Compile Data Set for Download or QSAR
Found 104 with Last Name = 'ovadia' and Initial = 'r'
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048WPPubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048WPPubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 6a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048WPPubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 3a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048WPPubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 3a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048WPPubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 6a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048WPPubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1b infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048WPPubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1b infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048WPPubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 4a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048WPPubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 4a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048WPPubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50333129(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1...)copy SMILEScopy InChI
Affinity DataIC50: 96nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048WPPubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50333129(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1...)copy SMILEScopy InChI
Affinity DataIC50: 96nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048WPPubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)copy SMILEScopy InChI
Affinity DataIC50: 97nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 5a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048WPPubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)copy SMILEScopy InChI
Affinity DataIC50: 97nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 5a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048WPPubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50333129(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 6a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048WPPubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50333129(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 6a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048WPPubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50333129(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1b infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048WPPubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50333129(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1b infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048WPPubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 2a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048WPPubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 2a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048WPPubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50333129(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1...)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 2a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048WPPubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50333129(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1...)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 2a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048WPPubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50333129(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1...)copy SMILEScopy InChI
Affinity DataIC50: 380nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 3a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048WPPubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50333129(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1...)copy SMILEScopy InChI
Affinity DataIC50: 380nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 3a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048WPPubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50333129(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1...)copy SMILEScopy InChI
Affinity DataIC50: 430nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 5a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048WPPubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50333129(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1...)copy SMILEScopy InChI
Affinity DataIC50: 430nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 5a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048WPPubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50333129(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1...)copy SMILEScopy InChI
Affinity DataIC50: 570nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 4a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048WPPubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50333129(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1...)copy SMILEScopy InChI
Affinity DataIC50: 570nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 4a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048WPPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50020712(10,11-dihydro-5-(gamma-dimethylaminopropylidene)-5...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells at -80 mV holding potential by whole-cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048WPPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50020712(10,11-dihydro-5-(gamma-dimethylaminopropylidene)-5...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells at -80 mV holding potential by whole-cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048WPPubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50090910(3alpha,16,17,18-tetrahydroxyaphidicolone | 6,13-di...)copy SMILEScopy InChI
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of human DNA polymerase alpha using 5-end radiolabeled 24nt to 48nt DNA as primer template after 5 mins in presence of dCTP/dGTP/dTTP/dATP...More data for this Ligand-Target Pair
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50090910(3alpha,16,17,18-tetrahydroxyaphidicolone | 6,13-di...)copy SMILEScopy InChI
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of human DNA polymerase alpha using 5-end radiolabeled 24nt to 48nt DNA as primer template after 5 mins in presence of dCTP/dGTP/dTTP/dATP...More data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50333129(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1...)copy SMILEScopy InChI
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of NS5B polymerase S282T mutant in HCV genotype 1b infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048WPPubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50333129(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1...)copy SMILEScopy InChI
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of NS5B polymerase S282T mutant in HCV genotype 1b infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048WPPubMed
TargetDNA polymerase beta(Homo sapiens (Human))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50164644(2',3'-Dideoxyadenosine Triphosphate (Ddatp) | 2',3...)copy SMILEScopy InChI
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of human DNA polymerase beta using 5-end radiolabeled 24nt to 48nt DNA as primer template after 5 mins in presence of dCTP/dGTP/dTTP/dATP ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048WPPubMed
TargetDNA polymerase beta(Homo sapiens (Human))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50164644(2',3'-Dideoxyadenosine Triphosphate (Ddatp) | 2',3...)copy SMILEScopy InChI
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of human DNA polymerase beta using 5-end radiolabeled 24nt to 48nt DNA as primer template after 5 mins in presence of dCTP/dGTP/dTTP/dATP ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048WPPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50530020(CHEMBL4469773)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells at -80 mV holding potential by whole-cell patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048WPPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50530019(CHEMBL4455349)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells at -80 mV holding potential by whole-cell patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048WPPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50530019(CHEMBL4455349)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells at -80 mV holding potential by whole-cell patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048WPPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50530020(CHEMBL4469773)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells at -80 mV holding potential by whole-cell patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048WPPubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of NS5B polymerase S282T mutant in HCV genotype 1b infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048WPPubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of NS5B polymerase S282T mutant in HCV genotype 1b infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048WPPubMed
TargetDNA polymerase beta(Homo sapiens (Human))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50333129(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human DNA polymerase beta using 5-end radiolabeled 24nt to 48nt DNA as primer template after 5 mins in presence of dCTP/dGTP/dTTP/dATP ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048WPPubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50333129(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human DNA polymerase alpha using 5-end radiolabeled 24nt to 48nt DNA as primer template after 5 mins in presence of dCTP/dGTP/dTTP/dATP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048WPPubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50333129(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human DNA polymerase alpha using 5-end radiolabeled 24nt to 48nt DNA as primer template after 5 mins in presence of dCTP/dGTP/dTTP/dATP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048WPPubMed
TargetDNA polymerase beta(Homo sapiens (Human))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50333129(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human DNA polymerase beta using 5-end radiolabeled 24nt to 48nt DNA as primer template after 5 mins in presence of dCTP/dGTP/dTTP/dATP ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048WPPubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50530019(CHEMBL4455349)copy SMILEScopy InChI
Affinity DataEC50:  180nMAssay Description:Inhibition of NS5B polymerase S282T mutant in HCV genotype 1b infected in human Huh7 replicon cells after 5 days by RT-PCR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048WPPubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50239940(CHEBI:85083 | PSI-7977, GS-7977 | Sofosbuvir | Sov...)copy SMILEScopy InChI
Affinity DataEC50:  44nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1b/5a chimeric replicon infected in human HuH7 replicon cells after 5 days by RT-PCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048WPPubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50530020(CHEMBL4469773)copy SMILEScopy InChI
Affinity DataEC50:  160nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 2a infected in human HuH7 replicon cells after 5 days by RT-PCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048WPPubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50530021(CHEMBL4462484)copy SMILEScopy InChI
Affinity DataEC50:  500nMAssay Description:Inhibition of NS5B polymerase in wild type HCV genotype 1b infected in human Huh7 replicon cells after 5 days by RT-PCR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048WPPubMed
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