Compile Data Set for Download or QSAR
Found 351 with Last Name = 'chalon' and Initial = 's'
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
INSERM

Curated by ChEMBL
LigandPNGBDBM50073436((2-(2-((dimethylamino)methyl)phenylthio)-5-iodophe...)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:Displacement of [125I]IPT from SERT in rat brain cortex membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0M3JPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£ d'Orl£ans

Curated by ChEMBL
LigandPNGBDBM50513620(CHEMBL4563574)copy SMILEScopy InChI
Affinity DataKi:  0.200nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from alpha7 nAChR in Wistar rat brain membrane incubated for 3 hrs by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49V3XPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£ d'Orl£ans

Curated by ChEMBL
LigandPNGBDBM50513605(CHEMBL4563839)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from alpha7 nAChR in Wistar rat brain membrane incubated for 3 hrs by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49V3XPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£ d'Orl£ans

Curated by ChEMBL
LigandPNGBDBM50513617(CHEMBL4459802)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from alpha7 nAChR in Wistar rat brain membrane incubated for 3 hrs by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49V3XPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£ d'Orl£ans

Curated by ChEMBL
LigandPNGBDBM50513594(CHEMBL4556722)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from alpha7 nAChR in Wistar rat brain membrane incubated for 3 hrs by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49V3XPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£ d'Orl£ans

Curated by ChEMBL
LigandPNGBDBM50513583(CHEMBL4533685)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from alpha7 nAChR in Wistar rat brain membrane incubated for 3 hrs by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49V3XPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
INSERM

Curated by ChEMBL
LigandPNGBDBM50110577(2-(2-((dimethylamino)methyl)phenylthio)-5-iodoanil...)copy SMILEScopy InChI
Affinity DataKi:  0.400nMAssay Description:Inhibition of [3H]-paroxetine binding to serotonin transporter (SERT) of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TH8M15PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
INSERM

Curated by ChEMBL
LigandPNGBDBM50178936(2-(2-((dimethylamino)methyl)phenoxy)-5-methylbenze...)copy SMILEScopy InChI
Affinity DataKi:  0.530nMAssay Description:Displacement of [3H]paroxetine from SERTMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z037R6PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£ d'Orl£ans

Curated by ChEMBL
LigandPNGBDBM50513613(CHEMBL4567300)copy SMILEScopy InChI
Affinity DataKi:  0.600nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from alpha7 nAChR in Wistar rat brain membrane incubated for 3 hrs by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49V3XPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£ d'Orl£ans

Curated by ChEMBL
LigandPNGBDBM50513577(CHEMBL4445961)copy SMILEScopy InChI
Affinity DataKi:  0.700nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from alpha7 nAChR in Wistar rat brain membrane incubated for 3 hrs by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49V3XPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
INSERM U316

Curated by PDSP Ki Database
LigandPNGBDBM50057628((2S,8R)-3-(3,4-Dichloro-phenyl)-8-((E)-3-iodo-ally...)copy SMILEScopy InChI
Affinity DataKi:  0.700nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X928VCPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£ d'Orl£ans

Curated by ChEMBL
LigandPNGBDBM50513611(CHEMBL4452867)copy SMILEScopy InChI
Affinity DataKi:  0.800nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from alpha7 nAChR in Wistar rat brain membrane incubated for 3 hrs by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49V3XPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
INSERM

Curated by ChEMBL
LigandPNGBDBM22416((3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-f...)copy SMILEScopy InChI
Affinity DataKi:  0.800nMMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
INSERM

Curated by ChEMBL
LigandPNGBDBM50264817(CHEMBL491028 | N-(5-chloro-2-(2-((dimethylamino)me...)copy SMILEScopy InChI
Affinity DataKi:  0.900nMAssay Description:Displacement of [125I]IDAM from SERT in rat brain cortex membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0M3JPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£ d'Orl£ans

Curated by ChEMBL
LigandPNGBDBM50513606(CHEMBL4547917)copy SMILEScopy InChI
Affinity DataKi:  0.900nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from alpha7 nAChR in Wistar rat brain membrane incubated for 3 hrs by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49V3XPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
INSERM

Curated by ChEMBL
LigandPNGBDBM50110782(CHEMBL429065 | [5-Iodo-2-(2-methylaminomethyl-phen...)copy SMILEScopy InChI
Affinity DataKi:  0.980nMAssay Description:Inhibition of [3H]-paroxetine binding to serotonin transporter (SERT) of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TH8M15PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
INSERM

Curated by ChEMBL
LigandPNGBDBM50110780(5-Iodo-2-(2-methylaminomethyl-phenylsulfanyl)-phen...)copy SMILEScopy InChI
Affinity DataKi:  1.25nMAssay Description:Inhibition of [3H]-paroxetine binding to serotonin transporter (SERT) of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TH8M15PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£ d'Orl£ans

