Found 249 with Last Name = 'narla' and Initial = 'rk' 
Affinity DataIC50: 0.900nMAssay Description:Inhibition of full length TTK (unknown origin) using MBP-derived peptide as substrate preincubated for 1 hr in dark followed by substrate addition an...More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 1nMAssay Description:Displacement of kinase tracer 236 from TTK (unknown origin) by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Displacement of kinase tracer 236 from TTK (unknown origin) by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Displacement of kinase tracer 236 from TTK (unknown origin) by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Displacement of kinase tracer 236 from TTK (unknown origin) by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Displacement of kinase tracer 236 from TTK (unknown origin) by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Celgene Corporation
Curated by ChEMBL
Celgene Corporation
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant mTOR (unknown origin) using GST-p70S6 as substrate after 60 mins by TR-FRET analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Displacement of kinase tracer 236 from TTK (unknown origin) by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Displacement of kinase tracer 236 from TTK (unknown origin) by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Displacement of kinase tracer 236 from TTK (unknown origin) by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Displacement of kinase tracer 236 from TTK (unknown origin) by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Displacement of kinase tracer 236 from TTK (unknown origin) by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Celgene Corporation
Curated by ChEMBL
Celgene Corporation
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of mTOR (unknown origin) by HTR-FRET substrate phosphorylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Displacement of kinase tracer 236 from TTK (unknown origin) by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Displacement of kinase tracer 236 from TTK (unknown origin) by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Celgene Corporation
Curated by ChEMBL
Celgene Corporation
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of mTOR (unknown origin) by HTR-FRET substrate phosphorylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of mTORC1 in human PC3 cells assessed as inhibition of p70S6K phosphorylation after 1 hrMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Celgene Corporation
Curated by ChEMBL
Celgene Corporation
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of mTOR (unknown origin) by HTR-FRET substrate phosphorylation assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Celgene Corporation
Curated by ChEMBL
Celgene Corporation
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of mTOR (unknown origin) by HTR-FRET substrate phosphorylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human full length recombinant GST-tagged TTK expressed in baculovirus by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.30nMAssay Description:Displacement of kinase tracer 236 from TTK (unknown origin) by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.60nMAssay Description:Displacement of kinase tracer 236 from TTK (unknown origin) by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Celgene Corporation
Curated by ChEMBL
Celgene Corporation
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of human GST-tagged CLK2 expressed in baculovirus by Z'-LYTE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of mTORC1 in human PC3 cells assessed as inhibition of p70S6K phosphorylation after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Displacement of kinase tracer 236 from TTK (unknown origin) by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.5nMAssay Description:Displacement of kinase tracer 236 from TTK (unknown origin) by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of mTORC1 in human PC3 cells assessed as inhibition of p70S6K phosphorylation after 1 hrMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Celgene Corporation
Curated by ChEMBL
Celgene Corporation
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of mTOR (unknown origin) by HTR-FRET substrate phosphorylation assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Celgene Corporation
Curated by ChEMBL
Celgene Corporation
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant mTOR (unknown origin) using GST-p70S6 as substrate after 60 mins by TR-FRET analysisMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Celgene Corporation
Curated by ChEMBL
Celgene Corporation
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of mTOR (unknown origin) by HTR-FRET substrate phosphorylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Displacement of kinase tracer 236 from TTK (unknown origin) by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Celgene Corporation
Curated by ChEMBL
Celgene Corporation
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of mTOR (unknown origin) by HTR-FRET substrate phosphorylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of mTORC1 in human PC3 cells assessed as inhibition of p70S6K phosphorylation after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of mTORC1 in human PC3 cells assessed as inhibition of p70S6K phosphorylation after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of mTORC1 in human PC3 cells assessed as inhibition of p70S6K phosphorylation after 1 hrMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Celgene Corporation
Curated by ChEMBL
Celgene Corporation
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of mTOR (unknown origin) by HTR-FRET substrate phosphorylation assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Celgene Corporation
Curated by ChEMBL
Celgene Corporation
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of mTOR (unknown origin) by HTR-FRET substrate phosphorylation assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Celgene Corporation
Curated by ChEMBL
Celgene Corporation
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of mTOR (unknown origin) by HTR-FRET substrate phosphorylation assayMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Homo sapiens (Human))
Celgene Corporation
Curated by ChEMBL
Celgene Corporation
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of adrenergic receptor alpha1 (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Celgene Corporation
Curated by ChEMBL
Celgene Corporation
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of mTOR (unknown origin) by HTR-FRET substrate phosphorylation assayMore data for this Ligand-Target Pair
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
Celgene Corporation
Curated by ChEMBL
Celgene Corporation
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of human DNA PKMore data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Celgene Corporation
Curated by ChEMBL
Celgene Corporation
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of CLK2 in human HCT116 cell lysate after 1 hr by LC-MS/MS analysis relative to controlMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Celgene Corporation
Curated by ChEMBL
Celgene Corporation
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of mTOR (unknown origin) by HTR-FRET substrate phosphorylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of mTORC1 in human PC3 cells assessed as inhibition of S6 phosphorylation after 1 hrMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Celgene Corporation
Curated by ChEMBL
Celgene Corporation
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of mTOR (unknown origin) by HTR-FRET substrate phosphorylation assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Celgene Corporation
Curated by ChEMBL
Celgene Corporation
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of mTOR (unknown origin) by HTR-FRET substrate phosphorylation assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Celgene Corporation
Curated by ChEMBL
Celgene Corporation
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of mTOR (unknown origin) by HTR-FRET substrate phosphorylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of mTORC1 in human PC3 cells assessed as inhibition of S6 phosphorylation after 1 hrMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Celgene Corporation
Curated by ChEMBL
Celgene Corporation
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of mTOR (unknown origin) by HTR-FRET substrate phosphorylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of mTORC1 in human PC3 cells assessed as inhibition of S6 phosphorylation after 1 hrMore data for this Ligand-Target Pair
