Compile Data Set for Download or QSAR
Found 78 with Last Name = 'prime' and Initial = 'r'
TargetMetabotropic glutamate receptor 1(RAT)
Medical Research Council Technology

Curated by ChEMBL
LigandPNGBDBM50278288(2-(2-(4-(2,3-dihydro-1H-inden-2-ylamino)pyrido[3,4...)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057FSPPubMed
TargetMetabotropic glutamate receptor 1(RAT)
Medical Research Council Technology

Curated by ChEMBL
LigandPNGBDBM50278286(CHEMBL511266 | N4-(2,3-dihydro-1H-inden-2-yl)-N6-(...)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057FSPPubMed
TargetMetabotropic glutamate receptor 1(RAT)
Medical Research Council Technology

Curated by ChEMBL
LigandPNGBDBM50278407(CHEMBL470396 | N-cycloheptyl-6-(2-morpholinoethoxy...)copy SMILEScopy InChI
Affinity DataKi:  6nMAssay Description:Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057FSPPubMed
TargetMetabotropic glutamate receptor 1(RAT)
Medical Research Council Technology

Curated by ChEMBL
LigandPNGBDBM50278361(CHEMBL471435 | N4-cyclohexyl-N6-(2-morpholinoethyl...)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057FSPPubMed
TargetMetabotropic glutamate receptor 1(RAT)
Medical Research Council Technology

Curated by ChEMBL
LigandPNGBDBM50278289(CHEMBL469383 | N4-cyclohexyl-N6-(2-methoxyethyl)py...)copy SMILEScopy InChI
Affinity DataKi:  11nMAssay Description:Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057FSPPubMed
TargetMetabotropic glutamate receptor 1(RAT)
Medical Research Council Technology

Curated by ChEMBL
LigandPNGBDBM50278112(CHEMBL472490 | N4-(2,3-dihydro-1H-inden-2-yl)-N6-m...)copy SMILEScopy InChI
Affinity DataKi:  14nMAssay Description:Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057FSPPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM185975(US9163008, 64 | US9656968, Compound 64)copy SMILEScopy InChI
Affinity DataKi:  16nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6VJMPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50393023(CHEMBL2152688)copy SMILEScopy InChI
Affinity DataKi:  19nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6VJMPubMed
TargetMetabotropic glutamate receptor 1(RAT)
Medical Research Council Technology

Curated by ChEMBL
LigandPNGBDBM50278358(1-(2-(4-(cyclohexylamino)pyrido[3,4-d]pyrimidin-6-...)copy SMILEScopy InChI
Affinity DataKi:  20nMAssay Description:Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057FSPPubMed
TargetMetabotropic glutamate receptor 1(RAT)
Medical Research Council Technology

Curated by ChEMBL
LigandPNGBDBM50278232(2-(4-(2,3-dihydro-1H-inden-2-ylamino)pyrido[3,4-d]...)copy SMILEScopy InChI
Affinity DataKi:  21nMAssay Description:Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057FSPPubMed
TargetMetabotropic glutamate receptor 1(RAT)
Medical Research Council Technology

Curated by ChEMBL
LigandPNGBDBM50278114(CHEMBL513012 | N-cyclohexylquinazolin-4-amine)copy SMILEScopy InChI
Affinity DataKi:  27nMAssay Description:Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057FSPPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50497932(CHEMBL3341989)copy SMILEScopy InChI
Affinity DataKi:  27nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by electrophysiology methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6VJMPubMed
TargetMetabotropic glutamate receptor 1(RAT)
Medical Research Council Technology

Curated by ChEMBL
LigandPNGBDBM50278231(CHEMBL513018 | N4,N6-bis(2,3-dihydro-1H-inden-2-yl...)copy SMILEScopy InChI
Affinity DataKi:  31nMAssay Description:Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057FSPPubMed
TargetMetabotropic glutamate receptor 1(RAT)
Medical Research Council Technology

Curated by ChEMBL
LigandPNGBDBM50278357(3-(4-(cyclohexylamino)pyrido[3,4-d]pyrimidin-6-ylo...)copy SMILEScopy InChI
Affinity DataKi:  33nMAssay Description:Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057FSPPubMed
TargetMetabotropic glutamate receptor 1(RAT)
Medical Research Council Technology

Curated by ChEMBL
LigandPNGBDBM50278153(CHEMBL471242 | N-(2,3-dihydro-1H-inden-2-yl)quinaz...)copy SMILEScopy InChI
Affinity DataKi:  34nMAssay Description:Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057FSPPubMed
TargetMetabotropic glutamate receptor 1(RAT)
Medical Research Council Technology

