Compile Data Set for Download or QSAR
Found 78 with Last Name = 'reynolds' and Initial = 'rc'
LigandPNGBDBM50396023(CHEMBL2169919)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]-SAM in recombinant human His-tagged DOT1L (1 to 416 residues) expressed in Escherichia coli BL21-Gold (DE3) cells incubated for ...More data for this Ligand-Target Pair
LigandPNGBDBM50396023(CHEMBL2169919)copy SMILEScopy InChI
Affinity DataIC50: 0.860nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using histone as substrate i...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Lactobacillus casei)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of Lactobacillus casei DHFRMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant DHFRMore data for this Ligand-Target Pair
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50009672(AdoHcy | CHEMBL418052 | S-(5'-adenosyl)-L-homocyst...)copy SMILEScopy InChI
Affinity DataIC50: 71nMAssay Description:Inhibition of recombinant human DNMT1 using poly(dl-dC) as substrate by hotspot assayMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 7(Homo sapiens (Human))TBA
LigandPNGBDBM50009672(AdoHcy | CHEMBL418052 | S-(5'-adenosyl)-L-homocyst...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant human PRMT7 using GST-GAR as substrate by hotspot assayMore data for this Ligand-Target Pair
LigandPNGBDBM50009672(AdoHcy | CHEMBL418052 | S-(5'-adenosyl)-L-homocyst...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant human PRMT8 using histone H4 as substrate by hotspot assayMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Mycobacterium avium)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM18069(5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of Mycobacterium avium DHFRMore data for this Ligand-Target Pair
TargetLeucine--tRNA ligase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Russian Academy of Science

Curated by ChEMBL
LigandPNGBDBM50241779(CHEMBL4082159)copy SMILEScopy InChI
Affinity DataIC50: 216nMAssay Description:Inhibition of Mycobacterium tuberculosis LeuRS expressed in Escherichia coli Rosetta (DE3) cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z480DPubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM18069(5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...)copy SMILEScopy InChI
Affinity DataIC50: 620nMAssay Description:Inhibition of Lactobacillus casei DHFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8MCNPubMed
LigandPNGBDBM50009672(AdoHcy | CHEMBL418052 | S-(5'-adenosyl)-L-homocyst...)copy SMILEScopy InChI
Affinity DataIC50: 760nMAssay Description:Inhibition of recombinant human PRMT3 using histone H4 as substrate by hotspot assayMore data for this Ligand-Target Pair
LigandPNGBDBM50551137(CHEMBL4765125)copy SMILES
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using histone as substrate i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))TBA
LigandPNGBDBM50009672(AdoHcy | CHEMBL418052 | S-(5'-adenosyl)-L-homocyst...)copy SMILEScopy InChI
Affinity DataIC50: 1.82E+3nMAssay Description:Inhibition of recombinant human G9a using histone H3 (1 to 21) as substrate by hotspot assayMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM18069(5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...)copy SMILEScopy InChI
Affinity DataIC50: 2.73E+3nMAssay Description:Inhibition of Toxoplasma gondii DHFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8MCNPubMed
LigandPNGBDBM50551132(CHEMBL4777038)copy SMILES
Affinity DataIC50: 1.09E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using histone as substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM18069(5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of Pneumocystis carinii DHFRMore data for this Ligand-Target Pair
TargetCell division protein FtsZ(Mycobacterium tuberculosis)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50359406(CHEMBL1926717)copy SMILEScopy InChI
Affinity DataIC50: 1.64E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0GZ1PubMed
TargetCell division protein FtsZ(Mycobacterium tuberculosis)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50359412(CHEMBL1926724)copy SMILEScopy InChI
Affinity DataIC50: 1.86E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0GZ1PubMed
LigandPNGBDBM50551136(CHEMBL4757320)copy SMILES
Affinity DataIC50: 1.95E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using histone as substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
TargetCell division protein FtsZ(Mycobacterium tuberculosis)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50359407(CHEMBL1926719)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0GZ1PubMed
LigandPNGBDBM50551135(CHEMBL4740900)copy SMILES
Affinity DataIC50: 2.24E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using histone as substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))TBA
LigandPNGBDBM50009672(AdoHcy | CHEMBL418052 | S-(5'-adenosyl)-L-homocyst...)copy SMILEScopy InChI
Affinity DataIC50: 2.26E+4nMAssay Description:Inhibition of recombinant human EZH2 using core histone as substrate by hotspot assayMore data for this Ligand-Target Pair
LigandPNGBDBM50551134(CHEMBL4761584)copy SMILES
Affinity DataIC50: 2.35E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using histone as substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
LigandPNGBDBM50551136(CHEMBL4757320)copy SMILES
Affinity DataIC50: 2.53E+4nMAssay Description:Inhibition of recombinant human PRMT3 using histone H4 as substrate by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
TargetCell division protein FtsZ(Mycobacterium tuberculosis)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50359400(CHEMBL1929425)copy SMILEScopy InChI
Affinity DataIC50: 2.68E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0GZ1PubMed
