Compile Data Set for Download or QSAR
Found 57 with Last Name = 'vaughan' and Initial = 'r'
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute on Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50156916((1R)-3beta-(4-bromophenyl)tropane-2beta-carboxylic...)copy SMILEScopy InChI
Affinity DataKi:  0.420nMAssay Description:Displacement of [3H]WIN 35428 from DAT in rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ36SMPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50327157((R)-methyl 2-(3,4-dichlorophenyl)-2-((R)-piperidin...)copy SMILEScopy InChI
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]WIN-35,428 from human DAT expressed in mouse N2A cells after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7BHGPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
National Institute on Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50302225((1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl...)copy SMILEScopy InChI
Affinity DataKi:  2.20nMAssay Description:Inhibition of wild type human SERT expressed in HEK293 GripTite cells pre-incubated for 5 mins followed by [3H]5-HT addition by [3H]5-HT uptake assayMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50388871(CHEMBL2062931)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Displacement of [3H]WIN-35,428 from human DAT expressed in mouse N2A cells after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7BHGPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute on Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50156916((1R)-3beta-(4-bromophenyl)tropane-2beta-carboxylic...)copy SMILEScopy InChI
Affinity DataKi:  4.10nMAssay Description:Displacement of [3H]citaloporam from SERT in rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ36SMPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50334215((+/-)-threo-3-Iodomethylphenidate | CHEMBL1641691)copy SMILEScopy InChI
Affinity DataKi:  4.5nMAssay Description:Displacement of [3H]WIN-35,428 from human DAT expressed in mouse N2A cells after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7BHGPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50334215((+/-)-threo-3-Iodomethylphenidate | CHEMBL1641691)copy SMILEScopy InChI
Affinity DataKi:  4.5nMAssay Description:Displacement of [3H]WIN-35428 from human DAT stably expressed in mouse N2A cells by scintillation countnigMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z9567PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50293605(1-(4-aminophenyl)-2-pyrrolidin-1-yl-pentan-1-one |...)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:Displacement of [3H]WIN35428 from human dopamine transporter expressed in mouse N2A cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1KN6PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute on Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50197206(8-methyl-3beta-(4'-nitro-biphenyl-4-yl)-8-aza-bicy...)copy SMILEScopy InChI
Affinity DataKi:  5.03nMAssay Description:Displacement of [3H]WIN 35428 from DAT in rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ36SMPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50327143((R)-methyl 2-(4-aminophenyl)-2-((R)-piperidin-2-yl...)copy SMILEScopy InChI
Affinity DataKi:  6.30nMAssay Description:Displacement of [3H]WIN-35,428 from human DAT expressed in mouse N2A cells after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7BHGPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50182555(1-(4-methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one ...)copy SMILEScopy InChI
Affinity DataKi:  8nMAssay Description:Displacement of [3H]WIN35428 from human dopamine transporter expressed in mouse N2A cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1KN6PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute on Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50450532(CHEMBL2308105)copy SMILEScopy InChI
Affinity DataKi:  8.5nMAssay Description:The compound was tested for binding affinity towards dopamine transporter in rat caudate putamenMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP538T
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute on Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50197204(3beta-(4'-amino-3'-iodo-biphenyl-4-yl)-8-methyl-8-...)copy SMILEScopy InChI
Affinity DataKi:  8.82nMAssay Description:Displacement of [3H]citaloporam from SERT in rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ36SMPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50388869(CHEMBL2062932)copy SMILEScopy InChI
Affinity DataKi:  9.10nMAssay Description:Displacement of [3H]WIN-35,428 from human DAT expressed in mouse N2A cells after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7BHGPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute on Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50197207(3beta-(4'-amino-biphenyl-4-yl)-8-methyl-8-aza-bicy...)copy SMILEScopy InChI
Affinity DataKi:  12.9nMAssay Description:Displacement of [3H]WIN 35428 from DAT in rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ36SMPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50327148((R)-methyl 2-(4-iodophenyl)-2-((R)-piperidin-2-yl)...)copy SMILEScopy InChI
Affinity DataKi:  14nMAssay Description:Displacement of [3H]WIN-35428 from human DAT stably expressed in mouse N2A cells by scintillation countnigMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z9567PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute on Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50197205(3beta-(4'-azido-3'-iodo-biphenyl-4-yl)-8-methyl-8-...)copy SMILEScopy InChI
