(Carica papaya)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50304797((S)-benzyl 1-(2-cyano-1-methyl-2-pentylhydrazinyl)...)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Inhibition of Carica papaya papain by microtiter plate spectrofluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X57WMPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50064308(2-Diethylamino-5,6,7,8-tetrahydro-benzo[4,5]thieno...)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:Inhibitory activity of the compound was tested against human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K936RGPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50084232(2-(diethylamino)-5-isopropyl-4H-thieno[2,3-d][1,3]...)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:Inhibitory activity of the compound was tested against human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K936RGPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50084233(2-Diethylamino-6,7-dihydro-5H-cyclopenta[4,5]thien...)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:Inhibitory activity of the compound was tested against human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K936RGPubMed
TargetPapain(Carica papaya)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50304795((S)-benzyl 1-(2-benzyl-2-cyano-1-methylhydrazinyl)...)copy SMILEScopy InChI
Affinity DataKi:  42nMAssay Description:Inhibition of Carica papaya papain by microtiter plate spectrofluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X57WMPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50084234(2-Diethylamino-6,7,8,9-tetrahydro-5H-3-oxa-10-thia...)copy SMILEScopy InChI
Affinity DataKi:  44nMAssay Description:Inhibitory activity of the compound was tested against human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K936RGPubMed
TargetCaspase-1(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50308243((S)-3-((S)-2-((S)-2-(2-naphthamido)-3-methylbutana...)copy SMILEScopy InChI
Affinity DataKi:  47nMAssay Description:Inhibition of human recombinant caspase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8FNSPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50084227(2-(diethylamino)-5-methyl-4-oxo-4H-thieno[2,3-d][1...)copy SMILEScopy InChI
Affinity DataKi:  91nMAssay Description:Inhibitory activity of the compound was tested against human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K936RGPubMed
TargetCaspase-1(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50308235((S)-3-((S)-2-((S)-2-(2-naphthamido)-3-methylbutana...)copy SMILEScopy InChI
Affinity DataKi:  128nMAssay Description:Inhibition of human recombinant caspase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8FNSPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50084230(2-Diethylamino-thieno[3,2-d][1,3]oxazin-4-one | CH...)copy SMILEScopy InChI
Affinity DataKi:  130nMAssay Description:Inhibitory activity of the compound was tested against human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K936RGPubMed
TargetCaspase-1(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50308238((S)-3-((S)-2-((S)-2-(2-naphthamido)-3-methylbutana...)copy SMILEScopy InChI
Affinity DataKi:  209nMAssay Description:Inhibition of human recombinant caspase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8FNSPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50084229(2-Diethylamino-5-methyl-5,6,7,8-tetrahydro-benzo[4...)copy SMILEScopy InChI
Affinity DataKi:  210nMAssay Description:Inhibitory activity of the compound was tested against human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K936RGPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50084236(2-Diethylamino-thieno[2,3-d][1,3]oxazin-4-one | CH...)copy SMILEScopy InChI
Affinity DataKi:  260nMAssay Description:Inhibitory activity of the compound was tested against human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K936RGPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50084231(2-Diethylamino-benzo[d][1,3]oxazin-4-one | CHEMBL3...)copy SMILEScopy InChI
Affinity DataKi:  310nMAssay Description:Inhibitory activity of the compound was tested against human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K936RGPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50084228(2-(diethylamino)-5-methyl-4H-thieno[2,3-d][1,3]oxa...)copy SMILEScopy InChI
Affinity DataKi:  450nMAssay Description:Inhibitory activity of the compound was tested against human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K936RGPubMed
TargetCaspase-1(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50308233((S)-3-((S)-2-((S)-2-(2-naphthamido)-3-methylbutana...)copy SMILEScopy InChI
Affinity DataKi:  600nMAssay Description:Inhibition of human recombinant caspase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8FNSPubMed
TargetCaspase-1(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50308237((S)-3-((S)-2-((S)-2-(2-naphthamido)-3-methylbutana...)copy SMILEScopy InChI
Affinity DataKi:  945nMAssay Description:Inhibition of human recombinant caspase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8FNSPubMed
