Compile Data Set for Download or QSAR
Found 603 with Last Name = 'skene' and Initial = 'rj'
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50394247(CHEMBL2159192)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34ZKRPubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50394245(CHEMBL2159190)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34ZKRPubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50335797(2-[2-(3-(R)-Aminopyrimidin-1-yl)-5-bromo-6-oxo-6H-...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X5828PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50322823((S)-N-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahy...)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM16281(2-({2-[(3R)-3-aminopiperidin-1-yl]-7-fluoro-6-meth...)copy SMILEScopy InChI
Affinity DataIC50: 4nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM78C5PubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50335784(2-[6-(3-Aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM16274(2-({2-[(3R)-3-aminopiperidin-1-yl]-6-fluoro-4-oxo-...)copy SMILEScopy InChI
Affinity DataIC50: 4nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM78C5PubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50335792(2-{6-[3(R)-Aminopiperidin-1-yl]-2,4-dioxo-3,4-dihy...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X5828PubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50335768(2-[2-(3-(R)-Aminopiperidin-1-yl)-5-methoxy-6-oxo-6...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X5828PubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50394248(CHEMBL2159193)copy SMILEScopy InChI
Affinity DataIC50: 4.60nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34ZKRPubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50394243(CHEMBL2159188)copy SMILEScopy InChI
Affinity DataIC50: 4.80nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34ZKRPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Takeda San Diego

Curated by ChEMBL
LigandPNGBDBM50317946(CHEMBL1095451 | N-hydroxy-3-(3-(5-methyl-1-pheneth...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant HDAC2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2514058PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Takeda San Diego

Curated by ChEMBL
LigandPNGBDBM50317947((R)-N-hydroxy-3-(3-(5-methyl-1-(1-methylpiperidin-...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant HDAC2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2514058PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Takeda San Diego

Curated by ChEMBL
LigandPNGBDBM50317949((R)-N-hydroxy-3-(3-(1-(1-isopropylpiperidin-3-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant HDAC2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2514058PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Takeda San Diego

Curated by ChEMBL
LigandPNGBDBM50317960(3-(3-(5-benzyl-4-methyl-1-phenethyl-1H-imidazol-2-...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant HDAC2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2514058PubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM16273(2-({2-[(3R)-3-aminopiperidin-1-yl]-5-fluoro-4-oxo-...)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM78C5PubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50335774(2-((2-(3-(R)-Aminopiperidin-1-yl)-5-bromo-6-oxopyr...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM16279(2-({2-[(3R)-3-aminopiperidin-1-yl]-6-bromo-4-oxo-3...)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM78C5PubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50335756(2-[2-(3-(R)-Aminopiperidin-1-yl)-5-prop-1-ynyl-6-o...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X5828PubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50335757(2-[2-(3-(R)-Aminopiperidin-1-yl)-5-ethynyl-6-oxo-6...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X5828PubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50335759(2-[2-(3-(R)-Aminopiperidin-1-yl)-6-oxo-5-(1H-pyrro...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X5828PubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM16275(2-({2-[(3R)-3-aminopiperidin-1-yl]-6-chloro-4-oxo-...)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM78C5PubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50335777(2-[2-(3-(R)-Aminopiperidin-1-yl)-5-fluoro-6-oxo-6H...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X5828PubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50335771(2-[2-(3-(R)-Aminopiperidin-1-yl)-5-iodo-6-oxo-6H-p...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X5828PubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50335793(2-((2-(3-(R)-Aminopiperidin-1-yl)-5-bromo-6-oxopyr...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X5828PubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50335798(2-[2-(3-(R)-Aminopiperidin-1-yl)-6-oxo-5-((E)-2-py...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X5828PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Takeda San Diego

Curated by ChEMBL
LigandPNGBDBM50317954((R)-N-hydroxy-3-(3-(1-(1-isopropylpiperidin-3-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 6.30nMAssay Description:Inhibition of human recombinant HDAC2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2514058PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Takeda San Diego

