Compile Data Set for Download or QSAR
Found 133 with Last Name = 'ronn' and Initial = 'r'
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM223288((1S,2S)-2-[(5-{(2-Fluoro-2-methylpropyl)[2-fluoro-...)copy SMILEScopy InChI
Affinity DataIC50: 0.248nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1NPGUS Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM223288((1S,2S)-2-[(5-{(2-Fluoro-2-methylpropyl)[2-fluoro-...)copy SMILEScopy InChI
Affinity DataIC50: 0.248nMpH: 7.5Assay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester. In order to obtain IC50-v...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W66JN5US Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM223287((1S,2S)-2-({5-[(5-Chloro-2,4-difluorophenyl)(2-flu...)copy SMILEScopy InChI
Affinity DataIC50: 0.289nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1NPGUS Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM223287((1S,2S)-2-({5-[(5-Chloro-2,4-difluorophenyl)(2-flu...)copy SMILEScopy InChI
Affinity DataIC50: 0.289nMpH: 7.5Assay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester. In order to obtain IC50-v...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W66JN5US Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM310035((1S,2S)-2-({5-[(5-Chloro-2,4-difluorophenyl)(propy...)copy SMILEScopy InChI
Affinity DataIC50: 0.483nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1NPGUS Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM223289((1S,2S)-2-({5-[(5-Chloro-2,4-difluorophenyl)(propy...)copy SMILEScopy InChI
Affinity DataIC50: 0.483nMpH: 7.5Assay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester. In order to obtain IC50-v...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W66JN5US Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM223290((1S,2S)-2-[(5-{[2-Fluoro-5-(trifluoromethyl)phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 0.658nMpH: 7.5Assay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester. In order to obtain IC50-v...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W66JN5US Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM223290((1S,2S)-2-[(5-{[2-Fluoro-5-(trifluoromethyl)phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 0.658nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1NPGUS Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM223261(2-(5-((Cyclopropylmethyl)(1,2-dihydroacenaphthylen...)copy SMILEScopy InChI
Affinity DataIC50: 9nMpH: 7.8Assay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 is converted to LTC4. Recombinant human LTC4 synthase is expressed in Pic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W66JN5US Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM223261(2-(5-((Cyclopropylmethyl)(1,2-dihydroacenaphthylen...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1NPGUS Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM223281(2-(5-((Cyclopropylmethyl)(naphthalen-1-yl)amino)-4...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1NPGUS Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM223281(2-(5-((Cyclopropylmethyl)(naphthalen-1-yl)amino)-4...)copy SMILEScopy InChI
Affinity DataIC50: 17nMpH: 7.8Assay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 is converted to LTC4. Recombinant human LTC4 synthase is expressed in Pic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W66JN5US Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM223284(2-(5-((Cyclopropylmethyl)(4-methylnaphthalen-1-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 18nMpH: 7.8Assay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 is converted to LTC4. Recombinant human LTC4 synthase is expressed in Pic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W66JN5US Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM223284(2-(5-((Cyclopropylmethyl)(4-methylnaphthalen-1-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1NPGUS Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM223226(2-(5-((4-Chloronaphthalen-1-yl)(cyclopropylmethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 18nMpH: 7.8Assay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 is converted to LTC4. Recombinant human LTC4 synthase is expressed in Pic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W66JN5US Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM223232(2-(5-((Cyclopropylmethyl)(4-fluoronaphthalen-1-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 18nMpH: 7.8Assay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 is converted to LTC4. Recombinant human LTC4 synthase is expressed in Pic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W66JN5US Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM223226(2-(5-((4-Chloronaphthalen-1-yl)(cyclopropylmethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1NPGUS Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM223232(2-(5-((Cyclopropylmethyl)(4-fluoronaphthalen-1-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1NPGUS Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM223259(2-(5-((Cyclopropylmethyl)(4-(trifluoromethyl)napht...)copy SMILEScopy InChI
Affinity DataIC50: 19nMpH: 7.8Assay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 is converted to LTC4. Recombinant human LTC4 synthase is expressed in Pic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W66JN5US Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM223283(2-(5-((Cyclopropylmethyl)(4-fluoronaphthalen-1-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 19nMpH: 7.8Assay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 is converted to LTC4. Recombinant human LTC4 synthase is expressed in Pic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W66JN5US Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM310005(2-(5-((Cyclopropylmethyl)(4-(trifluoromethyl)napht...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1NPGUS Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM223283(2-(5-((Cyclopropylmethyl)(4-fluoronaphthalen-1-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1NPGUS Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM223239(2-(5-((Cyclopropylmethyl)(4-methylbenzyl)amino)-3-...)copy SMILEScopy InChI
Affinity DataIC50: 22nMpH: 7.8Assay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 is converted to LTC4. Recombinant human LTC4 synthase is expressed in Pic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W66JN5US Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM223239(2-(5-((Cyclopropylmethyl)(4-methylbenzyl)amino)-3-...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1NPGUS Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM223234(2-(5-((Cyclopropylmethyl)(naphthalen-1-yl)amino)-3...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1NPGUS Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM223234(2-(5-((Cyclopropylmethyl)(naphthalen-1-yl)amino)-3...)copy SMILEScopy InChI
Affinity DataIC50: 24nMpH: 7.8Assay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 is converted to LTC4. Recombinant human LTC4 synthase is expressed in Pic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W66JN5US Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM223262(2-(5-((Cyclopropylmethyl)(5-(trifluoromethyl)napht...)copy SMILEScopy InChI
Affinity DataIC50: 25nMpH: 7.8Assay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 is converted to LTC4. Recombinant human LTC4 synthase is expressed in Pic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W66JN5US Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM223262(2-(5-((Cyclopropylmethyl)(5-(trifluoromethyl)napht...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1NPGUS Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM223271(2-(4-((Cyclopropylmethyl)(4-fluoronaphthalen-1-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 26nMpH: 7.8Assay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 is converted to LTC4. Recombinant human LTC4 synthase is expressed in Pic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W66JN5US Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM223271(2-(4-((Cyclopropylmethyl)(4-fluoronaphthalen-1-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1NPGUS Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM223237(2-(5-((Cyclopropylmethyl)(naphthalen-2-yl)amino)-3...)copy SMILEScopy InChI
Affinity DataIC50: 28nMpH: 7.8Assay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 is converted to LTC4. Recombinant human LTC4 synthase is expressed in Pic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W66JN5US Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM223237(2-(5-((Cyclopropylmethyl)(naphthalen-2-yl)amino)-3...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1NPGUS Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM223263(2-(5-((Cyclopropylmethyl)(1,2-dihydroacenaphthylen...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1NPGUS Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM223263(2-(5-((Cyclopropylmethyl)(1,2-dihydroacenaphthylen...)copy SMILEScopy InChI
Affinity DataIC50: 31nMpH: 7.8Assay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 is converted to LTC4. Recombinant human LTC4 synthase is expressed in Pic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W66JN5US Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM223227(2-(5-((4-Chlorobenzyl)(cyclopropylmethyl)amino)-3-...)copy SMILEScopy InChI
Affinity DataIC50: 34nMpH: 7.8Assay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 is converted to LTC4. Recombinant human LTC4 synthase is expressed in Pic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W66JN5US Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM223242(2-(5-((Cyclopropylmethyl)(naphthalen-2-ylmethyl)am...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1NPGUS Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM223242(2-(5-((Cyclopropylmethyl)(naphthalen-2-ylmethyl)am...)copy SMILEScopy InChI
Affinity DataIC50: 34nMpH: 7.8Assay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 is converted to LTC4. Recombinant human LTC4 synthase is expressed in Pic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W66JN5US Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM309984(2-(5-((4-Chlorobenzyl)(cyclopropylmethyl)amino)-3-...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1NPGUS Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM223236(2-(5-((Cyclopropylmethyl)(4-methylnaphthalen-1-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1NPGUS Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM223236(2-(5-((Cyclopropylmethyl)(4-methylnaphthalen-1-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 35nMpH: 7.8Assay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 is converted to LTC4. Recombinant human LTC4 synthase is expressed in Pic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W66JN5US Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM223230(2-(5-((4-Chlorophenyl)((1-methylcyclopropyl)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1NPGUS Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM223230(2-(5-((4-Chlorophenyl)((1-methylcyclopropyl)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 38nMpH: 7.8Assay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 is converted to LTC4. Recombinant human LTC4 synthase is expressed in Pic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W66JN5US Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM223243(2-(5-((3-Chlorobenzyl)(cyclopropylmethyl)amino)-3-...)copy SMILEScopy InChI
Affinity DataIC50: 39nMpH: 7.8Assay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 is converted to LTC4. Recombinant human LTC4 synthase is expressed in Pic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W66JN5US Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM223286((2-(1H-Tetrazol-5-yl)cyclopropyl)(5-((cyclopropylm...)copy SMILES
Affinity DataIC50: 39nMpH: 7.8Assay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 is converted to LTC4. Recombinant human LTC4 synthase is expressed in Pic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W66JN5US Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM223243(2-(5-((3-Chlorobenzyl)(cyclopropylmethyl)amino)-3-...)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1NPGUS Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM223286((2-(1H-Tetrazol-5-yl)cyclopropyl)(5-((cyclopropylm...)copy SMILES
Affinity DataIC50: 39nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1NPGUS Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM223273(2-(4-((Cyclopropylmethyl)(naphthalen-1-yl)amino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 46nMpH: 7.8Assay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 is converted to LTC4. Recombinant human LTC4 synthase is expressed in Pic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W66JN5US Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM223273(2-(4-((Cyclopropylmethyl)(naphthalen-1-yl)amino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1NPGUS Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM223231(2-(5-((2,3-Dihydro-1H-inden-5-yl)((1-methylcyclopr...)copy SMILEScopy InChI
Affinity DataIC50: 47nMpH: 7.8Assay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 is converted to LTC4. Recombinant human LTC4 synthase is expressed in Pic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W66JN5US Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM309977(US9657001, 6)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1NPGUS Patent
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