Affinity DataKi:  15.1nMAssay Description:Displacement of [3H]WIN 35428 from DAT in rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ36SMPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50062915(CHEMBL827 | METHYLPHENIDATE | methyl (2R)-phenyl[(...)copy SMILEScopy InChI
Affinity DataKi:  16nMAssay Description:Displacement of [3H]WIN-35,428 from human DAT expressed in mouse N2A cells after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7BHGPubMedDrugBank
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute on Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50450529(CHEMBL3084934)copy SMILEScopy InChI
Affinity DataKi:  20nMAssay Description:The compound was tested for binding affinity towards dopamine transporter in rat caudate putamenMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP538T
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
National Institute on Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50093443(CHEMBL3586683)copy SMILEScopy InChI
Affinity DataKi:  24nMAssay Description:Inhibition of wild type human SERT expressed in HEK293 GripTite cells pre-incubated for 5 mins followed by [3H]5-HT addition by [3H]5-HT uptake assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8PFCPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50062915(CHEMBL827 | METHYLPHENIDATE | methyl (2R)-phenyl[(...)copy SMILEScopy InChI
Affinity DataKi:  25nMAssay Description:Displacement of [3H]WIN-35428 from human DAT stably expressed in mouse N2A cells by scintillation countnigMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z9567PubMedDrugBank
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50293604(1-(4-amino-3-iodophenyl)-2-pyrrolidin-1-yl-pentan-...)copy SMILEScopy InChI
Affinity DataKi:  28nMAssay Description:Displacement of [3H]WIN35428 from human dopamine transporter expressed in mouse N2A cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1KN6PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute on Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50450531(CHEMBL3084929)copy SMILEScopy InChI
Affinity DataKi:  30nMAssay Description:The compound was tested for binding affinity towards dopamine transporter in rat caudate putamenMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP538T
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50388870(CHEMBL2062933)copy SMILEScopy InChI
Affinity DataKi:  35nMAssay Description:Displacement of [3H]WIN-35,428 from human DAT expressed in mouse N2A cells after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7BHGPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
National Institute on Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50093442(CHEMBL3586682)copy SMILEScopy InChI
Affinity DataKi:  38nMAssay Description:Inhibition of wild type human SERT expressed in HEK293 GripTite cells pre-incubated for 5 mins followed by [3H]5-HT addition by [3H]5-HT uptake assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8PFCPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute on Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50197206(8-methyl-3beta-(4'-nitro-biphenyl-4-yl)-8-aza-bicy...)copy SMILEScopy InChI
Affinity DataKi:  51nMAssay Description:Displacement of [3H]citaloporam from SERT in rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ36SMPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50327141((R)-methyl 2-(4-nitrophenyl)-2-((R)-piperidin-2-yl...)copy SMILEScopy InChI
Affinity DataKi:  77nMAssay Description:Displacement of [3H]WIN-35,428 from human DAT expressed in mouse N2A cells after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7BHGPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50293606(1-(4-azio-3-iodophenyl)-2-pyrroldin-1-yl-pentan-1-...)copy SMILEScopy InChI
Affinity DataKi:  78nMAssay Description:Displacement of [3H]WIN35428 from human dopamine transporter expressed in mouse N2A cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1KN6PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute on Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50197205(3beta-(4'-azido-3'-iodo-biphenyl-4-yl)-8-methyl-8-...)copy SMILEScopy InChI
Affinity DataKi:  109nMAssay Description:Displacement of [3H]citaloporam from SERT in rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ36SMPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute on Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50197204(3beta-(4'-amino-3'-iodo-biphenyl-4-yl)-8-methyl-8-...)copy SMILEScopy InChI
Affinity DataKi:  134nMAssay Description:Displacement of [3H]WIN 35428 from DAT in rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ36SMPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute on Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50450530(CHEMBL3084932)copy SMILEScopy InChI
Affinity DataKi:  159nMAssay Description:The compound was tested for binding affinity towards dopamine transporter in rat caudate putamenMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP538T
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
National Institute on Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50093441(CHEMBL3586681)copy SMILEScopy InChI
Affinity DataKi:  227nMAssay Description:Inhibition of wild type human SERT expressed in HEK293 GripTite cells pre-incubated for 5 mins followed by [3H]5-HT addition by [3H]5-HT uptake assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8PFCPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50334214((+/-)-threo-N-(p-Azido-benzyl)-4-iodomethylphenida...)copy SMILEScopy InChI
