TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Pfizer Global Research & Development
Curated by ChEMBL
Pfizer Global Research & Development
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Binding affinity to human recombinant GnRH receptorMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Pfizer Global Research & Development
Curated by ChEMBL
Pfizer Global Research & Development
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Binding affinity to rat pituitary GnRH receptorMore data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:Inhibition of human carbonic anhydrase 2 by CO2 hydrase stopped flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Inhibition of human carbonic anhydrase 2 by CO2 hydrase stopped flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Inhibition of human carbonic anhydrase 2 by CO2 hydrase stopped flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 43nMAssay Description:Inhibition of human carbonic anhydrase 4 by CO2 hydrase stopped flow assayMore data for this Ligand-Target Pair
In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q2X92C80PubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q2X92C80PubMedDrugBank
MMDB
PDB
![3D 3D](/images/Docked_3d.png)
Affinity DataKi: 46nMAssay Description:Inhibition of human carbonic anhydrase 4 by CO2 hydrase stopped flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 63nMAssay Description:Inhibition of human carbonic anhydrase 2 by CO2 hydrase stopped flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 71nMAssay Description:Inhibition of human carbonic anhydrase 2 by CO2 hydrase stopped flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 76nMAssay Description:Inhibition of human carbonic anhydrase 2 by CO2 hydrase stopped flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 181nMAssay Description:Inhibition of human carbonic anhydrase 4 by CO2 hydrase stopped flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 339nMAssay Description:Inhibition of human carbonic anhydrase 4 by CO2 hydrase stopped flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 410nMAssay Description:Inhibition of human carbonic anhydrase 1 by CO2 hydrase stopped flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 470nMAssay Description:Inhibition of human carbonic anhydrase 1 by CO2 hydrase stopped flow assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer Global Research & Development
Curated by ChEMBL
Pfizer Global Research & Development
Curated by ChEMBL
Affinity DataKi: 583nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Homo sapiens (Human))
Pfizer Global Research & Development
Curated by ChEMBL
Pfizer Global Research & Development
Curated by ChEMBL
Affinity DataKi: 628nMAssay Description:Binding affinity to human A3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 705nMAssay Description:Inhibition of human carbonic anhydrase 1 by CO2 hydrase stopped flow assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer Global Research & Development
Curated by ChEMBL
Pfizer Global Research & Development
Curated by ChEMBL
Affinity DataKi: 964nMAssay Description:Binding affinity to human 5HT2C receptorMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer Global R&D
Curated by ChEMBL
Pfizer Global R&D
Curated by ChEMBL
Affinity DataKi: 1.02E+3nMAssay Description:Binding affinity to human ERGMore data for this Ligand-Target Pair
TargetPlatelet-activating factor receptor(Homo sapiens (Human))
Pfizer Global Research & Development
Curated by ChEMBL
Pfizer Global Research & Development
Curated by ChEMBL
Affinity DataKi: 1.06E+3nMAssay Description:Binding affinity to PAFMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Pfizer Global Research & Development
Curated by ChEMBL
Pfizer Global Research & Development
Curated by ChEMBL
Affinity DataKi: 1.18E+3nMAssay Description:Binding affinity to human D3 receptorMore data for this Ligand-Target Pair
TargetHistamine H2 receptor(Homo sapiens (Human))
Pfizer Global Research & Development
Curated by ChEMBL
Pfizer Global Research & Development
Curated by ChEMBL
Affinity DataKi: 1.22E+3nMAssay Description:Binding affinity to H2 receptorMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Pfizer Global Research & Development
Curated by ChEMBL
Pfizer Global Research & Development
Curated by ChEMBL
Affinity DataKi: 1.25E+3nMAssay Description:Binding affinity to human NK1 receptorMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Pfizer Global Research & Development
Curated by ChEMBL
Pfizer Global Research & Development
Curated by ChEMBL
Affinity DataKi: 1.40E+3nMAssay Description:Binding affinity to human mu opiate receptorMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer Global Research & Development
Curated by ChEMBL
Pfizer Global Research & Development
Curated by ChEMBL
Affinity DataKi: 1.43E+3nMAssay Description:Binding affinity to human 5HT transporterMore data for this Ligand-Target Pair
Affinity DataKi: 1.52E+3nMAssay Description:Inhibition of human carbonic anhydrase 1 by CO2 hydrase stopped flow assayMore data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Pfizer Global Research & Development
Curated by ChEMBL
Pfizer Global Research & Development
Curated by ChEMBL
Affinity DataKi: 1.62E+3nMAssay Description:Binding affinity to human D1 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Pfizer Global Research & Development
Curated by ChEMBL
Pfizer Global Research & Development
Curated by ChEMBL
Affinity DataKi: 1.75E+3nMAssay Description:Binding affinity to human 5HT7 receptorMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Pfizer Global Research & Development
Curated by ChEMBL
Pfizer Global Research & Development
Curated by ChEMBL
Affinity DataKi: 1.80E+3nMAssay Description:Binding affinity to human DA transporterMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
Pfizer Global Research & Development
Curated by ChEMBL
Pfizer Global Research & Development
Curated by ChEMBL
Affinity DataKi: 1.96E+3nMAssay Description:Binding affinity to kappa opiate receptorMore data for this Ligand-Target Pair
TargetD(4) dopamine receptor(Homo sapiens (Human))
Pfizer Global Research & Development
Curated by ChEMBL
Pfizer Global Research & Development
Curated by ChEMBL
Affinity DataKi: 2.51E+3nMAssay Description:Binding affinity to human D4.4 receptorMore data for this Ligand-Target Pair
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