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Found 447 with Last Name = 'rodriguez-sarmiento' and Initial = 'rm'
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM120578(US8703768, 178)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:PDE10 activity of the compounds of the present invention was determined using a Scintillation Proximity Assay (SPA)-based method similar to the one p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P8X37US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM120577(US8703768, 177)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:PDE10 activity of the compounds of the present invention was determined using a Scintillation Proximity Assay (SPA)-based method similar to the one p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P8X37US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM120643(US8703768, 244)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:PDE10 activity of the compounds of the present invention was determined using a Scintillation Proximity Assay (SPA)-based method similar to the one p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P8X37US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM120672(Roche-Dataset for PDE10A, Compound 803 | US8703768...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:PDE10 activity of the compounds of the present invention was determined using a Scintillation Proximity Assay (SPA)-based method similar to the one p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P8X37US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM120583(Roche-Dataset for PDE10A, Compound 707 | US8703768...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:PDE10 activity of the compounds of the present invention was determined using a Scintillation Proximity Assay (SPA)-based method similar to the one p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P8X37US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM120698(Roche-Dataset for PDE10A, Compound 927 | US8703768...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:PDE10 activity of the compounds of the present invention was determined using a Scintillation Proximity Assay (SPA)-based method similar to the one p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P8X37US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM120727(Roche-Dataset for PDE10A, Compound 481 | US8703768...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:PDE10 activity of the compounds of the present invention was determined using a Scintillation Proximity Assay (SPA)-based method similar to the one p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P8X37US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM120559(US8703768, 159)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:PDE10 activity of the compounds of the present invention was determined using a Scintillation Proximity Assay (SPA)-based method similar to the one p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P8X37US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM120490(Roche-Dataset for PDE10A, Compound 743 | US8703768...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:PDE10 activity of the compounds of the present invention was determined using a Scintillation Proximity Assay (SPA)-based method similar to the one p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P8X37US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM120670(Roche-Dataset for PDE10A, Compound 852 | US8703768...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:PDE10 activity of the compounds of the present invention was determined using a Scintillation Proximity Assay (SPA)-based method similar to the one p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P8X37US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM120581(Roche-Dataset for PDE10A, Compound 553 | US8703768...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:PDE10 activity of the compounds of the present invention was determined using a Scintillation Proximity Assay (SPA)-based method similar to the one p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P8X37US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM120498(US8703768, 98)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:PDE10 activity of the compounds of the present invention was determined using a Scintillation Proximity Assay (SPA)-based method similar to the one p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P8X37US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM120481(Roche-Dataset for PDE10A, Compound 503 | US8703768...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:PDE10 activity of the compounds of the present invention was determined using a Scintillation Proximity Assay (SPA)-based method similar to the one p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P8X37US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM120674(Roche-Dataset for PDE10A, Compound 770 | US8703768...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:PDE10 activity of the compounds of the present invention was determined using a Scintillation Proximity Assay (SPA)-based method similar to the one p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P8X37US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM120520(US8703768, 120)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:PDE10 activity of the compounds of the present invention was determined using a Scintillation Proximity Assay (SPA)-based method similar to the one p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P8X37US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM120700(Roche-Dataset for PDE10A, Compound 902 | US8703768...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:PDE10 activity of the compounds of the present invention was determined using a Scintillation Proximity Assay (SPA)-based method similar to the one p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P8X37US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM120673(Roche-Dataset for PDE10A, Compound 599 | US8703768...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:PDE10 activity of the compounds of the present invention was determined using a Scintillation Proximity Assay (SPA)-based method similar to the one p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P8X37US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM120624(Roche-Dataset for PDE10A, Compound 933 | US8703768...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:PDE10 activity of the compounds of the present invention was determined using a Scintillation Proximity Assay (SPA)-based method similar to the one p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P8X37US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM120614(Roche-Dataset for PDE10A, Compound 464 | US8703768...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:PDE10 activity of the compounds of the present invention was determined using a Scintillation Proximity Assay (SPA)-based method similar to the one p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P8X37US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM120609(Roche-Dataset for PDE10A, Compound 539 | US8703768...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:PDE10 activity of the compounds of the present invention was determined using a Scintillation Proximity Assay (SPA)-based method similar to the one p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P8X37US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM120489(Roche-Dataset for PDE10A, Compound 997 | US8703768...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:PDE10 activity of the compounds of the present invention was determined using a Scintillation Proximity Assay (SPA)-based method similar to the one p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P8X37US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM120680(Roche-Dataset for PDE10A, Compound 798 | US8703768...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:PDE10 activity of the compounds of the present invention was determined using a Scintillation Proximity Assay (SPA)-based method similar to the one p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P8X37US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM120720(Roche-Dataset for PDE10A, Compound 329 | US8703768...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:PDE10 activity of the compounds of the present invention was determined using a Scintillation Proximity Assay (SPA)-based method similar to the one p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P8X37US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM120510(US8703768, 110)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:PDE10 activity of the compounds of the present invention was determined using a Scintillation Proximity Assay (SPA)-based method similar to the one p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P8X37US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM120612(Roche-Dataset for PDE10A, Compound 323 | US8703768...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:PDE10 activity of the compounds of the present invention was determined using a Scintillation Proximity Assay (SPA)-based method similar to the one p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P8X37US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM120691(Roche-Dataset for PDE10A, Compound 913 | US8703768...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:PDE10 activity of the compounds of the present invention was determined using a Scintillation Proximity Assay (SPA)-based method similar to the one p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P8X37US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM120661(Roche-Dataset for PDE10A, Compound 708 | US8703768...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:PDE10 activity of the compounds of the present invention was determined using a Scintillation Proximity Assay (SPA)-based method similar to the one p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P8X37US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM120711(Roche-Dataset for PDE10A, Compound 922 | US8703768...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:PDE10 activity of the compounds of the present invention was determined using a Scintillation Proximity Assay (SPA)-based method similar to the one p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P8X37US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM120687(Roche-Dataset for PDE10A, Compound 912 | US8703768...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:PDE10 activity of the compounds of the present invention was determined using a Scintillation Proximity Assay (SPA)-based method similar to the one p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P8X37US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM120615(Roche-Dataset for PDE10A, Compound 527 | US8703768...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:PDE10 activity of the compounds of the present invention was determined using a Scintillation Proximity Assay (SPA)-based method similar to the one p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P8X37US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM120558(US8703768, 158)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:PDE10 activity of the compounds of the present invention was determined using a Scintillation Proximity Assay (SPA)-based method similar to the one p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P8X37US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM120734(Roche-Dataset for PDE10A, Compound 740 | US8703768...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:PDE10 activity of the compounds of the present invention was determined using a Scintillation Proximity Assay (SPA)-based method similar to the one p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P8X37US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM120707(Roche-Dataset for PDE10A, Compound 702 | US8703768...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:PDE10 activity of the compounds of the present invention was determined using a Scintillation Proximity Assay (SPA)-based method similar to the one p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P8X37US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM120613(Roche-Dataset for PDE10A, Compound 536 | US8703768...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:PDE10 activity of the compounds of the present invention was determined using a Scintillation Proximity Assay (SPA)-based method similar to the one p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P8X37US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM97529(Roche-Dataset for PDE10A, Compound 46 | US8470820,...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.5Assay Description:Scintillation proximity assay using human PDE10A.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J96501US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM97501(Roche-Dataset for PDE10A, Compound 33 | US8470820,...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.5Assay Description:Scintillation proximity assay using human PDE10A.More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM97503(BDBM97509 | Roche-Dataset for PDE10A, Compound 13 ...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.5Assay Description:Scintillation proximity assay using human PDE10A.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J96501US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM97523(Roche-Dataset for PDE10A, Compound 107 | US8470820...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.5Assay Description:Scintillation proximity assay using human PDE10A.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J96501US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM97503(BDBM97509 | Roche-Dataset for PDE10A, Compound 13 ...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.5Assay Description:Scintillation proximity assay using human PDE10A.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J96501US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM97514(Roche-Dataset for PDE10A, Compound 6 | US8470820, ...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.5Assay Description:Scintillation proximity assay using human PDE10A.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J96501US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM97513(Roche-Dataset for PDE10A, Compound 77 | US8470820,...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.5Assay Description:Scintillation proximity assay using human PDE10A.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J96501US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM97521(Roche-Dataset for PDE10A, Compound 7 | US8470820, ...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.5Assay Description:Scintillation proximity assay using human PDE10A.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J96501US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM97527(Roche-Dataset for PDE10A, Compound 53 | US8470820,...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.5Assay Description:Scintillation proximity assay using human PDE10A.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J96501US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM97520(Roche-Dataset for PDE10A, Compound 8 | US8470820, ...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.5Assay Description:Scintillation proximity assay using human PDE10A.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J96501US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM97539(Roche-Dataset for PDE10A, Compound 953 | US8470820...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.5Assay Description:Scintillation proximity assay using human PDE10A.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J96501US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM97517(Roche-Dataset for PDE10A, Compound 44 | US8470820,...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.5Assay Description:Scintillation proximity assay using human PDE10A.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J96501US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM120701(Roche-Dataset for PDE10A, Compound 755 | US8703768...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:PDE10 activity of the compounds of the present invention was determined using a Scintillation Proximity Assay (SPA)-based method similar to the one p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P8X37US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM120542(US8703768, 142)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:PDE10 activity of the compounds of the present invention was determined using a Scintillation Proximity Assay (SPA)-based method similar to the one p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P8X37US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM120514(US8703768, 114)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:PDE10 activity of the compounds of the present invention was determined using a Scintillation Proximity Assay (SPA)-based method similar to the one p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P8X37US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM120505(US8703768, 105)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:PDE10 activity of the compounds of the present invention was determined using a Scintillation Proximity Assay (SPA)-based method similar to the one p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P8X37US Patent
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