Compile Data Set for Download or QSAR
Found 88 with Last Name = 'leiva' and Initial = 'r'
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50525808(CHEMBL4454212)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of recombinant human liver soluble epoxide hydrolase expressed in baculovirus infected Sf21 cells using NEPC as substrate by fluorescence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668HMVPubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50351248(CHEMBL1818384)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of recombinant human liver soluble epoxide hydrolase expressed in baculovirus infected Sf21 cells using NEPC as substrate by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668HMVPubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50351247(CHEMBL1818385)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of recombinant human liver soluble epoxide hydrolase expressed in baculovirus infected Sf21 cells using NEPC as substrate by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668HMVPubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50525805(CHEMBL4448782)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant human liver soluble epoxide hydrolase expressed in baculovirus infected Sf21 cells using NEPC as substrate by fluorescence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668HMVPubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50217448(CHEMBL242459 | US9029401, 1471 (t-AUCB) | trans-4-...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant human soluble epoxide hydrolase using CMNPC as substrate preincubated for 5 mins followed by substrate addition and measure...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50525798(CHEMBL4535555)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant human liver soluble epoxide hydrolase expressed in baculovirus infected Sf21 cells using NEPC as substrate by fluorescence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668HMVPubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50217448(CHEMBL242459 | US9029401, 1471 (t-AUCB) | trans-4-...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant human liver soluble epoxide hydrolase expressed in baculovirus infected Sf21 cells using NEPC as substrate by fluorescence ...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50525803(CHEMBL4467051)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of murine soluble epoxide hydrolase expressed in baculovirus infected Sf21 cells using NEPC as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668HMVPubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)TBA
LigandPNGBDBM50560757(CHEMBL4784283)copy SMILES
Affinity DataIC50: 1.90nMAssay Description:Inhibition of recombinant rat soluble epoxide hydrolase using CMNPC as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4TCDPubMed
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50191854(CHEMBL436774 | N-(1-acetyl-piperidin-4-yl)-N'-(ada...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of murine soluble epoxide hydrolase expressed in baculovirus infected Sf21 cells using NEPC as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668HMVPubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50525799(CHEMBL4448746)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of recombinant human liver soluble epoxide hydrolase expressed in baculovirus infected Sf21 cells using NEPC as substrate by fluorescence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668HMVPubMed
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50525804(CHEMBL4516638)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Inhibition of murine soluble epoxide hydrolase expressed in baculovirus infected Sf21 cells using NEPC as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668HMVPubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)TBA
LigandPNGBDBM50560743(CHEMBL4759592)copy SMILES
Affinity DataIC50: 3.30nMAssay Description:Inhibition of recombinant rat soluble epoxide hydrolase using CMNPC as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4TCDPubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50525806(CHEMBL4458692)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Inhibition of recombinant human liver soluble epoxide hydrolase expressed in baculovirus infected Sf21 cells using NEPC as substrate by fluorescence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668HMVPubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50525802(CHEMBL4530604)copy SMILEScopy InChI
Affinity DataIC50: 3.40nMAssay Description:Inhibition of recombinant human liver soluble epoxide hydrolase expressed in baculovirus infected Sf21 cells using NEPC as substrate by fluorescence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668HMVPubMed
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50525802(CHEMBL4530604)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of murine soluble epoxide hydrolase expressed in baculovirus infected Sf21 cells using NEPC as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668HMVPubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50525804(CHEMBL4516638)copy SMILEScopy InChI
Affinity DataIC50: 6.5nMAssay Description:Inhibition of recombinant human liver soluble epoxide hydrolase expressed in baculovirus infected Sf21 cells using NEPC as substrate by fluorescence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668HMVPubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50525803(CHEMBL4467051)copy SMILEScopy InChI
Affinity DataIC50: 7.20nMAssay Description:Inhibition of recombinant human liver soluble epoxide hydrolase expressed in baculovirus infected Sf21 cells using NEPC as substrate by fluorescence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668HMVPubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50351247(CHEMBL1818385)copy SMILEScopy InChI
Affinity DataIC50: 7.70nMAssay Description:Inhibition of recombinant human soluble epoxide hydrolase using CMNPC as substrate preincubated for 5 mins followed by substrate addition and measure...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4TCDPubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50191854(CHEMBL436774 | N-(1-acetyl-piperidin-4-yl)-N'-(ada...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human soluble epoxide hydrolase using CMNPC as substrate preincubated for 5 mins followed by substrate addition and measure...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4TCDPubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50191854(CHEMBL436774 | N-(1-acetyl-piperidin-4-yl)-N'-(ada...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human liver soluble epoxide hydrolase expressed in baculovirus infected Sf21 cells using NEPC as substrate by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668HMVPubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50525800(CHEMBL4463408)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human liver soluble epoxide hydrolase expressed in baculovirus infected Sf21 cells using NEPC as substrate by fluorescence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668HMVPubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50525801(CHEMBL4465856)copy SMILEScopy InChI
Affinity DataIC50: 8.60nMAssay Description:Inhibition of recombinant human liver soluble epoxide hydrolase expressed in baculovirus infected Sf21 cells using NEPC as substrate by fluorescence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668HMVPubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50560744(CHEMBL4779073)copy SMILES
