Compile Data Set for Download or QSAR
Found 75 with Last Name = 'patti' and Initial = 'r'
TargetInterleukin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50575333(CHEMBL4857063)copy SMILES
Affinity DataIC50: 8nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
TargetInterleukin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50575331(CHEMBL4868242)copy SMILES
Affinity DataIC50: 11nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
TargetInterleukin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50575332(CHEMBL4869725)copy SMILES
Affinity DataIC50: 14nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
TargetInterleukin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50575328(CHEMBL4868367)copy SMILES
Affinity DataIC50: 32nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
TargetInterleukin-2(Homo sapiens (Human))TBA
LigandPNGBDBM387265(2,6- Difluoro-N-(2′- methyl-5′-(4-meth...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
TargetInterleukin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50575327(CHEMBL4848840)copy SMILES
Affinity DataIC50: 34nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
TargetInterleukin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50575326(CHEMBL4868517)copy SMILES
Affinity DataIC50: 50nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
TargetInterleukin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50575329(CHEMBL4859192)copy SMILES
Affinity DataIC50: 55nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
TargetInterleukin-2(Homo sapiens (Human))TBA
LigandPNGBDBM387270(2,6- Difluoro-N-(5-(2- methyl-5-(4- methyl-5-oxo-4...)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
TargetInterleukin-2(Homo sapiens (Human))TBA
LigandPNGBDBM387269(2- Chloro-N-(5-(5-(5,5- dimethyl-4-oxo-4,5- dihydr...)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
TargetInterleukin-2(Homo sapiens (Human))TBA
LigandPNGBDBM387261(N-(5′- (5,5-Dimethyl-4-oxo- 4,5-dihydroisoxa...)copy SMILEScopy InChI
Affinity DataIC50: 69nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
LigandPNGBDBM50575331(CHEMBL4868242)copy SMILES
Affinity DataIC50: 76nMAssay Description:Inhibition of Orai1/STIM1 (unknown origin) expressed in HEK293 cells assessed as reduction in Ca2+-release activated Ca2+ entry current by manual pat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
TargetInterleukin-2(Homo sapiens (Human))TBA
LigandPNGBDBM387266(N-(5′- (4-Ethyl-5-oxo-4,5- dihydro-1,3,4- ...)copy SMILEScopy InChI
Affinity DataIC50: 78nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
TargetInterleukin-2(Homo sapiens (Human))TBA
LigandPNGBDBM387272(N-(5-(5- (5,5-dimethyl-4-oxo- 4,5-dihydroisoxazol-...)copy SMILEScopy InChI
Affinity DataIC50: 94nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
LigandPNGBDBM50575336(CHEMBL4753998)copy SMILES
Affinity DataIC50: 119nMAssay Description:Inhibition of Orai1/STIM1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
TargetInterleukin-2(Homo sapiens (Human))TBA
LigandPNGBDBM387297(US10292981, Example 121)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
TargetInterleukin-2(Homo sapiens (Human))TBA
LigandPNGBDBM387294(US10292981, Example 78)copy SMILEScopy InChI
Affinity DataIC50: 171nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
TargetInterleukin-2(Homo sapiens (Human))TBA
LigandPNGBDBM387281(N-(5-(5- (5,5-Dimethyl-4-oxo- 4,5-dihydroisoxazol-...)copy SMILEScopy InChI
Affinity DataIC50: 178nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
TargetInterleukin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50575331(CHEMBL4868242)copy SMILES
Affinity DataIC50: 183nMAssay Description:Inhibition of IL2 in thapsigargin stimulated human whole bloodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Temple University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50326075((E)-4-(3-(4-Fluoro-3-nitrophenyl)-2-(4-(trifluorom...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z44N8PubMed
TargetInterleukin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50575330(CHEMBL4872805)copy SMILES
Affinity DataIC50: 227nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
TargetInterleukin-2(Homo sapiens (Human))TBA
LigandPNGBDBM387290(N-(5- (5,5-Dimethyl-4,5- dihydroisoxazol-3- yl)-2-...)copy SMILEScopy InChI
Affinity DataIC50: 328nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Temple University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50326090((E)-2-(4-Bromobenzylthio)-3-(4-fluoro-3-nitropheny...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z44N8PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Temple University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50326091((E)-4-(2-(4-Bromobenzylthio)-3-(4-fluoro-3-nitroph...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z44N8PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Temple University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50326061((E)-4-(2-(4-Bromobenzylthio)-3-(4-fluoro-3-nitroph...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z44N8PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Temple University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50326092((E)-3-(4-Fluoro-3-nitrophenyl)-2-(4-fluorobenzylth...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z44N8PubMed
TargetTumor necrosis factor(Homo sapiens (Human))TBA
LigandPNGBDBM50575331(CHEMBL4868242)copy SMILES
Affinity DataIC50: 695nMAssay Description:Inhibition of TNF-alpha in thapsigargin stimulated human whole bloodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Temple University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50326061((E)-4-(2-(4-Bromobenzylthio)-3-(4-fluoro-3-nitroph...)copy SMILEScopy InChI
