Compile Data Set for Download or QSAR
Found 165 with Last Name = 'mourey' and Initial = 'rj'
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297122((R)-10-Methyl-9,10,11,12-tetrahydro-7-thia-4,9,12-...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SM7PubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297122((R)-10-Methyl-9,10,11,12-tetrahydro-7-thia-4,9,12-...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SM7PubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297120((R)-9-Methyl-8,9,10,11-tetrahydro-3-oxa-6-thia-8,1...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SM7PubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297124((R)-3-Chloro-10-methyl-9,10,11,12-tetrahydro-7-thi...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SM7PubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297121((R)-9-Methyl-1,2,8,9,10,11-hexahydro-3-oxa-6-thia-...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SM7PubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297119((R)-10-Methyl-3-(4-methyl-pyridin-3-yl)-9,10,11,12...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SM7PubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297113((R)-10-Methyl-3-pyridin-3-yl-9,10,11,12-tetrahydro...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SM7PubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297151((3R)-3-(aminomethyl)-9-methoxy-1,2,3,4-tetrahydro-...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM30204(Pyrrolopyridine, 35)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:The phosphorylation of HSP27 peptide by MAPKAPK2 was measured using an anion exchange resin capture assay method. The reaction was carried out in rea...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2794313PubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM30202(Pyrrolopyridine, 33)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:The phosphorylation of HSP27 peptide by MAPKAPK2 was measured using an anion exchange resin capture assay method. The reaction was carried out in rea...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2794313PubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM30185(CHEMBL226403 | Pyrrolopyridine, 16)copy SMILEScopy InChI
Affinity DataIC50: 8.5nMpH: 7.5 T: 2°CAssay Description:The phosphorylation of HSP27 peptide by MAPKAPK2 was measured using an anion exchange resin capture assay method. The reaction was carried out in rea...More data for this Ligand-Target Pair
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297125((R)-10-Methyl-3-phenyl-9,10,11,12-tetrahydro-7-thi...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SM7PubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297146((R)-3-Isobutoxy-7-methyl-5,6,7,8-tetrahydro-10-thi...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K795KPubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50119298((R)-3-Methoxy-7-methyl-5,6,7,8-tetrahydro-10-thia-...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SM7PubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50119298((R)-3-Methoxy-7-methyl-5,6,7,8-tetrahydro-10-thia-...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K795KPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Pfizer

LigandPNGBDBM19440(1-[3-(4-chlorophenyl)-4-(pyridin-4-yl)-1H-pyrazol-...)copy SMILEScopy InChI
Affinity DataIC50: 12nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed in reaction buffer containing substrate, enzyme, and inhibitor in the presence of 50 uM ATP/[gamma-33P] ATP. 33P incorpor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3HD5PubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297149((S)-7-Hydroxymethyl-3-methoxy-5,6,7,8-tetrahydro-1...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K795KPubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297117((R)-3-(2-Fluoro-phenyl)-10-methyl-9,10,11,12-tetra...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SM7PubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297126((R)-10-Methyl-3-pyridin-4-yl-9,10,11,12-tetrahydro...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SM7PubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM30201(Pyrrolopyridine, 32)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:The phosphorylation of HSP27 peptide by MAPKAPK2 was measured using an anion exchange resin capture assay method. The reaction was carried out in rea...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2794313PubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297120((R)-9-Methyl-8,9,10,11-tetrahydro-3-oxa-6-thia-8,1...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SM7PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Pfizer

LigandPNGBDBM19439(1-[3-(4-chlorophenyl)-4-(pyridin-4-yl)-1H-pyrazol-...)copy SMILEScopy InChI
Affinity DataIC50: 16nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed in reaction buffer containing substrate, enzyme, and inhibitor in the presence of 50 uM ATP/[gamma-33P] ATP. 33P incorpor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3HD5PubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM30203(Pyrrolopyridine, 34)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:The phosphorylation of HSP27 peptide by MAPKAPK2 was measured using an anion exchange resin capture assay method. The reaction was carried out in rea...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2794313PubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297115((R)-3-(2-Methoxy-phenyl)-10-methyl-9,10,11,12-tetr...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SM7PubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM30188(Pyrrolopyridine, 19)copy SMILEScopy InChI
Affinity DataIC50: 21nMpH: 7.5 T: 2°CAssay Description:The phosphorylation of HSP27 peptide by MAPKAPK2 was measured using an anion exchange resin capture assay method. The reaction was carried out in rea...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2794313PubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM30200(Pyrrolopyridine, 31)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:The phosphorylation of HSP27 peptide by MAPKAPK2 was measured using an anion exchange resin capture assay method. The reaction was carried out in rea...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2794313PubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297114((R)-10-Methyl-3-pyrimidin-5-yl-9,10,11,12-tetrahyd...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SM7PubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM30187(Pyrrolopyridine, 18)copy SMILEScopy InChI
Affinity DataIC50: 25nMpH: 7.5 T: 2°CAssay Description:The phosphorylation of HSP27 peptide by MAPKAPK2 was measured using an anion exchange resin capture assay method. The reaction was carried out in rea...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2794313PubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297149((S)-7-Hydroxymethyl-3-methoxy-5,6,7,8-tetrahydro-1...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K795KPubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297124((R)-3-Chloro-10-methyl-9,10,11,12-tetrahydro-7-thi...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SM7PubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297142((R)-3-Hydroxy-7-methyl-5,6,7,8-tetrahydro-10-thia-...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K795KPubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297121((R)-9-Methyl-1,2,8,9,10,11-hexahydro-3-oxa-6-thia-...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SM7PubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297118((R)-10-Methyl-3-o-tolyl-9,10,11,12-tetrahydro-7-th...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SM7PubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM30184(Pyrrolopyridine, 15)copy SMILEScopy InChI
Affinity DataIC50: 30nMpH: 7.5 T: 2°CAssay Description:The phosphorylation of HSP27 peptide by MAPKAPK2 was measured using an anion exchange resin capture assay method. The reaction was carried out in rea...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2794313PubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297146((R)-3-Isobutoxy-7-methyl-5,6,7,8-tetrahydro-10-thi...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K795KPubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM30193(Pyrrolopyridine, 24)copy SMILEScopy InChI
Affinity DataIC50: 30nMpH: 7.5 T: 2°CAssay Description:The phosphorylation of HSP27 peptide by MAPKAPK2 was measured using an anion exchange resin capture assay method. The reaction was carried out in rea...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2794313PubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM30191(Pyrrolopyridine, 22)copy SMILEScopy InChI
Affinity DataIC50: 32nMpH: 7.5 T: 2°CAssay Description:The phosphorylation of HSP27 peptide by MAPKAPK2 was measured using an anion exchange resin capture assay method. The reaction was carried out in rea...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2794313PubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM30190(Pyrrolopyridine, 21)copy SMILEScopy InChI
Affinity DataIC50: 37nMpH: 7.5 T: 2°CAssay Description:The phosphorylation of HSP27 peptide by MAPKAPK2 was measured using an anion exchange resin capture assay method. The reaction was carried out in rea...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2794313PubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50119298((R)-3-Methoxy-7-methyl-5,6,7,8-tetrahydro-10-thia-...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SM7PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Pfizer

LigandPNGBDBM19435(1-[3-(4-chlorophenyl)-4-(pyridin-4-yl)-1H-pyrazol-...)copy SMILEScopy InChI
Affinity DataIC50: 40nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed in reaction buffer containing substrate, enzyme, and inhibitor in the presence of 50 uM ATP/[gamma-33P] ATP. 33P incorpor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3HD5PubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50119298((R)-3-Methoxy-7-methyl-5,6,7,8-tetrahydro-10-thia-...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K795KPubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297116((R)-3-(3-Methoxy-phenyl)-10-methyl-9,10,11,12-tetr...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SM7PubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM30199(Pyrrolopyridine, 30)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:The phosphorylation of HSP27 peptide by MAPKAPK2 was measured using an anion exchange resin capture assay method. The reaction was carried out in rea...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2794313PubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM30205(Pyrrolopyridine, 36)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:The phosphorylation of HSP27 peptide by MAPKAPK2 was measured using an anion exchange resin capture assay method. The reaction was carried out in rea...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2794313PubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM30180(Pyrrolopyridine, 11)copy SMILEScopy InChI
Affinity DataIC50: 48nMpH: 7.5 T: 2°CAssay Description:The phosphorylation of HSP27 peptide by MAPKAPK2 was measured using an anion exchange resin capture assay method. The reaction was carried out in rea...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2794313PubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM30194(Pyrrolopyridine, 25)copy SMILEScopy InChI
Affinity DataIC50: 50nMpH: 7.5 T: 2°CAssay Description:The phosphorylation of HSP27 peptide by MAPKAPK2 was measured using an anion exchange resin capture assay method. The reaction was carried out in rea...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2794313PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Pfizer

LigandPNGBDBM19430(1-[3-(4-chlorophenyl)-4-(pyridin-4-yl)-1H-pyrazol-...)copy SMILEScopy InChI
Affinity DataIC50: 50nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed in reaction buffer containing substrate, enzyme, and inhibitor in the presence of 50 uM ATP/[gamma-33P] ATP. 33P incorpor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3HD5PubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297122((R)-10-Methyl-9,10,11,12-tetrahydro-7-thia-4,9,12-...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of MK2 in human U937 cells assessed as blockade of LPS-stimulated TNFalpha productionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SM7PubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM30197(Pyrrolopyridine, 28)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:The phosphorylation of HSP27 peptide by MAPKAPK2 was measured using an anion exchange resin capture assay method. The reaction was carried out in rea...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2794313PubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297144((R)-3-Cyclopropylmethoxy-7-methyl-5,6,7,8-tetrahyd...)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K795KPubMed
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