Curated by ChEMBL
LigandPNGBDBM50278362(CHEMBL512523 | N-cyclohexyl-6-(2-morpholinoethoxy)...)copy SMILEScopy InChI
Affinity DataKi:  42nMAssay Description:Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057FSPPubMed
TargetMetabotropic glutamate receptor 1(RAT)
Medical Research Council Technology

Curated by ChEMBL
LigandPNGBDBM50278111(CHEMBL472489 | N4-(2,3-dihydro-1H-inden-2-yl)-N4,N...)copy SMILEScopy InChI
Affinity DataKi:  54nMAssay Description:Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057FSPPubMed
TargetMetabotropic glutamate receptor 1(RAT)
Medical Research Council Technology

Curated by ChEMBL
LigandPNGBDBM50278291(CHEMBL471666 | N-cyclohexyl-6-(2-methoxyethoxy)pyr...)copy SMILEScopy InChI
Affinity DataKi:  101nMAssay Description:Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057FSPPubMed
TargetMetabotropic glutamate receptor 1(RAT)
Medical Research Council Technology

Curated by ChEMBL
LigandPNGBDBM50278287(CHEMBL469381 | N4-(2,3-dihydro-1H-inden-2-yl)-N6-(...)copy SMILEScopy InChI
Affinity DataKi:  102nMAssay Description:Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057FSPPubMed
TargetMetabotropic glutamate receptor 1(RAT)
Medical Research Council Technology

Curated by ChEMBL
LigandPNGBDBM50278113(CHEMBL513761 | N-(2,3-dihydro-1H-inden-2-yl)-6-met...)copy SMILEScopy InChI
Affinity DataKi:  115nMAssay Description:Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057FSPPubMed
TargetMetabotropic glutamate receptor 1(RAT)
Medical Research Council Technology

Curated by ChEMBL
LigandPNGBDBM50278229(2-(6-(2,3-dihydro-1H-inden-2-ylamino)pyrido[3,4-d]...)copy SMILEScopy InChI
Affinity DataKi:  125nMAssay Description:Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057FSPPubMed
TargetMetabotropic glutamate receptor 1(RAT)
Medical Research Council Technology

Curated by ChEMBL
LigandPNGBDBM50278228(CHEMBL447113 | N6-(2,3-dihydro-1H-inden-2-yl)-N4-m...)copy SMILEScopy InChI
Affinity DataKi:  160nMAssay Description:Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057FSPPubMed
TargetMetabotropic glutamate receptor 1(RAT)
Medical Research Council Technology

Curated by ChEMBL
LigandPNGBDBM50278290(2-(4-(cyclohexylamino)pyrido[3,4-d]pyrimidin-6-ylo...)copy SMILEScopy InChI
Affinity DataKi:  177nMAssay Description:Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057FSPPubMed
TargetMetabotropic glutamate receptor 1(RAT)
Medical Research Council Technology

Curated by ChEMBL
LigandPNGBDBM50278853(CHEMBL496897 | N4-(2,3-dihydro-1H-inden-2-yl)-N6,N...)copy SMILEScopy InChI
Affinity DataKi:  185nMAssay Description:Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057FSPPubMed
TargetMetabotropic glutamate receptor 1(RAT)
Medical Research Council Technology

Curated by ChEMBL
LigandPNGBDBM50278850(CHEMBL497918 | N4-cyclohexyl-N6,N6-dimethylpyrido[...)copy SMILEScopy InChI
Affinity DataKi:  199nMAssay Description:Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057FSPPubMed
TargetMetabotropic glutamate receptor 1(RAT)
Medical Research Council Technology

Curated by ChEMBL
LigandPNGBDBM50278360(CHEMBL471434 | N6-(3-aminopropyl)-N4-cyclohexylpyr...)copy SMILEScopy InChI
Affinity DataKi:  200nMAssay Description:Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057FSPPubMed
TargetMetabotropic glutamate receptor 1(RAT)
Medical Research Council Technology

Curated by ChEMBL
LigandPNGBDBM50278110(CHEMBL511838 | N4-(2,3-dihydro-1H-inden-2-yl)-N4,N...)copy SMILEScopy InChI
Affinity DataKi:  300nMAssay Description:Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057FSPPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM190561(US9181185, 19 | US9624194, Compound 19)copy SMILEScopy InChI
Affinity DataKi:  347nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6VJMPubMed
TargetMetabotropic glutamate receptor 1(RAT)
Medical Research Council Technology

