Compile Data Set for Download or QSAR
Found 63 with Last Name = 'pongrac' and Initial = 'r'
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50123474(1-[9-(3-Chloro-4-methoxy-benzylamino)-3-ethyl-3H-2...)copy SMILEScopy InChI
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of Phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125S1GPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50141580(4-(3-Chloro-4-methoxy-benzylamino)-8-ethyl-3-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G1607QPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50123477(CHEMBL344018 | N*9*-(3-Chloro-4-methoxy-benzyl)-3-...)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Inhibition of Phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125S1GPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50023921(CHEMBL2112876)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:In vitro inhibitory concentration against human platelet Phosphodiesterase 5 was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862FP8PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50123473(1-[9-(3-Chloro-4-methoxy-benzylamino)-3-ethyl-3H-2...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Inhibition of Phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125S1GPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104208(8-[5-((R)-3-Dimethylamino-pyrrolidine-1-sulfonyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 0.310nMAssay Description:Inhibition of PDE5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1BM5PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50141584(4-(3-Chloro-4-methoxy-benzylamino)-8-ethyl-quinoli...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G1607QPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50141588(4-(3-Chloro-4-methoxy-benzylamino)-3-hydroxymethyl...)copy SMILEScopy InChI
Affinity DataIC50: 0.480nMAssay Description:Inhibition of phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G1607QPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50086873(3-[1-(4-Fluoro-benzyl)-8-oxo-7,8-dihydro-1H-imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 0.480nMAssay Description:Inhibition of phosphodiesterase type 5 (PDE5) of human plateletsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125RW8PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50086873(3-[1-(4-Fluoro-benzyl)-8-oxo-7,8-dihydro-1H-imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 0.480nMAssay Description:In vitro inhibitory concentration against human platelet Phosphodiesterase 5 was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862FP8PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50023922(CHEMBL2112881)copy SMILEScopy InChI
Affinity DataIC50: 0.520nMAssay Description:In vitro inhibitory concentration against human platelet Phosphodiesterase 5 was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862FP8PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50141586(4-(3-Chloro-4-methoxy-benzylamino)-6-cyano-8-ethyl...)copy SMILEScopy InChI
Affinity DataIC50: 0.550nMAssay Description:Inhibition of phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G1607QPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50089814(4-(3-Chloro-4-methoxy-benzylamino)-1-(4-hydroxy-pi...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of PDE5 of human plateletsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154G8JPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50089814(4-(3-Chloro-4-methoxy-benzylamino)-1-(4-hydroxy-pi...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of Phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125S1GPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50141583(4-(3-Chloro-4-methoxy-benzylamino)-6-cyano-8-ethyl...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G1607QPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50095727(6-[5-(4-Ethyl-piperazine-1-sulfonyl)-2-propoxy-phe...)copy SMILEScopy InChI
Affinity DataIC50: 0.620nMAssay Description:In vitro inhibitory concentration against human platelet Phosphodiesterase 5 was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862FP8PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50123475(1-[9-(3-Chloro-4-methoxy-benzylamino)-3-ethyl-3H-2...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of Phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125S1GPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM14776(2-{2-ethoxy-5-[(4-ethylpiperazine-1-)sulfonyl]phen...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of Phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50098220(4-(3-Chloro-4-methoxy-benzylamino)-1-ethyl-1H-pyra...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Inhibition of Phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125S1GPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50098220(4-(3-Chloro-4-methoxy-benzylamino)-1-ethyl-1H-pyra...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Inhibition of PDE5 of human plateletsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154G8JPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104206(5-(3-Chloro-4-methoxy-benzylamino)-8-[5-((R)-3-dim...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of PDE5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1BM5PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50098226(4-(1-Cyclohexyl-ethylamino)-1-ethyl-1H-pyrazolo[3,...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of PDE5 of human plateletsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154G8JPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50095728(6-[5-(4-Ethyl-piperazine-1-sulfonyl)-2-propoxy-phe...