Compile Data Set for Download or QSAR
Found 54 with Last Name = 'damon' and Initial = 're'
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50291237(CHEMBL153492 | Sodium; (E)-(3R,5S)-7-[4-(4-fluoro-...)copy SMILEScopy InChI
Affinity DataIC50: 4.40nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB74NQ
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50291241(CHEMBL153021 | Sodium; (E)-(3R,5S)-7-[4-(4-fluoro-...)copy SMILEScopy InChI
Affinity DataIC50: 6.30nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB74NQ
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50288129((2-Phenyl-propyl)-{2-[4-((E)-styryl)-phenoxy]-ethy...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Compound was tested for inhibitory activity against squalene synthase using rat liver microsomal assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5DZZ
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50288124(Benzyl-{2-[4-((E)-styryl)-phenoxy]-ethyl}-amine | ...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Compound was tested for inhibitory activity against squalene synthase using rat liver microsomal assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5DZZ
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50291258(CHEMBL152366 | Sodium; (E)-(3R,5S)-7-[4-(4-fluoro-...)copy SMILEScopy InChI
Affinity DataIC50: 9.70nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB74NQ
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50288127(CHEMBL312125 | [2-(4-Benzyloxy-phenoxy)-ethyl]-(2-...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Compound was tested for inhibitory activity against squalene synthase using rat liver microsomal assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5DZZ
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50288123(CHEMBL82277 | [2-(4-Benzyloxy-phenoxy)-ethyl]-phen...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Compound was tested for inhibitory activity against squalene synthase using rat liver microsomal assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5DZZ
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50291255(CHEMBL358623 | Sodium; (E)-(3R,5S)-7-[4-(4-fluoro-...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB74NQ
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50291256(CHEMBL152129 | Sodium; (E)-(3R,5S)-7-[5-(4-chloro-...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB74NQ
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50291252(CHEMBL152551 | Sodium; (E)-(3R,5S)-7-[4-(4-fluoro-...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB74NQ
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50291239(CHEMBL151961 | Sodium; (E)-(3R,5S)-3,5-dihydroxy-7...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB74NQ
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50291243(CHEMBL152926 | Sodium; (E)-(3R,5S)-7-[4-(3-fluoro-...)copy SMILEScopy InChI
Affinity DataIC50: 49nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB74NQ
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50288128(Benzyl-(4-benzyloxy-benzyl)-amine | CHEMBL82015)copy SMILEScopy InChI
Affinity DataIC50: 55nMAssay Description:Compound was tested for inhibitory activity against squalene synthase using rat liver microsomal assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5DZZ
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50288125(Benzyl-[2-(4-benzyloxy-phenoxy)-ethyl]-amine | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Compound was tested for inhibitory activity against squalene synthase using rat liver microsomal assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5DZZ
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50291251(CHEMBL346856 | Sodium; (E)-(3R,5S)-3,5-dihydroxy-7...)copy SMILEScopy InChI
Affinity DataIC50: 94nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB74NQ
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50047461(Benzyl-((2E,6E)-3,7,11-trimethyl-dodeca-2,6,10-tri...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Compound was tested for inhibitory activity against squalene synthase using rat liver microsomal assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5DZZ
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50291254(CHEMBL357515 | Sodium; (R)-3-hydroxy-7-[(1S,2S,8S,...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB74NQ
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50291240(CHEMBL152032 | Sodium; (R)-7-[(1S,2S,6R,8S,8aR)-2,...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB74NQ
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50291259(CHEMBL152893 | Sodium; (E)-(3R,5S)-7-(4-cyclohexyl...)copy SMILEScopy InChI
Affinity DataIC50: 202nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB74NQ
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50291248(CHEMBL358245 | Sodium; (E)-(3R,5S)-7-[4-(4-fluoro-...)copy SMILEScopy InChI
Affinity DataIC50: 206nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB74NQ
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50291238(CHEMBL434313 | Sodium; (E)-(3R,5S)-7-[4-(2-fluoro-...)copy SMILEScopy InChI
Affinity DataIC50: 233nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB74NQ
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50291245(CHEMBL347277 | Sodium; (E)-(3R,5S)-7-[4-(4-fluoro-...)copy SMILEScopy InChI
Affinity DataIC50: 325nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB74NQ
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50291249(CHEMBL348225 | Sodium; (E)-(3R,5S)-7-(4-cyclopenty...)copy SMILEScopy InChI
Affinity DataIC50: 417nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB74NQ
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50004774((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-[2-(...)copy SMILEScopy InChI
Affinity DataIC50: 530nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB74NQ
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50291247(CHEMBL154868 | Sodium; (E)-(3R,5S)-7-[5-cyclopenty...)copy SMILEScopy InChI
Affinity DataIC50: 570nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB74NQ
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1,/2,/3,/4, mitochondrial(Homo sapiens (Human))
Novartis Institute for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50217006(CHEMBL440684)copy SMILEScopy InChI
Affinity DataIC50: 840nMAssay Description:In vitro inhibitory activity against pyruvate dehydrogenase kinase was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RN3B1QPubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50291260(CHEMBL154986 | Sodium; (E)-(3R,5S)-3,5-dihydroxy-7...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB74NQ
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50011036((S)-((1S,7S,8S,8aR)-8-(2-((2R,4R)-4-hydroxy-6-oxo-...)copy SMILEScopy InChI
Affinity DataIC50: 1.15E+3nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB74NQ
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50291253(CHEMBL152114 | Sodium; (E)-(3R,5S)-3,5-dihydroxy-7...)copy SMILEScopy InChI
