Compile Data Set for Download or QSAR
Found 182 with Last Name = 'mease' and Initial = 'rc'
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM50246899((S)-2-(3-((S)-1-carboxy-5-(4-iodobenzamido)pentyl)...)copy SMILEScopy InChI
Affinity DataKi:  0.0100nMAssay Description:Inhibition of PSMA in human LNCaP cell extract using [3H]NAAG by radiometric assayMore data for this Ligand-Target Pair
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM50246899((S)-2-(3-((S)-1-carboxy-5-(4-iodobenzamido)pentyl)...)copy SMILEScopy InChI
Affinity DataKi:  0.0100nMAssay Description:Inhibition of PSMA in human LNCaP cell extract using [3H]NAAG by fluorescence-based assayMore data for this Ligand-Target Pair
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM456924(US10736974, Compound YC-I-27)copy SMILEScopy InChI
Affinity DataKi:  0.0100nMAssay Description:The PSMA inhibitory activity was determined using a modification of the fluorescence-based Amplex Red Glutamic Acid Assay. Briefly, lysates of LNCaP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29C71GJUS Patent
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM456928(US10736974, Compound XY-44)copy SMILEScopy InChI
Affinity DataKi:  0.0170nMAssay Description:The PSMA inhibitory activity was determined using a modification of the fluorescence-based Amplex Red Glutamic Acid Assay. Briefly, lysates of LNCaP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29C71GJUS Patent
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM456930(US10736974, Compound XY-59)copy SMILEScopy InChI
Affinity DataKi:  0.0200nMAssay Description:The PSMA inhibitory activity was determined using a modification of the fluorescence-based Amplex Red Glutamic Acid Assay. Briefly, lysates of LNCaP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29C71GJUS Patent
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM456923(US10736974, Compound DCIBC)copy SMILEScopy InChI
Affinity DataKi:  0.0300nMAssay Description:The PSMA inhibitory activity was determined using a modification of the fluorescence-based Amplex Red Glutamic Acid Assay. Briefly, lysates of LNCaP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29C71GJUS Patent
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM456931(US10736974, Compound XY-58)copy SMILEScopy InChI
Affinity DataKi:  0.0360nMAssay Description:The PSMA inhibitory activity was determined using a modification of the fluorescence-based Amplex Red Glutamic Acid Assay. Briefly, lysates of LNCaP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29C71GJUS Patent
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM456929(US10736974, Compound XY-45)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:The PSMA inhibitory activity was determined using a modification of the fluorescence-based Amplex Red Glutamic Acid Assay. Briefly, lysates of LNCaP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29C71GJUS Patent
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM50246934((S)-2-(3-((S)-1-carboxy-5-(4-fluorobenzamido)penty...)copy SMILEScopy InChI
Affinity DataKi:  0.194nMAssay Description:Inhibition of PSMA in human LNCaP cell extract using [3H]NAAG by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NKJPubMed
TargetProstate-specific antigen(Homo sapiens (Human))
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50298756((5S,8S,11S,14S,17R)-11-(4-aminobutyl)-5,8-bis(hydr...)copy SMILEScopy InChI
Affinity DataKi:  0.200nMAssay Description:Inhibition of prostate-specific antigen assessed as substrate hydrolysis by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43T49PubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM50246934((S)-2-(3-((S)-1-carboxy-5-(4-fluorobenzamido)penty...)copy SMILEScopy InChI
Affinity DataKi:  0.256nMAssay Description:Inhibition of PSMA in human LNCaP cell extract using [3H]NAAG by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NKJPubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM456920(US10736974, Entry 23)copy SMILEScopy InChI
Affinity DataKi:  0.260nMAssay Description:The PSMA inhibitory activity was determined using a modification of the fluorescence-based Amplex Red Glutamic Acid Assay. Briefly, lysates of LNCaP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29C71GJUS Patent
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM456925(US10736974, Compound YC-I-26)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:The PSMA inhibitory activity was determined using a modification of the fluorescence-based Amplex Red Glutamic Acid Assay. Briefly, lysates of LNCaP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29C71GJUS Patent
