Compile Data Set for Download or QSAR
Found 277 with Last Name = 'rutledge' and Initial = 'rz'
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Department of Medicinal Chemistry Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50184069(CHEMBL207197 | N-((R)-1-((S)-6-amino-1-oxo-1-(4-(p...)copy SMILEScopy InChI
Affinity DataKi:  0.00500nMAssay Description:Displacement of [125I]CGRP from human cloned CLR/RAMP1 receptor expressed in E10 cellsMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50356281(CHEMBL1910953)copy SMILEScopy InChI
Affinity DataKi:  0.0100nMAssay Description:Displacement of [125I]adrenomedullin form CGRP receptor in human SK-N-MC cell membrane by competitive binding assay in the absence of MgCl2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5H25PubMed
TargetCalcitonin gene-related peptide 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50356281(CHEMBL1910953)copy SMILEScopy InChI
Affinity DataKi:  0.0100nMAssay Description:Displacement of [125I]adrenomedullin form CGRP receptor in human SK-N-MC cell membrane by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5H25PubMed
TargetCalcitonin gene-related peptide 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184069(CHEMBL207197 | N-((R)-1-((S)-6-amino-1-oxo-1-(4-(p...)copy SMILEScopy InChI
Affinity DataKi:  0.0140nMAssay Description:Displacement of [125I]adrenomedullin form CGRP receptor in human SK-N-MC cell membrane by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5H25PubMed
TargetCalcitonin gene-related peptide 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50356282(CHEMBL1910936)copy SMILEScopy InChI
Affinity DataKi:  0.0240nMAssay Description:Displacement of [125I]adrenomedullin form CGRP receptor in human SK-N-MC cell membrane by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5H25PubMed
TargetCalcitonin gene-related peptide 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50224431(CHEMBL236593 | MK-0974 | N-[(3R,6S)-6-(2,3-difluor...)copy SMILEScopy InChI
Affinity DataKi:  0.780nMAssay Description:Displacement of [125I]adrenomedullin form CGRP receptor in human SK-N-MC cell membrane by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5H25PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192553((R)-4-(4-(3-methoxyphenyl)-2-oxo-2,3-dihydroimidaz...)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:Displacement of [125I]CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1QNXPubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Department of Medicinal Chemistry Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50217493(CHEMBL235237 | N-((3R,6S)-1-(cyclopropylmethyl)-2-...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Displacement of [125I]CGRP from human CL receptor in RAMP1 membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9Q4DPubMed
TargetCalcitonin gene-related peptide 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50000743(CHEMBL525571 | [Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Se...)copy SMILEScopy InChI
Affinity DataKi:  4.5nMAssay Description:Displacement of [125I]adrenomedullin form CGRP receptor in human SK-N-MC cell membrane by competitive binding assay in the absence of MgCl2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5H25PubMed
TargetCalcitonin gene-related peptide 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50000743(CHEMBL525571 | [Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Se...)copy SMILEScopy InChI
Affinity DataKi:  5.5nMAssay Description:Displacement of [125I]adrenomedullin form CGRP receptor in human SK-N-MC cell membrane by competitive binding assay in presence of 5 mM MgCl2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5H25PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192539((R)-4-(2-oxo-4-p-tolyl-2,3-dihydroimidazol-1-yl)-N...)copy SMILEScopy InChI
Affinity DataKi:  6.30nMAssay Description:Displacement of [125I]CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1QNXPubMed
TargetCalcitonin gene-related peptide 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50356279(CHEMBL1910937)copy SMILEScopy InChI
Affinity DataKi:  8nMAssay Description:Displacement of [125I]adrenomedullin form CGRP receptor in human SK-N-MC cell membrane by competitive binding assay in the absence of MgCl2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5H25PubMed
TargetCalcitonin gene-related peptide 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50356279(CHEMBL1910937)copy SMILEScopy InChI
Affinity DataKi:  9nMAssay Description:Displacement of [125I]adrenomedullin form CGRP receptor in human SK-N-MC cell membrane by competitive binding assay in presence of 5 mM MgCl2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5H25PubMed
TargetCalcitonin gene-related peptide 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50356279(CHEMBL1910937)copy SMILEScopy InChI
Affinity DataKi:  9.30nMAssay Description:Displacement of [125I]adrenomedullin form CGRP receptor in human SK-N-MC cell membrane by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5H25PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192542((R)-4-(4-(4-fluorophenyl)-2-oxo-2,3-dihydroimidazo...)copy SMILEScopy InChI
Affinity DataKi:  11nMAssay Description:Displacement of [125I]CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1QNXPubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192564((R)-4-(2-oxo-4-phenyl-2,3-dihydroimidazol-1-yl)-N-...)copy SMILEScopy InChI
Affinity DataKi:  11nMAssay Description:Displacement of [125I]CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1QNXPubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192551((R)-4-(4-(3-fluorophenyl)-2-oxo-2,3-dihydroimidazo...)copy SMILEScopy InChI
Affinity DataKi:  11nMAssay Description:Displacement of [125I]CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1QNXPubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192540((R)-4-(4-(4-(difluoromethoxy)phenyl)-2-oxo-2,3-dih...)copy SMILEScopy InChI
Affinity DataKi:  19nMAssay Description:Displacement of [125I]CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1QNXPubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192559((R)-4-(2-oxo-2,3-dihydroimidazo[4,5-b]pyridin-1-yl...)copy SMILEScopy InChI
Affinity DataKi:  23nMAssay Description:Displacement of [125I]CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1QNXPubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Department of Medicinal Chemistry Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50217495(CHEMBL429262 | N-((3R,6S)-1-(cyclopropylmethyl)-2-...)copy SMILEScopy InChI
Affinity DataKi:  25nMAssay Description:Displacement of [125I]CGRP from human CL receptor in RAMP1 membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9Q4DPubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192576((R)-4-(5-oxo-3-phenyl-4,5-dihydro-1,2,4-triazol-1-...)copy SMILEScopy InChI
Affinity DataKi:  26nMAssay Description:Displacement of [125I]CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1QNXPubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192571((R)-4-(2-oxo-4-(pyridin-2-yl)-2,3-dihydroimidazol-...)copy SMILEScopy InChI
Affinity DataKi:  27nMAssay Description:Displacement of [125I]CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1QNXPubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192570((R)-4-(2-oxo-1,2-dihydronaphtho[1,2-d]imidazol-3-y...)copy SMILEScopy InChI
Affinity DataKi:  27nMAssay Description:Displacement of [125I]CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1QNXPubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192575((R)-4-(2,4-dioxoimidazolidin-1-yl)-N-(2-oxo-5-phen...)copy SMILEScopy InChI
Affinity DataKi:  29nMAssay Description:Displacement of [125I]CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1QNXPubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Department of Medicinal Chemistry Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50217485(CHEMBL394229 | N-((3R,6S)-1-(cyclopropylmethyl)-2-...)copy SMILEScopy InChI
Affinity DataKi:  29nMAssay Description:Displacement of [125I]CGRP from human CL receptor in RAMP1 membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9Q4DPubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Department of Medicinal Chemistry Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50217488(CHEMBL392132 | N-((3R,6S)-1-(cyclopropylmethyl)-2-...)copy SMILEScopy InChI
Affinity DataKi:  29nMAssay Description:Displacement of [125I]CGRP from human CL receptor in RAMP1 membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9Q4DPubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Department of Medicinal Chemistry Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50217486((cis racemic)-N-(1-(cyclopropylmethyl)-2-oxo-6-phe...)copy SMILEScopy InChI
Affinity DataKi:  31nMAssay Description:Displacement of [125I]CGRP from human CL receptor in RAMP1 membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9Q4DPubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Department of Medicinal Chemistry Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50217486((cis racemic)-N-(1-(cyclopropylmethyl)-2-oxo-6-phe...)copy SMILEScopy InChI
Affinity DataKi:  31nMAssay Description:Displacement of [125I]CGRP from human CL receptor in RAMP1 membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9Q4DPubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Department of Medicinal Chemistry Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50217483((cis racemic)-N-(1-(cyclopropylmethyl)-2-oxo-5-phe...)copy SMILEScopy InChI
Affinity DataKi:  35nMAssay Description:Displacement of [125I]CGRP from human CL receptor in RAMP1 membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9Q4DPubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Department of Medicinal Chemistry Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50217483((cis racemic)-N-(1-(cyclopropylmethyl)-2-oxo-5-phe...)copy SMILEScopy InChI
Affinity DataKi:  35nMAssay Description:Displacement of [125I]CGRP from human CL receptor in RAMP1 membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9Q4DPubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Department of Medicinal Chemistry Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50184071((R)-4-(2-oxo-1,2-dihydroquinazolin-3(4H)-yl)-N-(2-...)copy SMILEScopy InChI
Affinity DataKi:  44nMAssay Description:Displacement of [125I]CGRP from human cloned CLR/RAMP1 receptor expressed in E10 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2NX8PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184071((R)-4-(2-oxo-1,2-dihydroquinazolin-3(4H)-yl)-N-(2-...)copy SMILEScopy InChI
Affinity DataKi:  48nMAssay Description:Displacement of [125I]CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1QNXPubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192538((R)-N-(2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)-2,3...)copy SMILEScopy InChI
