Compile Data Set for Download or QSAR
Found 319 with Last Name = 'epshteyn' and Initial = 's'
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402421(CHEMBL2208035)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402413(CHEMBL2208032)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402409(CHEMBL2208034)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402412(CHEMBL2208033)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50310998(CHEMBL1077458 | N-(4-(2-(4-morpholinophenylamino)p...)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402416(CHEMBL2208025)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402424(CHEMBL2208027)copy SMILEScopy InChI
Affinity DataIC50: 4.40nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402415(CHEMBL2208028)copy SMILEScopy InChI
Affinity DataIC50: 5.10nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402411(CHEMBL2207759)copy SMILEScopy InChI
Affinity DataIC50: 5.20nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402420(CHEMBL2207758)copy SMILEScopy InChI
Affinity DataIC50: 5.70nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402417(CHEMBL2208024)copy SMILEScopy InChI
Affinity DataIC50: 6.5nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402427(CHEMBL2207766)copy SMILEScopy InChI
Affinity DataIC50: 6.90nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402414(CHEMBL2208031)copy SMILEScopy InChI
Affinity DataIC50: 8.70nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402410(CHEMBL2207760)copy SMILEScopy InChI
Affinity DataIC50: 9.10nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402426(CHEMBL2207767)copy SMILEScopy InChI
Affinity DataIC50: 11.1nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402419(CHEMBL2207764)copy SMILEScopy InChI
Affinity DataIC50: 12.6nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402418(CHEMBL2208023)copy SMILEScopy InChI
Affinity DataIC50: 12.8nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402423(CHEMBL2208029)copy SMILEScopy InChI
Affinity DataIC50: 39.6nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402421(CHEMBL2208035)copy SMILEScopy InChI
Affinity DataIC50: 61.7nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
LigandPNGBDBM50429897(CHEMBL2333379)copy SMILEScopy InChI
Affinity DataIC50: 89nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed
LigandPNGBDBM50429896(CHEMBL2332918)copy SMILEScopy InChI
Affinity DataIC50: 89nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402431(CHEMBL2207761)copy SMILEScopy InChI
Affinity DataIC50: 104nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402415(CHEMBL2208028)copy SMILEScopy InChI
Affinity DataIC50: 105nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402409(CHEMBL2208034)copy SMILEScopy InChI
Affinity DataIC50: 125nMAssay Description:Inhibition of PDGFRBMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402428(CHEMBL2207765)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402409(CHEMBL2208034)copy SMILEScopy InChI
Affinity DataIC50: 134nMAssay Description:Inhibition of JAK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
LigandPNGBDBM50429895(CHEMBL2333375)copy SMILEScopy InChI
Affinity DataIC50: 137nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402409(CHEMBL2208034)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of FLT3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402412(CHEMBL2208033)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova Limited

Curated by ChEMBL
LigandPNGBDBM50111316(8-[4-(3,6-Dioxo-5-{4-[(thiophene-2-carbonyl)-amino...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W958HQPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402409(CHEMBL2208034)copy SMILEScopy InChI
Affinity DataIC50: 214nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402409(CHEMBL2208034)copy SMILEScopy InChI
Affinity DataIC50: 226nMAssay Description:Inhibition of c-KITMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
LigandPNGBDBM50429893(CHEMBL2333373)copy SMILEScopy InChI
Affinity DataIC50: 238nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed
LigandPNGBDBM50429892(CHEMBL2333374)copy SMILEScopy InChI
Affinity DataIC50: 259nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova Limited

Curated by ChEMBL
LigandPNGBDBM50111273(6-Benzo[b]thiophen-2-yl-4-hydroxy-2-oxo-1,2-dihydr...)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by complex assay.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W958HQPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402414(CHEMBL2208031)copy SMILEScopy InChI
Affinity DataIC50: 298nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova Limited

Curated by ChEMBL
LigandPNGBDBM50111280(1-(4-Chloro-phenyl)-4-hydroxy-2-oxo-2,5-dihydro-1H...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by complex assay.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W958HQPubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova Limited

Curated by ChEMBL
LigandPNGBDBM50111298(8-{4-[(7-Benzo[b]thiophen-2-yl-4-hydroxy-2-oxo-1,2...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W958HQPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402413(CHEMBL2208032)copy SMILEScopy InChI
Affinity DataIC50: 307nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402409(CHEMBL2208034)copy SMILEScopy InChI
Affinity DataIC50: 314nMAssay Description:Inhibition of P70S6KMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402413(CHEMBL2208032)copy SMILEScopy InChI
Affinity DataIC50: 328nMAssay Description:Inhibition of JAK2 in HEL 92.1.7 cells assessed as inhibition of STAT1 phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402409(CHEMBL2208034)copy SMILEScopy InChI
Affinity DataIC50: 348nMAssay Description:Inhibition of TYK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402420(CHEMBL2207758)copy SMILEScopy InChI
Affinity DataIC50: 368nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
TargetMitogen-activated protein kinase kinase kinase 9(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402409(CHEMBL2208034)copy SMILEScopy InChI
Affinity DataIC50: 370nMAssay Description:Inhibition of MLK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402409(CHEMBL2208034)copy SMILEScopy InChI
Affinity DataIC50: 375nMAssay Description:Inhibition of IKKbetaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402409(CHEMBL2208034)copy SMILEScopy InChI
Affinity DataIC50: 386nMAssay Description:Inhibition of JAK2 in HEL 92.1.7 cells assessed as inhibition of STAT1 phosphorylationMore data for this Ligand-Target Pair
LigandPNGBDBM50429891(CHEMBL2333366)copy SMILEScopy InChI
Affinity DataIC50: 398nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402415(CHEMBL2208028)copy SMILEScopy InChI
Affinity DataIC50: 447nMAssay Description:Inhibition of JAK2 in HEL 92.1.7 cells assessed as inhibition of STAT3 phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402413(CHEMBL2208032)copy SMILEScopy InChI
Affinity DataIC50: 452nMAssay Description:Inhibition of JAK2 in HEL 92.1.7 cells assessed as inhibition of STAT3 phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
LigandPNGBDBM50429890(CHEMBL2331575)copy SMILEScopy InChI
Affinity DataIC50: 459nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed
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