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM456914(US10736974, Compound XY-43 | US10736974, Entry 17)copy SMILEScopy InChI
Affinity DataKi:  0.320nMAssay Description:The PSMA inhibitory activity was determined using a modification of the fluorescence-based Amplex Red Glutamic Acid Assay. Briefly, lysates of LNCaP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29C71GJUS Patent
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM456914(US10736974, Compound XY-43 | US10736974, Entry 17)copy SMILEScopy InChI
Affinity DataKi:  0.320nMAssay Description:The PSMA inhibitory activity was determined using a modification of the fluorescence-based Amplex Red Glutamic Acid Assay. Briefly, lysates of LNCaP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29C71GJUS Patent
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM456927(US10736974, Compound C8)copy SMILEScopy InChI
Affinity DataKi:  0.350nMAssay Description:The PSMA inhibitory activity was determined using a modification of the fluorescence-based Amplex Red Glutamic Acid Assay. Briefly, lysates of LNCaP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29C71GJUS Patent
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM50246935((S)-2-(3-((S)-1-carboxy-5-(3-iodonicotinamido)pent...)copy SMILEScopy InChI
Affinity DataKi:  0.351nMAssay Description:Inhibition of PSMA in human LNCaP cell extract using [3H]NAAG by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NKJPubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM456921(US10736974, Entry 24)copy SMILEScopy InChI
Affinity DataKi:  0.400nMAssay Description:The PSMA inhibitory activity was determined using a modification of the fluorescence-based Amplex Red Glutamic Acid Assay. Briefly, lysates of LNCaP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29C71GJUS Patent
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM50246935((S)-2-(3-((S)-1-carboxy-5-(3-iodonicotinamido)pent...)copy SMILEScopy InChI
Affinity DataKi:  0.557nMAssay Description:Inhibition of PSMA in human LNCaP cell extract using [3H]NAAG by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NKJPubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM50304738(2-(3-((S)-1-carboxy-3-methylbutyl)ureido)pentanedi...)copy SMILEScopy InChI
Affinity DataKi:  0.75nMAssay Description:Inhibition of human cloned glutamate carboxypeptidase 2More data for this Ligand-Target Pair
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM456906(US10736974, Compound XY-26 | US10736974, Entry 9)copy SMILEScopy InChI
Affinity DataKi:  0.900nMAssay Description:The PSMA inhibitory activity was determined using a modification of the fluorescence-based Amplex Red Glutamic Acid Assay. Briefly, lysates of LNCaP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29C71GJUS Patent
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM456906(US10736974, Compound XY-26 | US10736974, Entry 9)copy SMILEScopy InChI
Affinity DataKi:  0.900nMAssay Description:The PSMA inhibitory activity was determined using a modification of the fluorescence-based Amplex Red Glutamic Acid Assay. Briefly, lysates of LNCaP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29C71GJUS Patent
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM456926(US10736974, Compound DCFPyL)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:The PSMA inhibitory activity was determined using a modification of the fluorescence-based Amplex Red Glutamic Acid Assay. Briefly, lysates of LNCaP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29C71GJUS Patent
TargetProstate-specific antigen(Homo sapiens (Human))
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50298754((5S,8S,11S,14S,17R)-11-(4-aminobutyl)-5,8-bis(hydr...)copy SMILEScopy InChI
Affinity DataKi:  2.5nMAssay Description:Inhibition of prostate-specific antigen assessed as substrate hydrolysis by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43T49PubMed
TargetProstate-specific antigen(Homo sapiens (Human))
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50298760(CHEMBL574766 | benzyl(2S,5S,8S,11S,14S)-8-(4-amino...)copy SMILEScopy InChI
Affinity DataKi:  3.60nMAssay Description:Inhibition of prostate-specific antigen assessed as substrate hydrolysis by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43T49PubMed