Affinity DataKi:  51nMAssay Description:Displacement of [125I]CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1QNXPubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Department of Medicinal Chemistry Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50217498((R,Z)-N-(1-isopropyl-2-oxo-5-phenyl-2,3-dihydro-1H...)copy SMILEScopy InChI
Affinity DataKi:  55nMAssay Description:Displacement of [125I]CGRP from human CL receptor in RAMP1 membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9Q4DPubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Department of Medicinal Chemistry Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50184072((R)-4-(2-oxo-1,2,4,5-tetrahydrobenzo[d][1,3]diazep...)copy SMILEScopy InChI
Affinity DataKi:  61nMAssay Description:Displacement of [125I]CGRP from human cloned CLR/RAMP1 receptor expressed in E10 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2NX8PubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Department of Medicinal Chemistry Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50184074((R)-N-(3-(3,5-dibromo-4-hydroxyphenyl)-1-oxo-1-(4-...)copy SMILEScopy InChI
Affinity DataKi:  83nMAssay Description:Displacement of [125I]CGRP from human cloned CLR/RAMP1 receptor expressed in E10 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2NX8PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192552((R)-4-(2-oxo-4-(4-(trifluoromethoxy)phenyl)-2,3-di...)copy SMILEScopy InChI
Affinity DataKi:  104nMAssay Description:Displacement of [125I]CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1QNXPubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192561((R)-methyl 1-(1-((2-oxo-5-phenyl-1-(2,2,2-trifluor...)copy SMILEScopy InChI
Affinity DataKi:  110nMAssay Description:Displacement of [125I]CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1QNXPubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192569((R)-4-(4-chloro-2-oxo-2,3-dihydrobenzo[d]imidazol-...)copy SMILEScopy InChI
Affinity DataKi:  143nMAssay Description:Displacement of [125I]CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1QNXPubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192555((R)-4-(2-oxo-2,3-dihydroimidazo[4,5-b]pyrazin-1-yl...)copy SMILEScopy InChI
Affinity DataKi:  156nMAssay Description:Displacement of [125I]CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1QNXPubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192568((R)-4-(4-(4-methoxyphenyl)-2-oxo-2,3-dihydroimidaz...)copy SMILEScopy InChI
Affinity DataKi:  205nMAssay Description:Displacement of [125I]CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1QNXPubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192560((R)-4-(5-(methylsulfonyl)-2-oxo-2,3-dihydrobenzo[d...)copy SMILEScopy InChI
Affinity DataKi:  260nMAssay Description:Displacement of [125I]CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1QNXPubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Department of Medicinal Chemistry Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50217491((cis racemic)-N-((3R)-1-(cyclopropylmethyl)-2-oxo-...)copy SMILEScopy InChI
Affinity DataKi:  266nMAssay Description:Displacement of [125I]CGRP from human CL receptor in RAMP1 membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9Q4DPubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Department of Medicinal Chemistry Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50217491((cis racemic)-N-((3R)-1-(cyclopropylmethyl)-2-oxo-...)copy SMILEScopy InChI
Affinity DataKi:  266nMAssay Description:Displacement of [125I]CGRP from human CL receptor in RAMP1 membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9Q4DPubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192558((R)-4-(2-oxo-1,2-dihydropyrido[2,3-d]pyrimidin-3(4...)copy SMILEScopy InChI
Affinity DataKi:  295nMAssay Description:Displacement of [125I]CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1QNXPubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192554((R)-4-(2-oxo-1,2-dihydropyrido[4,3-d]pyrimidin-3(4...)copy SMILEScopy InChI
Affinity DataKi:  320nMAssay Description:Displacement of [125I]CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1QNXPubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192573(4-(2-oxo-4-phenylimidazolidin-1-yl)-N-((R)-2-oxo-5...)copy SMILEScopy InChI
Affinity DataKi:  339nMAssay Description:Displacement of [125I]CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1QNXPubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192579((R)-4-(2-oxo-1,2-dihydropyrido[3,4-d]pyrimidin-3(4...)copy SMILEScopy InChI
Affinity DataKi:  350nMAssay Description:Displacement of [125I]CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1QNXPubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192550((R)-4-(4-fluoro-2-oxo-2,3-dihydrobenzo[d]imidazol-...)copy SMILEScopy InChI
Affinity DataKi:  375nMAssay Description:Displacement of [125I]CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1QNXPubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192581((R)-4-(2-oxo-1,2-dihydroimidazo[4,5-b]pyridin-3-yl...)copy SMILEScopy InChI
Affinity DataKi:  427nMAssay Description:Displacement of [125I]CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1QNXPubMed
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