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant human soluble epoxide hydrolase using CMNPC as substrate preincubated for 5 mins followed by substrate addition and measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4TCDPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50277197(CHEMBL4170544)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using [3H]cortisone as substrate preincubated for 15 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2D5RPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50277203(CHEMBL4170932)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using [3H]cortisone as substrate preincubated for 15 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2D5RPubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50560750(CHEMBL4778324)copy SMILES
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human soluble epoxide hydrolase using CMNPC as substrate preincubated for 5 mins followed by substrate addition and measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4TCDPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50277198(CHEMBL4163698)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using [3H]cortisone as substrate preincubated for 15 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2D5RPubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50560745(CHEMBL4797443)copy SMILES
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant human soluble epoxide hydrolase using CMNPC as substrate preincubated for 5 mins followed by substrate addition and measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4TCDPubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50525807(CHEMBL4447946)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant human liver soluble epoxide hydrolase expressed in baculovirus infected Sf21 cells using NEPC as substrate by fluorescence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668HMVPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50277179(CHEMBL4160328)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using [3H]cortisone as substrate preincubated for 15 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2D5RPubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50560743(CHEMBL4759592)copy SMILES
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human soluble epoxide hydrolase using CMNPC as substrate preincubated for 5 mins followed by substrate addition and measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4TCDPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50277178(CHEMBL4162610)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using [3H]cortisone as substrate preincubated for 15 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2D5RPubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50560751(CHEMBL4750570)copy SMILES
Affinity DataIC50: 36nMAssay Description:Inhibition of recombinant human soluble epoxide hydrolase using CMNPC as substrate preincubated for 5 mins followed by substrate addition and measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4TCDPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50277199(CHEMBL4168636)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using [3H]cortisone as substrate preincubated for 15 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2D5RPubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50560756(CHEMBL4784603)copy SMILES
Affinity DataIC50: 46nMAssay Description:Inhibition of recombinant human soluble epoxide hydrolase using CMNPC as substrate preincubated for 5 mins followed by substrate addition and measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4TCDPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50277206(CHEMBL4174155)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using [3H]cortisone as substrate preincubated for 15 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2D5RPubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50560749(CHEMBL4762265)copy SMILES
Affinity DataIC50: 53nMAssay Description:Inhibition of recombinant human soluble epoxide hydrolase using CMNPC as substrate preincubated for 5 mins followed by substrate addition and measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4TCDPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50120378(CHEMBL3616709)copy SMILEScopy InChI
Affinity DataIC50: 74nMAssay Description:Inhibition of 11beta-HSD1 in human mixed sex human liver microsomes assessed as reduction in conversion of [3H]-cortisone to [3H]-cortisol pre-incuba...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP47Z5PubMed
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50560756(CHEMBL4784603)copy SMILES
Affinity DataIC50: 76nMAssay Description:Inhibition of recombinant mouse soluble epoxide hydrolase using CMNPC as substrate preincubated for 5 mins followed by substrate addition and measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4TCDPubMed
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50560757(CHEMBL4784283)copy SMILES
Affinity DataIC50: 79nMAssay Description:Inhibition of recombinant mouse soluble epoxide hydrolase using CMNPC as substrate preincubated for 5 mins followed by substrate addition and measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4TCDPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50277178(CHEMBL4162610)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of 11beta-HSD1 in CD1 mouse liver microsomes using cortisone as substrate preincubated for 15 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2D5RPubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50560760(CHEMBL4753341)copy SMILES
Affinity DataIC50: 83nMAssay Description:Inhibition of recombinant human soluble epoxide hydrolase using CMNPC as substrate preincubated for 5 mins followed by substrate addition and measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4TCDPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50120377(CHEMBL1889797)copy SMILEScopy InChI
Affinity DataIC50: 86nMAssay Description:Inhibition of 11beta-HSD1 in human mixed sex human liver microsomes assessed as reduction in conversion of [3H]-cortisone to [3H]-cortisol pre-incuba...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP47Z5PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50277202(CHEMBL4174368)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using [3H]cortisone as substrate preincubated for 15 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2D5RPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50317209((2R)-N-(adamantan-2-yl)-1-ethylpyrrolidine-2-carbo...)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using [3H]cortisone as substrate preincubated for 15 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2D5RPubMed
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50560743(CHEMBL4759592)copy SMILES
Affinity DataIC50: 92nMAssay Description:Inhibition of recombinant mouse soluble epoxide hydrolase using CMNPC as substrate preincubated for 5 mins followed by substrate addition and measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4TCDPubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50277179(CHEMBL4160328)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of human full-length 11beta-HSD2 expressed in HEK293 cells using cortisol as substrate after 2 hrs by LC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2D5RPubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50277198(CHEMBL4163698)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of human full-length 11beta-HSD2 expressed in HEK293 cells using cortisol as substrate after 2 hrs by LC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2D5RPubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50277202(CHEMBL4174368)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of human full-length 11beta-HSD2 expressed in HEK293 cells using cortisol as substrate after 2 hrs by LC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2D5RPubMed
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