Affinity DataIC50: 750nMAssay Description:Inhibition of Bcr-Abl after 20 mins by autoradiographyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z44N8PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Temple University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50326076((E)-methyl 4-(2-(4-bromobenzylthio)-3-(4-fluoro-3-...)copy SMILEScopy InChI
Affinity DataIC50: 750nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z44N8PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Temple University School of Medicine

Curated by ChEMBL
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataIC50: 750nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
LigandPNGBDBM50575336(CHEMBL4753998)copy SMILES
Affinity DataIC50: 895nMAssay Description:Inhibition of Orai2/STIM1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
LigandPNGBDBM50575334(CHEMBL4863881)copy SMILES
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Orai1/STIM1 (unknown origin) expressed in HEK293 cells assessed as reduction in Ca2+-release activated Ca2+ entry current by manual pat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Temple University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50326073((E)-4-(3-(4-Bromo-3-nitrophenyl)-2-(2,4-dichlorobe...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z44N8PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Temple University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50326066((E)-4-(2-(4-Fluorobenzylthio)-3-(4-fluoro-3-nitrop...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z44N8PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Temple University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50326077((E)-4-(2-(Benzylthio)-3-(4-fluoro-3-nitrophenyl)ac...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z44N8PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Temple University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50326065((E)-4-(2-(4-Fluorobenzylthio)-3-(4-chloro-3-nitrop...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z44N8PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Temple University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50326074((E)-4-(3-(4-Fluoro-3-nitrophenyl)-2-(4-methylbenzy...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z44N8PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Temple University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50326089((E)-4-(2-(4-Bromobenzylthio)-3-(4-fluoro-3-nitroph...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z44N8PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Temple University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50326071((E)-4-(3-(4-Chloro-3-nitrophenyl)-2-(2,4-dichlorob...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z44N8PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Temple University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50326072((E)-4-(3-(4-Fluoro-3-nitrophenyl)-2-(2,4-dichlorob...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z44N8PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Temple University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50326064((E)-4-(2-(4-Chlorobenzylthio)-3-(4-bromo-3-nitroph...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z44N8PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Temple University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50326062((E)-4-(2-(4-Chlorobenzylthio)-3-(4-fluoro-3-nitrop...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z44N8PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Temple University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50326068((E)-3-(4-Fluoro-3-nitrophenyl)-2-(4-fluorobenzylth...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z44N8PubMed
LigandPNGBDBM50575335(CHEMBL4570175)copy SMILES
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human STIM1/Orai3 expressed in HEK293 cells assessed as reduction in Orai3 current by electrophysiological methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
LigandPNGBDBM50575335(CHEMBL4570175)copy SMILES
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human STIM1/Orai1 expressed in HEK293 cells assessed as reduction in Orai1 current by electrophysiological methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Temple University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50326060((E)-4-(2-(4-Bromobenzylthio)-3-(4-bromo-3-nitrophe...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z44N8PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Temple University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50326070((E)-4-(2-(2-Chlorobenzylthio)-3-(4-fluoro-3-nitrop...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z44N8PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Temple University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50326059((E)-4-(2-(4-Bromobenzylthio)-3-(4-chloro-3-nitroph...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z44N8PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Temple University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50326063((E)-4-(2-(4-Chlorobenzylthio)-3-(4-chloro-3-nitrop...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z44N8PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Temple University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50326069((E)-4-(3-(4-Chloro-3-nitrophenyl)-2-(2-fluorobenzy...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z44N8PubMed
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