Compile Data Set for Download or QSAR
Found 170 with Last Name = 'radinsky' and Initial = 'r'
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Amgen

LigandPNGBDBM24773(AMG 706 | AMG-706 | Motesanib | N-(3,3-dimethyl-1,...)copy SMILEScopy InChI
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057D73PubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50340122(CHEMBL1760036 | N4-(naphthalen-2-yl)-N2-(3,4,5-tri...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8M0DPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50340126(CHEMBL1738698 | N2-(3-methoxy-4-morpholinophenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50340121(CHEMBL1760035 | N4-(quinolin-3-yl)-N2-(3,4,5-trime...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8M0DPubMed
TargetInsulin receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50340121(CHEMBL1760035 | N4-(quinolin-3-yl)-N2-(3,4,5-trime...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of INSRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8M0DPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM24773(AMG 706 | AMG-706 | Motesanib | N-(3,3-dimethyl-1,...)copy SMILEScopy InChI
Affinity DataIC50: 3nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50340128(CHEMBL1760041 | N4-(quinolin-6-yl)-N2-(3,4,5-trime...)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8M0DPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50340144(CHEMBL1760058 | N2-(3-methoxy-4-(3-(piperidin-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8M0DPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50340127(CHEMBL1760040 | N4-(isoquinolin-3-yl)-N2-(3,4,5-tr...)copy SMILEScopy InChI
Affinity DataIC50: 5.20nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8M0DPubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Amgen

LigandPNGBDBM24773(AMG 706 | AMG-706 | Motesanib | N-(3,3-dimethyl-1,...)copy SMILEScopy InChI
Affinity DataIC50: 6nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057D73PubMed
LigandPNGBDBM24773(AMG 706 | AMG-706 | Motesanib | N-(3,3-dimethyl-1,...)copy SMILEScopy InChI
Affinity DataIC50: 6nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057D73PubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Amgen

LigandPNGBDBM24773(AMG 706 | AMG-706 | Motesanib | N-(3,3-dimethyl-1,...)copy SMILEScopy InChI
Affinity DataIC50: 8nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057D73PubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50340126(CHEMBL1738698 | N2-(3-methoxy-4-morpholinophenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 8.40nMAssay Description:Inhibition of IGF1-induced human IGF1R auto phosphorylation expressed in mouse NIH-3T3 cells preincubated with compound for 1 hrMore data for this Ligand-Target Pair
TargetAurora kinase B(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50326206(CHEMBL1243200 | N-(4-(3-(2-(Methylamino)pyrimidin-...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of Aurora B by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C829H0PubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50340120(CHEMBL1760034 | N2-(naphthalen-2-yl)-N4-(3,4,5-tri...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8M0DPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50340127(CHEMBL1760040 | N4-(isoquinolin-3-yl)-N2-(3,4,5-tr...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of IGF1-induced human IGF1R auto phosphorylation expressed in mouse NIH-3T3 cells preincubated with compound for 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8M0DPubMed
TargetAurora kinase B(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50326208(4-(4-Fluorophenyl)-N-(4-(3-(2-(methylamino)pyrimid...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of Aurora B by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C829H0PubMed
TargetAurora kinase B(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50326204(CHEMBL1243137 | N-(3-Methyl-4-(3-(2-(methylamino)p...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of Aurora B by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C829H0PubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50340135(CHEMBL1760049 | N2-(3,4-dimethoxyphenyl)-N4-(quino...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8M0DPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50340121(CHEMBL1760035 | N4-(quinolin-3-yl)-N2-(3,4,5-trime...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of IGF1-induced human IGF1R auto phosphorylation expressed in mouse NIH-3T3 cells preincubated with compound for 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8M0DPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50340143(CHEMBL1760057 | N2-(4-(3-(piperidin-1-yl)propoxy)p...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8M0DPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50340136(CHEMBL1760050 | N2-(3,5-dimethoxyphenyl)-N4-(quino...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8M0DPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50340142(CHEMBL1760056 | N2-(4-morpholinophenyl)-N4-(quinol...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8M0DPubMed
TargetAurora kinase B(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50326207(CHEMBL1243294 | N-(4-(3-(2-(Methylamino)pyrimidin-...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of Aurora B by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C829H0PubMed
TargetInsulin receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50340143(CHEMBL1760057 | N2-(4-(3-(piperidin-1-yl)propoxy)p...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of INSRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8M0DPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50340118(CHEMBL1760048 | N4-(3-(trifluoromethoxy)phenyl)-N2...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8M0DPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50340131(CHEMBL1760044 | N4-(1H-indazol-5-yl)-N2-(3,4,5-tri...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8M0DPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50340144(CHEMBL1760058 | N2-(3-methoxy-4-(3-(piperidin-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of IGF1-induced human IGF1R auto phosphorylation expressed in mouse NIH-3T3 cells preincubated with compound for 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8M0DPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50340141(CHEMBL1760055 | N2-(3-chloro-4-methoxyphenyl)-N4-(...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8M0DPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50340128(CHEMBL1760041 | N4-(quinolin-6-yl)-N2-(3,4,5-trime...)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Inhibition of IGF1-induced human IGF1R auto phosphorylation expressed in mouse NIH-3T3 cells preincubated with compound for 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8M0DPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50340138(CHEMBL1760052 | N2-(3-methoxyphenyl)-N4-(quinolin-...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8M0DPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50340119(CHEMBL1760033 | N2-(quinolin-3-yl)-N4-(3,4,5-trime...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8M0DPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50340140(CHEMBL1760054 | N2-(3-chlorophenyl)-N4-(quinolin-3...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8M0DPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50340123(CHEMBL1760037 | N4-(2-methylquinolin-3-yl)-N2-(3,4...)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8M0DPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50131840(CHEMBL3633142)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Binding affinity against delta opioid receptor in mouse hot plate testMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1ZPNPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50340137(CHEMBL1760051 | N2-(4-methoxyphenyl)-N4-(quinolin-...)copy SMILEScopy InChI
Affinity DataIC50: 55nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8M0DPubMed
TargetAurora kinase B(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50326202(CHEMBL1243042 | N-(3-Methyl-4-(3-(2-(methylamino)p...)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Inhibition of Aurora B by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C829H0PubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50340129(CHEMBL1760042 | N4-(quinoxalin-6-yl)-N2-(3,4,5-tri...)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8M0DPubMed
LigandPNGBDBM24773(AMG 706 | AMG-706 | Motesanib | N-(3,3-dimethyl-1,...)copy SMILEScopy InChI
Affinity DataIC50: 59nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057D73PubMed
TargetAurora kinase B(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50326198(CHEMBL1242977 | N-(3-Methyl-4-(3-(2-(methylamino)p...)copy SMILEScopy InChI
Affinity DataIC50: 66nMAssay Description:Inhibition of Aurora B by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C829H0PubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50340143(CHEMBL1760057 | N2-(4-(3-(piperidin-1-yl)propoxy)p...)copy SMILEScopy InChI
Affinity DataIC50: 81nMAssay Description:Inhibition of IGF1-induced human IGF1R auto phosphorylation expressed in mouse NIH-3T3 cells preincubated with compound for 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8M0DPubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Amgen