Curated by ChEMBL
LigandPNGBDBM50278116(4-(cyclohexyloxy)quinazoline | CHEMBL471866)copy SMILEScopy InChI
Affinity DataKi:  694nMAssay Description:Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057FSPPubMed
TargetMetabotropic glutamate receptor 1(RAT)
Medical Research Council Technology

Curated by ChEMBL
LigandPNGBDBM50278852(CHEMBL525546 | N6,N6-dimethyl-N4-(pentan-2-yl)pyri...)copy SMILEScopy InChI
Affinity DataKi:  858nMAssay Description:Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057FSPPubMed
TargetMetabotropic glutamate receptor 1(RAT)
Medical Research Council Technology

Curated by ChEMBL
LigandPNGBDBM50278851((S)-N6,N6-dimethyl-N4-(1-phenylethyl)pyrido[3,4-d]...)copy SMILEScopy InChI
Affinity DataKi:  1.40E+3nMAssay Description:Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057FSPPubMed
TargetMetabotropic glutamate receptor 1(RAT)
Medical Research Council Technology

Curated by ChEMBL
LigandPNGBDBM50278227(CHEMBL470205 | N-(2,3-dihydro-1H-inden-2-yl)isoqui...)copy SMILEScopy InChI
Affinity DataKi:  1.65E+3nMAssay Description:Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057FSPPubMed
TargetMetabotropic glutamate receptor 1(RAT)
Medical Research Council Technology

Curated by ChEMBL
LigandPNGBDBM50278359(CHEMBL509066 | N6-(2-aminoethyl)-N4-cyclohexylpyri...)copy SMILEScopy InChI
Affinity DataKi:  2.20E+3nMAssay Description:Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057FSPPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM236497(US9388137, 1)copy SMILEScopy InChI
Affinity DataKi:  6.03E+3nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by electrophysiology methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6VJMPubMed
TargetMetabotropic glutamate receptor 1(RAT)
Medical Research Council Technology

Curated by ChEMBL
LigandPNGBDBM50278230(2,2'-(pyrido[3,4-d]pyrimidine-4,6-diylbis(azanediy...)copy SMILEScopy InChI
Affinity DataKi:  6.15E+3nMAssay Description:Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057FSPPubMed
TargetMetabotropic glutamate receptor 1(RAT)
Medical Research Council Technology

Curated by ChEMBL
LigandPNGBDBM50278115(CHEMBL449616 | N-cyclohexylquinolin-4-amine)copy SMILEScopy InChI
Affinity DataKi:  6.16E+3nMAssay Description:Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057FSPPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50169425(CHEMBL3341983 | US9481677, 44)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of Nav1.7 (unknown origin) by PatchXpress methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6VJMPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM275868(US10071957, Example 87)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Inhibition of Nav1.7 (unknown origin) by PatchXpress methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6VJMPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM258159(US9493448, 61 | US9845313, Example 61)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by PatchXpress methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6VJMPubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Medical Research Council Technology

Curated by ChEMBL
LigandPNGBDBM50278288(2-(2-(4-(2,3-dihydro-1H-inden-2-ylamino)pyrido[3,4...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Antagonist activity at mGluR1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057FSPPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50024245(CHEMBL3325524)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Inhibition of Nav1.7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6VJMPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM145227(US8952169, 6 | US9771376, Example 6)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMAssay Description:Inhibition of Nav1.7 (unknown origin) by PatchXpress methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6VJMPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50497931(CHEMBL3341986)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by PatchXpress methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6VJMPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM154456(US9012443, 521)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of Nav1.7 (unknown origin) expressed in HEK293 cells by PatchXpress methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6VJMPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM162249(US9051311, 6)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of Nav1.7 (unknown origin) expressed in HEK293 cells by PatchXpress methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6VJMPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50497937(CHEMBL3341976)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of human Nav1.7 expressed in HEK cells by whole-cell patch-clamp techniqueMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6VJMPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM170190(US9079902, 21)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of Nav1.7 (unknown origin) expressed in HEK293 cells by PatchXpress methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6VJMPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM231255(US9346798, 2)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibition of Nav1.7 (unknown origin) expressed in HEK293 cells by PatchXpress methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6VJMPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50497932(CHEMBL3341989)copy SMILEScopy InChI
Affinity DataIC50: 67nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by FLIPR methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6VJMPubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50497939(CHEMBL3341974)copy SMILEScopy InChI
Affinity DataIC50: 127nMAssay Description:Inhibition of human Nav1 .8 expressed in HEK cells by PatchXpress electrophysiological assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6VJMPubMed
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