Compile Data Set for Download or QSAR
Found 16 with Last Name = 'tsai' and Initial = 'r'
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Universit£ di Firenze

Curated by ChEMBL
LigandPNGBDBM50057499((R)-8-Chloro-4,10b-dimethyl-1,4,4a,5,6,10b-hexahyd...)copy SMILEScopy InChI
Affinity DataKi:  9nMAssay Description:Compound was evaluated for the inhibition of human Steroid 5-alpha-reductase type 1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CC1169PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
Universit£ di Firenze

Curated by ChEMBL
LigandPNGBDBM50057501((S)-7-Chloro-4a-methyl-3,4,4a,9-tetrahydro-phenant...)copy SMILEScopy InChI
Affinity DataKi:  260nMAssay Description:Compound was evaluated for the inhibition of human Steroid 5-alpha-reductase type 2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CC1169PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Universit£ di Firenze

Curated by ChEMBL
LigandPNGBDBM50072190((R)-8-Chloro-4,10b-dimethyl-1,5,6,10b-tetrahydro-2...)copy SMILEScopy InChI
Affinity DataKi:  920nMAssay Description:Compound was evaluated for the inhibition of human Steroid 5-alpha-reductase type 1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CC1169PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
Universit£ di Firenze

Curated by ChEMBL
LigandPNGBDBM50057499((R)-8-Chloro-4,10b-dimethyl-1,4,4a,5,6,10b-hexahyd...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+3nMAssay Description:Compound was evaluated for the inhibition of human Steroid 5-alpha-reductase type 2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CC1169PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Universit£ di Firenze

Curated by ChEMBL
LigandPNGBDBM50057501((S)-7-Chloro-4a-methyl-3,4,4a,9-tetrahydro-phenant...)copy SMILEScopy InChI
Affinity DataKi:  1.20E+3nMAssay Description:Compound was evaluated for the inhibition of human Steroid 5-alpha-reductase type 1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CC1169PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
Universit£ di Firenze

Curated by ChEMBL
LigandPNGBDBM50072190((R)-8-Chloro-4,10b-dimethyl-1,5,6,10b-tetrahydro-2...)copy SMILEScopy InChI
Affinity DataKi:  2.00E+4nMAssay Description:Compound was evaluated for the inhibition of human Steroid 5-alpha-reductase type 2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CC1169PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
Universit£ di Firenze

Curated by ChEMBL
LigandPNGBDBM50334788((17beta-(N-tert-butylcarbamoyl)-4-aza-5alpha-andro...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Compound was evaluated for the inhibition of human Steroid 5-alpha-reductase type 2 receptor from human prostate homogenatesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CC1169PubMedDrugBank
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
Universit£ di Firenze

Curated by ChEMBL
LigandPNGBDBM50072189((7aS,8R)-7a-Methyl-2-oxo-2,3,4,7,7a,8,9,10,10a,10b...)copy SMILEScopy InChI
Affinity DataIC50: 122nMAssay Description:Compound was evaluated for the inhibition of human Steroid 5-alpha-reductase type 2 receptor from human prostate homogenates.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CC1169PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Universit£ di Firenze

Curated by ChEMBL
LigandPNGBDBM50072189((7aS,8R)-7a-Methyl-2-oxo-2,3,4,7,7a,8,9,10,10a,10b...)copy SMILEScopy InChI
Affinity DataIC50: 127nMAssay Description:Compound was evaluated for the inhibition of human Steroid 5-alpha-reductase type 1 from recombinant CHO cells; No inhibition up to 10 uM concentrati...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CC1169PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Universit£ di Firenze

Curated by ChEMBL
LigandPNGBDBM50072191(1,2,5,6-Tetrahydro-pyrido[1,2-a]quinolin-3-one | 1...)copy SMILEScopy InChI
Affinity DataIC50: 298nMAssay Description:Compound was evaluated for the inhibition of human Steroid 5-alpha-reductase type 1 from recombinant CHO cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CC1169PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Universit£ di Firenze

Curated by ChEMBL
LigandPNGBDBM50334788((17beta-(N-tert-butylcarbamoyl)-4-aza-5alpha-andro...)copy SMILEScopy InChI
Affinity DataIC50: 911nMAssay Description:Compound was evaluated for the inhibition of human Steroid 5-alpha-reductase type 1 from recombinant CHO cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CC1169PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM50140172(CHEBI:3962 | CHEMBL140 | Curcumin | US9409845, Tab...)copy SMILEScopy InChI
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of amyloid beta (1 to 42) fibrillization (unknown origin) incubated with agitation for 1 min every hr measured over 80 hrs by thioflavin-T...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7M0RPubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM50467361(CHEMBL197478)copy SMILEScopy InChI
Affinity DataIC50: 4.20E+3nMAssay Description:Disaggregation of amyloid beta (1 to 42 residues) (unknown origin) preformed fibrils incubated with agitation for 1 min every hr measured over 80 hrs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7M0RPubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM50467361(CHEMBL197478)copy SMILEScopy InChI
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of amyloid beta (1 to 42) fibrillization (unknown origin) incubated with agitation for 1 min every hr measured over 80 hrs by thioflavin-T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7M0RPubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Universit£ di Firenze

Curated by ChEMBL
LigandPNGBDBM50072192(3,4,5,6-Tetrahydrobenzo[c]quinolizin-3-(4aH)-one |...)copy SMILEScopy InChI
Affinity DataIC50: 5.13E+3nMAssay Description:Compound was evaluated for the inhibition of human Steroid 5-alpha-reductase type 1 from recombinant CHO cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CC1169PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM4375((2E)-3-(3,4-dihydroxyphenyl)prop-2-enoic acid | (2...)copy SMILEScopy InChI
Affinity DataIC50: 1.56E+4nMAssay Description:Inhibition of amyloid beta (1 to 42) fibrillization (unknown origin) incubated with agitation for 1 min every hr measured over 80 hrs by thioflavin-T...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7M0RPubMed