LigandPNGBDBM24773(AMG 706 | AMG-706 | Motesanib | N-(3,3-dimethyl-1,...)copy SMILEScopy InChI
Affinity DataIC50: 84nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057D73PubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50340122(CHEMBL1760036 | N4-(naphthalen-2-yl)-N2-(3,4,5-tri...)copy SMILEScopy InChI
Affinity DataIC50: 88nMAssay Description:Inhibition of IGF1-induced human IGF1R auto phosphorylation expressed in mouse NIH-3T3 cells preincubated with compound for 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8M0DPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM50340121(CHEMBL1760035 | N4-(quinolin-3-yl)-N2-(3,4,5-trime...)copy SMILEScopy InChI
Affinity DataIC50: 94nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8M0DPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50340130(CHEMBL1760043 | N4-(1H-indazol-6-yl)-N2-(3,4,5-tri...)copy SMILEScopy InChI
Affinity DataIC50: 103nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8M0DPubMed
TargetAurora kinase B(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50326205(CHEMBL1243167 | N-(2-Methyl-4-(3-(2-(methylamino)p...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of Aurora B by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C829H0PubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50340133(CHEMBL1760046 | N4-(3,3-dimethylindolin-6-yl)-N2-(...)copy SMILEScopy InChI
Affinity DataIC50: 123nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8M0DPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50340119(CHEMBL1760033 | N2-(quinolin-3-yl)-N4-(3,4,5-trime...)copy SMILEScopy InChI
Affinity DataIC50: 175nMAssay Description:Inhibition of IGF1-induced human IGF1R auto phosphorylation expressed in mouse NIH-3T3 cells preincubated with compound for 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8M0DPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50340142(CHEMBL1760056 | N2-(4-morpholinophenyl)-N4-(quinol...)copy SMILEScopy InChI
Affinity DataIC50: 177nMAssay Description:Inhibition of IGF1-induced human IGF1R auto phosphorylation expressed in mouse NIH-3T3 cells preincubated with compound for 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8M0DPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50340139(CHEMBL1760053 | N4-(quinolin-3-yl)-N2-(3-(trifluor...)copy SMILEScopy InChI
Affinity DataIC50: 198nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8M0DPubMed
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