Curated by ChEMBL
LigandPNGBDBM50500420(CHEMBL3746010)copy SMILEScopy InChI
Affinity DataKi:  1.30nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAchR in rat frontal corticesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TF01CWPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£ d'Orl£ans

Curated by ChEMBL
LigandPNGBDBM50513616(CHEMBL4532801)copy SMILEScopy InChI
Affinity DataKi:  1.40nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from alpha7 nAChR in Wistar rat brain membrane incubated for 3 hrs by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49V3XPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£ d'Orl£ans

Curated by ChEMBL
LigandPNGBDBM50513579(CHEMBL4534225)copy SMILEScopy InChI
Affinity DataKi:  1.40nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from alpha7 nAChR in Wistar rat brain membrane incubated for 3 hrs by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49V3XPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
INSERM

Curated by ChEMBL
LigandPNGBDBM50110777(5-Bromo-2-(2-methylaminomethyl-phenylsulfanyl)-phe...)copy SMILEScopy InChI
Affinity DataKi:  1.49nMAssay Description:Inhibition of [3H]-paroxetine binding to serotonin transporter (SERT) of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TH8M15PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£ d'Orl£ans

Curated by ChEMBL
LigandPNGBDBM50513585(CHEMBL4467924)copy SMILEScopy InChI
Affinity DataKi:  1.5nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from alpha7 nAChR in Wistar rat brain membrane incubated for 3 hrs by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49V3XPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£ d'Orl£ans

Curated by ChEMBL
LigandPNGBDBM50513592(CHEMBL4517968)copy SMILEScopy InChI
Affinity DataKi:  1.5nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from alpha7 nAChR in Wistar rat brain membrane incubated for 3 hrs by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49V3XPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
INSERM U316

Curated by PDSP Ki Database
LigandPNGBDBM22167(1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)pip...)copy SMILEScopy InChI
Affinity DataKi:  1.60nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X928VCPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
INSERM

Curated by ChEMBL
LigandPNGBDBM50110788(2-(2-((dimethylamino)methyl)phenylthio)-5-methylan...)copy SMILEScopy InChI
Affinity DataKi:  1.65nMAssay Description:Inhibition of [3H]-paroxetine binding to serotonin transporter (SERT) of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TH8M15PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
INSERM

Curated by ChEMBL
LigandPNGBDBM50110788(2-(2-((dimethylamino)methyl)phenylthio)-5-methylan...)copy SMILEScopy InChI
Affinity DataKi:  1.65nMAssay Description:Displacement of [3H]paroxetine from SERTMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z037R6PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
INSERM

Curated by ChEMBL
LigandPNGBDBM50110788(2-(2-((dimethylamino)methyl)phenylthio)-5-methylan...)copy SMILEScopy InChI
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]MADAM from SERT in rat brain cortex membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0M3JPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
INSERM

Curated by ChEMBL
LigandPNGBDBM50110788(2-(2-((dimethylamino)methyl)phenylthio)-5-methylan...)copy SMILEScopy InChI
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]paroxetine from SERT in rat brain cortex membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0M3JPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£ d'Orl£ans

Curated by ChEMBL
LigandPNGBDBM50513584(CHEMBL4583910)copy SMILEScopy InChI
Affinity DataKi:  1.70nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from alpha7 nAChR in Wistar rat brain membrane incubated for 3 hrs by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49V3XPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£ d'Orl£ans

Curated by ChEMBL
LigandPNGBDBM50513588(CHEMBL4582749)copy SMILEScopy InChI
Affinity DataKi:  1.90nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from alpha7 nAChR in Wistar rat brain membrane incubated for 3 hrs by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49V3XPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
INSERM

Curated by ChEMBL
LigandPNGBDBM50073438(CHEMBL278165 | [5-Bromo-2-(2-dimethylaminomethyl-p...)copy SMILEScopy InChI
Affinity DataKi:  1.92nMAssay Description:Inhibition of [3H]-paroxetine binding to serotonin transporter (SERT) of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TH8M15PubMed
TargetAmyloid-beta precursor protein [1-42](Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM50492518(Florbetapir | US10906900, AV45)copy SMILEScopy InChI
Affinity DataKi:  2.20nMAssay Description:Table 5: Fresh solutions of the test compounds (2.5 mM in DMSO) are diluted in PBS pH7.4, at concentrations between 0.5 nM and 5 μM in the prese...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC42NCUS Patent
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
INSERM

Curated by ChEMBL
LigandPNGBDBM50110781(5-Bromo-2-(2-dimethylaminomethyl-phenylsulfanyl)-p...)copy SMILEScopy InChI
Affinity DataKi:  2.23nMAssay Description:Inhibition of [3H]-paroxetine binding to serotonin transporter (SERT) of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TH8M15PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£ d'Orl£ans

