Found 42 with Last Name = 'de melo reis' and Initial = 'ra' 
Affinity DataIC50: 5.30nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of ATP-induced ethidium iodide uptake preincubated for 10...More data for this Ligand-Target Pair
Affinity DataIC50: 6.60nMAssay Description:Tested for inhibitory potency against rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Instituto de Tecnologia em F£rmacos
Curated by ChEMBL
Instituto de Tecnologia em F£rmacos
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Tested for inhibitory potency against rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619 induced platelet aggregation in human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619 induced platelet aggregation in human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619 induced contraction of rat isolated thoracic aortic stripMore data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Antagonist activity at P2X7 receptor in Swiss mouse peritoneal macrophages assessed as inhibition of BzATP-induced current at holding potential of -6...More data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Antagonist activity at P2X7 receptor in Swiss mouse peritoneal macrophages assessed as inhibition of BzATP-induced current at holding potential of -6...More data for this Ligand-Target Pair
Affinity DataIC50: 59nMAssay Description:Antagonist activity at P2X7 receptor in Swiss mouse peritoneal macrophages assessed as inhibition of BzATP-induced ethidium iodide uptake after 30 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 63nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619 induced contraction of rat isolated thoracic aortic stripMore data for this Ligand-Target Pair
Affinity DataIC50: 67nMAssay Description:Tested for inhibitory potency against rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 67nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of ATP-induced IL-1beta release preincubated for 30 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 69nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619 induced contraction of rat isolated thoracic aortic stripMore data for this Ligand-Target Pair
Affinity DataIC50: 81nMAssay Description:Antagonist activity at P2X7 receptor in Swiss mouse peritoneal macrophages assessed as inhibition of ATP-induced current at holding potential of -60 ...More data for this Ligand-Target Pair
Affinity DataIC50: 82nMAssay Description:Evaluated for the antagonistic activity against Serotonin 5-hydroxytryptamine 4 receptor in non-electrically stimulated guinea-pig ileum.More data for this Ligand-Target Pair
Affinity DataIC50: 83nMAssay Description:Antagonist activity at P2X7 receptor in Swiss mouse peritoneal macrophages assessed as inhibition of ATP-induced propidium iodide uptake after 25 min...More data for this Ligand-Target Pair
Affinity DataIC50: 86nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619 induced platelet aggregation in human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 89nMAssay Description:Tested for inhibitory potency against rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 91nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619 induced contraction of rat isolated thoracic aortic stripMore data for this Ligand-Target Pair
Affinity DataIC50: 96nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619 induced contraction of rat isolated thoracic aortic stripMore data for this Ligand-Target Pair
Affinity DataIC50: 103nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619 induced platelet aggregation in human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 103nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619 induced contraction of rat isolated thoracic aortic stripMore data for this Ligand-Target Pair
Affinity DataIC50: 107nMAssay Description:Antagonist activity at P2X7 receptor in Swiss mouse peritoneal macrophages assessed as inhibition of ATP-induced propidium iodide uptake after 25 min...More data for this Ligand-Target Pair
Affinity DataIC50: 108nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619 induced contraction of rat isolated thoracic aortic stripMore data for this Ligand-Target Pair
Affinity DataIC50: 109nMAssay Description:Antagonist activity at P2X7 receptor in Swiss mouse peritoneal macrophages assessed as inhibition of ATP-induced current at holding potential of -60 ...More data for this Ligand-Target Pair
Affinity DataIC50: 112nMAssay Description:Tested for inhibitory potency against rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 167nMAssay Description:Antagonist activity at P2X7 receptor in Swiss mouse peritoneal macrophages assessed as inhibition of ATP-induced propidium iodide uptake after 25 min...More data for this Ligand-Target Pair
Affinity DataIC50: 316nMAssay Description:Tested for inhibitory potency against rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 317nMAssay Description:Tested for inhibitory potency against rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 341nMAssay Description:Antagonist activity at P2X7 receptor in Swiss mouse peritoneal macrophages assessed as inhibition of ATP-induced current at holding potential of -60 ...More data for this Ligand-Target Pair
Affinity DataIC50: 343nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619 induced platelet aggregation in human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 349nMAssay Description:Antagonist activity at P2X7 receptor in Swiss mouse peritoneal macrophages assessed as inhibition of ATP-induced propidium iodide uptake after 25 min...More data for this Ligand-Target Pair
Affinity DataIC50: 407nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619 induced platelet aggregation in human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 432nMAssay Description:Compound was evaluated to inactivate the bacterial AdoMet-DC; value ranges from 3.8 to 39.6 uMMore data for this Ligand-Target Pair
Affinity DataIC50: 457nMAssay Description:Antagonist activity at P2X7 receptor in Swiss mouse peritoneal macrophages assessed as inhibition of ATP-induced current at holding potential of -60 ...More data for this Ligand-Target Pair
Affinity DataIC50: 478nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of ATP-induced ethidium iodide uptake preincubated for 10...More data for this Ligand-Target Pair
Affinity DataIC50: 488nMAssay Description:Antagonist activity at P2X7 receptor in Swiss mouse peritoneal macrophages assessed as inhibition of ATP-induced propidium iodide uptake after 25 min...More data for this Ligand-Target Pair
Affinity DataIC50: 522nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of ATP-induced ethidium iodide uptake preincubated for 10...More data for this Ligand-Target Pair
Affinity DataIC50: 552nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619 induced contraction of rat isolated thoracic aortic stripMore data for this Ligand-Target Pair
Affinity DataIC50: 621nMAssay Description:Tested for inhibitory potency against rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 897nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of ATP-induced ethidium iodide uptake preincubated for 10...More data for this Ligand-Target Pair
Affinity DataIC50: 932nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of ATP-induced ethidium iodide uptake preincubated for 10...More data for this Ligand-Target Pair
