Compile Data Set for Download or QSAR
Found 606 with Last Name = 'hillig' and Initial = 'rc'
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM50180955(CHEMBL3818617)copy SMILEScopy InChI
Affinity DataKi:  8nMAssay Description:Competitive inhibition of full length 6xHis-tagged SMYD2 (unknown origin) expressed in Escherichia coli using varying levels of Btn-Ahx-GSRAHSSHLKSKK...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN39S5PubMed
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM50180955(CHEMBL3818617)copy SMILEScopy InChI
Affinity DataKi:  28nMAssay Description:Uncompetitive inhibition of full length 6xHis-tagged SMYD2 (unknown origin) expressed in Escherichia coli using fixed levels of Btn-Ahx-GSRAHSSHLKSKK...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN39S5PubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))TBA
LigandPNGBDBM254887(US9493472, 10)copy SMILEScopy InChI
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of purified human plasma thrombin using Boc-Asp(OBzl)-Pro-Arg-AMC substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60SNDPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))TBA
LigandPNGBDBM50547821(CHEMBL4761137)copy SMILES
Affinity DataIC50: 0.270nMAssay Description:Inhibition of purified human plasma thrombin using Boc-Asp(OBzl)-Pro-Arg-AMC substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60SNDPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50520160(CHEMBL4515413 | US10894784, Example 01.03)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged FLT3 (564 to end residues) expressed in sf21 cells using biotin labelled Ahx-GGEEEEYFELVKKKK pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN7795PubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))TBA
LigandPNGBDBM254899(US9493472, 21)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Inhibition of purified human plasma thrombin using Boc-Asp(OBzl)-Pro-Arg-AMC substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60SNDPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))TBA
LigandPNGBDBM50547825(CHEMBL4749829)copy SMILES
Affinity DataIC50: 0.400nMAssay Description:Inhibition of purified human plasma thrombin using Boc-Asp(OBzl)-Pro-Arg-AMC substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60SNDPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))TBA
LigandPNGBDBM50547824(CHEMBL4754786)copy SMILES
Affinity DataIC50: 0.5nMAssay Description:Inhibition of purified human plasma thrombin using Boc-Asp(OBzl)-Pro-Arg-AMC substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60SNDPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))TBA
LigandPNGBDBM50547836(CHEMBL4763593)copy SMILES
Affinity DataIC50: 0.700nMAssay Description:Inhibition of purified human plasma thrombin using Boc-Asp(OBzl)-Pro-Arg-AMC substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60SNDPubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50520150(CHEMBL4566796)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of recombinant full length human N-terminal His-tagged TBK1 using biotin-labelled Ahx-GDEDFSSFAEPG peptide as substrate preincubated with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN7795PubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50520142(CHEMBL4435393)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant full length human N-terminal His-tagged TBK1 using biotin-labelled Ahx-GDEDFSSFAEPG peptide as substrate preincubated with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN7795PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50520159(CHEMBL4543618)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged FLT3 (564 to end residues) expressed in sf21 cells using biotin labelled Ahx-GGEEEEYFELVKKKK pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN7795PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50520175(CHEMBL4451595 | US10894784, Example 135.02)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged FLT3 (564 to end residues) expressed in sf21 cells using biotin labelled Ahx-GGEEEEYFELVKKKK pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN7795PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bayer HealthCare AG

