Compile Data Set for Download or QSAR
Found 128 with Last Name = 'schnitzer' and Initial = 'r'
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50581660(CHEMBL1714813)copy SMILES
Affinity DataIC50: 1nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154MXQPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519121(CHEMBL4436264 | US11304929, Example 03-005)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519122(CHEMBL4467246 | US11304929, Example 03-009)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519130(CHEMBL4520837 | US11304929, Example 03-006)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519121(CHEMBL4436264 | US11304929, Example 03-005)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519122(CHEMBL4467246 | US11304929, Example 03-009)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519137(CHEMBL4539932)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of His6-tagged PHGDH (unknown origin) expressed in Escherichia coli BL21 assessed as effect on NADH fluorescence incubated for 60 mins usi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50505841(CHEMBL4532034 | US11174245, # I-018)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of GST-fusion tagged EGFR L858R/T790M/C797S triple mutant (unknown origin) (696 to 1022 residues) expressed in insect cells assessed as de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD14ZQPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519120(CHEMBL4438014)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519114(CHEMBL4458393 | US11304929, Example 04-001)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519093(CHEMBL4522467)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519150(CHEMBL4594097)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519131(CHEMBL4518579 | US11304929, Example 01-002)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of PHGDH in human MDA-MB-468 cells assessed as reduction in [13C]-serine incubated for 1 hr using [13C]glucose as substrate by LC-MS/MS an...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519090(CHEMBL4469992)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519118(CHEMBL4473052)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetSon of sevenless homolog 1(Homo sapiens (Human))TBA
LigandPNGBDBM50581659(CHEMBL4519023 | US20230339952, Comparative Compoun...)copy SMILES
Affinity DataIC50: 36nMAssay Description:Inhibition of SOS1-mediated proliferation of human DLD-1 cells assessed as proliferation incubated for 5 to 14 days by AlamarBlue based 3D proliferat...More data for this Ligand-Target Pair
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519117(CHEMBL4474620)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519116(CHEMBL4457646)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519129(CHEMBL4560125)copy SMILEScopy InChI
Affinity DataIC50: 61nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519136(CHEMBL4565713)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519092(CHEMBL4437057)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519119(CHEMBL4444192)copy SMILEScopy InChI
Affinity DataIC50: 81nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetEpidermal growth factor receptor(Mus musculus)
Boehringer Ingelheim RCV GmbH & Co KG

Curated by ChEMBL
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)copy SMILEScopy InChI
Affinity DataIC50: 81nMAssay Description:Inhibition of wild type EGFR in mouse BAF3 cells assessed as reduction in cell proliferation incubated for 72 hrs by Celltiter-Glo luminescent cell v...More data for this Ligand-Target Pair
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519120(CHEMBL4438014)copy SMILEScopy InChI
Affinity DataIC50: 95nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519134(CHEMBL4588817)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519108(CHEMBL4446190)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519153(CHEMBL4460522)copy SMILEScopy InChI
Affinity DataIC50: 123nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetEpidermal growth factor receptor(Mus musculus)
Boehringer Ingelheim RCV GmbH & Co KG

Curated by ChEMBL
LigandPNGBDBM50505838(CHEMBL4537790)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of wild type EGFR in mouse BAF3 cells assessed as reduction in cell proliferation incubated for 72 hrs by Celltiter-Glo luminescent cell v...More data for this Ligand-Target Pair
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519090(CHEMBL4469992)copy SMILEScopy InChI
Affinity DataIC50: 228nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519150(CHEMBL4594097)copy SMILEScopy InChI
Affinity DataIC50: 246nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519093(CHEMBL4522467)copy SMILEScopy InChI
Affinity DataIC50: 249nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519149(CHEMBL4446511)copy SMILEScopy InChI
Affinity DataIC50: 254nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50505836(CHEMBL4434788 | US11174245, # I-064)copy SMILEScopy InChI
Affinity DataIC50: 267nMAssay Description:Inhibition of GST-fusion tagged EGFR L858R/T790M/C797S triple mutant (unknown origin) (696 to 1022 residues) expressed in insect cells assessed as de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD14ZQPubMed
TargetEpidermal growth factor receptor(Mus musculus)
Boehringer Ingelheim RCV GmbH & Co KG

Curated by ChEMBL
LigandPNGBDBM50505845(CHEMBL4566193)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:Inhibition of wild type EGFR in mouse BAF3 cells assessed as reduction in cell proliferation incubated for 72 hrs by Celltiter-Glo luminescent cell v...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD14ZQPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519148(CHEMBL4528650)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519118(CHEMBL4473052)copy SMILEScopy InChI
Affinity DataIC50: 301nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519129(CHEMBL4560125)copy SMILEScopy InChI
Affinity DataIC50: 341nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519116(CHEMBL4457646)copy SMILEScopy InChI
Affinity DataIC50: 345nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50505843(CHEMBL4449589 | US11174245, # I-235)copy SMILEScopy InChI
Affinity DataIC50: 353nMAssay Description:Inhibition of GST-fusion tagged EGFR L858R/T790M/C797S triple mutant (unknown origin) (696 to 1022 residues) expressed in insect cells assessed as de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD14ZQPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519101(CHEMBL4435368)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519117(CHEMBL4474620)copy SMILEScopy InChI
Affinity DataIC50: 412nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50505839(CHEMBL4525935 | US11174245, # I-001)copy SMILEScopy InChI
Affinity DataIC50: 519nMAssay Description:Inhibition of GST-fusion tagged EGFR L858R/T790M/C797S triple mutant (unknown origin) (696 to 1022 residues) expressed in insect cells assessed as de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD14ZQPubMed
TargetEpidermal growth factor receptor(Mus musculus)
Boehringer Ingelheim RCV GmbH & Co KG

Curated by ChEMBL
LigandPNGBDBM50505841(CHEMBL4532034 | US11174245, # I-018)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Inhibition of wild type EGFR in mouse BAF3 cells assessed as reduction in cell proliferation incubated for 72 hrs by Celltiter-Glo luminescent cell v...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD14ZQPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519119(CHEMBL4444192)copy SMILEScopy InChI
Affinity DataIC50: 714nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519092(CHEMBL4437057)copy SMILEScopy InChI
Affinity DataIC50: 746nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519096(CHEMBL4561620)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519128(CHEMBL4520181)copy SMILEScopy InChI
Affinity DataIC50: 824nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519103(CHEMBL4476414)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetEpidermal growth factor receptor(Mus musculus)
Boehringer Ingelheim RCV GmbH & Co KG

Curated by ChEMBL
LigandPNGBDBM50505846(CHEMBL4562138)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of wild type EGFR in mouse BAF3 cells assessed as reduction in cell proliferation incubated for 72 hrs by Celltiter-Glo luminescent cell v...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD14ZQPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519153(CHEMBL4460522)copy SMILEScopy InChI
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
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