TargetProstate-specific antigen(Homo sapiens (Human))
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50298738(CHEMBL583783 | benzyl(2S,5S,8S,11S,14S)-8-(3-amino...)copy SMILEScopy InChI
Affinity DataKi:  3.90nMAssay Description:Inhibition of prostate-specific antigen assessed as substrate hydrolysis by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43T49PubMed
TargetProstate-specific antigen(Homo sapiens (Human))
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50298761(CHEMBL574788 | benzyl(2S,5S,8S,11S,14S)-8-(4-amino...)copy SMILEScopy InChI
Affinity DataKi:  4.40nMAssay Description:Inhibition of prostate-specific antigen assessed as substrate hydrolysis by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43T49PubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM456908(US10736974, Compound XY-28 | US10736974, Entry 11)copy SMILEScopy InChI
Affinity DataKi:  4.80nMAssay Description:The PSMA inhibitory activity was determined using a modification of the fluorescence-based Amplex Red Glutamic Acid Assay. Briefly, lysates of LNCaP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29C71GJUS Patent
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM456908(US10736974, Compound XY-28 | US10736974, Entry 11)copy SMILEScopy InChI
Affinity DataKi:  4.80nMAssay Description:The PSMA inhibitory activity was determined using a modification of the fluorescence-based Amplex Red Glutamic Acid Assay. Briefly, lysates of LNCaP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29C71GJUS Patent
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM50304731((S)-2-(3-((S)-1-Carboxy-2-(furan-2-yl)ethyl)ureido...)copy SMILEScopy InChI
Affinity DataKi:  5.30nMAssay Description:Inhibition of human cloned glutamate carboxypeptidase 2More data for this Ligand-Target Pair
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM50304722((S)-2-(3-((S)-1-Carboxybut-3-ynyl)ureido)-6-(4-iod...)copy SMILEScopy InChI
Affinity DataKi:  5.30nMAssay Description:Inhibition of human cloned glutamate carboxypeptidase 2More data for this Ligand-Target Pair
TargetProstate-specific antigen(Homo sapiens (Human))
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50298757((5S,8S,11S,14S,17R)-11-(4-aminobutyl)-5,8-bis(hydr...)copy SMILEScopy InChI
Affinity DataKi:  5.60nMAssay Description:Inhibition of prostate-specific antigen assessed as substrate hydrolysis by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43T49PubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM456900(US10736974, Entry 7)copy SMILEScopy InChI
Affinity DataKi:  6nMAssay Description:The PSMA inhibitory activity was determined using a modification of the fluorescence-based Amplex Red Glutamic Acid Assay. Briefly, lysates of LNCaP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29C71GJUS Patent
TargetProstate-specific antigen(Homo sapiens (Human))
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50298762(CHEMBL574924 | benzyl(2S,5S,8S,11S,14S)-8-(4-amino...)copy SMILEScopy InChI
Affinity DataKi:  6.5nMAssay Description:Inhibition of prostate-specific antigen assessed as substrate hydrolysis by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43T49PubMed
TargetProstate-specific antigen(Homo sapiens (Human))
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50298739(CHEMBL583784 | benzyl(2S,5S,8S,11S,14S)-14-formyl-...)copy SMILEScopy InChI
Affinity DataKi:  7.5nMAssay Description:Inhibition of prostate-specific antigen assessed as substrate hydrolysis by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43T49PubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM456911(US10736974, Entry 14)copy SMILEScopy InChI
Affinity DataKi:  8.30nMAssay Description:The PSMA inhibitory activity was determined using a modification of the fluorescence-based Amplex Red Glutamic Acid Assay. Briefly, lysates of LNCaP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29C71GJUS Patent
TargetProstate-specific antigen(Homo sapiens (Human))
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50298740(CHEMBL574324 | benzyl(2S,5S,8S,11S,14S)-14-formyl-...)copy SMILEScopy InChI
Affinity DataKi:  8.80nMAssay Description:Inhibition of prostate-specific antigen assessed as substrate hydrolysis by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43T49PubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM456912(US10736974, Entry 15)copy SMILEScopy InChI
Affinity DataKi:  9.30nMAssay Description:The PSMA inhibitory activity was determined using a modification of the fluorescence-based Amplex Red Glutamic Acid Assay. Briefly, lysates of LNCaP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29C71GJUS Patent
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM456917(US10736974, Entry 20)copy SMILEScopy InChI
Affinity DataKi:  9.70nMAssay Description:The PSMA inhibitory activity was determined using a modification of the fluorescence-based Amplex Red Glutamic Acid Assay. Briefly, lysates of LNCaP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29C71GJUS Patent
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM50304751((S)-2-(3-((S)-1-Carboxybut-3-enyl)ureido)-6-(4-iod...)copy SMILEScopy InChI
Affinity DataKi:  11nMAssay Description:Inhibition of human cloned glutamate carboxypeptidase 2More data for this Ligand-Target Pair
TargetProstate-specific antigen(Homo sapiens (Human))
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50298714(CHEMBL574925 | benzyl(2S,5S,8S,11S,14S)-8-(4-amino...)copy SMILEScopy InChI
Affinity DataKi:  11.9nMAssay Description:Inhibition of prostate-specific antigen assessed as substrate hydrolysis by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43T49PubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM456898(US10736974, Entry 5)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:The PSMA inhibitory activity was determined using a modification of the fluorescence-based Amplex Red Glutamic Acid Assay. Briefly, lysates of LNCaP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29C71GJUS Patent
TargetProstate-specific antigen(Homo sapiens (Human))
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50298715(CHEMBL575847 | benzyl(2S,5S,8S,11S,14S)-8-(4-amino...)copy SMILEScopy InChI
Affinity DataKi:  12.8nMAssay Description:Inhibition of prostate-specific antigen assessed as substrate hydrolysis by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43T49PubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM456913(US10736974, Compound XY-42 | US10736974, Entry 16)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:The PSMA inhibitory activity was determined using a modification of the fluorescence-based Amplex Red Glutamic Acid Assay. Briefly, lysates of LNCaP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29C71GJUS Patent
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM456913(US10736974, Compound XY-42 | US10736974, Entry 16)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:The PSMA inhibitory activity was determined using a modification of the fluorescence-based Amplex Red Glutamic Acid Assay. Briefly, lysates of LNCaP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29C71GJUS Patent
TargetProstate-specific antigen(Homo sapiens (Human))
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50298741(CHEMBL574931 | benzyl(2S,5S,8S,11S,14S)-7-cyclohex...)copy SMILEScopy InChI
Affinity DataKi:  13.1nMAssay Description:Inhibition of prostate-specific antigen assessed as substrate hydrolysis by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43T49PubMed
TargetProstate-specific antigen(Homo sapiens (Human))
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50298716(CHEMBL574792 | benzyl(2S,5S,8S,11S,14S)-8-(4-amino...)copy SMILEScopy InChI
Affinity DataKi:  13.1nMAssay Description:Inhibition of prostate-specific antigen assessed as substrate hydrolysis by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43T49PubMed
TargetProstate-specific antigen(Homo sapiens (Human))
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50298717(CHEMBL574845 | benzyl(2S,5S,8S,11S,14S)-8-(4-amino...)copy SMILEScopy InChI
Affinity DataKi:  13.7nMAssay Description:Inhibition of prostate-specific antigen assessed as substrate hydrolysis by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43T49PubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM456922(US10736974, Compound DCFBC)copy SMILEScopy InChI
Affinity DataKi:  14nMAssay Description:The PSMA inhibitory activity was determined using a modification of the fluorescence-based Amplex Red Glutamic Acid Assay. Briefly, lysates of LNCaP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29C71GJUS Patent
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM50304735((S)-2-(3-((S)-1-Carboxy-2-(thiazol-4-yl)ethyl)urei...)copy SMILEScopy InChI
Affinity DataKi:  16.1nMAssay Description:Inhibition of human cloned glutamate carboxypeptidase 2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN092XPubMed
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