Curated by ChEMBL
LigandPNGBDBM50500406(CHEMBL3746146)copy SMILEScopy InChI
Affinity DataKi:  2.30nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAchR in rat frontal corticesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TF01CWPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
INSERM U316

Curated by PDSP Ki Database
LigandPNGBDBM22167(1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)pip...)copy SMILEScopy InChI
Affinity DataKi:  2.40nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8CFZPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
INSERM

Curated by ChEMBL
LigandPNGBDBM50110784(CHEMBL284002 | [2-(4-Iodo-2-methoxymethyl-phenylsu...)copy SMILEScopy InChI
Affinity DataKi:  2.5nMAssay Description:Inhibition of [3H]-paroxetine binding to serotonin transporter (SERT) of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TH8M15PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
INSERM

Curated by ChEMBL
LigandPNGBDBM50110786(CHEMBL22259 | [2-(4-Bromo-2-methoxymethyl-phenylsu...)copy SMILEScopy InChI
Affinity DataKi:  2.75nMAssay Description:Inhibition of [3H]-paroxetine binding to serotonin transporter (SERT) of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TH8M15PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£ d'Orl£ans

Curated by ChEMBL
LigandPNGBDBM50513604(CHEMBL4441856)copy SMILEScopy InChI
Affinity DataKi:  2.80nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from alpha7 nAChR in Wistar rat brain membrane incubated for 3 hrs by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49V3XPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
INSERM

Curated by ChEMBL
LigandPNGBDBM50006774((2S,3S)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Displacement of [3H]- paroxetine from serotonin transporter (5-HTT) in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB7586PubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Universite Orleans

Curated by ChEMBL
LigandPNGBDBM50500421(CHEMBL3747344)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Displacement of [3H]BRL 43694 from human 5-HT3 receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TF01CWPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£ d'Orl£ans

Curated by ChEMBL
LigandPNGBDBM50500421(CHEMBL3747344)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAchR in rat frontal corticesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TF01CWPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£ d'Orl£ans

Curated by ChEMBL
LigandPNGBDBM50513576(CHEMBL4531375)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from alpha7 nAChR in Wistar rat brain membrane incubated for 3 hrs by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49V3XPubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Universite Orleans

Curated by ChEMBL
LigandPNGBDBM50500406(CHEMBL3746146)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Displacement of [3H]BRL 43694 from human 5-HT3 receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TF01CWPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
INSERM

Curated by ChEMBL
LigandPNGBDBM22166(3-(4-iodophenyl)tropane-2-carboxylic acid methyl e...)copy SMILEScopy InChI
Affinity DataKi:  3.10nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X928VCPubMed
TargetNorepinephrine transporter(RAT)
INSERM U316

Curated by PDSP Ki Database
LigandPNGBDBM22417(3-(2-methoxyphenoxy)-N-methyl-3-phenylpropan-1-ami...)copy SMILEScopy InChI
Affinity DataKi:  3.40nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X928VCPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
INSERM

Curated by ChEMBL
LigandPNGBDBM50178934(2-(2-((dimethylamino)methyl)phenylsulfinyl)-5-meth...)copy SMILEScopy InChI
Affinity DataKi:  4.15nMAssay Description:Displacement of [3H]paroxetine from SERTMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z037R6PubMed
TargetAmyloid-beta precursor protein [1-42](Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM50185987(2-(1-(6-((2-fluoroethyl)(methyl)amino)naphthalen-2...)copy SMILEScopy InChI
Affinity DataKi:  4.60nMAssay Description:Table 5: Fresh solutions of the test compounds (2.5 mM in DMSO) are diluted in PBS pH7.4, at concentrations between 0.5 nM and 5 μM in the prese...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC42NCUS Patent
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM481149(US10906900, Reference 22a)copy SMILEScopy InChI
Affinity DataKi:  4.61nMAssay Description:Table 5: Fresh solutions of the test compounds (2.5 mM in DMSO) are diluted in PBS pH7.4, at concentrations between 0.5 nM and 5 μM in the prese...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC42NCUS Patent
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM481149(US10906900, Reference 22a)copy SMILEScopy InChI
Affinity DataKi:  4.70nMAssay Description:Table 5: Fresh solutions of the test compounds (2.5 mM in DMSO) are diluted in PBS pH7.4, at concentrations between 0.5 nM and 5 μM in the prese...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC42NCUS Patent
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£ d'Orl£ans

Curated by ChEMBL
LigandPNGBDBM50513581(CHEMBL4471476)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from alpha7 nAChR in Wistar rat brain membrane incubated for 3 hrs by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49V3XPubMed
Displayed 1 to 50 (of 351 total ) | Next | Last >>
Jump to: