Compile Data Set for Download or QSAR
Found 83 with Last Name = 'neve' and Initial = 'rm'
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM249277(US10017501, Compound 1020-18 | US9458145, 1020-18)copy SMILEScopy InChI
Affinity DataKi:  3.80nMAssay Description:Inhibition of Cy5-linked JQ1 probe binding to recombinant human N-terminal TEV-cleavable hexa-histidine tagged BRD4 bromodomain2 after 60 mins by HTR...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7ZZ6PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM249277(US10017501, Compound 1020-18 | US9458145, 1020-18)copy SMILEScopy InChI
Affinity DataKi:  7.5nMAssay Description:Inhibition of Cy5-linked JQ1 probe binding to recombinant human N-terminal TEV-cleavable hexa-histidine tagged BRD4 bromodomain1 after 60 mins by HTR...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7ZZ6PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM249277(US10017501, Compound 1020-18 | US9458145, 1020-18)copy SMILEScopy InChI
Affinity DataKi:  16nMAssay Description:Inhibition of tetra-acetylated Histone H4 peptide binding to recombinant human N-terminal TEV-cleavable hexa-histidine tagged BRD4 bromodomain1 after...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7ZZ6PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50380682(CHEMBL2017291 | I-BET151 (16))copy SMILEScopy InChI
Affinity DataKi:  61nMAssay Description:Inhibition of tetra-acetylated Histone H4 peptide binding to recombinant human N-terminal TEV-cleavable hexa-histidine tagged BRD4 bromodomain1 after...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50365463(CHEMBL1232461)copy SMILEScopy InChI
Affinity DataKi:  94nMAssay Description:Inhibition of Cy5-linked JQ1 probe binding to recombinant human N-terminal TEV-cleavable hexa-histidine tagged BRD4 bromodomain2 after 60 mins by HTR...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50365463(CHEMBL1232461)copy SMILEScopy InChI
Affinity DataKi:  163nMAssay Description:Inhibition of tetra-acetylated Histone H4 peptide binding to recombinant human N-terminal TEV-cleavable hexa-histidine tagged BRD4 bromodomain1 after...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50365463(CHEMBL1232461)copy SMILEScopy InChI
Affinity DataKi:  200nMAssay Description:Inhibition of Cy5-linked JQ1 probe binding to recombinant human N-terminal TEV-cleavable hexa-histidine tagged BRD4 bromodomain1 after 60 mins by HTR...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50380682(CHEMBL2017291 | I-BET151 (16))copy SMILEScopy InChI
Affinity DataKi:  385nMAssay Description:Inhibition of Cy5-linked JQ1 probe binding to recombinant human N-terminal TEV-cleavable hexa-histidine tagged BRD4 bromodomain2 after 60 mins by HTR...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50508319(CHEMBL4452415)copy SMILEScopy InChI
Affinity DataIC50: 76nMAssay Description:Inhibition of biotin-labelled tetra-acetylated Histone H4 peptide binding to recombinant human N-terminal TEV-cleavable hexa-histidine tagged BRD4 br...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7ZZ6PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM249277(US10017501, Compound 1020-18 | US9458145, 1020-18)copy SMILEScopy InChI
Affinity DataIC50: 78nMAssay Description:Inhibition of biotin-labelled tetra-acetylated Histone H4 peptide binding to recombinant human N-terminal TEV-cleavable hexa-histidine tagged BRD4 br...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7ZZ6PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50508318(CHEMBL4585758)copy SMILEScopy InChI
Affinity DataIC50: 79nMAssay Description:Inhibition of biotin-labelled tetra-acetylated Histone H4 peptide binding to recombinant human N-terminal TEV-cleavable hexa-histidine tagged BRD4 br...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7ZZ6PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM249277(US10017501, Compound 1020-18 | US9458145, 1020-18)copy SMILEScopy InChI
Affinity DataIC50: 83nMAssay Description:Inhibition of biotin-labelled tetra-acetylated Histone H4 peptide binding to recombinant human N-terminal TEV-cleavable hexa-histidine tagged BRD4 br...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7ZZ6PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50508318(CHEMBL4585758)copy SMILEScopy InChI
Affinity DataIC50: 84nMAssay Description:Inhibition of biotin-labelled tetra-acetylated Histone H4 peptide binding to recombinant human N-terminal TEV-cleavable hexa-histidine tagged BRD4 br...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7ZZ6PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50508319(CHEMBL4452415)copy SMILEScopy InChI
Affinity DataIC50: 99nMAssay Description:Inhibition of biotin-labelled tetra-acetylated Histone H4 peptide binding to recombinant human N-terminal TEV-cleavable hexa-histidine tagged BRD4 br...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7ZZ6PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM249286(US9458145, 1020-75)copy SMILEScopy InChI
Affinity DataIC50: 107nMAssay Description:Inhibition of biotin-labelled tetra-acetylated Histone H4 peptide binding to recombinant human N-terminal TEV-cleavable hexa-histidine tagged BRD4 br...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7ZZ6PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM249286(US9458145, 1020-75)copy SMILEScopy InChI
Affinity DataIC50: 144nMAssay Description:Inhibition of biotin-labelled tetra-acetylated Histone H4 peptide binding to recombinant human N-terminal TEV-cleavable hexa-histidine tagged BRD4 br...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7ZZ6PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50508320(CHEMBL4534568)copy SMILEScopy InChI
Affinity DataIC50: 148nMAssay Description:Inhibition of biotin-labelled tetra-acetylated Histone H4 peptide binding to recombinant human N-terminal TEV-cleavable hexa-histidine tagged BRD4 br...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7ZZ6PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50508328(CHEMBL4514501)copy SMILEScopy InChI
Affinity DataIC50: 203nMAssay Description:Inhibition of biotin-labelled tetra-acetylated Histone H4 peptide binding to recombinant human N-terminal TEV-cleavable hexa-histidine tagged BRD4 br...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7ZZ6PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50508320(CHEMBL4534568)copy SMILEScopy InChI
Affinity DataIC50: 219nMAssay Description:Inhibition of biotin-labelled tetra-acetylated Histone H4 peptide binding to recombinant human N-terminal TEV-cleavable hexa-histidine tagged BRD4 br...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7ZZ6PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50508317(CHEMBL4470445)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibition of biotin-labelled tetra-acetylated Histone H4 peptide binding to recombinant human N-terminal TEV-cleavable hexa-histidine tagged BRD4 br...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7ZZ6PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50508328(CHEMBL4514501)copy SMILEScopy InChI
Affinity DataIC50: 267nMAssay Description:Inhibition of biotin-labelled tetra-acetylated Histone H4 peptide binding to recombinant human N-terminal TEV-cleavable hexa-histidine tagged BRD4 br...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7ZZ6PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50508317(CHEMBL4470445)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibition of biotin-labelled tetra-acetylated Histone H4 peptide binding to recombinant human N-terminal TEV-cleavable hexa-histidine tagged BRD4 br...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7ZZ6PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50508316(CHEMBL4457320)copy SMILEScopy InChI
Affinity DataIC50: 342nMAssay Description:Inhibition of biotin-labelled tetra-acetylated Histone H4 peptide binding to recombinant human N-terminal TEV-cleavable hexa-histidine tagged BRD4 br...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7ZZ6PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50508316(CHEMBL4457320)copy SMILEScopy InChI
Affinity DataIC50: 420nMAssay Description:Inhibition of biotin-labelled tetra-acetylated Histone H4 peptide binding to recombinant human N-terminal TEV-cleavable hexa-histidine tagged BRD4 br...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7ZZ6PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50397635(CHEMBL2181721)copy SMILEScopy InChI
Affinity DataIC50: 503nMAssay Description:Inhibition of biotin-labelled tetra-acetylated Histone H4 peptide binding to recombinant human N-terminal TEV-cleavable hexa-histidine tagged BRD4 br...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7ZZ6PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50508326(CHEMBL4575459)copy SMILEScopy InChI
Affinity DataIC50: 596nMAssay Description:Inhibition of biotin-labelled tetra-acetylated Histone H4 peptide binding to recombinant human N-terminal TEV-cleavable hexa-histidine tagged BRD4 br...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7ZZ6PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50508326(CHEMBL4575459)copy SMILEScopy InChI
Affinity DataIC50: 905nMAssay Description:Inhibition of biotin-labelled tetra-acetylated Histone H4 peptide binding to recombinant human N-terminal TEV-cleavable hexa-histidine tagged BRD4 br...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7ZZ6PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50508329(CHEMBL4567623)copy SMILEScopy InChI
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of biotin-labelled tetra-acetylated Histone H4 peptide binding to recombinant human N-terminal TEV-cleavable hexa-histidine tagged BRD4 br...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7ZZ6PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50508321(CHEMBL4514160)copy SMILEScopy InChI
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of biotin-labelled tetra-acetylated Histone H4 peptide binding to recombinant human N-terminal TEV-cleavable hexa-histidine tagged BRD4 br...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7ZZ6PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50508321(CHEMBL4514160)copy SMILEScopy InChI
Affinity DataIC50: 1.43E+3nMAssay Description:Inhibition of biotin-labelled tetra-acetylated Histone H4 peptide binding to recombinant human N-terminal TEV-cleavable hexa-histidine tagged BRD4 br...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7ZZ6PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50508329(CHEMBL4567623)copy SMILEScopy InChI
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of biotin-labelled tetra-acetylated Histone H4 peptide binding to recombinant human N-terminal TEV-cleavable hexa-histidine tagged BRD4 br...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7ZZ6PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50397635(CHEMBL2181721)copy SMILEScopy InChI
Affinity DataIC50: 1.57E+3nMAssay Description:Inhibition of biotin-labelled tetra-acetylated Histone H4 peptide binding to recombinant human N-terminal TEV-cleavable hexa-histidine tagged BRD4 br...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7ZZ6PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50508327(CHEMBL4453726)copy SMILEScopy InChI
Affinity DataIC50: 1.65E+3nMAssay Description:Inhibition of biotin-labelled tetra-acetylated Histone H4 peptide binding to recombinant human N-terminal TEV-cleavable hexa-histidine tagged BRD4 br...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7ZZ6PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50508322(CHEMBL4569631)copy SMILEScopy InChI
Affinity DataIC50: 2.09E+3nMAssay Description:Inhibition of biotin-labelled tetra-acetylated Histone H4 peptide binding to recombinant human N-terminal TEV-cleavable hexa-histidine tagged BRD4 br...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7ZZ6PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50508327(CHEMBL4453726)copy SMILEScopy InChI
Affinity DataIC50: 2.53E+3nMAssay Description:Inhibition of biotin-labelled tetra-acetylated Histone H4 peptide binding to recombinant human N-terminal TEV-cleavable hexa-histidine tagged BRD4 br...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7ZZ6PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50508323(CHEMBL4544653)copy SMILEScopy InChI
Affinity DataIC50: 3.94E+3nMAssay Description:Inhibition of biotin-labelled tetra-acetylated Histone H4 peptide binding to recombinant human N-terminal TEV-cleavable hexa-histidine tagged BRD4 br...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7ZZ6PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50508322(CHEMBL4569631)copy SMILEScopy InChI
Affinity DataIC50: 9.38E+3nMAssay Description:Inhibition of biotin-labelled tetra-acetylated Histone H4 peptide binding to recombinant human N-terminal TEV-cleavable hexa-histidine tagged BRD4 br...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7ZZ6PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50508324(CHEMBL4583412)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of biotin-labelled tetra-acetylated Histone H4 peptide binding to recombinant human N-terminal TEV-cleavable hexa-histidine tagged BRD4 br...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7ZZ6PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50508323(CHEMBL4544653)copy SMILEScopy InChI
Affinity DataIC50: 1.63E+4nMAssay Description:Inhibition of biotin-labelled tetra-acetylated Histone H4 peptide binding to recombinant human N-terminal TEV-cleavable hexa-histidine tagged BRD4 br...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7ZZ6PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50508325(CHEMBL4443228)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of biotin-labelled tetra-acetylated Histone H4 peptide binding to recombinant human N-terminal TEV-cleavable hexa-histidine tagged BRD4 br...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7ZZ6PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50508324(CHEMBL4583412)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of biotin-labelled tetra-acetylated Histone H4 peptide binding to recombinant human N-terminal TEV-cleavable hexa-histidine tagged BRD4 br...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7ZZ6PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50508325(CHEMBL4443228)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of biotin-labelled tetra-acetylated Histone H4 peptide binding to recombinant human N-terminal TEV-cleavable hexa-histidine tagged BRD4 br...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7ZZ6PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM249277(US10017501, Compound 1020-18 | US9458145, 1020-18)copy SMILEScopy InChI
Affinity DataEC50:  55nMAssay Description:Inhibition of BRD4 in human MM1S cells assessed as reduction in MYC transcription measured after 6 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7ZZ6PubMed
TargetBromodomain-containing protein 2(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM249277(US10017501, Compound 1020-18 | US9458145, 1020-18)copy SMILEScopy InChI
Affinity DataKd:  0.590nMAssay Description:Binding affinity to human partial length BRD2 bromodomain 2 isoform 1 (E348 to D455 residues) expressed in bacterial expression system after 1 hr by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7ZZ6PubMed
TargetBromodomain-containing protein 8(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM249277(US10017501, Compound 1020-18 | US9458145, 1020-18)copy SMILEScopy InChI
Affinity DataKd:  5.90E+3nMAssay Description:Binding affinity to BRD8 bromodomain 1 (unknown origin) after 1 hr by bromoscan assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7ZZ6PubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM249277(US10017501, Compound 1020-18 | US9458145, 1020-18)copy SMILEScopy InChI
Affinity DataKd:  220nMAssay Description:Binding affinity to human partial length EP300 (A1040 to G1161 residues) expressed in bacterial expression system after 1 hr by bromoscan assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7ZZ6PubMed
TargetTranscription initiation factor TFIID subunit 1-like(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM249277(US10017501, Compound 1020-18 | US9458145, 1020-18)copy SMILEScopy InChI
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to human partial length TAF1L bromodomain 2 (Q1523 to D1654 residues) expressed in bacterial expression system after 1 hr by bromosc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7ZZ6PubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM249277(US10017501, Compound 1020-18 | US9458145, 1020-18)copy SMILEScopy InChI
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to human partial length ATAD2A (Q981 to R1108 residues) expressed in bacterial expression system after 1 hr by bromoscan assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7ZZ6PubMed
TargetBromodomain adjacent to zinc finger domain protein 2A(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM249277(US10017501, Compound 1020-18 | US9458145, 1020-18)copy SMILEScopy InChI
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to human partial length BAZ2A (M1792 to L1905 residues) expressed in bacterial expression system after 1 hr by bromoscan assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7ZZ6PubMed
TargetBromodomain adjacent to zinc finger domain protein 2B(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM249277(US10017501, Compound 1020-18 | US9458145, 1020-18)copy SMILEScopy InChI
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to human partial length BAZ2B (S2054 to S2168 residues) expressed in bacterial expression system after 1 hr by bromoscan assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7ZZ6PubMed
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