TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute of Bio-Science and Technology
Curated by ChEMBL
Institute of Bio-Science and Technology
Curated by ChEMBL
Affinity DataKi: 340nMAssay Description:Competitive inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate Linewea...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Bio-Science and Technology
Curated by ChEMBL
Institute of Bio-Science and Technology
Curated by ChEMBL
Affinity DataKi: 580nMAssay Description:Noncompetitive inhibition of chymotrypsin-like activity of human 20S proteasome beta 5 subunit assessed as hydrolysis of succinyl-LLVY-AMC fluorogeni...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute of Bio-Science and Technology
Curated by ChEMBL
Institute of Bio-Science and Technology
Curated by ChEMBL
Affinity DataKi: 670nMAssay Description:Competitive inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate Linewea...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Bio-Science and Technology
Curated by ChEMBL
Institute of Bio-Science and Technology
Curated by ChEMBL
Affinity DataKi: 870nMAssay Description:Noncompetitive inhibition of chymotrypsin-like activity of human 20S proteasome beta 5 subunit assessed as hydrolysis of succinyl-LLVY-AMC fluorogeni...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute of Bio-Science and Technology
Curated by ChEMBL
Institute of Bio-Science and Technology
Curated by ChEMBL
Affinity DataKi: 1.02E+3nMAssay Description:Competitive inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate Linewea...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Bio-Science and Technology
Curated by ChEMBL
Institute of Bio-Science and Technology
Curated by ChEMBL
Affinity DataKi: 1.10E+3nMAssay Description:Noncompetitive inhibition of chymotrypsin-like activity of human 20S proteasome beta 5 subunit assessed as hydrolysis of succinyl-LLVY-AMC fluorogeni...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Bio-Science and Technology
Curated by ChEMBL
Institute of Bio-Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-LLVY-MCA as substrate measured for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Bio-Science and Technology
Curated by ChEMBL
Institute of Bio-Science and Technology
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta 5 subunit assessed as hydrolysis of succinyl-LLVY-AMC fluorogenic substrate mea...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute of Bio-Science and Technology
Curated by ChEMBL
Institute of Bio-Science and Technology
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of PGPH activity of human 26S proteasome using Z-LLE-MCA as substrate measured for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute of Bio-Science and Technology
Curated by ChEMBL
Institute of Bio-Science and Technology
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate measured for 1 hr b...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Bio-Science and Technology
Curated by ChEMBL
Institute of Bio-Science and Technology
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-LLVY-MCA as substrate measured for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 2A(Homo sapiens (Human))
Kyoto Prefectural University of Medicine
Curated by ChEMBL
Kyoto Prefectural University of Medicine
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of KDM2A (unknown origin)More data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Nagahama Institute of Bio-Science and Technology
Curated by ChEMBL
Nagahama Institute of Bio-Science and Technology
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of trypsin-like activity of human 20S proteasome using Boc-LRR-MCA as substrate measured for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Nagahama Institute of Bio-Science and Technology
Curated by ChEMBL
Nagahama Institute of Bio-Science and Technology
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of trypsin-like activity of human 20S proteasome beta 2 subunit assessed as hydrolysis of Boc-LRR-AMC fluorogenic substrate measured for 1...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute of Bio-Science and Technology
Curated by ChEMBL
Institute of Bio-Science and Technology
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Inhibition of PGPH activity of human 20S proteasome using Z-LLE-MCA as substrate measured for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Nagahama Institute of Bio-Science and Technology
Curated by ChEMBL
Nagahama Institute of Bio-Science and Technology
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Inhibition of trypsin-like activity of human 20S proteasome beta 2 subunit assessed as hydrolysis of Boc-LRR-AMC fluorogenic substrate measured for 1...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Waseda University
Curated by ChEMBL
Waseda University
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of human LSD1 using H3K4 peptide as substrate by peroxidase-coupled assayMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Nagahama Institute of Bio-Science and Technology
Curated by ChEMBL
Nagahama Institute of Bio-Science and Technology
Curated by ChEMBL
Affinity DataIC50: 340nMAssay Description:Inhibition of trypsin-like activity of human 20S proteasome beta 2 subunit assessed as hydrolysis of Boc-LRR-AMC fluorogenic substrate measured for 1...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute of Bio-Science and Technology
Curated by ChEMBL
Institute of Bio-Science and Technology
Curated by ChEMBL
Affinity DataIC50: 350nMAssay Description:Inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate measured for 1 hr b...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Nagahama Institute of Bio-Science and Technology
Curated by ChEMBL
Nagahama Institute of Bio-Science and Technology
Curated by ChEMBL
Affinity DataIC50: 350nMAssay Description:Inhibition of trypsin-like activity of human 20S proteasome using Boc-LRR-MCA as substrate measured for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Nagahama Institute of Bio-Science and Technology
Curated by ChEMBL
Nagahama Institute of Bio-Science and Technology
Curated by ChEMBL
Affinity DataIC50: 360nMAssay Description:Inhibition of trypsin-like activity of human 20S proteasome beta 2 subunit assessed as hydrolysis of Boc-LRR-AMC fluorogenic substrate measured for 1...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Bio-Science and Technology
Curated by ChEMBL
Institute of Bio-Science and Technology
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-LLVY-MCA as substrate measured for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute of Bio-Science and Technology
Curated by ChEMBL
Institute of Bio-Science and Technology
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate measured for 1 hr b...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute of Bio-Science and Technology
Curated by ChEMBL
Institute of Bio-Science and Technology
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate measured for 1 hr b...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Waseda University
Curated by ChEMBL
Waseda University
Curated by ChEMBL
Affinity DataIC50: 410nMAssay Description:Inhibition of human LSD1 using H3K4 peptide as substrate by peroxidase-coupled assayMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute of Bio-Science and Technology
Curated by ChEMBL
Institute of Bio-Science and Technology
Curated by ChEMBL
Affinity DataIC50: 430nMAssay Description:Inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate measured for 1 hr b...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Waseda University
Curated by ChEMBL
Waseda University
Curated by ChEMBL
Affinity DataIC50: 480nMAssay Description:Inhibition of human LSD1 using H3K4 peptide as substrate by peroxidase-coupled assayMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Bio-Science and Technology
Curated by ChEMBL
Institute of Bio-Science and Technology
Curated by ChEMBL
Affinity DataIC50: 580nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta 5 subunit assessed as hydrolysis of succinyl-LLVY-AMC fluorogenic substrate mea...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Waseda University
Curated by ChEMBL
Waseda University
Curated by ChEMBL
Affinity DataIC50: 580nMAssay Description:Inhibition of human LSD1 using H3K4 peptide as substrate by peroxidase-coupled assayMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute of Bio-Science and Technology
Curated by ChEMBL
Institute of Bio-Science and Technology
Curated by ChEMBL
Affinity DataIC50: 630nMAssay Description:Inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate measured for 1 hr b...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Bio-Science and Technology
Curated by ChEMBL
Institute of Bio-Science and Technology
Curated by ChEMBL
Affinity DataIC50: 640nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta 5 subunit assessed as hydrolysis of succinyl-LLVY-AMC fluorogenic substrate mea...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Bio-Science and Technology
Curated by ChEMBL
Institute of Bio-Science and Technology
Curated by ChEMBL
Affinity DataIC50: 670nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta 5 subunit assessed as hydrolysis of succinyl-LLVY-AMC fluorogenic substrate mea...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Nagahama Institute of Bio-Science and Technology
Curated by ChEMBL
Nagahama Institute of Bio-Science and Technology
Curated by ChEMBL
Affinity DataIC50: 690nMAssay Description:Inhibition of trypsin-like activity of human 20S proteasome beta 2 subunit assessed as hydrolysis of Boc-LRR-AMC fluorogenic substrate measured for 1...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute of Bio-Science and Technology
Curated by ChEMBL
Institute of Bio-Science and Technology