TargetCell division protein FtsZ(Mycobacterium tuberculosis)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50359410(CHEMBL1926722)copy SMILEScopy InChI
Affinity DataIC50: 2.73E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0GZ1PubMed
TargetCell division protein FtsZ(Mycobacterium tuberculosis)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50359413(CHEMBL1926725)copy SMILEScopy InChI
Affinity DataIC50: 2.95E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0GZ1PubMed
LigandPNGBDBM50551120(CHEMBL1889068)copy SMILES
Affinity DataIC50: 3.24E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using nucleosome as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
TargetCell division protein FtsZ(Mycobacterium tuberculosis)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50359411(CHEMBL1926723)copy SMILEScopy InChI
Affinity DataIC50: 3.41E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0GZ1PubMed
TargetCell division protein FtsZ(Mycobacterium tuberculosis)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50359398(CHEMBL110168)copy SMILEScopy InChI
Affinity DataIC50: 3.42E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0GZ1PubMed
TargetCell division protein FtsZ(Mycobacterium tuberculosis)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50359401(CHEMBL1929426)copy SMILEScopy InChI
Affinity DataIC50: 3.43E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0GZ1PubMed
TargetCell division protein FtsZ(Mycobacterium tuberculosis)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50359408(CHEMBL1926720)copy SMILEScopy InChI
Affinity DataIC50: 3.48E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0GZ1PubMed
LigandPNGBDBM50551130(CHEMBL4757791)copy SMILES
Affinity DataIC50: 3.69E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using histone as substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
TargetCell division protein FtsZ(Mycobacterium tuberculosis)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50359399(CHEMBL106808)copy SMILEScopy InChI
Affinity DataIC50: 3.81E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0GZ1PubMed
LigandPNGBDBM50551128(CHEMBL1700259)copy SMILES
Affinity DataIC50: 4.08E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using histone as substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
TargetCell division protein FtsZ(Mycobacterium tuberculosis)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50359402(CHEMBL1929427)copy SMILEScopy InChI
Affinity DataIC50: 4.57E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0GZ1PubMed
TargetCell division protein FtsZ(Mycobacterium tuberculosis)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50359414(CHEMBL1926726)copy SMILEScopy InChI
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0GZ1PubMed
TargetCell division protein FtsZ(Mycobacterium tuberculosis)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50359415(CHEMBL1926727)copy SMILEScopy InChI
Affinity DataIC50: 4.62E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0GZ1PubMed
TargetCell division protein FtsZ(Mycobacterium tuberculosis)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50359405(CHEMBL457349)copy SMILEScopy InChI
Affinity DataIC50: 5.20E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0GZ1PubMed
LigandPNGBDBM50551136(CHEMBL4757320)copy SMILES
Affinity DataIC50: 5.36E+4nMAssay Description:Inhibition of recombinant human PRMT8 using histone H4 as substrate by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
TargetCell division protein FtsZ(Mycobacterium tuberculosis)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50359409(CHEMBL1926721)copy SMILEScopy InChI
Affinity DataIC50: 5.46E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0GZ1PubMed
LigandPNGBDBM50551121(CHEMBL1701619)copy SMILES
Affinity DataIC50: 5.49E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using nucleosome as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
LigandPNGBDBM50551142(CHEMBL4755929)copy SMILES
Affinity DataIC50: 5.56E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using histone as substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
LigandPNGBDBM50551122(CHEMBL3183870)copy SMILES
Affinity DataIC50: 5.70E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using nucleosome as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))TBA
LigandPNGBDBM50551136(CHEMBL4757320)copy SMILES
Affinity DataIC50: 6.14E+4nMAssay Description:Inhibition of recombinant human G9a using histone H3 (1 to 21) as substrate by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
TargetProtein arginine N-methyltransferase 7(Homo sapiens (Human))TBA
LigandPNGBDBM50551136(CHEMBL4757320)copy SMILES
Affinity DataIC50: 6.15E+4nMAssay Description:Inhibition of recombinant human PRMT7 using GST-GAR as substrate by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
LigandPNGBDBM50551131(CHEMBL4787257)copy SMILES
Affinity DataIC50: 6.92E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using histone as substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
TargetProtein arginine N-methyltransferase 7(Homo sapiens (Human))TBA
LigandPNGBDBM50551131(CHEMBL4787257)copy SMILES
Affinity DataIC50: 6.94E+4nMAssay Description:Inhibition of recombinant human PRMT7 using GST-GAR as substrate by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
TargetHistone-lysine N-methyltransferase SETD7(Homo sapiens (Human))TBA
LigandPNGBDBM50551136(CHEMBL4757320)copy SMILES
Affinity DataIC50: 7.98E+4nMAssay Description:Inhibition of recombinant human SET7/9 using core histone as substrate by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
LigandPNGBDBM50551128(CHEMBL1700259)copy SMILES
Affinity DataIC50: 8.29E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using nucleosome as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
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