TargetCaspase-1(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50308241((S)-3-((S)-2-((S)-2-(2-naphthamido)-3-methylbutana...)copy SMILEScopy InChI
Affinity DataKi:  965nMAssay Description:Inhibition of human recombinant caspase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8FNSPubMed
TargetCaspase-1(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50308242((S)-3-((S)-2-((S)-2-(2-naphthamido)-3-methylbutana...)copy SMILEScopy InChI
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of human recombinant caspase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8FNSPubMed
TargetCaspase-1(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50308240((S)-3-((S)-2-((S)-2-(2-naphthamido)-3-methylbutana...)copy SMILEScopy InChI
Affinity DataKi:  1.37E+3nMAssay Description:Inhibition of human recombinant caspase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8FNSPubMed
TargetCaspase-1(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50308239((S)-3-((S)-2-((S)-2-(2-naphthamido)-3-methylbutana...)copy SMILEScopy InChI
Affinity DataKi:  1.82E+3nMAssay Description:Inhibition of human recombinant caspase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8FNSPubMed
TargetCaspase-1(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50308236((S)-3-((S)-2-((S)-2-(2-naphthamido)-3-methylbutana...)copy SMILEScopy InChI
Affinity DataKi:  1.89E+3nMAssay Description:Inhibition of human recombinant caspase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8FNSPubMed
TargetPapain(Carica papaya)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50304798(CHEMBL595637 | benzyl(S)-1-((S)-1-cyanoethylamino)...)copy SMILEScopy InChI
Affinity DataKi:  2.20E+3nMAssay Description:Inhibition of Carica papaya papain by microtiter plate spectrofluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X57WMPubMed
TargetCaspase-1(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50308234((R)-3-((S)-2-((S)-2-(2-naphthamido)-3-methylbutana...)copy SMILEScopy InChI
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human recombinant caspase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8FNSPubMed
TargetPapain(Carica papaya)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50304799(CHEMBL603537 | benzyl(S)-1-(((S)-1-cyanoethyl)(met...)copy SMILEScopy InChI
Affinity DataKi:  7.50E+5nMAssay Description:Inhibition of Carica papaya papain by microtiter plate spectrofluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X57WMPubMed
TargetCaspase-1(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50308244((S)-3-((S)-2-((S)-2-(2-naphthamido)-3-methylbutana...)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human recombinant caspase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8FNSPubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50444514(CHEMBL3092843)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human TGase2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64KJPPubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50444513(CHEMBL3092841)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of human TGase2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64KJPPubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50444512(CHEMBL3092842)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Inhibition of human TGase2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64KJPPubMed
TargetProtein-glutamine gamma-glutamyltransferase K(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50444512(CHEMBL3092842)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Inhibition of human TGase1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64KJPPubMed
TargetCoagulation factor XIII A chain(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50444513(CHEMBL3092841)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of factor13a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64KJPPubMed
TargetCoagulation factor XIII A chain(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50444514(CHEMBL3092843)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of factor13a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64KJPPubMed
TargetCoagulation factor XIII A chain(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50444512(CHEMBL3092842)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of factor13a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64KJPPubMed
TargetCaspase-8(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50308243((S)-3-((S)-2-((S)-2-(2-naphthamido)-3-methylbutana...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of caspase 8More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8FNSPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50084228(2-(diethylamino)-5-methyl-4H-thieno[2,3-d][1,3]oxa...)copy SMILEScopy InChI
Affinity DataKd:  5.50E+3nMAssay Description:Inhibitory activity of the compound was tested against human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K936RGPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50084227(2-(diethylamino)-5-methyl-4-oxo-4H-thieno[2,3-d][1...)copy SMILEScopy InChI
Affinity DataKd:  620nMAssay Description:Inhibitory activity of the compound was tested against human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K936RGPubMed