Compile Data Set for Download or QSAR
Found 69 with Last Name = 'chelur' and Initial = 's'
TargetAndrogen receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50057651(CHEMBL3326454)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Displacement of [3H]DHT from androgen receptor in human MDA-MB-435 cells after 30 minsMore data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50547958(CHEMBL4789918)copy SMILES
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged human IRAK4 expressed in baculovirus infected sf9 cells using biotinylated histone H3 as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8QB4PubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50547947(CHEMBL4760206)copy SMILES
Affinity DataIC50: 2.70nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged human IRAK4 expressed in baculovirus infected sf9 cells using biotinylated histone H3 as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8QB4PubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50547949(CHEMBL4743091)copy SMILES
Affinity DataIC50: 2.80nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged human IRAK4 expressed in baculovirus infected sf9 cells using biotinylated histone H3 as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8QB4PubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50547959(CHEMBL4750630)copy SMILES
Affinity DataIC50: 3.5nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged human IRAK4 expressed in baculovirus infected sf9 cells using biotinylated histone H3 as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8QB4PubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50547962(CHEMBL4784665)copy SMILES
Affinity DataIC50: 3.60nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged human IRAK4 expressed in baculovirus infected sf9 cells using biotinylated histone H3 as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8QB4PubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50547955(CHEMBL4796558)copy SMILES
Affinity DataIC50: 3.60nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged human IRAK4 expressed in baculovirus infected sf9 cells using biotinylated histone H3 as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8QB4PubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50547954(CHEMBL4763990)copy SMILES
Affinity DataIC50: 4.5nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged human IRAK4 expressed in baculovirus infected sf9 cells using biotinylated histone H3 as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8QB4PubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50547953(CHEMBL4790506)copy SMILES
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged human IRAK4 expressed in baculovirus infected sf9 cells using biotinylated histone H3 as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8QB4PubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50547961(CHEMBL4777409)copy SMILES
Affinity DataIC50: 6.5nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged human IRAK4 expressed in baculovirus infected sf9 cells using biotinylated histone H3 as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8QB4PubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50547946(CHEMBL4757687)copy SMILES
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged human IRAK4 expressed in baculovirus infected sf9 cells using biotinylated histone H3 as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8QB4PubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50547963(CHEMBL4757349)copy SMILES
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged human IRAK4 expressed in baculovirus infected sf9 cells using biotinylated histone H3 as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8QB4PubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50547948(CHEMBL4742305)copy SMILES
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged human IRAK4 expressed in baculovirus infected sf9 cells using biotinylated histone H3 as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8QB4PubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50547950(CHEMBL4748475)copy SMILES
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged human IRAK4 expressed in baculovirus infected sf9 cells using biotinylated histone H3 as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8QB4PubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50547965(CHEMBL4741488)copy SMILES
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged human IRAK4 expressed in baculovirus infected sf9 cells using biotinylated histone H3 as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8QB4PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM200372(US10011599, Example 1A | US9227969, 1A | US9629836...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of wild-type human partial length TRKA (G475 to G790 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q225JPubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50547964(CHEMBL4783351)copy SMILES
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged human IRAK4 expressed in baculovirus infected sf9 cells using biotinylated histone H3 as...More data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50547952(CHEMBL4757094)copy SMILES
Affinity DataIC50: 42nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged human IRAK4 expressed in baculovirus infected sf9 cells using biotinylated histone H3 as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8QB4PubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50547956(CHEMBL4748082)copy SMILES
Affinity DataIC50: 55nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged human IRAK4 expressed in baculovirus infected sf9 cells using biotinylated histone H3 as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8QB4PubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50547947(CHEMBL4760206)copy SMILES
Affinity DataIC50: 59nMAssay Description:Inhibition of IRAK4 in human THP-1 cells assessed as inhibition of LTA-induced TNF-alpha production preincubated for 60 mins followed by LTA stimulat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8QB4PubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50547960(CHEMBL4755398)copy SMILES
Affinity DataIC50: 63nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged human IRAK4 expressed in baculovirus infected sf9 cells using biotinylated histone H3 as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8QB4PubMed
LigandPNGBDBM50585940(CHEMBL5090765)copy SMILES
Affinity DataIC50: 70nMAssay Description:Inhibition of full-length human MEK1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q225JPubMed
LigandPNGBDBM50585939(CHEMBL5094993)copy SMILES
Affinity DataIC50: 100nMAssay Description:Inhibition of full-length human MEK1 by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q225JPubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50547948(CHEMBL4742305)copy SMILES