Affinity DataKi:  363nMAssay Description:Displacement of [3H]WIN-35428 from human DAT stably expressed in mouse N2A cells by scintillation countnigMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z9567PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50048392(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)copy SMILEScopy InChI
Affinity DataKi:  441nMAssay Description:Displacement of [3H]WIN35428 from human dopamine transporter expressed in mouse N2A cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1KN6PubMedDrugBank
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50334212((+/-)-threo-N-(o-Azido-benzyl)-4-iodomethylphenida...)copy SMILEScopy InChI
Affinity DataKi:  517nMAssay Description:Displacement of [3H]WIN-35428 from human DAT stably expressed in mouse N2A cells by scintillation countnigMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z9567PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50334211((+/-)-threo-N-(p-Azido-benzyl)-3-iodomethylphenida...)copy SMILEScopy InChI
Affinity DataKi:  658nMAssay Description:Displacement of [3H]WIN-35428 from human DAT stably expressed in mouse N2A cells by scintillation countnigMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z9567PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute on Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50197207(3beta-(4'-amino-biphenyl-4-yl)-8-methyl-8-aza-bicy...)copy SMILEScopy InChI
Affinity DataKi:  1.07E+3nMAssay Description:Displacement of [3H]citaloporam from SERT in rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ36SMPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50334209((+/-)-threo-N-(o-Azido-benzyl)-3-iodomethylphenida...)copy SMILEScopy InChI
Affinity DataKi:  1.11E+3nMAssay Description:Displacement of [3H]WIN-35428 from human DAT stably expressed in mouse N2A cells by scintillation countnigMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z9567PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50334210((+/-)-threo-N-(m-Azido-benzyl)-3-iodomethylphenida...)copy SMILEScopy InChI
Affinity DataKi:  2.06E+3nMAssay Description:Displacement of [3H]WIN-35428 from human DAT stably expressed in mouse N2A cells by scintillation countnigMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z9567PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50334213((+/-)-threo-N-(m-Azido-benzyl)-4-iodomethylphenida...)copy SMILEScopy InChI
Affinity DataKi:  2.75E+3nMAssay Description:Displacement of [3H]WIN-35428 from human DAT stably expressed in mouse N2A cells by scintillation countnigMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z9567PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50363131(CHEMBL1946574)copy SMILEScopy InChI
Affinity DataKi:  3.07E+3nMAssay Description:Displacement of [3H]WIN-35,428 from human DAT expressed in N2A cells after 15 mins by photoaffinity labelingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6CN3PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50293605(1-(4-aminophenyl)-2-pyrrolidin-1-yl-pentan-1-one |...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of [3H]dopamine uptake at human dopamine transporter expressed in mouse N2A cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1KN6PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50327148((R)-methyl 2-(4-iodophenyl)-2-((R)-piperidin-2-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in mouse N2A cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z9567PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50334215((+/-)-threo-3-Iodomethylphenidate | CHEMBL1641691)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in mouse N2A cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z9567PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50182555(1-(4-methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one ...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of [3H]dopamine uptake at human dopamine transporter expressed in mouse N2A cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1KN6PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50062915(CHEMBL827 | METHYLPHENIDATE | methyl (2R)-phenyl[(...)copy SMILEScopy InChI
Affinity DataIC50: 156nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in mouse N2A cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z9567PubMedDrugBank
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50293604(1-(4-amino-3-iodophenyl)-2-pyrrolidin-1-yl-pentan-...)copy SMILEScopy InChI
Affinity DataIC50: 175nMAssay Description:Inhibition of [3H]dopamine uptake at human dopamine transporter expressed in mouse N2A cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1KN6PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50293606(1-(4-azio-3-iodophenyl)-2-pyrroldin-1-yl-pentan-1-...)copy SMILEScopy InChI
Affinity DataIC50: 264nMAssay Description:Inhibition of [3H]dopamine uptake at human dopamine transporter expressed in mouse N2A cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1KN6PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI
Affinity DataIC50: 392nMAssay Description:Displacement of [3H]CFT from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1MJ8PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1MJ8PubMed
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