Compile Data Set for Download or QSAR
Found 27 with Last Name = 'bokan' and Initial = 's'
TargetInterleukin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50575333(CHEMBL4857063)copy SMILES
Affinity DataIC50: 8nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
TargetInterleukin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50575331(CHEMBL4868242)copy SMILES
Affinity DataIC50: 11nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
TargetInterleukin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50575332(CHEMBL4869725)copy SMILES
Affinity DataIC50: 14nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
TargetInterleukin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50575328(CHEMBL4868367)copy SMILES
Affinity DataIC50: 32nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
TargetInterleukin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50575327(CHEMBL4848840)copy SMILES
Affinity DataIC50: 34nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
TargetInterleukin-2(Homo sapiens (Human))TBA
LigandPNGBDBM387265(2,6- Difluoro-N-(2′- methyl-5′-(4-meth...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
TargetInterleukin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50575326(CHEMBL4868517)copy SMILES
Affinity DataIC50: 50nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
TargetInterleukin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50575329(CHEMBL4859192)copy SMILES
Affinity DataIC50: 55nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
TargetInterleukin-2(Homo sapiens (Human))TBA
LigandPNGBDBM387270(2,6- Difluoro-N-(5-(2- methyl-5-(4- methyl-5-oxo-4...)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
TargetInterleukin-2(Homo sapiens (Human))TBA
LigandPNGBDBM387269(2- Chloro-N-(5-(5-(5,5- dimethyl-4-oxo-4,5- dihydr...)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
TargetInterleukin-2(Homo sapiens (Human))TBA
LigandPNGBDBM387261(N-(5′- (5,5-Dimethyl-4-oxo- 4,5-dihydroisoxa...)copy SMILEScopy InChI
Affinity DataIC50: 69nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
LigandPNGBDBM50575331(CHEMBL4868242)copy SMILES
Affinity DataIC50: 76nMAssay Description:Inhibition of Orai1/STIM1 (unknown origin) expressed in HEK293 cells assessed as reduction in Ca2+-release activated Ca2+ entry current by manual pat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
TargetInterleukin-2(Homo sapiens (Human))TBA
LigandPNGBDBM387266(N-(5′- (4-Ethyl-5-oxo-4,5- dihydro-1,3,4- ...)copy SMILEScopy InChI
Affinity DataIC50: 78nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
TargetInterleukin-2(Homo sapiens (Human))TBA
LigandPNGBDBM387272(N-(5-(5- (5,5-dimethyl-4-oxo- 4,5-dihydroisoxazol-...)copy SMILEScopy InChI
Affinity DataIC50: 94nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
LigandPNGBDBM50575336(CHEMBL4753998)copy SMILES
Affinity DataIC50: 119nMAssay Description:Inhibition of Orai1/STIM1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
TargetInterleukin-2(Homo sapiens (Human))TBA
LigandPNGBDBM387297(US10292981, Example 121)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
TargetInterleukin-2(Homo sapiens (Human))TBA
LigandPNGBDBM387294(US10292981, Example 78)copy SMILEScopy InChI
Affinity DataIC50: 171nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
TargetInterleukin-2(Homo sapiens (Human))TBA
LigandPNGBDBM387281(N-(5-(5- (5,5-Dimethyl-4-oxo- 4,5-dihydroisoxazol-...)copy SMILEScopy InChI
Affinity DataIC50: 178nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
TargetInterleukin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50575331(CHEMBL4868242)copy SMILES
Affinity DataIC50: 183nMAssay Description:Inhibition of IL2 in thapsigargin stimulated human whole bloodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
TargetInterleukin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50575330(CHEMBL4872805)copy SMILES
Affinity DataIC50: 227nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
TargetInterleukin-2(Homo sapiens (Human))TBA
LigandPNGBDBM387290(N-(5- (5,5-Dimethyl-4,5- dihydroisoxazol-3- yl)-2-...)copy SMILEScopy InChI
Affinity DataIC50: 328nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
TargetTumor necrosis factor(Homo sapiens (Human))TBA
LigandPNGBDBM50575331(CHEMBL4868242)copy SMILES
Affinity DataIC50: 695nMAssay Description:Inhibition of TNF-alpha in thapsigargin stimulated human whole bloodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
LigandPNGBDBM50575336(CHEMBL4753998)copy SMILES
Affinity DataIC50: 895nMAssay Description:Inhibition of Orai2/STIM1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
LigandPNGBDBM50575334(CHEMBL4863881)copy SMILES
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Orai1/STIM1 (unknown origin) expressed in HEK293 cells assessed as reduction in Ca2+-release activated Ca2+ entry current by manual pat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
LigandPNGBDBM50575335(CHEMBL4570175)copy SMILES
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human STIM1/Orai3 expressed in HEK293 cells assessed as reduction in Orai3 current by electrophysiological methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
LigandPNGBDBM50575335(CHEMBL4570175)copy SMILES
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human STIM1/Orai1 expressed in HEK293 cells assessed as reduction in Orai1 current by electrophysiological methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
LigandPNGBDBM50575331(CHEMBL4868242)copy SMILES
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ERG by FLIPR TETRA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed