Affinity DataIC50: 4nMAssay Description:Inhibition of human beta5 20S immunoproteasome using Ac-ANW-AMC as substrateMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Veterans Affairs Medical Center
Curated by ChEMBL
Veterans Affairs Medical Center
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Inhibition of [3H]norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Veterans Affairs Medical Center
Curated by ChEMBL
Veterans Affairs Medical Center
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of [3H]5HT uptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of human beta5 20S immunoproteasome using Ac-ANW-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of human beta5 20S immunoproteasome using Ac-ANW-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Inhibition of human beta5 20S immunoproteasome using Ac-ANW-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Inhibition of human beta5 20S immunoproteasome using Ac-ANW-AMC as substrateMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Veterans Affairs Medical Center
Curated by ChEMBL
Veterans Affairs Medical Center
Curated by ChEMBL
Affinity DataIC50: 64nMAssay Description:Inhibition of [3H]5HT uptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 66nMAssay Description:Displacement of [3H]pyrilamine from human histamine receptor subtype 1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 73nMAssay Description:Inhibition of human beta5 20S immunoproteasome using Ac-ANW-AMC as substrateMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Veterans Affairs Medical Center
Curated by ChEMBL
Veterans Affairs Medical Center
Curated by ChEMBL
Affinity DataIC50: 74nMAssay Description:Inhibition of [3H]norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of human beta5 20S immunoproteasome using Ac-ANW-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of human beta5 20S constitutive proteasome using suc-LLVY-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 112nMAssay Description:Inhibition of human beta5 20S immunoproteasome using Ac-ANW-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 128nMAssay Description:Inhibition of human beta5 20S immunoproteasome using Ac-ANW-AMC as substrateMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Veterans Affairs Medical Center
Curated by ChEMBL
Veterans Affairs Medical Center
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 169nMAssay Description:Inhibition of human beta5 20S immunoproteasome using Ac-ANW-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 179nMAssay Description:Inhibition of human beta5 20S immunoproteasome using Ac-ANW-AMC as substrateMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Veterans Affairs Medical Center
Curated by ChEMBL
Veterans Affairs Medical Center
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of [3H]5HT uptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 195nMAssay Description:Inhibition of human beta5 20S immunoproteasome using Ac-ANW-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of human beta5 20S immunoproteasome using Ac-ANW-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Inhibition of CYP2D6 (unknown origin) by UPLC-MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Inhibition of CYP2C19 (unknown origin) by UPLC-MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Inhibition of CYP2C9 (unknown origin) by UPLC-MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Inhibition of CYP1A2 (unknown origin) using phenacetin O-deethylation by UPLC-MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 384nMAssay Description:Inhibition of human beta5 20S immunoproteasome using Ac-ANW-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 409nMAssay Description:Inhibition of human beta5 20S constitutive proteasome using suc-LLVY-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 430nMAssay Description:Inhibition of human beta5 20S constitutive proteasome using suc-LLVY-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 475nMAssay Description:Inhibition of human beta5 20S immunoproteasome using Ac-ANW-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 506nMAssay Description:Inhibition of human beta5 20S constitutive proteasome using suc-LLVY-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 540nMAssay Description:Inhibition of human beta5 20S constitutive proteasome using suc-LLVY-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 763nMAssay Description:Inhibition of human beta5 20S immunoproteasome using Ac-ANW-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of human beta5 20S constitutive proteasome using suc-LLVY-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.14E+3nMAssay Description:Inhibition of human beta5 20S constitutive proteasome using suc-LLVY-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human beta5 20S immunoproteasome using Ac-ANW-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.41E+3nMAssay Description:Inhibition of human beta5 20S constitutive proteasome using suc-LLVY-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin) by UPLC-MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin) by UPLC-MS analysisMore data for this Ligand-Target Pair