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibition of PGPH activity of human 20S proteasome using Z-LLE-MCA as substrate measured for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute of Bio-Science and Technology
Curated by ChEMBL
Institute of Bio-Science and Technology
Curated by ChEMBL
Affinity DataIC50: 720nMAssay Description:Inhibition of PGPH activity of human 20S proteasome using Z-LLE-MCA as substrate measured for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Bio-Science and Technology
Curated by ChEMBL
Institute of Bio-Science and Technology
Curated by ChEMBL
Affinity DataIC50: 750nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta 5 subunit assessed as hydrolysis of succinyl-LLVY-AMC fluorogenic substrate mea...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute of Bio-Science and Technology
Curated by ChEMBL
Institute of Bio-Science and Technology
Curated by ChEMBL
Affinity DataIC50: 770nMAssay Description:Inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate measured for 1 hr b...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute of Bio-Science and Technology
Curated by ChEMBL
Institute of Bio-Science and Technology
Curated by ChEMBL
Affinity DataIC50: 790nMAssay Description:Inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate measured for 1 hr b...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
Kyoto Prefectural University of Medicine
Curated by ChEMBL
Kyoto Prefectural University of Medicine
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of KDM4A (unknown origin) using H3K9me3 peptide and 2-oxoglutarate as substrate after 1 hr by FDH-coupled assayMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Bio-Science and Technology
Curated by ChEMBL
Institute of Bio-Science and Technology
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta 5 subunit assessed as hydrolysis of succinyl-LLVY-AMC fluorogenic substrate mea...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute of Bio-Science and Technology
Curated by ChEMBL
Institute of Bio-Science and Technology
Curated by ChEMBL
Affinity DataIC50: 840nMAssay Description:Inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate measured for 1 hr b...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute of Bio-Science and Technology
Curated by ChEMBL
Institute of Bio-Science and Technology
Curated by ChEMBL
Affinity DataIC50: 870nMAssay Description:Inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate measured for 1 hr b...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Nagahama Institute of Bio-Science and Technology
Curated by ChEMBL
Nagahama Institute of Bio-Science and Technology
Curated by ChEMBL
Affinity DataIC50: 880nMAssay Description:Inhibition of trypsin-like activity of human 20S proteasome beta 2 subunit assessed as hydrolysis of Boc-LRR-AMC fluorogenic substrate measured for 1...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute of Bio-Science and Technology
Curated by ChEMBL
Institute of Bio-Science and Technology
Curated by ChEMBL
Affinity DataIC50: 890nMAssay Description:Inhibition of PGPH activity of human 20S proteasome using Z-LLE-MCA as substrate measured for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Bio-Science and Technology
Curated by ChEMBL
Institute of Bio-Science and Technology
Curated by ChEMBL
Affinity DataIC50: 890nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-LLVY-MCA as substrate measured for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute of Bio-Science and Technology
Curated by ChEMBL
Institute of Bio-Science and Technology
Curated by ChEMBL
Affinity DataIC50: 890nMAssay Description:Inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate measured for 1 hr b...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Bio-Science and Technology
Curated by ChEMBL
Institute of Bio-Science and Technology
Curated by ChEMBL
Affinity DataIC50: 890nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-LLVY-MCA as substrate measured for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute of Bio-Science and Technology
Curated by ChEMBL
Institute of Bio-Science and Technology
Curated by ChEMBL
Affinity DataIC50: 890nMAssay Description:Inhibition of PGPH activity of human 20S proteasome using Z-LLE-MCA as substrate measured for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Bio-Science and Technology
Curated by ChEMBL
Institute of Bio-Science and Technology
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta 5 subunit assessed as hydrolysis of succinyl-LLVY-AMC fluorogenic substrate mea...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute of Bio-Science and Technology
Curated by ChEMBL
Institute of Bio-Science and Technology
Curated by ChEMBL
Affinity DataIC50: 910nMAssay Description:Inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate measured for 1 hr b...More data for this Ligand-Target Pair