Compile Data Set for Download or QSAR
Found 243 with Last Name = 'taub' and Initial = 'r'
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Hoffmann-La Roche, Inc.

Curated by ChEMBL
LigandPNGBDBM50371874(CHEMBL257733)copy SMILEScopy InChI
Affinity DataKi:  0.5nMAssay Description:Binding affinity to MCHR1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M909HRPubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Hoffmann-La Roche, Inc.

Curated by ChEMBL
LigandPNGBDBM50371872(CHEMBL257280)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Binding affinity to MCHR1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M909HRPubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Hoffmann-La Roche, Inc.

Curated by ChEMBL
LigandPNGBDBM50371868(CHEMBL269939)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:Binding affinity to MCHR1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M909HRPubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Hoffmann-La Roche, Inc.

Curated by ChEMBL
LigandPNGBDBM50371871(CHEMBL255112)copy SMILEScopy InChI
Affinity DataKi:  5.20nMAssay Description:Binding affinity to MCHR1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M909HRPubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Hoffmann-La Roche, Inc.

Curated by ChEMBL
LigandPNGBDBM50371866(CHEMBL257906)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Binding affinity to MCHR1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M909HRPubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50074364(CHEMBL350356 | N*2*-(2-Bromo-4-isopropyl-phenyl)-N...)copy SMILEScopy InChI
Affinity DataKi:  18nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FT6PubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Hoffmann-La Roche, Inc.

Curated by ChEMBL
LigandPNGBDBM50371869(CHEMBL270151)copy SMILEScopy InChI
Affinity DataKi:  20nMAssay Description:Binding affinity to MCHR1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M909HRPubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Hoffmann-La Roche, Inc.

Curated by ChEMBL
LigandPNGBDBM50371873(CHEMBL403730)copy SMILEScopy InChI
Affinity DataKi:  25nMAssay Description:Binding affinity to MCHR1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M909HRPubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Hoffmann-La Roche, Inc.

Curated by ChEMBL
LigandPNGBDBM50371870(CHEMBL258260)copy SMILEScopy InChI
Affinity DataKi:  31nMAssay Description:Binding affinity to MCHR1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M909HRPubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Hoffmann-La Roche, Inc.

Curated by ChEMBL
LigandPNGBDBM50371867(CHEMBL257905)copy SMILEScopy InChI
Affinity DataKi:  47nMAssay Description:Binding affinity to MCHR1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M909HRPubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50155982(8-(Butyl-ethyl-amino)-4-(2-chloro-4-methoxy-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FT6PubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50155974(8-(Butyl-ethyl-amino)-4-(2,4-dichloro-phenyl)-6-me...)copy SMILEScopy InChI
Affinity DataIC50: 0.490nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FT6PubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50155964(8-(Butyl-ethyl-amino)-4-(2-chloro-5-fluoro-4-metho...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FT6PubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50155967(4-(2-Bromo-4-isopropyl-phenyl)-8-(butyl-ethyl-amin...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FT6PubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM20977(8-[butyl(ethyl)amino]-4-(2,6-dimethoxypyridin-3-yl...)copy SMILEScopy InChI
Affinity DataIC50: 0.820nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FT6PubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50155979(8-(Butyl-ethyl-amino)-4-(2-chloro-4-isopropyl-phen...)copy SMILEScopy InChI
Affinity DataIC50: 0.910nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FT6PubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM20973(8-[butyl(ethyl)amino]-4-(4-methoxy-2-methylphenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 0.920nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FT6PubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50155975(3-Chloro-4-(8-dipropylamino-6-methyl-2-oxo-2,3-dih...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FT6PubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50155973(4-(2-Chloro-5-fluoro-4-methoxy-phenyl)-8-(ethyl-is...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FT6PubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50155960(3-Chloro-4-[8-(cyclobutylmethyl-propyl-amino)-6-me...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FT6PubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50155959(4-[8-(Butyl-ethyl-amino)-6-methyl-2-oxo-2,3-dihydr...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FT6PubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50155965(4-(2-Chloro-4-isopropyl-phenyl)-8-[(2-methoxy-ethy...)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FT6PubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50155977(4-[8-(Butyl-ethyl-amino)-6-methyl-2-oxo-2,3-dihydr...)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FT6PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50018759(CHEMBL3291350)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7CPFPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50018760(CHEMBL3291357)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7CPFPubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50155966(4-(2-Bromo-4-isopropyl-phenyl)-8-(ethyl-furan-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 4.10nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FT6PubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50155961(8-(Butyl-ethyl-amino)-4-(6-methoxy-2-methyl-pyridi...)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FT6PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50018761(CHEMBL3291348)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7CPFPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50018761(CHEMBL3291348)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7CPFPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50018793(CHEMBL3291344)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7CPFPubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50341785((1R,2R)-2-(3'-fluoro-4'-(3-phenylureido)biphenylca...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of human DGAT1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S182TQPubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50155981(4-(2-Bromo-phenyl)-8-(butyl-ethyl-amino)-6-methyl-...)copy SMILEScopy InChI
Affinity DataIC50: 7.10nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FT6PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50018759(CHEMBL3291350)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7CPFPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50018795(CHEMBL3291339)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7CPFPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50018769(CHEMBL3291346)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7CPFPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50018797(CHEMBL3291345)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7CPFPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50018760(CHEMBL3291357)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7CPFPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50018794(CHEMBL3291340)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7CPFPubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50155969(2-[8-(Butyl-ethyl-amino)-6-methyl-2-oxo-2,3-dihydr...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FT6PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50018793(CHEMBL3291344)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7CPFPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50018769(CHEMBL3291346)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7CPFPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50018798(CHEMBL3291342)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7CPFPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50018797(CHEMBL3291345)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7CPFPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50018799(CHEMBL3291347)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7CPFPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50018802(CHEMBL3291354)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7CPFPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50018803(CHEMBL3291358)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7CPFPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50018794(CHEMBL3291340)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7CPFPubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50341766(2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Aci...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S182TQPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50018799(CHEMBL3291347)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7CPFPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50018795(CHEMBL3291339)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7CPFPubMed
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