Affinity DataIC50: 103nMAssay Description:Inhibition of IRAK4 in human THP-1 cells assessed as inhibition of LTA-induced TNF-alpha production preincubated for 60 mins followed by LTA stimulat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8QB4PubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50547951(CHEMBL4791469)copy SMILES
Affinity DataIC50: 104nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged human IRAK4 expressed in baculovirus infected sf9 cells using biotinylated histone H3 as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8QB4PubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50547965(CHEMBL4741488)copy SMILES
Affinity DataIC50: 233nMAssay Description:Inhibition of IRAK4 in human THP-1 cells assessed as inhibition of LTA-induced TNF-alpha production preincubated for 60 mins followed by LTA stimulat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8QB4PubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50547964(CHEMBL4783351)copy SMILES
Affinity DataIC50: 270nMAssay Description:Inhibition of IRAK4 in human MV4-11 cells assessed as modulation of phospho-IRAK1 level by immunoblotting analysisMore data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50547945(CHEMBL4790504)copy SMILES
Affinity DataIC50: 397nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged human IRAK4 expressed in baculovirus infected sf9 cells using biotinylated histone H3 as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8QB4PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))TBA
LigandPNGBDBM50585939(CHEMBL5094993)copy SMILES
Affinity DataIC50: 500nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q225JPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))TBA
LigandPNGBDBM50585942(CHEMBL5092411)copy SMILES
Affinity DataIC50: 500nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q225JPubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50547957(CHEMBL4790895)copy SMILES
Affinity DataIC50: 505nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged human IRAK4 expressed in baculovirus infected sf9 cells using biotinylated histone H3 as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8QB4PubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50547964(CHEMBL4783351)copy SMILES
Affinity DataIC50: 514nMAssay Description:Inhibition of IRAK4 in human THP-1 cells assessed as inhibition of LTA-induced TNF-alpha production preincubated for 60 mins followed by LTA stimulat...More data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50547964(CHEMBL4783351)copy SMILES
Affinity DataIC50: 696nMAssay Description:Inhibition of IRAK4 in human whole blood assessed as inhibition of TLR5-mediated FLA-ST-induced IL-6 release preincubated for 1 hr followed by FLA-ST...More data for this Ligand-Target Pair
TargetProgesterone receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50057651(CHEMBL3326454)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Binding affinity to progesterone receptor (unknown origin) incubated for 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB768MPubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50547944(CHEMBL4788562)copy SMILES
Affinity DataIC50: 797nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged human IRAK4 expressed in baculovirus infected sf9 cells using biotinylated histone H3 as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8QB4PubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50547964(CHEMBL4783351)copy SMILES
Affinity DataIC50: 989nMAssay Description:Inhibition of IRAK4 in human whole blood assessed as inhibition of TLR2-mediated LTA-induced IL-6 release preincubated for 1 hr followed by LTA stimu...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50057651(CHEMBL3326454)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to estrogen receptor (unknown origin) incubated for 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB768MPubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50547967(CHEMBL4757221)copy SMILES
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of IRAK4 in human THP-1 cells assessed as inhibition of LTA-induced TNF-alpha production preincubated for 60 mins followed by LTA stimulat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8QB4PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50057651(CHEMBL3326454)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to glucocorticoid receptor (unknown origin) incubated for 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB768MPubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50547966(CHEMBL4747796)copy SMILES
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of IRAK4 in human THP-1 cells assessed as inhibition of LTA-induced TNF-alpha production preincubated for 60 mins followed by LTA stimulat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8QB4PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))TBA
LigandPNGBDBM50585943(CHEMBL5076921)copy SMILES
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q225JPubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50547964(CHEMBL4783351)copy SMILES
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibition of IRAK4 in human whole blood assessed as inhibition of IL-1R-mediated IL-1beta-induced IL-6 release preincubated for 1 hr followed by IL-...More data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50547943(CHEMBL4789126)copy SMILES
Affinity DataIC50: 1.49E+3nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged human IRAK4 expressed in baculovirus infected sf9 cells using biotinylated histone H3 as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetCytochrome P450 3A4(Homo sapiens (Human))TBA
LigandPNGBDBM50585941(CHEMBL5089865)copy SMILES
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q225JPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))TBA
LigandPNGBDBM200455(US10011599, Example 84 | US9227969, 84)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q225JPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))TBA
LigandPNGBDBM200439(US10011599, Example 68 | US9227969, 68 | US9629836...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q225JPubMed
LigandPNGBDBM50585938(CHEMBL5087942)copy SMILES
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of full-length human MEK1 by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q225JPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))TBA
LigandPNGBDBM200425(US10011599, Example 52 | US9227969, 52)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q225JPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))TBA
LigandPNGBDBM50585945(CHEMBL5088062)copy SMILES
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q225JPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))TBA
LigandPNGBDBM200372(US10011599, Example 1A | US9227969, 1A | US9629836...)copy SMILEScopy InChI
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q225JPubMed
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