Affinity DataIC50: 1.42E+3nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB74NQ
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50291246(CHEMBL346635 | Sodium; (E)-(3R,5S)-3,5-dihydroxy-7...)copy SMILEScopy InChI
Affinity DataIC50: 2.43E+3nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB74NQ
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50291244(CHEMBL150649 | Sodium; (E)-(3R,5S)-3,5-dihydroxy-7...)copy SMILEScopy InChI
Affinity DataIC50: 2.98E+3nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB74NQ
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1,/2,/3,/4, mitochondrial(Homo sapiens (Human))
Novartis Institute for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50217000(CHEMBL303716)copy SMILEScopy InChI
Affinity DataIC50: 5.40E+3nMAssay Description:In vitro inhibitory activity against pyruvate dehydrogenase kinase was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RN3B1QPubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1,/2,/3,/4, mitochondrial(Homo sapiens (Human))
Novartis Institute for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50217005(CHEMBL307896)copy SMILEScopy InChI
Affinity DataIC50: 5.80E+3nMAssay Description:In vitro inhibitory activity against pyruvate dehydrogenase kinase was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RN3B1QPubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1,/2,/3,/4, mitochondrial(Homo sapiens (Human))
Novartis Institute for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50217003(CHEMBL70688)copy SMILEScopy InChI
Affinity DataIC50: 6.70E+3nMAssay Description:In vitro inhibitory activity against pyruvate dehydrogenase kinase was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RN3B1QPubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1,/2,/3,/4, mitochondrial(Homo sapiens (Human))
Novartis Institute for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50217007(CHEMBL70488)copy SMILEScopy InChI
Affinity DataIC50: 9.50E+3nMAssay Description:In vitro inhibitory activity against pyruvate dehydrogenase kinase was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RN3B1QPubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50291242(CHEMBL347095 | Sodium; (E)-(3R,5S)-3,5-dihydroxy-7...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB74NQ
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50291257(CHEMBL152963 | Sodium; (E)-(3R,5S)-7-[4-(4-fluoro-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB74NQ
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50291250(CHEMBL358171 | Sodium; (E)-(3R,5S)-7-(4-biphenyl-4...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB74NQ
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1,/2,/3,/4, mitochondrial(Homo sapiens (Human))
Novartis Institute for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50442901(Abietic Acid | acs.jmedchem.1c00409_ST.770)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:In vitro inhibitory activity against pyruvate dehydrogenase kinase was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RN3B1QPubMed
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50288126(Benzyl-{2-[2-(4-benzyloxy-phenoxy)-ethoxy]-ethyl}-...)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+4nMAssay Description:Compound was tested for inhibitory activity against squalene synthase using rat liver microsomal assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5DZZ
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1,/2,/3,/4, mitochondrial(Homo sapiens (Human))
Novartis Institute for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50217004(CHEMBL70925)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+4nMAssay Description:In vitro inhibitory activity against pyruvate dehydrogenase kinase was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RN3B1QPubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1,/2,/3,/4, mitochondrial(Homo sapiens (Human))
Novartis Institute for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50217001(CHEMBL304098)copy SMILEScopy InChI
Affinity DataIC50: 5.10E+4nMAssay Description:In vitro inhibitory activity against pyruvate dehydrogenase kinase was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RN3B1QPubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1,/2,/3,/4, mitochondrial(Homo sapiens (Human))
Novartis Institute for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50217002(CHEMBL305511)copy SMILEScopy InChI
Affinity DataIC50: 5.60E+4nMAssay Description:In vitro inhibitory activity against pyruvate dehydrogenase kinase was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RN3B1QPubMed
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50288122(Benzyl-[2-(4-methoxy-phenoxy)-ethyl]-amine | CHEMB...)copy SMILEScopy InChI
Affinity DataIC50: 8.90E+4nMAssay Description:Compound was tested for inhibitory activity against squalene synthase using rat liver microsomal assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5DZZ
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1,/2,/3,/4, mitochondrial(Homo sapiens (Human))
Novartis Institute for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50080092((17beta)-17-hydroxyestr-4-en-3-one | 17beta-hydrox...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+5nMAssay Description:In vitro inhibitory activity against pyruvate dehydrogenase kinase was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RN3B1QPubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1,/2,/3,/4, mitochondrial(Homo sapiens (Human))
Novartis Institute for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM227588(DCA)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+6nMAssay Description:In vitro inhibitory activity against pyruvate dehydrogenase kinase was determinedMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Rattus norvegicus)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50175261(1-(5-chloro-2-methylphenyl)-3-isobutylthiourea | C...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:Activity against PPAR-alphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29023BWPubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50175260(1-(5-chloro-2-methylphenyl)-3-propylthiourea | CHE...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:Activity against PPAR-deltaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29023BWPubMed
TargetPeroxisome proliferator-activated receptor alpha(Rattus norvegicus)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50175260(1-(5-chloro-2-methylphenyl)-3-propylthiourea | CHE...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:Activity against PPAR-alphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29023BWPubMed
TargetPeroxisome proliferator-activated receptor alpha(Rattus norvegicus)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50175259((R)-N-(5-chloro-2-methylphenyl)-2-ethylpiperidine-...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:Activity against PPAR-alphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29023BWPubMed
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