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:In vitro inhibitory concentration against human platelet Phosphodiesterase 5 was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862FP8PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50023919(CHEMBL2112009)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:In vitro inhibitory concentration against human platelet Phosphodiesterase 5 was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862FP8PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50095719(1-Benzyl-6-[5-(4-ethyl-piperazine-1-sulfonyl)-2-pr...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:In vitro inhibitory concentration against human platelet Phosphodiesterase 5 was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862FP8PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM14777((2R,8R)-2-(2H-1,3-benzodioxol-5-yl)-6-methyl-3,6,1...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of Phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50141587(4-(3-Chloro-4-methoxy-benzylamino)-6-cyano-quinoli...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G1607QPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50098225(4-(3-Chloro-4-methoxy-benzylamino)-1-ethyl-1H-pyra...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of PDE5 of human plateletsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154G8JPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50141582(4-(3-Chloro-4-methoxy-benzylamino)-quinoline-6-car...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G1607QPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50095721(6-[5-(4-Ethyl-piperazine-1-sulfonyl)-2-propoxy-phe...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:In vitro inhibitory concentration against human platelet Phosphodiesterase 5 was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862FP8PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of Phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50095726(1-(2-Chloro-benzyl)-6-[5-(4-ethyl-piperazine-1-sul...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:In vitro inhibitory concentration against human platelet Phosphodiesterase 5 was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862FP8PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of PDE5 from human plateletsMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of PDE5 of human plateletsMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:In vitro inhibitory concentration against human platelet Phosphodiesterase 5 was determinedMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50098219(4-(3-Chloro-4-methoxy-benzylamino)-1-ethyl-1H-pyra...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of PDE5 of human plateletsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154G8JPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of phosphodiesterase type 5 (PDE5) of human plateletsMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104204(8-[5-((R)-3-Dimethylamino-pyrrolidine-1-sulfonyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of PDE5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1BM5PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50095720(6-[5-(4-Ethyl-piperazine-1-sulfonyl)-2-propoxy-phe...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:In vitro inhibitory concentration against human platelet Phosphodiesterase 5 was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862FP8PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50098222(4-(3-Chloro-4-methoxy-benzylamino)-1-ethyl-1H-pyra...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of PDE5 of human plateletsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154G8JPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104207(8-[5-((R)-3-Dimethylamino-pyrrolidine-1-sulfonyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Inhibition of PDE5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1BM5PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50095723(3-[1-(4-Fluoro-benzyl)-8-oxo-7,8-dihydro-1H-imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:In vitro inhibitory concentration against human platelet Phosphodiesterase 5 was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862FP8PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50095724(1-(4-Fluoro-benzyl)-6-[5-(4-methyl-piperazine-1-su...)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:In vitro inhibitory concentration against human platelet Phosphodiesterase 5 was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862FP8PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50141579(4-(3-Chloro-4-methoxy-benzylamino)-6-cyano-quinoli...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G1607QPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50086872(1-Benzyl-6-[5-(4-methyl-piperazine-1-sulfonyl)-2-p...)copy SMILEScopy InChI
Affinity DataIC50: 5.30nMAssay Description:In vitro inhibitory concentration against human platelet Phosphodiesterase 5 was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862FP8PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50086872(1-Benzyl-6-[5-(4-methyl-piperazine-1-sulfonyl)-2-p...)copy SMILEScopy InChI
Affinity DataIC50: 5.30nMAssay Description:Inhibition of phosphodiesterase type 5 (PDE5) of human plateletsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125RW8PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50086875(6-[5-(4-Methyl-piperazine-1-sulfonyl)-2-propoxy-ph...)copy SMILEScopy InChI
Affinity DataIC50: 5.30nMAssay Description:Inhibition of phosphodiesterase type 5 (PDE5) of human plateletsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125RW8PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104205(5-Chloro-8-[5-((R)-3-dimethylamino-pyrrolidine-1-s...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of PDE5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1BM5PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50023920(CHEMBL2112879)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:In vitro inhibitory concentration against human platelet Phosphodiesterase 5 was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862FP8PubMed
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