Found 133 with Last Name = 'capacchi' and Initial = 's' TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Universit£ degli Studi di Parma
Curated by ChEMBL
Universit£ degli Studi di Parma
Curated by ChEMBL
Affinity DataKi: 1.58nMAssay Description:Inhibition of human recombinant full length N-terminal His6-tagged PI3K p110delta/p85alpha expressed in baculovirus infected Sf9 insect cells using P...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Universit£ degli Studi di Parma
Curated by ChEMBL
Universit£ degli Studi di Parma
Curated by ChEMBL
Affinity DataKi: 3.16nMAssay Description:Inhibition of human recombinant full length N-terminal His6-tagged PI3K p110delta/p85alpha expressed in baculovirus infected Sf9 insect cells using P...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Universit£ degli Studi di Parma
Curated by ChEMBL
Universit£ degli Studi di Parma
Curated by ChEMBL
Affinity DataKi: 12.6nMAssay Description:Inhibition of human recombinant full length N-terminal His6-tagged PI3K p110delta/p85alpha expressed in baculovirus infected Sf9 insect cells using P...More data for this Ligand-Target Pair
3D Structure (crystal)TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Universit£ degli Studi di Parma
Curated by ChEMBL
Universit£ degli Studi di Parma
Curated by ChEMBL
Affinity DataKi: 12.6nMAssay Description:Inhibition of human recombinant full length N-terminal His6-tagged PI3K p110delta/p85alpha expressed in baculovirus infected Sf9 insect cells using P...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Universit£ degli Studi di Parma
Curated by ChEMBL
Universit£ degli Studi di Parma
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Inhibition of [3H](S)-sulpiride binding in striatal homogenates of rat brainMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Universit£ degli Studi di Parma
Curated by ChEMBL
Universit£ degli Studi di Parma
Curated by ChEMBL
Affinity DataKi: 25nMAssay Description:Inhibition of 0.1 nM of [125I]- (S)-N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2-methoxy-benzamide binding in striatal homogenates of rat brainMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Universit£ degli Studi di Parma
Curated by ChEMBL
Universit£ degli Studi di Parma
Curated by ChEMBL
Affinity DataKi: 125nMAssay Description:Inhibition of human recombinant full length N-terminal His6-tagged PI3K p110delta/p85alpha expressed in baculovirus infected Sf9 insect cells using P...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Affinity DataIC50: 0.0280nMAssay Description:Inhibition of human recombinant PDE4B expressed insect sf9 cells by radiometric assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of PDE4 activity in human PBMC assessed as inhibition of LPS-induced TNFalpha release after 18 hrs by ELISAMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of PDE4 activity in human PBMC assessed as inhibition of LPS-induced TNFalpha release after 18 hrs by ELISAMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of PDE4 activity in human PBMC assessed as inhibition of LPS-induced TNFalpha release after 18 hrs by ELISAMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Affinity DataIC50: 0.0720nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Affinity DataIC50: 0.0880nMAssay Description:Inhibition of human recombinant PDE4B expressed insect sf9 cells by radiometric assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Affinity DataIC50: 0.110nMAssay Description:Inhibition of PDE4 activity in human PBMC assessed as inhibition of LPS-induced TNFalpha release after 18 hrs by ELISAMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Affinity DataIC50: 0.120nMAssay Description:Inhibition of PDE4 activity in human PBMC assessed as inhibition of LPS-induced TNFalpha release after 18 hrs by ELISAMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Affinity DataIC50: 0.120nMAssay Description:Inhibition of PDE4 activity in human PBMC assessed as inhibition of LPS-induced TNFalpha release after 18 hrs by ELISAMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Affinity DataIC50: 0.130nMAssay Description:Inhibition of PDE4 activity in human PBMC assessed as inhibition of LPS-induced TNFalpha release after 18 hrs by ELISAMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Affinity DataIC50: 0.130nMAssay Description:Inhibition of PDE4 activity in human PBMC assessed as inhibition of LPS-induced TNFalpha release after 18 hrs by ELISAMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Affinity DataIC50: 0.130nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Affinity DataIC50: 0.140nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Affinity DataIC50: 0.150nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Affinity DataIC50: 0.160nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Affinity DataIC50: 0.170nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Affinity DataIC50: 0.180nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Affinity DataIC50: 0.210nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Affinity DataIC50: 0.210nMAssay Description:Inhibition of PDE4 activity in human PBMC assessed as inhibition of LPS-induced TNFalpha release after 18 hrs by ELISAMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Chiesi Farmaceutici S.p.A.
Curated by ChEMBL
Affinity DataIC50: 0.210nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