Curated by ChEMBL
LigandPNGBDBM50317948(6-(1-((R)-1-ethylpiperidin-3-yl)-5-methyl-4-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 6.30nMAssay Description:Inhibition of human recombinant HDAC2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2514058PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Takeda San Diego

Curated by ChEMBL
LigandPNGBDBM50317957((R)-3-(3-(4-benzyl-5-methyl-1-(1-methylpiperidin-3...)copy SMILEScopy InChI
Affinity DataIC50: 6.30nMAssay Description:Inhibition of human recombinant HDAC2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2514058PubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50394246(CHEMBL2159191)copy SMILEScopy InChI
Affinity DataIC50: 6.90nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34ZKRPubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50335775(2-[2-(3-(R)-Aminopiperidin-1-yl)-5-chloro-6-oxo-6H...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X5828PubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM16285(2-({6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2,4-di...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50394242(CHEMBL2159187)copy SMILEScopy InChI
Affinity DataIC50: 7.60nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34ZKRPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Takeda San Diego

Curated by ChEMBL
LigandPNGBDBM50317962(3-(3-(4,5-dimethyl-1-phenethyl-1H-imidazol-2-yl)ph...)copy SMILEScopy InChI
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human recombinant HDAC2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2514058PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Takeda San Diego

Curated by ChEMBL
LigandPNGBDBM50317956(3-(3-(4-benzyl-5-methyl-1-phenethyl-1H-imidazol-2-...)copy SMILEScopy InChI
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human recombinant HDAC2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2514058PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Takeda San Diego

Curated by ChEMBL
LigandPNGBDBM50317951(CHEMBL1096433 | N-hydroxy-3-(3-(4-methyl-1-pheneth...)copy SMILEScopy InChI
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human recombinant HDAC2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2514058PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Takeda San Diego

Curated by ChEMBL
LigandPNGBDBM50317965(CHEMBL1099096 | N-hydroxy-3-(3-(1-phenethyl-1H-ben...)copy SMILEScopy InChI
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human recombinant HDAC2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2514058PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Takeda San Diego

Curated by ChEMBL
LigandPNGBDBM50317953((R)-3-(3-(1-(1-ethylpiperidin-3-yl)-4-methyl-5-phe...)copy SMILEScopy InChI
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human recombinant HDAC2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2514058PubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))TBA
LigandPNGBDBM50605601(CHEMBL5184138)copy SMILES
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7TK7PubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM16280(2-({2-[(3R)-3-aminopiperidin-1-yl]-6-methoxy-4-oxo...)copy SMILEScopy InChI
Affinity DataIC50: 8nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM78C5PubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50335753(2-[2-(3-(R)-Aminopiperidin-1-yl)-6-oxo-5-vinyl-6H-...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X5828PubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50375237(CHEMBL272114)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50335787(6-[3-(R)-Aminopiperidin-1-yl]-1-(2-bromo-5-fluorob...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X5828PubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50335794(2-((2-(3-(R)-Aminopiperidin-1-yl)-5-chloro-6-oxopy...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X5828PubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50335795(2-((2-(3-(R)-Aminopiperidin-1-yl)-5-fluoro-6-oxopy...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X5828PubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50335773(2[2-(3-(R)-Aminopiperidin-1-yl)-5-bromo-4-methyl-6...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X5828PubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))TBA
LigandPNGBDBM50605597(CHEMBL5204161)copy SMILES
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7TK7PubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))TBA
LigandPNGBDBM50605598(CHEMBL5188193)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7TK7PubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50394249(CHEMBL2159194)copy SMILEScopy InChI
Affinity DataIC50: 9.90nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34ZKRPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Takeda San Diego

Curated by ChEMBL
LigandPNGBDBM50317983(CHEMBL1099057 | N-hydroxy-3-(3-(1-(2-(piperidin-1-...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant HDAC2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2514058PubMed
Displayed 1 to 50 (of 603 total ) | Next | Last >>
Jump to: