Compile Data Set for Download or QSAR
Found 149 with Last Name = 'mayer' and Initial = 'rj'
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50004774((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-[2-(...)copy SMILEScopy InChI
Affinity DataKi:  0.600nMAssay Description:Inhibition of human HMGCoA reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28052MW
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50279858((3R,5R)-7-(2-Benzyloxy-4,6-dichloro-phenyl)-3,5-di...)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:The inhibitory activity of the compound against purified recombinant human HMG-CoA reductase was evaluatedMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21836DP
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50279859((S)-4-{[2-(2-Benzyloxy-4,6-dichloro-phenyl)-ethyl]...)copy SMILEScopy InChI
Affinity DataKi:  16nMAssay Description:The inhibitory activity of the compound against purified recombinant human HMG-CoA reductase was evaluatedMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21836DP
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50004774((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-[2-(...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human HMGCoA reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28052MW
TargetInterstitial collagenase(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063918((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-1-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Inhibitory activity of the compound towards human recombinant fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063918((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-1-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibitory activity towards human recombinant fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZK5FT6PubMed
TargetInterstitial collagenase(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069610((2R,3S)-N*1*-Hydroxy-2-(4-hydroxy-phenylsulfanylme...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibitory activity of the compound towards human recombinant fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069616((2R,3S)-N*1*-Hydroxy-2-{2-[(E)-hydroxyimino]-2-phe...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069604(CHEMBL118054 | [(2S,3R)-3-((S)-1-Carbamoyl-2-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069601((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-1-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082226((2R,3S)-N*4*-((S)-1-Carbamoyl-2,2-dimethyl-propyl)...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against IgE receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6C37PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082225((2R,3S)-N*4*-((S)-1-Carbamoyl-2,2-dimethyl-propyl)...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against IgE receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6C37PubMed
TargetInterstitial collagenase(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069583((R)-N*1*-((S)-1-Benzylcarbamoyl-2-phenyl-ethyl)-2-...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibitory activity towards human recombinant fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZK5FT6PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082218((2R,3S)-2-Benzo[b]thiophen-2-ylmethyl-N*1*-((S)-1-...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against IgE receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6C37PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069620((2R,3S)-N*1*-((S)-1-Carbamoyl-2-phenyl-ethyl)-N*4*...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069608((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-1-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibitory activity of the compound towards human recombinant fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069612(2-[(2S,3R)-2-Hydroxycarbamoyl-5-methyl-3-((S)-1-me...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibitory activity of the compound towards human recombinant fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069606((2R,3S)-2-Benzylsulfanylmethyl-N*1*-hydroxy-3-isob...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibitory activity of the compound towards human recombinant fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069606((2R,3S)-2-Benzylsulfanylmethyl-N*1*-hydroxy-3-isob...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 30-1...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069597((2R,3S)-N*1*-((S)-1-Carbamoyl-2-phenyl-ethyl)-N*4*...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069582((R)-N*1*-((S)-1-Benzylcarbamoyl-2-phenyl-ethyl)-N*...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibitory activity towards human recombinant fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZK5FT6PubMed
TargetInterstitial collagenase(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069582((R)-N*1*-((S)-1-Benzylcarbamoyl-2-phenyl-ethyl)-N*...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibitory activity of the compound towards human recombinant fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069603((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-1-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibitory activity of the compound towards human recombinant fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069598((2R,3S)-N*4*-((S)-1-Carbamoyl-2-phenyl-ethyl)-2-{2...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibitory activity of the compound towards human recombinant fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069610((2R,3S)-N*1*-Hydroxy-2-(4-hydroxy-phenylsulfanylme...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 40-8...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069608((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-1-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 40-8...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069597((2R,3S)-N*1*-((S)-1-Carbamoyl-2-phenyl-ethyl)-N*4*...)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibitory activity of the compound towards human recombinant fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069619(4-[(2S,3R)-2-Hydroxycarbamoyl-5-methyl-3-((S)-1-me...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 50-1...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069598((2R,3S)-N*4*-((S)-1-Carbamoyl-2-phenyl-ethyl)-2-{2...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031795((N-(2-HYDROXAMATEMETHYLENE-4-METHYL-PENTOYL)PHENYL...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibitory activity of the compound towards human recombinant fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50403719(CHEMBL2111687)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibitory activity against IgE receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6C37PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50403718(CHEMBL2112477)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibitory activity against IgE receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6C37PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082221((2R,3S)-N*1*-((S)-1-Carbamoyl-2,2-dimethyl-propyl)...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibitory activity against IgE receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6C37PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069621((2R,3S)-N*4*-Hydroxy-2-isobutyl-3-{2-[(E)-methoxyi...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082214((2R,3S)-2-Benzofuran-2-ylmethyl-3,N*4*-dihydroxy-N...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against matrix metalloprotease (MMP-1)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6C37PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063918((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-1-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZK5FT6PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069600((2R,3S)-N*4*-((S)-1-Carbamoyl-2-phenyl-ethyl)-N*1*...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069603((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-1-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 100-...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069605((2R,3S)-2-Benzyl-N*1*-((S)-1-carbamoyl-2-phenyl-et...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 100-...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069607((2R,3S)-2-Carbamoylmethylsulfanylmethyl-N*4*-((S)-...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 100-...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063918((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-1-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069612(2-[(2S,3R)-2-Hydroxycarbamoyl-5-methyl-3-((S)-1-me...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082214((2R,3S)-2-Benzofuran-2-ylmethyl-3,N*4*-dihydroxy-N...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against IgE receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6C37PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082216((2R,3S)-N*1*-((S)-1-Carbamoyl-2-phenyl-ethyl)-2-(7...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against IgE receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6C37PubMed
TargetInterstitial collagenase(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069617((2R,3S)-N*4*-((S)-1-Carbamoyl-2-phenyl-ethyl)-2-cy...)copy SMILEScopy InChI
Affinity DataIC50: 106nMAssay Description:Inhibitory activity of the compound towards human recombinant fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069613((2R,3S)-N*1*-((S)-1-Carbamoyl-2-phenyl-ethyl)-N*4*...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069609((2R,3S)-2-{2-Biphenyl-4-yl-2-[(E)-hydroxyimino]-et...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069618((2R,3S)-2-Benzyl-N*1*-((S)-1-carbamoyl-2-phenyl-et...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082218((2R,3S)-2-Benzo[b]thiophen-2-ylmethyl-N*1*-((S)-1-...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibitory activity against matrix metalloproteinase(MMP-1)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6C37PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069595((2R,3S)-2-Benzyl-N*1*-((S)-1-carbamoyl-2-phenyl-et...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q3WPubMed
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