Curated by ChEMBL
LigandPNGBDBM50134989(CHEMBL3746640)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of MEK1 in human HeLa-MaTu matched pair cells assessed as reduction in ERK phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M38NNPubMed
TargetP2X purinoceptor 4(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50506156(CHEMBL4471140)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048RWPubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50520151(CHEMBL4537673)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant full length human N-terminal His-tagged TBK1 using biotin-labelled Ahx-GDEDFSSFAEPG peptide as substrate preincubated with ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN7795PubMed
TargetP2X purinoceptor 4(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50506203(CHEMBL4452312)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048RWPubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50520159(CHEMBL4543618)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant full length human N-terminal His-tagged TBK1 using biotin-labelled Ahx-GDEDFSSFAEPG peptide as substrate preincubated with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN7795PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50520150(CHEMBL4566796)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant full length human C-terminal GST-tagged IKKepsilon expressed in baculovirus expression system using biotin-labelled Ahx-GDE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN7795PubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50520148(CHEMBL4538751 | US10894784, Example 30.03.01.A)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant full length human N-terminal His-tagged TBK1 using biotin-labelled Ahx-GDEDFSSFAEPG peptide as substrate preincubated with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN7795PubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))TBA
LigandPNGBDBM50547829(CHEMBL4776051)copy SMILES
Affinity DataIC50: 2nMAssay Description:Inhibition of purified human plasma thrombin using Boc-Asp(OBzl)-Pro-Arg-AMC substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60SNDPubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50520151(CHEMBL4537673)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant full length human C-terminal GST-tagged IKKepsilon expressed in baculovirus expression system using biotin-labelled Ahx-GDE...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN7795PubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50520165(CHEMBL4454902)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant full length human N-terminal His-tagged TBK1 using biotin-labelled Ahx-GDEDFSSFAEPG peptide as substrate preincubated with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN7795PubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50520157(CHEMBL4436188)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant full length human N-terminal His-tagged TBK1 using biotin-labelled Ahx-GDEDFSSFAEPG peptide as substrate preincubated with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN7795PubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))TBA
LigandPNGBDBM50547830(CHEMBL4796689)copy SMILES
Affinity DataIC50: 2.5nMAssay Description:Inhibition of purified human plasma thrombin using Boc-Asp(OBzl)-Pro-Arg-AMC substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60SNDPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))TBA
LigandPNGBDBM50547827(CHEMBL4786634)copy SMILES
Affinity DataIC50: 4nMAssay Description:Inhibition of purified human plasma thrombin using Boc-Asp(OBzl)-Pro-Arg-AMC substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60SNDPubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50520148(CHEMBL4538751 | US10894784, Example 30.03.01.A)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant full length human C-terminal GST-tagged IKKepsilon expressed in baculovirus expression system using biotin-labelled Ahx-GDE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN7795PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50520165(CHEMBL4454902)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant full length human C-terminal GST-tagged IKKepsilon expressed in baculovirus expression system using biotin-labelled Ahx-GDE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN7795PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50520157(CHEMBL4436188)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant full length human C-terminal GST-tagged IKKepsilon expressed in baculovirus expression system using biotin-labelled Ahx-GDE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN7795PubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))TBA
LigandPNGBDBM50547822(CHEMBL4787137)copy SMILES
Affinity DataIC50: 4.30nMAssay Description:Inhibition of purified human plasma thrombin using Boc-Asp(OBzl)-Pro-Arg-AMC substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60SNDPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))TBA
LigandPNGBDBM50547822(CHEMBL4787137)copy SMILES
Affinity DataIC50: 4.30nMAssay Description:Inhibition of purified human plasma thrombin using Boc-Asp(OBzl)-Pro-Arg-AMC substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60SNDPubMed
TargetP2X purinoceptor 4(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50506173(CHEMBL4589444)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048RWPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50520150(CHEMBL4566796)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged FLT3 (564 to end residues) expressed in sf21 cells using biotin labelled Ahx-GGEEEEYFELVKKKK pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN7795PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50520145(CHEMBL4459120)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant full length human His-tagged CDK9/CyclinT1 expressed in baculovirus expression system using biotin-labelled Ttds-YISPLKSPYK...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN7795PubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50520165(CHEMBL4454902)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant full length human N-terminal His-tagged TBK1 using biotin-labelled Ahx-GDEDFSSFAEPG peptide as substrate preincubated with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN7795PubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50520161(CHEMBL4468020 | US10894784, Example 39.01.02)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant full length human N-terminal His-tagged TBK1 using biotin-labelled Ahx-GDEDFSSFAEPG peptide as substrate preincubated with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN7795PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50520152(CHEMBL4594167 | US10894784, Example 150.02)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged FLT3 (564 to end residues) expressed in sf21 cells using biotin labelled Ahx-GGEEEEYFELVKKKK pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN7795PubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))TBA
LigandPNGBDBM50547828(CHEMBL4758225)copy SMILES
Affinity DataIC50: 6nMAssay Description:Inhibition of purified human plasma thrombin using Boc-Asp(OBzl)-Pro-Arg-AMC substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60SNDPubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50520142(CHEMBL4435393)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant full length human C-terminal GST-tagged IKKepsilon expressed in baculovirus expression system using biotin-labelled Ahx-GDE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN7795PubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50520157(CHEMBL4436188)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant full length human N-terminal His-tagged TBK1 using biotin-labelled Ahx-GDEDFSSFAEPG peptide as substrate preincubated with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN7795PubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50520150(CHEMBL4566796)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant full length human N-terminal His-tagged TBK1 using biotin-labelled Ahx-GDEDFSSFAEPG peptide as substrate preincubated with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN7795PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50520161(CHEMBL4468020 | US10894784, Example 39.01.02)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant full length human C-terminal GST-tagged IKKepsilon expressed in baculovirus expression system using biotin-labelled Ahx-GDE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN7795PubMed
TargetRibosomal protein S6 kinase alpha-6(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50520159(CHEMBL4543618)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant full length human His6-tagged RSK4 expressed in baculovirus infected sf21 cells using biotin labelled Ahx-KKLNRTLSFAEPG pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN7795PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bayer HealthCare AG

Curated by ChEMBL
LigandPNGBDBM104963(CHEMBL507361 | US11147816, PD0325901 | US11701360,...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of MEK1 (unknown origin) after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50506179(CHEMBL4579583)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048RWPubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM17051(BX-795 | BX-795, 3 | N-(3-{[5-iodo-4-({3-[(thiophe...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant full length human N-terminal His-tagged TBK1 using biotin-labelled Ahx-GDEDFSSFAEPG peptide as substrate preincubated with ...More data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(Homo sapiens (Human))TBA
LigandPNGBDBM50547832(CHEMBL4793547)copy SMILES
Affinity DataIC50: 8nMAssay Description:Inhibition of purified human plasma thrombin using Boc-Asp(OBzl)-Pro-Arg-AMC substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60SNDPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))TBA
LigandPNGBDBM50547820(CHEMBL4783934)copy SMILES
Affinity DataIC50: 8nMAssay Description:Inhibition of purified human plasma thrombin using Boc-Asp(OBzl)-Pro-Arg-AMC substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60SNDPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))TBA
LigandPNGBDBM50547833(CHEMBL4776950)copy SMILES
Affinity DataIC50: 8.70nMAssay Description:Inhibition of purified human plasma thrombin using Boc-Asp(OBzl)-Pro-Arg-AMC substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60SNDPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bayer HealthCare AG

Curated by ChEMBL
LigandPNGBDBM50134989(CHEMBL3746640)copy SMILEScopy InChI
Affinity DataIC50: 8.70nMAssay Description:Inhibition of MEK1 in human HeLa-MaTu-ADR matched pair cells assessed as reduction in ERK phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M38NNPubMed
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